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1. Ahmed MS, Øie E, Vinge LE, Yndestad A, Øystein Andersen G, Andersson Y, Attramadal T, Attramadal H: Connective tissue growth factor--a novel mediator of angiotensin II-stimulated cardiac fibroblast activation in heart failure in rats. J Mol Cell Cardiol; 2004 Mar;36(3):393-404
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  • The induction of myocardial CTGF mRNA was shown to transcend from early post-infarction HF to chronic HF.
  • In subsequent experiments rats subjected to MI were randomized to treatment with the AT1 angiotensin receptor antagonist losartan (12.5 mg/kg b.i.d. per os) or vehicle.
  • Losartan attenuated ventricular hypertrophy, improved hemodynamics, and prevented the induction of myocardial CTGF mRNA observed in rats post-MI.
  • Real-time reverse transcription-polymerase chain reaction and western blot analysis demonstrate that Ang II induces rapid, AT1 receptor-mediated elevations of CTGF mRNA and protein in rat cardiac fibroblasts.

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  • (PMID = 15010278.001).
  • [ISSN] 0022-2828
  • [Journal-full-title] Journal of molecular and cellular cardiology
  • [ISO-abbreviation] J. Mol. Cell. Cardiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiotensin II Type 1 Receptor Blockers; 0 / Anti-Arrhythmia Agents; 0 / Ctgf protein, rat; 0 / Immediate-Early Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / RNA, Messenger; 0 / Receptor, Angiotensin, Type 1; 0 / Vasoconstrictor Agents; 11128-99-7 / Angiotensin II; 139568-91-5 / Connective Tissue Growth Factor; JMS50MPO89 / Losartan
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2. Paolini M, Pozzetti L, Silingardi P, Della Croce C, Bronzetti G, Cantelli-Forti G: Isolation of a novel metabolizing system enriched in phase-II enzymes for short-term genotoxicity bioassays. Mutat Res; 1998 Mar 30;413(3):205-17
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  • Murine S9 liver fractions isolated from mice fed 7.5 g kg-1 2(3)-tert-Butyl-4-hydroxyanisole (BHA) for 3 weeks were tested to determine: (a) the profile of both phase-I and phase-II xenobiotic metabolizing enzymes;.
  • For post-oxidative enzymes, the S9 expressed high levels of glutathione S-transferases (up to 12-fold increase), glutathione S-epoxide-transferase (up to 2.6-fold), UDP-glucuronosyl transferase (up to 5.3-fold) and epoxide hydrolase (up to 2.6-fold) activities, as compared to untreated mice.
  • Because a number of chemicals are activated by either oxidative or post-oxidative enzymes, the use of metabolizing biosystems, with an enhanced phase-II pathway, together with classical S9 fractions, can improve the sensitivity of the assay in detecting unknown genotoxins.

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  • (PMID = 9651530.001).
  • [ISSN] 0027-5107
  • [Journal-full-title] Mutation research
  • [ISO-abbreviation] Mutat. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Bromobenzenes; 0 / Carcinogens; 0 / Chlorobenzenes; 0 / DNA Adducts; 25013-16-5 / Butylated Hydroxyanisole; 6PJ93I88XL / 2-dichlorobenzene; 9035-51-2 / Cytochrome P-450 Enzyme System; 9991W3M5HZ / 1,4-dibromobenzene; D149TYB5MK / 4-dichlorobenzene
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3. White AM, Best PJ: Effects of ethanol on hippocampal place-cell and interneuron activity. Brain Res; 2000 Sep 8;876(1-2):154-65
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  • [Title] Effects of ethanol on hippocampal place-cell and interneuron activity.
  • The present study examines the effects of ethanol on hippocampal place-cell and interneuron activity in freely-behaving rats.
  • Following sufficient time for recovery (minimum of 3 h post injection), cellular activity was monitored for an additional 15-min period.

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  • (PMID = 10973604.001).
  • [ISSN] 0006-8993
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 3K9958V90M / Ethanol
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4. Breck O, Bjerkås E, Campbell P, Rhodes JD, Sanderson J, Waagbø R: Histidine nutrition and genotype affect cataract development in Atlantic salmon, Salmo salar L. J Fish Dis; 2005 Jun;28(6):357-71
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  • Three experimental diets were fed: (i) a control diet (CD) with 110 mg kg(-1) Fe and 11.7 g kg(-1) His;.
  • (ii) CD supplemented with crystalline His to a level of 18 g kg(-1) (HD); and (iii) HD with added iron up to 220 mg kg(-1) (HID).
  • Groups fed HD or HID had higher lens levels of His and N-acetyl histidine (NAH), the latter showing a marked increase post-smoltification (P < 0.05).

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  • (PMID = 15960659.001).
  • [ISSN] 0140-7775
  • [Journal-full-title] Journal of fish diseases
  • [ISO-abbreviation] J. Fish Dis.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemoglobins; 4QD397987E / Histidine; E1UOL152H7 / Iron; HDQ4N37UGV / Anserine
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5. Tenberken O, Mikler J, Hill I, Weatherby K, Thiermann H, Worek F, Reiter G: Toxicokinetics of tabun enantiomers in anaesthetized swine after intravenous tabun administration. Toxicol Lett; 2010 Oct 5;198(2):177-81
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  • Blood samples were taken for gas chromatographic-mass spectrometric determination of the tabun enantiomers and for measurement of the activity of red blood cell acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BChE).
  • In the terminal phase a remarkable difference was found, with terminal half lives of 11.5min for (+)-tabun and 23.1min for (-)-tabun. (+)-Tabun showed a markedly longer persistence in vivo than (+)-enantiomers of other G-type nerve agents and could be detected in all swine at least up to 30min post-injection, (-)-tabun at least up to 90min post-injection.

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20599598.001).
  • [ISSN] 1879-3169
  • [Journal-full-title] Toxicology letters
  • [ISO-abbreviation] Toxicol. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Chemical Warfare Agents; 0 / Organophosphates; EC 3.1.1.- / Butyrylcholinesterase; EC 3.1.1.7 / Acetylcholinesterase; S45M750QSH / tabun
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6. Thapliyal A, Vasudevan P, Dastidar MG, Tandon M, Mishra S: Irrigation with domestic wastewater: responses on growth and yield of ladyfinger Abelmoschus esculentus and on soil nutrients. J Environ Biol; 2011 Sep;32(5):645-51
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  • The organic matter (%), NO3-N and PO4(3-) (mg kg(-1)) content post harvest soil was found to be 3.4, 71, 90 under T1 and 2.9, 52, 63 under T2 respectively.

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  • (PMID = 22319883.001).
  • [ISSN] 0254-8704
  • [Journal-full-title] Journal of environmental biology
  • [ISO-abbreviation] J Environ Biol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Metals, Heavy; 0 / Soil
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7. Schulteis G, Chiang D, Archer C: Relative potency of the opioid antagonists naloxone and 6-alpha-naloxol to precipitate withdrawal from acute morphine dependence varies with time post-antagonist. Pharmacol Biochem Behav; 2009 Mar;92(1):157-63
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  • [Title] Relative potency of the opioid antagonists naloxone and 6-alpha-naloxol to precipitate withdrawal from acute morphine dependence varies with time post-antagonist.
  • Male Wistar rats trained to respond on a lever for food reward received pretreatment with either Vehicle (Morphine-Naïve), a single subcutaneous (SC) injection of 5.6 mg/kg morphine (Single Morphine), or two morphine injections at 24 h intervals (Repeat Morphine), with varying doses of naloxone or 6-alpha-naloxol injected SC 4 h post-morphine and 5 min prior to the 30 min test session.
  • Examination of the relative potency of these antagonists in the Early Phase of operant testing (5-15 min post-antagonist) revealed an even greater 100-fold potency difference between naloxone and 6-alpha-naloxol, but in the Late Phase of testing (25-35 min post-antagonist), this had declined to a 9-fold potency difference, comparable to the relative potency of naloxone to 6-alpha-naloxol under Morphine-Naïve conditions.

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  • (PMID = 19061911.001).
  • [ISSN] 0091-3057
  • [Journal-full-title] Pharmacology, biochemistry, and behavior
  • [ISO-abbreviation] Pharmacol. Biochem. Behav.
  • [Language] ENG
  • [Grant] United States / NIDA NIH HHS / DA / DA10475; United States / NIDA NIH HHS / DA / R01 DA010475; United States / NIDA NIH HHS / DA / R01 DA010475-09; United States / NIDA NIH HHS / DA / R29 DA010475; United States / NIDA NIH HHS / DA / DA010475-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Narcotic Antagonists; 20410-95-1 / 6 alpha-naloxol; 36B82AMQ7N / Naloxone
  • [Other-IDs] NLM/ NIHMS95893; NLM/ PMC2652854
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8. Sancheti G, Goyal P: Modulatory influence of Rosemarinus officinalis on DMBA-induced mouse skin tumorigenesis. Asian Pac J Cancer Prev; 2006 Apr-Jun;7(2):331-5
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  • / day at pre, peri and post-initiational phases, was found to be effective in decreasing the tumor incidence (50, 41.7, 58.3%, respectively) in comparison to the control (100%).

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  • (PMID = 16839234.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Plant Extracts; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene; GAN16C9B8O / Glutathione
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9. Ishikawa G, Koya Y, Tanaka H, Nagakura Y: Long-term analgesic effect of a single dose of anti-NGF antibody on pain during motion without notable suppression of joint edema and lesion in a rat model of osteoarthritis. Osteoarthritis Cartilage; 2015 Jun;23(6):925-32
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  • RESULTS: AS2886401-00 administered at 0.3 or 1 mg/kg on Day 3 post-MIA injection resulted in a statistically significant improvement in gait imbalance even on Day 35.
  • When gait measurement was set on Week 3 post-MIA administration, administration of the antibody at a timing close to the gait measurement, i.e., 1 or 24 h prior to the measurement, was less effective.

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  • [Copyright] Copyright © 2015 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 25677108.001).
  • [ISSN] 1522-9653
  • [Journal-full-title] Osteoarthritis and cartilage
  • [ISO-abbreviation] Osteoarthr. Cartil.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Analgesics, Non-Narcotic; 0 / Antibodies, Monoclonal; 0 / NGF protein, human; 9061-61-4 / Nerve Growth Factor
  • [Keywords] NOTNLM ; Antibody of nerve growth factor / Joint edema and lesion / Osteoarthritis / Pain during motion / Sodium monoiodoacetate
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10. Hamidi GA, Ramezani MH, Arani MN, Talaei SA, Mesdaghinia A, Banafshe HR: Ethosuximide reduces allodynia and hyperalgesia and potentiates morphine effects in the chronic constriction injury model of neuropathic pain. Eur J Pharmacol; 2012 Jan 15;674(2-3):260-4
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  • The cold-and mechano-allodynia and thermal hyperalgesia were measured prior to surgery (the day 0) and 3, 5, 7, 14 and 21 days post surgery.

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  • [Copyright] Copyright © 2011 Elsevier B.V. All rights reserved.
  • (PMID = 22134003.001).
  • [ISSN] 1879-0712
  • [Journal-full-title] European journal of pharmacology
  • [ISO-abbreviation] Eur. J. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Analgesics, Opioid; 0 / Calcium Channel Blockers; 5SEH9X1D1D / Ethosuximide; 76I7G6D29C / Morphine
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11. Stoyanov M, Muller H, Borner U, Hempelmann G: [Value of morphine derivatives administered by the peridural route per- and postoperatively]. Ann Anesthesiol Fr; 1981;22(4):311-6
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  • [Title] [Value of morphine derivatives administered by the peridural route per- and postoperatively].
  • [Transliterated title] L'intérêt des dérivés morphiniques par voie péridurale en per et post-opératoire.

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  • (PMID = 6119939.001).
  • [ISSN] 0003-4061
  • [Journal-full-title] Annales de l'anesthésiologie française
  • [ISO-abbreviation] Ann Anesthesiol Fr
  • [Language] fre
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] FRANCE
  • [Chemical-registry-number] 0 / Morphine Derivatives; UF599785JZ / Fentanyl
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12. Hemre GI, Lock EJ, Olsvik PA, Hamre K, Espe M, Torstensen BE, Silva J, Hansen AC, Waagbø R, Johansen JS, Sanden M, Sissener NH: Atlantic salmon (&lt;i&gt;Salmo salar&lt;/i&gt;) require increased dietary levels of B-vitamins when fed diets with high inclusion of plant based ingredients. PeerJ; 2016;4:e2493
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  • Aiming to re-evaluate current recommendations for nutrient supplementations when Atlantic salmon are fed diets based on plant ingredients, two regression experiments, with parr and post-smolt, were conducted.
  • Post-smolt fed the same diets during five months showed a doubling of weight, but did not respond to the variation in NP to the same extent as parr.

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  • (PMID = 27703849.001).
  • [ISSN] 2167-8359
  • [Journal-full-title] PeerJ
  • [ISO-abbreviation] PeerJ
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Atlantic salmon / B-vitamin recommendations / Plant based feed
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13. Dousset B, Valverde A, Houssin D, Bernard O, Chapuis Y: [Ascites after liver transplantation in children]. Ann Radiol (Paris); 1994;37(5):386-90
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  • The diagnosis of post-LT ascites was defined as a drainage rate greater than 25 ml/kg/day (or- > 500 ml/day) persisting for at least 72 hours after removal of the drains.

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  • (PMID = 7993026.001).
  • [ISSN] 0003-4185
  • [Journal-full-title] Annales de radiologie
  • [ISO-abbreviation] Ann Radiol (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] FRANCE
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14. Rodríguez-Pérez J, Wiegand K, Ward D: Interaction between ungulates and bruchid beetles and its effect on Acacia trees: modeling the costs and benefits of seed dispersal to plant demography. Oecologia; 2011 Sep;167(1):97-105
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  • Here we studied how ungulates (acting as both seed dispersers and herbivores) and bruchid beetles (post-dispersal seed predators) modulate the population dynamics of A. raddiana, a keystone species in the Middle East.
  • Managing and restoring acacia seed dispersers is key to conserving acacia populations, because low-to-medium seed removal could quickly restore their regeneration capacity.

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  • (PMID = 21442280.001).
  • [ISSN] 1432-1939
  • [Journal-full-title] Oecologia
  • [ISO-abbreviation] Oecologia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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15. Jaakson H, Ling K, Samarütel J, Ilves A, Kaart T, Kärt O: Field trial on glucose-induced insulin and metabolite responses in Estonian Holstein and Estonian Red dairy cows in two herds. Acta Vet Scand; 2010;52:4
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  • BACKGROUND: Insulin secretion and tissue sensitivity to insulin is considered to be one of the factors controlling lipid metabolism post partum.
  • METHODS: The study was carried out using the glucose tolerance test (GTT) performed at 31 +/- 1.9 days post partum during negative energy balance.
  • Applying the MIXED Procedure with the SAS System the basal concentration of cholesterol, and basal concentration and concentrations at post-infusion time points for other metabolites, area under the curve (AUC) for glucose and insulin, clearance rate (CR) for glucose, and maximum increase from basal concentration for glucose and insulin were compared between breeds.

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  • (PMID = 20089161.001).
  • [ISSN] 1751-0147
  • [Journal-full-title] Acta veterinaria Scandinavica
  • [ISO-abbreviation] Acta Vet. Scand.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Fatty Acids, Nonesterified; 0 / Insulin; 0 / Sweetening Agents; 0 / Triglycerides; 97C5T2UQ7J / Cholesterol; IY9XDZ35W2 / Glucose; TZP1275679 / 3-Hydroxybutyric Acid
  • [Other-IDs] NLM/ PMC2841601
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16. Rossi MC, Perozzi C, Consorti C, Almonti T, Foglini P, Giostra N, Nanni P, Talevi S, Bartolomei D, Vespasiani G: An interactive diary for diet management (DAI): a new telemedicine system able to promote body weight reduction, nutritional education, and consumption of fresh local produce. Diabetes Technol Ther; 2010 Aug;12(8):641-7
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  • BACKGROUND: The aim of this multicenter, longitudinal, single-arm, pre-post comparison was to test a telemedicine system able to promote body weight reduction, nutritional education, and consumption of fresh local produce.
  • On average, each patient recognized and chose fresh local vegetables eight times per week during the follow-up.

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  • (PMID = 20615106.001).
  • [ISSN] 1557-8593
  • [Journal-full-title] Diabetes technology & therapeutics
  • [ISO-abbreviation] Diabetes Technol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. de Andrade DC, de Magalhães Souza SC, de Carvalho JF, Takayama L, Borges CT, Aldrighi JM, Pereira RM: High frequency of osteoporosis and fractures in women with dermatomyositis/polymyositis. Rheumatol Int; 2012 Jun;32(6):1549-53
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  • Comparing DM/PM patients with (n = 17) and without (n = 23) osteoporosis/fractures, significant differences were observed regarding age [56.8 (11.9) vs. 48.3 (13.2) years, P = 0.042], weight [62.05 (13.56) vs. 71.51 (11.46) kg, P = 0.022] and frequency of post menopausal women (94.1 vs. 65.2%, P = 0.0002).
  • No differences were observed concerning height, lean mass, total fat mass, disease activity, mean value of creatine kinase, cumulative glucocorticoid dose, or bisphosphonate use.


18. Kebriaei P, Winter JN, Laport GG, Le Beau MM, Dewald G, Larson RA: Multiple unrelated clonal abnormalities in host bone marrow cells after allogeneic stem cell transplantation. Leuk Res; 2004 May;28(5):537-40
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  • [Title] Multiple unrelated clonal abnormalities in host bone marrow cells after allogeneic stem cell transplantation.
  • Post-stem cell transplant (SCT) immunosuppression consisted of antithymocyte globulin, cyclosporine, and prednisone, and was discontinued after 7 months.
  • The donor graft was rejected 2 years post-SCT.
  • At 7 years post-SCT, he is clinically well with normal blood counts and no evidence of CML or myelodysplasia despite the presence over 6 years of multiple clones with balanced translocations and deletions in host bone marrow cells.
  • [MeSH-major] Bone Marrow Cells / pathology. Chromosome Aberrations. Hematopoietic Stem Cell Transplantation. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy

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  • (PMID = 15068908.001).
  • [ISSN] 0145-2126
  • [Journal-full-title] Leukemia research
  • [ISO-abbreviation] Leuk. Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA-14599; United States / NCI NIH HHS / CA / CA-40046
  • [Publication-type] Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
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19. Eisele TA, Sinnhuber RO, Nixon JE: Dietary antioxidant effects on the hepatic mixed-function oxidase system of rainbow trout (Salmo Gairdneri). Food Chem Toxicol; 1983 Jun;21(3):273-7
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  • NADPH-cytochrome c reductase was elevated 1.2-1.3 times over the control value with dietary BHA, TBHQ and BHT, but was lowered with EQ. p-Nitroanisole-O-demethylase activity was completely suppressed in antioxidant-fed trout.
  • The content of post-mitochondrial acid-soluble sulphydryl groups was 42% lower in BHA- and BHT-fed trout.

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  • (PMID = 6602752.001).
  • [ISSN] 0278-6915
  • [Journal-full-title] Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • [ISO-abbreviation] Food Chem. Toxicol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 25766; United States / NIEHS NIH HHS / ES / ES 00541; United States / NIEHS NIH HHS / ES / ES 00550
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Aflatoxins; 0 / Antioxidants; 0 / Benzopyrenes; 1P9D0Z171K / Butylated Hydroxytoluene; 25013-16-5 / Butylated Hydroxyanisole; EC 1.- / Mixed Function Oxygenases; EC 1.- / Oxidoreductases; EC 1.13.- / Oxygenases; EC 1.14.13.- / 7-Alkoxycoumarin O-Dealkylase; EC 3.3.2.- / Epoxide Hydrolases
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20. Hansen TM, Nielsen H, Bernth N, Moos T: Expression of ferritin protein and subunit mRNAs in normal and iron deficient rat brain. Brain Res Mol Brain Res; 1999 Mar 5;65(2):186-97
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  • In non-neuronal tissue, ferritin subunit mRNAs are regulated by post-transcriptional mechanisms leading to decreased ferritin protein synthesis during iron deficiency.
  • This treatment reduced brain iron levels from approximately 57 to 26 microgram/g.

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  • [Copyright] Copyright 1999 Elsevier Science B.V.
  • (PMID = 10064889.001).
  • [ISSN] 0169-328X
  • [Journal-full-title] Brain research. Molecular brain research
  • [ISO-abbreviation] Brain Res. Mol. Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / DNA Primers; 0 / RNA, Messenger; 9007-73-2 / Ferritins; E1UOL152H7 / Iron
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21. Gong Y, Cui L, Minuk GY: Effects of acute and chronic ethanol exposure on the hepatic gamma-aminobutyric acid transport system in rats. Alcohol; 1999 Nov;19(3):213-8
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  • To determine the mechanism(s) whereby ethanol increases GABAergic activity in the liver, we documented the effects of acute (5 g/kg x 1) and chronic (36% of total calories over 6 weeks) ethanol exposure as well as exogenous GABA (500 microg/g body weight) administration on GABA transport protein (GABA-TP) mRNA expression in the livers of adult male Sprague-Dawley rats at various times (0-72 h) post 70% partial hepatectomy (PHx).
  • The results of the study revealed that compared to saline-exposed controls, acute but not chronic ethanol exposure resulted in significant decreases in GABA-TP mRNA expression at 12, 24, and 48 h post PHx (saline exposed, 1.04 +/- 0.06, 1.19 +/- 0.21, and 1.15 +/- 0.05. vs. acute ethanol exposed, 0.80 +/- 0.16, 0.88 +/- 0.09, and 0.86 +/- 0.16 optical density units, p < 0.01, 0.05, and 0.05, respectively).

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  • (PMID = 10580510.001).
  • [ISSN] 0741-8329
  • [Journal-full-title] Alcohol (Fayetteville, N.Y.)
  • [ISO-abbreviation] Alcohol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Carrier Proteins; 0 / Central Nervous System Depressants; 0 / GABA Plasma Membrane Transport Proteins; 0 / Membrane Proteins; 0 / Membrane Transport Proteins; 0 / Organic Anion Transporters; 0 / RNA, Messenger; 3K9958V90M / Ethanol; 56-12-2 / gamma-Aminobutyric Acid
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22. Lauriti G, Cananzi M, Pierro A, Eaton S, de Coppi P: Intestinal ischemia-reperfusion injury causes activation of bone marrow-derived progenitor cells. Eur J Pediatr Surg; 2009 Dec;19(6):366-9
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  • MATERIAL AND METHODS: After animal committee approval, anesthetized adult rats were divided into groups (n=4 per group) as follows: (i) control [C], (ii) 60 min intestinal ischemia [I], (iii) 60 min intestinal ischemia+360 min reperfusion [IR], (iv) 420 min sham operation [SH].
  • In addition, to determine whether rhG-CSF injection stimulates progenitor cell activation, two further groups were studied: (v) 60 min intestinal ischemia+360 min reperfusion with injection of 50 microg/kg rhG-CSF at reperfusion [IR-G];.
  • Data are expressed as median, range and IQR and compared using one-way ANOVA with Tukey's post-hoc test.
  • [MeSH-minor] Analysis of Variance. Animals. Bone Marrow Cells / metabolism. Cell Proliferation. Disease Models, Animal. Granulocyte Colony-Stimulating Factor / pharmacology. Male. Rats. Rats, Sprague-Dawley. Recombinant Proteins

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  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart-New York.
  • (PMID = 20013600.001).
  • [ISSN] 1439-359X
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Recombinant Proteins; 143011-72-7 / Granulocyte Colony-Stimulating Factor
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23. Földi R, Kovács R, Gesztelyi R, Kardos G, Berényi R, Juhász B, Szilágyi J, Mózes J, Majoros L: Comparison of in vitro and vivo efficacy of caspofungin against Candida parapsilosis, C. orthopsilosis, C. metapsilosis and C. albicans. Mycopathologia; 2012 Oct;174(4):311-8
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  • Kidney burden was analyzed using the Kruskal-Wallis test with Dunn's post-test.

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  • (PMID = 22565489.001).
  • [ISSN] 1573-0832
  • [Journal-full-title] Mycopathologia
  • [ISO-abbreviation] Mycopathologia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antifungal Agents; 0 / Echinocandins; 0 / Lipopeptides; F0XDI6ZL63 / caspofungin
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24. Aquilani R, Boschi F, Contardi A, Pistarini C, Achilli MP, Fizzotti G, Moroni S, Catapano M, Verri M, Pastoris O: Energy expenditure and nutritional adequacy of rehabilitation paraplegics with asymptomatic bacteriuria and pressure sores. Spinal Cord; 2001 Aug;39(8):437-41
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  • MATERIAL AND METHODS: Ten males with post-acute paraplegia aged 42.1+/-18.7 years.

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  • (PMID = 11512074.001).
  • [ISSN] 1362-4393
  • [Journal-full-title] Spinal cord
  • [ISO-abbreviation] Spinal Cord
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] AYI8EX34EU / Creatinine
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25. Geesink G, Sujang S, Koohmaraie M: Tenderness of pre- and post rigor lamb longissimus muscle. Meat Sci; 2011 Aug;88(4):723-6
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  • [Title] Tenderness of pre- and post rigor lamb longissimus muscle.
  • Lamb longissimus muscle (n=6) sections were cooked at different times post mortem (prerigor, at rigor, 1dayp.m., and 7 days p.m.) using two cooking methods.
  • Cooking prerigor and at rigor meat to 70 °C resulted in higher shear force values than their post rigor counterparts at 1 and 7 days p.m. (9.4 and 9.6 vs. 7.2 and 3.7 kg, respectively).
  • The mean sarcomere length in the post rigor samples was 1.44 μm.

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  • [Copyright] Copyright © 2011 Elsevier B.V. All rights reserved.
  • (PMID = 21450412.001).
  • [ISSN] 1873-4138
  • [Journal-full-title] Meat science
  • [ISO-abbreviation] Meat Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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26. Sombolos KI, Fragidis SK, Bamichas GI, Hatsiou VN, Rizos AK, Natse TA, Fytili CI: Subtherapeutic serum vancomycin concentrations during on-line hemodiafiltration. ASAIO J; 2011 Nov-Dec;57(6):507-10
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  • In group A patients, mean vancomycin concentrations were reduced by 50% (S(pre): 10.2 ± 1.4 μg/ml, S(post): 5.0 ± 0.9 μg/ml).

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  • (PMID = 21946313.001).
  • [ISSN] 1538-943X
  • [Journal-full-title] ASAIO journal (American Society for Artificial Internal Organs : 1992)
  • [ISO-abbreviation] ASAIO J.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 6Q205EH1VU / Vancomycin
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27. Zhang LM, Zhou WW, Ji YJ, Li Y, Zhao N, Chen HX, Xue R, Mei XG, Zhang YZ, Wang HL, Li YF: Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder. Psychopharmacology (Berl); 2015 Feb;232(4):663-72
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  • Furthermore, ketamine normalized the decreased BDNF level in the hippocampus in post-TDS rats.
  • [MeSH-major] Anti-Anxiety Agents / pharmacology. Excitatory Amino Acid Antagonists / pharmacology. Ketamine / pharmacology. Stress Disorders, Post-Traumatic / drug therapy

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  • (PMID = 25231918.001).
  • [ISSN] 1432-2072
  • [Journal-full-title] Psychopharmacology
  • [ISO-abbreviation] Psychopharmacology (Berl.)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Anxiety Agents; 0 / Brain-Derived Neurotrophic Factor; 0 / Excitatory Amino Acid Antagonists; 690G0D6V8H / Ketamine
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28. Chai PJ, Nassar R, Oakeley AE, Craig DM, Quick G Jr, Jaggers J, Sanders SP, Ungerleider RM, Anderson PA: Soluble complement receptor-1 protects heart, lung, and cardiac myofilament function from cardiopulmonary bypass damage. Circulation; 2000 Feb 8;101(5):541-6
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  • Complement inhibition effects on the post-CPB syndrome were tested with soluble complement receptor-1 (sCR1).
  • The post-CPB Hill coefficient of atrial myocardium was higher in the sCR1 group (2.88+/-0.29 vs 1.88+/-0.16, P=0.023).
  • CONCLUSIONS: sCR1 meaningfully moderates the post-CPB syndrome, supporting the hypothesis that complement activation contributes to this syndrome.

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  • (PMID = 10662752.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL20749; United States / NHLBI NIH HHS / HL / HL42250
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Protective Agents; 0 / Receptors, Complement; S88TT14065 / Oxygen; SY7Q814VUP / Calcium
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29. Badenhorst CE, Dawson B, Cox GR, Laarakkers CM, Swinkels DW, Peeling P: Acute dietary carbohydrate manipulation and the subsequent inflammatory and hepcidin responses to exercise. Eur J Appl Physiol; 2015 Dec;115(12):2521-30
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  • PURPOSE: To examine the effects of 24-h controlled carbohydrate intake on next day pre- and post-exercise inflammatory and hepcidin responses.
  • Subsequently, strict dietary control was enforced for 24 h, where low carbohydrate (LCHO 3 g kg(-1)) or high carbohydrate (HCHO 10 g kg(-1)) diets were provided.
  • Venous blood samples were collected pre-, immediately post- and 3-h post-exercise, which were analyzed for interleukin-6, serum iron, ferritin and hepcidin.
  • RESULTS: Interleukin-6 was elevated (p < 0.001) immediately post-exercise compared to baseline in both conditions, but was lower in HCHO (p = 0.015).
  • Hepcidin levels were also lower at baseline (p = 0.049) in HCHO, and a large effect (d = 0.72) indicated a trend for lower levels at 3-h post-exercise compared to LCHO.
  • Serum iron was increased post-exercise for both trials (p = 0.001), whereas serum ferritin remained unchanged.
  • CONCLUSIONS: Twenty-four hours of controlled low carbohydrate intake resulted in higher baseline hepcidin levels and post-exercise IL-6 responses than a high carbohydrate intake.

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  • (PMID = 26335627.001).
  • [ISSN] 1439-6327
  • [Journal-full-title] European journal of applied physiology
  • [ISO-abbreviation] Eur. J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Dietary Carbohydrates; 0 / Hepcidins; 0 / Interleukin-6; 9007-73-2 / Ferritins; E1UOL152H7 / Iron
  • [Keywords] NOTNLM ; Athletes / Carbohydrates / Inflammation / Iron metabolism
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30. Aikemu A, Umar A, Yusup A, Upur H, Berké B, Bégaud B, Moore N: Immunomodulatory and antitumour effects of abnormal Savda Munziq on S180 tumour-bearing mice. BMC Complement Altern Med; 2012;12:157
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  • After the 14th day post tumour implant, thymus, liver, spleen and tumours were removed, weighed, and processed for histopathological analysis.

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  • (PMID = 22978453.001).
  • [ISSN] 1472-6882
  • [Journal-full-title] BMC complementary and alternative medicine
  • [ISO-abbreviation] BMC Complement Altern Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Cytokines; 0 / Drugs, Chinese Herbal; 0 / Immunologic Factors
  • [Other-IDs] NLM/ PMC3489790
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31. Vierhapper H, Heinze G, Gessl A, Exner M: Adrenocortical tumors: prevalence of impaired glucose tolerance and of "Paradoxical Rise" of cortisol during an oral glucose tolerance test. Exp Clin Endocrinol Diabetes; 2003 Oct;111(7):415-20
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  • Patients as well as controls with this abnormal behaviour of cortisol were characterized by lower basal serum cortisol concentrations (p < 0.01) but no association was seen with either the presence of IGT or with post-dexamethasone concentrations of serum cortisol.
  • Thus both in patients with and without adrenal incidentalomas abnormal glucose tolerance is an age- and weight-dependent phenomenon unrelated to the post-prandial behaviour of serum cortisol concentrations.

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  • (PMID = 14614648.001).
  • [ISSN] 0947-7349
  • [Journal-full-title] Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • [ISO-abbreviation] Exp. Clin. Endocrinol. Diabetes
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Glucocorticoids; 7S5I7G3JQL / Dexamethasone; IY9XDZ35W2 / Glucose; WI4X0X7BPJ / Hydrocortisone
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32. Introini-Collison IB, Dalmaz C, McGaugh JL: Amygdala beta-noradrenergic influences on memory storage involve cholinergic activation. Neurobiol Learn Mem; 1996 Jan;65(1):57-64
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  • The first experiment examined the effects of post-training systemic injections of the muscarinic agonist oxotremorine (100.0 micrograms/kg) administered alone or together with intraamygdala injections of either the muscarinic antagonist atropine (1.0 microgram) or the beta-noradrenergic antagonist propranolol (0.3 microgram).
  • In the second experiment intraamygdala infusions of the beta-noradrenergic agonist clenbuterol (10.0 ng) were administered either alone or together with atropine (1.0 microgram).
  • In the third experiment intraamygdala infusions of oxotremorine (3, 10, 30, or 100 ng) were administered either alone or together with propranolol (0.3 microgram).

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  • (PMID = 8673407.001).
  • [ISSN] 1074-7427
  • [Journal-full-title] Neurobiology of learning and memory
  • [ISO-abbreviation] Neurobiol Learn Mem
  • [Language] eng
  • [Grant] United States / NIMH NIH HHS / MH / MH 12526
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Cholinergic Antagonists; 0 / Muscarinic Antagonists; 5RY0UWH1JL / Oxotremorine; 7C0697DR9I / Atropine; 9Y8NXQ24VQ / Propranolol; N9YNS0M02X / Acetylcholine; XTZ6AXU7KN / Clenbuterol
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33. Li L, Lin CR, Ren JX, Miao L, Yao MJ, Li D, Shi Y, Ma YL, Fu JH, Liu JX: [Effect of formula of removing both phlegm and blood stasis in improving cardiac function of Chinese mini-swine with coronary heart disease of phlegm-stasis cementation syndrome]. Zhongguo Zhong Yao Za Zhi; 2014 Feb;39(3):483-7
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  • 5 g kg-1, with six in each group.
  • The ultrasonic cardiogram indicated notable decrease in IVSd, LVPWs, EF and FS, and remarkable increase in LVIDs (P<0. 05 orP<0.01).
  • The clinical cardiac function detection method could be adopted to correctly evaluate the changes in the post-myocardial ischemia cardiac function, and narrow the gap between clinical application and basic experimental studies.

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  • (PMID = 24946552.001).
  • [ISSN] 1001-5302
  • [Journal-full-title] Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  • [ISO-abbreviation] Zhongguo Zhong Yao Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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34. Sen CC, Yumusak N, Faundez R, Temamogullari F, Taskin A: Evaluation of intra-testicular injections of calcium chloride and 4-vinylcyclohexene 1,2 monoepoxide for chemical sterilization in guinea pigs. Pol J Vet Sci; 2017 Mar 01;20(2):251-260
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  • On day 90 post-administration, all animals were weighed and later decapitated under ether anaesthesia.

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  • (PMID = 28865222.001).
  • [ISSN] 1505-1773
  • [Journal-full-title] Polish journal of veterinary sciences
  • [ISO-abbreviation] Pol J Vet Sci
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / 4-vinylcyclohexene 1,2 monoepoxide; 0 / Adjuvants, Pharmaceutic; 0 / Cyclohexenes; 3XMK78S47O / Testosterone; 4TI98Z838E / Estradiol; 9002-62-4 / Prolactin; M4I0D6VV5M / Calcium Chloride
  • [Keywords] NOTNLM ; 4-vinylocyclohexene 1,2-monoepoxide / calcium chloride / chemical castration / guinea pig / sperm
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35. Costa de Andrade G, Wertheimer C, Eibl K, Wolf A, Kampik A, Buchele Rodrigues E, Farah ME, Haritoglou C: Viability of Primary Human Pigment Epithelium Cells and Muller-Glia Cells after Intravitreal Ziv-Aflibercept and Aflibercept. Ophthalmologica; 2016;236(4):223-227
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  • PURPOSE: The aim of this study was to access the safety profiles of 2 fusion proteins with anti-vascular endothelial growth factor action (ziv-aflibercept and aflibercept) on retinal pigment epithelium cells and Muller-Glia cells in culture by assessing cell viability post drug exposure.
  • RESULTS: Cell viability of both pRPE and Mio-M1 presented no significant changes after exposure of ziv-aflibercept and aflibercept.
  • Progressive NaCl concentrations did not significantly alter cell viability.
  • The exposure to the negative control of 75 µL/mL of dimethyl sulfoxide showed significant reduction in cell viability.
  • CONCLUSIONS: At clinical doses, neither ziv-aflibercept nor aflibercept caused any significant reduction in cell viability in vitro.
  • Furthermore, injection solutions of NaCl with higher osmolality caused no significant reduction in cell viability.
  • [MeSH-minor] Cadaver. Cell Survival / drug effects. Cells, Cultured. Dose-Response Relationship, Drug. Humans. Intravitreal Injections

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  • [Copyright] © 2017 S. Karger AG, Basel.
  • (PMID = 27997919.001).
  • [ISSN] 1423-0267
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Recombinant Fusion Proteins; 15C2VL427D / aflibercept; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor
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36. El-Ganzoury MM, El-Farrash RA, Saad AA, Mohamed AG, El-Sherbini IG: In vivo effect of recombinant human granulocyte colony-stimulating factor on neutrophilic expression of CD11b in septic neonates: a randomized controlled trial. Pediatr Hematol Oncol; 2012 Apr;29(3):272-84
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  • Granulocyte colony-stimulating factor (G-CSF) stimulates myeloid progenitor cell proliferation and induces selective neutrophil functions.
  • Total leukocytes count (TLC), absolute neutrophil count (ANC), and immature myeloid cell count in G-CSF group showed significant difference between post-and pre-G-CSF levels.
  • TLC, ANC, immature myeloid cell count and immature/total myeloid cells ratio were higher in G-CSF group compared to non-G-CSF group on days 1 and 3.
  • [MeSH-minor] Anti-Bacterial Agents / therapeutic use. Blood Cell Count. Cell Proliferation / drug effects. Hospitalization. Humans. Infant, Newborn. Treatment Outcome

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  • (PMID = 22475305.001).
  • [ISSN] 1521-0669
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antigens, CD11b; 0 / ITGAM protein, human; 143011-72-7 / Granulocyte Colony-Stimulating Factor
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37. Wakui S, Yokoo K, Takahashi H, Muto T, Suzuki Y, Kanai Y, Hano H, Furusato M, Endou H: Prenatal 3,3',4,4',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene. Toxicol Appl Pharmacol; 2006 Feb 1;210(3):200-11
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  • ) (i.g.) to 50-day-old female Sprague-Dawley rats whose dams had been treated (i.g.) with 2.5 ng, 250 ng, 7.5 microg of PCB126/kg or the vehicle on days 13 to 19 post-conception.
  • [MeSH-minor] Animals. Cytochrome P-450 CYP1B1. Dose-Response Relationship, Drug. Drug Synergism. Enzyme Induction. Female. Liver / metabolism. Liver / pathology. Maternal Exposure. Pregnancy. RNA, Messenger / biosynthesis. Rats. Rats, Sprague-Dawley. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 15990133.001).
  • [ISSN] 0041-008X
  • [Journal-full-title] Toxicology and applied pharmacology
  • [ISO-abbreviation] Toxicol. Appl. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens, Environmental; 0 / Environmental Pollutants; 0 / RNA, Messenger; 0 / Receptors, Aryl Hydrocarbon; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene; DFC2HB4I0K / Polychlorinated Biphenyls; EC 1.14.14.1 / Aryl Hydrocarbon Hydroxylases; EC 1.14.14.1 / Cyp1b1 protein, rat; EC 1.14.14.1 / Cytochrome P-450 CYP1A1; EC 1.14.14.1 / Cytochrome P-450 CYP1B1; TSH69IA9XF / 3,4,5,3',4'-pentachlorobiphenyl
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38. Fekete K, Boutou AK, Pitsiou G, Chavouzis N, Pataka A, Athanasiou I, Ilonidis G, Kontakiotis T, Argyropoulou P, Kioumis I: Resting energy expenditure in OSAS: the impact of a single CPAP application. Sleep Breath; 2016 Mar;20(1):121-8
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  • REE/lean body mass (LBM) was higher among patients compared to controls both pre- (29.6 ± 12 vs 22.9 ± 7.9 kcal/kg; p = 0.022, correspondingly) and post-sleep (26.4 ± 9.6 vs 21.6 ± 9 kcal/kg; p = 0.047 correspondingly).
  • A single nasal CPAP application diminished the pre-post REE/LBM difference (30.3 ± 8.2 vs 28.3 ± 10.3 kcal/kg; p = 0.265), but only among responders.

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  • (PMID = 25971739.001).
  • [ISSN] 1522-1709
  • [Journal-full-title] Sleep & breathing = Schlaf & Atmung
  • [ISO-abbreviation] Sleep Breath
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] S88TT14065 / Oxygen
  • [Keywords] NOTNLM ; Continuous positive airway pressure / Desaturation / Nested case-control study / Obstructive sleep apnea syndrome / Resting energy expenditure
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39. Kokare DM, Patole AM, Carta A, Chopde CT, Subhedar NK: GABA(A) receptors mediate orexin-A induced stimulation of food intake. Neuropharmacology; 2006 Jan;50(1):16-24
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  • Cumulative food intake was measured during light phase of light/dark cycle at 1-, 2-, 4- and 6-h post-injection time points.

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  • (PMID = 16168444.001).
  • [ISSN] 0028-3908
  • [Journal-full-title] Neuropharmacology
  • [ISO-abbreviation] Neuropharmacology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / GABA Agonists; 0 / GABA Antagonists; 0 / GABA Modulators; 0 / GABA-A Receptor Antagonists; 0 / Intracellular Signaling Peptides and Proteins; 0 / Neuropeptides; 0 / Orexin Receptors; 0 / Orexins; 0 / Receptors, G-Protein-Coupled; 0 / Receptors, GABA-A; 0 / Receptors, Neuropeptide; 2763-96-4 / Muscimol; 40P7XK9392 / Flumazenil; Q3JTX2Q7TU / Diazepam
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40. Atchison E, Eklund J, Martone B, Wang L, Gidron A, Macvicar G, Rademaker A, Goolsby C, Marszalek L, Kozlowski J, Smith N, Kuzel TM: A pilot study of denileukin diftitox (DD) in combination with high-dose interleukin-2 (IL-2) for patients with metastatic renal cell carcinoma (RCC). J Immunother; 2010 Sep;33(7):716-22
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  • [Title] A pilot study of denileukin diftitox (DD) in combination with high-dose interleukin-2 (IL-2) for patients with metastatic renal cell carcinoma (RCC).
  • High-dose (HD) IL-2 is approved to treat renal cell carcinoma (RCC) with modest response rates and significant toxicity.
  • Enhancement of cytotoxic T-cell activity by IL-2 is 1 mechanism of action.
  • DD depletes IL-2 receptor (CD25 component) expressing cells.
  • For group B/C patients receiving DD, the median decline in Tregs was 56.3% from pre-DD to post-DD (P=0.013).
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols. Carcinoma, Renal Cell / therapy. Kidney Neoplasms / therapy. T-Lymphocytes, Cytotoxic / metabolism. T-Lymphocytes, Regulatory / metabolism
  • [MeSH-minor] Cell Count. Cell Proliferation / drug effects. Cell Separation. Diphtheria Toxin / administration & dosage. Diphtheria Toxin / adverse effects. Female. Flow Cytometry. Humans. Interleukin-2 / administration & dosage. Interleukin-2 / adverse effects. Interleukin-2 Receptor alpha Subunit / biosynthesis. Lymphocyte Depletion. Male. Middle Aged. Neoplasm Metastasis. Recombinant Fusion Proteins / administration & dosage. Recombinant Fusion Proteins / adverse effects

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  • (PMID = 20664355.001).
  • [ISSN] 1537-4513
  • [Journal-full-title] Journal of immunotherapy (Hagerstown, Md. : 1997)
  • [ISO-abbreviation] J. Immunother.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Diphtheria Toxin; 0 / Interleukin-2; 0 / Interleukin-2 Receptor alpha Subunit; 0 / Recombinant Fusion Proteins; 25E79B5CTM / denileukin diftitox
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41. Unger LW, Herac M, Staufer K, Salat A, Silberhumer G, Hofmann M, Trauner M, Rasoul-Rockenschaub S, Soliman T, Reiberger T, Berlakovich GA: The post-transplant course of patients undergoing liver transplantation for nonalcoholic steatohepatitis versus cryptogenic cirrhosis: a retrospective case-control study. Eur J Gastroenterol Hepatol; 2017 Mar;29(3):309-316
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  • [Title] The post-transplant course of patients undergoing liver transplantation for nonalcoholic steatohepatitis versus cryptogenic cirrhosis: a retrospective case-control study.
  • Although post-OLT plasma lipid levels and incidence of de-novo hypertension, diabetes, and hyperlipidemia were similar between groups, the post-transplant NFS re-increased in the NASH group (but not in the CC: -0.1317 vs. -1.3645 at 12 months post-OLT, P=0.0400).
  • Post-transplant survival was similar in NASH and CC patients.


42. Di Bartolomeo P, Di Girolamo G, Angrilli F, Schettini F, De Mattia D, Manzionna MM, Dragani A, Iacone A, Torlontano G: Reconstitution of normal neutrophil function in chronic granulomatous disease by bone marrow transplantation. Bone Marrow Transplant; 1989 Nov;4(6):695-700
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  • No episode of infection occurred in the post-transplant course and, currently, 40 months after transplantation the patient is in excellent health and growing normally and showing an increasing improvement of his respiratory capacity.


43. Du D, Gao B, Xin G, Sun A, Huang B, Zhang R, Xing Z, Chen Q, He Y, Huang W: Determination of deltonin in rat plasma by using HPLC-MS/MS and the application of this method in pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Jul 15;931:1-5
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  • Deltonin was found to be stable under short-term temperature conditions, post-preparative temperature conditions, and after 3 freeze-thaw cycles conditions.

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  • [Copyright] Copyright © 2013 Elsevier B.V. All rights reserved.
  • (PMID = 23747424.001).
  • [ISSN] 1873-376X
  • [Journal-full-title] Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
  • [ISO-abbreviation] J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Spirostans; 55659-75-1 / deltonin
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44. Wihastuti TA, Heriansyah T: The inhibitory effects of polysaccharide peptides (PsP) of &lt;i&gt;Ganoderma lucidum&lt;/i&gt; against atherosclerosis in rats with dyslipidemia. Heart Int; 2017 Jan-Dec;12(1):e1-e7
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  • Materials and methods: The study was an experimental in vivo post-test with control group design.

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  • (PMID = 29114382.001).
  • [ISSN] 1826-1868
  • [Journal-full-title] Heart international
  • [ISO-abbreviation] Heart Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Keywords] NOTNLM ; Atherogenesis / Dyslipidemia / EPC / PsP
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45. Jun JH, Jun NH, Shim JK, Shin EJ, Kwak YL: Erythropoietin protects myocardium against ischemia-reperfusion injury under moderate hyperglycemia. Eur J Pharmacol; 2014 Dec 15;745:1-9
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  • It also enhanced ERK induced GATA-4 post-translational modifications such as increased GATA-4 phosphorylation and acetylation, and decreased GATA-4 ubiquitination following hypoxia-reoxygenation in H9c2 cells in hyperglycemic medium.
  • [MeSH-minor] Acetylation. Animals. Apoptosis. Cardiotonic Agents / administration & dosage. Cardiotonic Agents / metabolism. Caspase 3 / metabolism. Cell Line. GATA4 Transcription Factor / metabolism. MAP Kinase Signaling System / drug effects. Male. Myocytes, Cardiac / drug effects. Myocytes, Cardiac / metabolism. Myocytes, Cardiac / pathology. Phosphorylation. Proto-Oncogene Proteins c-bcl-2 / metabolism. Rats. Rats, Sprague-Dawley. Ubiquitination

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  • [Copyright] Copyright © 2014 Elsevier B.V. All rights reserved.
  • (PMID = 25446919.001).
  • [ISSN] 1879-0712
  • [Journal-full-title] European journal of pharmacology
  • [ISO-abbreviation] Eur. J. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cardiotonic Agents; 0 / GATA4 Transcription Factor; 0 / Gata4 protein, rat; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / erythropoietin, rat; 11096-26-7 / Erythropoietin; EC 3.4.22.- / Casp3 protein, rat; EC 3.4.22.- / Caspase 3
  • [Keywords] NOTNLM ; Bcl-2 / Cardioprotection / Caspase-3 / Erythropoietin / GATA binding protein-4 / Hyperglycemia
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46. Patchen ML: Amifostine plus granulocyte colony-stimulating factor therapy enhances recovery from supralethal radiation exposures: preclinical experience in animals models. Eur J Cancer; 1995;31A Suppl 1:S17-21
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  • 30 min before 60Co irradiation and/or 125 micrograms/kg G-CSF subcutaneously from days 1-16 post irradiation were compared.

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  • (PMID = 7577095.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Radiation-Protective Agents; 0 / Recombinant Proteins; 143011-72-7 / Granulocyte Colony-Stimulating Factor; M487QF2F4V / Amifostine
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47. Wood WG, Armbrecht HJ: Age differences in ethanol-induced hypothermia and impairment in mice. Neurobiol Aging; 1982;3(3):243-6
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  • Body temperature also was measured prior to injection and at 30 and 120 min post-injection The aged mice showed less ethanol-induced hypothermia but were impaired longer as compared to the younger mice.

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  • (PMID = 7162553.001).
  • [ISSN] 0197-4580
  • [Journal-full-title] Neurobiology of aging
  • [ISO-abbreviation] Neurobiol. Aging
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 3K9958V90M / Ethanol
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48. Altena TS, Michaelson JL, Ball SD, Thomas TR: Single sessions of intermittent and continuous exercise and postprandial lipemia. Med Sci Sports Exerc; 2004 Aug;36(8):1364-71
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  • After 48-h activity and 24-h dietary control periods, subjects consumed a high-fat meal (HFM) containing 1.5 g fat (88% of calories), 0.05 g protein, and 0.4 g carbohydrate per kilogram body weight for three trials: no exercise (NOEX), CON-EX, and INT-EX.
  • Blood was collected before the HFM (0 h) and at 2, 4, 6, and 8 h post-HFM.

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  • (PMID = 15292745.001).
  • [ISSN] 0195-9131
  • [Journal-full-title] Medicine and science in sports and exercise
  • [ISO-abbreviation] Med Sci Sports Exerc
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cholesterol, HDL; 0 / Triglycerides
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49. Collombet JM, Mourcin F, Grenier N, Four E, Masqueliez C, Baubichon D, Lallement G, Hérodin F: Effect of soman poisoning on populations of bone marrow and peripheral blood cells in mice. Neurotoxicology; 2005 Jan;26(1):89-98
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  • According to recent reports, brain lesions resulting from ischemia, mechanical injury or neurodegenerative diseases can be partially treated using bone marrow-derived stromal cell (BMSC) engraftment approaches.
  • Various parameters were determined such as PB cell counting or, for BM samples, myelogram, in vitro colony-forming cells and phenotypic flow cytometry analysis.
  • On post-soman day 1, a significant decrease in numbers of white blood cells and an increase in erythrocyte and platelet counts were noted.
  • On post-soman day 4, the number of HPC decreased significantly, probably due to reduction of the replication rate of these immature cells.
  • On post-soman day 8 and day 22, the number of monocytes and granulocytes in the blood had considerably increased, probably due to a strong inflammatory reaction in response to soman poisoning.
  • In conclusion, PB cell and BM-derived HPC populations are affected by acute soman poisoning, suggesting particular care, mainly for graft kinetic aspects, during future development of autologous BM stem cell therapy strategy to treat nerve agent-induced brain damage.
  • [MeSH-minor] Animals. Blood Cell Count. Bromodeoxyuridine. Cell Cycle / drug effects. Cell Division / drug effects. Cell Lineage / drug effects. Colony-Forming Units Assay. Flow Cytometry. Male. Mice. Myelography. Stem Cells / drug effects. Time Factors

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  • (PMID = 15527876.001).
  • [ISSN] 0161-813X
  • [Journal-full-title] Neurotoxicology
  • [ISO-abbreviation] Neurotoxicology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Chemical Warfare Agents; 96-64-0 / Soman; G34N38R2N1 / Bromodeoxyuridine
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50. Shih CC, Lin CH, Lin WL: Ameliorative effects of Vaccaria segetalis extract on osteopenia in ovariectomized rats. J Nat Med; 2009 Oct;63(4):386-92
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  • At 6 weeks post-OVX, the OVX rats were divided into four groups treated with water, 17beta-estradiol (30 microg/kg, daily subcutaneous injection), or VSE (0.5 or 1.0 g/kg, daily, orally) for 6 weeks.

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  • (PMID = 19475478.001).
  • [ISSN] 1861-0293
  • [Journal-full-title] Journal of natural medicines
  • [ISO-abbreviation] J Nat Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Plant Extracts; 4TI98Z838E / Estradiol; 97C5T2UQ7J / Cholesterol; EC 3.1.3.1 / Alkaline Phosphatase; SY7Q814VUP / Calcium
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51. Staatz G, Nolte-Ernsting CC, Bücker A, Misselwitz B, Grosskortenhaus S, Pflüger D, Günther RW: [Interstitial T1-weighted MR lymphography with use of the dendritic contrast agent Gadomer-17 in pigs]. Rofo; 2001 Dec;173(12):1131-6
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  • The enhancement of the lymphatic system decreased slowly until 150 minutes post injection.

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  • (PMID = 11740675.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; 0 / gadomer 17; AU0V1LM3JT / Gadolinium
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52. Bourget P, Dechelette N, Fernandez H, Desmaris VQ: Disposition of ornidazole and its metabolites during pregnancy. J Antimicrob Chemother; 1995 May;35(5):691-6
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  • Trough concentrations of ornidazole measured at 24 h post dose were above the MIC of sensitive organisms.

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  • (PMID = 7592184.001).
  • [ISSN] 0305-7453
  • [Journal-full-title] The Journal of antimicrobial chemotherapy
  • [ISO-abbreviation] J. Antimicrob. Chemother.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 62580-79-4 / alpha-(chloromethyl)-2-hydroxymethyl-5-nitroimidazole-1-ethanol; 62580-80-7 / 3-(2-methyl-5-nitroimidazole-1-yl)-1,2-propanediol; 62XCK0G93T / Ornidazole; 75J73V1629 / Ceftriaxone; VZ8RRZ51VK / Tobramycin
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53. Fan GC, Rong XZ, Wang XM, Liu SR, Zhou YP, Li QH: [Influence of exogenous putrescine and cadaverine on pro-inflammatory factors in the peripheral blood of rabbits]. Zhonghua Shao Shang Za Zhi; 2012 Dec;28(6):451-4
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  • The blood sample in the volume of 2 mL was collected from the central artery of rabbit ears before injection and at 2, 6, 12, 24, 30, 36, 48, 60 hours post injection (PIH).
  • (1) The serum contents of TNF-α, IL-1, and IL-6 were increased in NTH, putrescine, and cadaverine groups in different degrees at most post injection time points.
  • There was no significant change in the concentrations of the three pro-inflammatory factors in saline group, and they were significantly lower than those of the other three groups at most post injection time points (with F values from 3.49 to 13.58, P values all below 0.05).

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  • (PMID = 23327914.001).
  • [ISSN] 1009-2587
  • [Journal-full-title] Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
  • [ISO-abbreviation] Zhonghua Shao Shang Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Interleukin-1; 0 / Interleukin-6; 0 / Tumor Necrosis Factor-alpha; L90BEN6OLL / Cadaverine; V10TVZ52E4 / Putrescine
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54. Ding Z, Han M, Chen S, Ma Q, Wei J, Pang A, Huang Y, Zhang X, Liang C, Liu X, Yao J, Li G, Cao Y, Feng S, Jiang E: [Outcomes of adults with Ph-negative B-cell acute lymphoblastic leukemia after autologous hematopoietic stem cell transplantation and the significance of minimal residual disease]. Zhonghua Xue Ye Xue Za Zhi; 2015 Jul;36(7):587-92
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  • [Title] [Outcomes of adults with Ph-negative B-cell acute lymphoblastic leukemia after autologous hematopoietic stem cell transplantation and the significance of minimal residual disease].
  • OBJECTIVE: To better understand predictive factors and role of autologous hematopoietic stem cell transplantation (auto-HSCT)in the post-remission therapy for adult Ph-negative B-cell acute lymphoblastic leukemia (B-ALL)patients.
  • For DFS, age ≥ 35 years, high lactate dehydrogenase at diagnosis, high initial WBC count, blast cell proportion ≥ 5% on 15th day of the first induction therapy, complete remession (CR)1 to HSCT interval >6 months and CD34⁺ cells in graft ≥ 3.8 × 10⁶/kg were the poor prognostic factors.
  • For 34 patients who had results of minimal residual disease (MRD), positive pretransplantation MRD (MRD≥0.01%), positive post-induction MRD or MRD positive again during the chemotherapy indicated poor prognosis, and the last one was the independent adverse prognostic factor.
  • CONCLUSION: Auto-HSCT combined with post-transplantation maintenance chemotherapy could be an optional approach for adult B-ALL patients.
  • [MeSH-major] Hematopoietic Stem Cell Transplantation. Neoplasm, Residual. Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy

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  • (PMID = 26304084.001).
  • [ISSN] 0253-2727
  • [Journal-full-title] Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
  • [ISO-abbreviation] Zhonghua Xue Ye Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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55. Miguez AC, Francisco JC, Barberato SH, Simeoni R, Précoma D, do Amaral VF, Rodrigues E, Olandoski M, de Noronha L, Greca FH, de Carvalho KA, Faria-Neto JR, Guarita-Souza LC: The functional effect of soybean extract and isolated isoflavone on myocardial infarction and ventricular dysfunction: the soybean extract on myocardial infarction. J Nutr Biochem; 2012 Dec;23(12):1740-8
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  • OBJECTIVE: The objective was to analyze the functional and anatomopathological post-myocardial-infarction effects of soybean extract (SE) and isoflavone (IF).

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  • [Copyright] Copyright © 2012 Elsevier Inc. All rights reserved.
  • (PMID = 22717376.001).
  • [ISSN] 1873-4847
  • [Journal-full-title] The Journal of nutritional biochemistry
  • [ISO-abbreviation] J. Nutr. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Isoflavones; 0 / Plant Extracts; 9007-34-5 / Collagen; EC 1.1.1.27 / L-Lactate Dehydrogenase
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56. Ballard KD, Kupchak BR, Volk BM, Mah E, Shkreta A, Liptak C, Ptolemy AS, Kellogg MS, Bruno RS, Seip RL, Maresh CM, Kraemer WJ, Volek JS: Acute effects of ingestion of a novel whey-derived extract on vascular endothelial function in overweight, middle-aged men and women. Br J Nutr; 2013 Mar 14;109(5):882-93
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  • Acute NOP-47 ingestion increased FMD at 30 min (4·6 (sem 0·5) %) and 120 min (5·1 (sem 0·5) %) post-ingestion (P< 0·05, time × trial interaction), and FMD responses at 120 min were significantly greater in the NOP-47 trial compared with placebo (4·3 (sem 0·5) %).

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  • (PMID = 22691263.001).
  • [ISSN] 1475-2662
  • [Journal-full-title] The British journal of nutrition
  • [ISO-abbreviation] Br. J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Amino Acids; 0 / Insulin; 0 / Milk Proteins; 0 / Placebos; 0 / Protein Hydrolysates; 0 / Whey Proteins
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57. Gokahmetoglu G, Aksu R, Bicer C, Darcin K, Ugur F: The effect of levosimendan combined with 20% lipid emulsion treatment on survival from bupivacaine induced toxicity in experiment. Bratisl Lek Listy; 2014;115(5):275-9
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  • BACKGROUND: Recent reports demonstrated that levosimendan improved post-resuscitation myocardial function in rat and pig models.

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  • (PMID = 24836408.001).
  • [ISSN] 0006-9248
  • [Journal-full-title] Bratislavské lekárske listy
  • [ISO-abbreviation] Bratisl Lek Listy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Fat Emulsions, Intravenous; 0 / Hydrazones; 0 / Pyridazines; 349552KRHK / simendan; Y8335394RO / Bupivacaine
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58. Yuan T, He J, Xie M, Huo S, Wang Q: [Effects of 7.5% hypertonic saline pre-injection on postoperative cognitive dysfunction in senile rats]. Zhonghua Yi Xue Za Zhi; 2015 Jan 20;95(3):217-20
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  • Escape latency and frequency of crossing original platform were assessed by Morris water maze on 1 day pre-operation and 1, 3, 7 days post-operation.
  • And ultrastructures of hippocampal neurons were observed with transmission electron microscope at 1 day pre-operation and 1, 7 days post-operation.
  • RESULTS: Compared with pre-dosing value, escape latency was significantly prolonged, the frequency of crossing original platform decreased and apoptotic rate and [Ca²⁺]i increased at each time point post-operation in groups M and HS.
  • Compared with group M, escape latency was significantly shortened, the frequency of crossing original platform increased and apoptotic rate and [Ca²⁺]i decreased at each time point post-operation in group HS.

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  • (PMID = 25877035.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Saline Solution, Hypertonic
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59. Vena AA, Gonzales RA: Temporal profiles dissociate regional extracellular ethanol versus dopamine concentrations. ACS Chem Neurosci; 2015 Jan 21;6(1):37-47
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  • Post hoc analyses examined ratios of the dopamine response (represented as a percent above baseline) to tissue concentrations of ethanol at different time points within the first 25-30 min in the prefrontal cortex, NAc core and shell, and dorsomedial striatum following a single intravenous infusion of ethanol (1 g/kg).

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  • (PMID = 25537116.001).
  • [ISSN] 1948-7193
  • [Journal-full-title] ACS chemical neuroscience
  • [ISO-abbreviation] ACS Chem Neurosci
  • [Language] ENG
  • [Grant] United States / NIAAA NIH HHS / AA / R37 AA011852; United States / NIAAA NIH HHS / AA / T32 AA007471; United States / NIAAA NIH HHS / AA / T32 AA07471
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 3K9958V90M / Ethanol; VTD58H1Z2X / Dopamine
  • [Other-IDs] NLM/ PMC4304481
  • [Keywords] NOTNLM ; Dopamine / ethanol / microdialysis / prefrontal cortex / striatum
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60. Ottani A, Giuliani D, Ferrari F: Modulatory activity of sildenafil on copulatory behaviour of both intact and castrated male rats. Pharmacol Biochem Behav; 2002 Jun;72(3):717-22
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  • The data obtained show that sildenafil modifies both sexual arousal and the ejaculatory mechanisms of copulation, diminishing ejaculation latency in both categories and increasing copulatory efficacy in SE rats; in addition, it reduced the inter-intromission interval in both SE and NE animals and the post-ejaculatory interval only in SE animals.

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  • (PMID = 12175469.001).
  • [ISSN] 0091-3057
  • [Journal-full-title] Pharmacology, biochemistry, and behavior
  • [ISO-abbreviation] Pharmacol. Biochem. Behav.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Piperazines; 0 / Purines; 0 / Sulfones; BW9B0ZE037 / Sildenafil Citrate
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61. Dalmaz C, Godoy MG, Izquierdo I: Post-training and pretest effects of adrenocorticotropin on retention: the influence of the hour of the day, the training-test interval, and pretest naloxone administration. Behav Neural Biol; 1988 May;49(3):406-11
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  • [Title] Post-training and pretest effects of adrenocorticotropin on retention: the influence of the hour of the day, the training-test interval, and pretest naloxone administration.
  • Rats received an ip injection of 0.2 microgram/kg of ACTH-(1-39) 1 min after step-down inhibitory avoidance training and/or 5 min prior to retention testing.
  • Post-training ACTH induced memory facilitation in the morning and amnesia in the afternoon at both training-test intervals.
  • In addition, pretest ACTH induced a naloxone-reversible memory enhancement, both on its own and in animals treated with a facilitatory post-training dose of ACTH in the morning; this effect was seen only at the 24-h training-test interval.

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  • (PMID = 2841920.001).
  • [ISSN] 0163-1047
  • [Journal-full-title] Behavioral and neural biology
  • [ISO-abbreviation] Behav. Neural Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 36B82AMQ7N / Naloxone; 9002-60-2 / Adrenocorticotropic Hormone
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62. Rosenthal MA, Grigg AP, Sheridan WP: High dose busulphan/cyclophosphamide for autologous bone marrow transplantation is associated with minimal non-hemopoietic toxicity. Leuk Lymphoma; 1994 Jul;14(3-4):279-83
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  • Twenty-four patients received bone marrow (BM) alone, 22 received BM plus post-transplant granulocyte-colony stimulating factor (G-CSF) and 23 received peripheral blood progenitor cells (PBPC) +/- BM plus post-transplant G-CSF.
  • Post-transplant G-CSF (+/- PBPC) resulted in a trend (p = 0.07) towards a reduction in post-transplant stomatitis, but did not impact on the already low incidence of other organ toxicities.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Bone Marrow Transplantation. Hodgkin Disease / drug therapy. Hodgkin Disease / therapy. Leukemia, Myeloid / drug therapy. Leukemia, Myeloid / therapy. Lymphoma, Non-Hodgkin / drug therapy. Lymphoma, Non-Hodgkin / therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • [MeSH-minor] Acute Disease. Administration, Oral. Adolescent. Adult. Busulfan / administration & dosage. Busulfan / adverse effects. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Cyclophosphamide / adverse effects. Dose-Response Relationship, Drug. Drug Administration Schedule. Female. Granulocyte Colony-Stimulating Factor / adverse effects. Granulocyte Colony-Stimulating Factor / therapeutic use. Hematopoietic Stem Cell Transplantation. Humans. Male. Middle Aged. Retrospective Studies. Stomatitis / chemically induced. Survival Analysis

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  • (PMID = 7524888.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; Journal Article
  • [Publication-country] SWITZERLAND
  • [Chemical-registry-number] 143011-72-7 / Granulocyte Colony-Stimulating Factor; 8N3DW7272P / Cyclophosphamide; G1LN9045DK / Busulfan
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63. Dewan ZF, Morris ID, Lendon RG: Administration of exogenous testosterone in the adult rat and its effects on reproductive organs, sex hormones and body-weight. Bangladesh Med Res Counc Bull; 2000 Aug;26(2):48-55
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  • The testicular testosterone (TT) content remained significantly lower (p < 0.05) from the 6th to the 36th days post-injection.

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  • (PMID = 11508071.001).
  • [ISSN] 0377-9238
  • [Journal-full-title] Bangladesh Medical Research Council bulletin
  • [ISO-abbreviation] Bangladesh Med Res Counc Bull
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Bangladesh
  • [Chemical-registry-number] 0 / Gonadal Steroid Hormones; 3XMK78S47O / Testosterone
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64. Ray SD, Jena N: A hepatotoxic dose of acetaminophen modulates expression of BCL-2, BCL-X(L), and BCL-X(S) during apoptotic and necrotic death of mouse liver cells in vivo. Arch Toxicol; 2000 Jan;73(10-11):594-606
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  • This study demonstrates that administration of a hepatotoxic dose of AAP to ICR mice results in severe liver injury (ALT leakage >200-fold at 6 h and >600-fold at 18 h) leading to massive cell death by apoptosis (diagnosed by nuclear ultrastructure, histopathology, and DNA ladder), in addition to necrosis coupled with spectacular changes in the BCL-X(L) expression (6 and 18 h after AAP administration).
  • As the toxicity progressed, during 6 and 18 h post-AAP administration, the BCL-X(L) protein band shifted to a slower mobility band which might represent a phosphorylated form of BCL-X(L).
  • [MeSH-minor] Alanine Transaminase / blood. Animals. Blotting, Western. Cell Nucleus / drug effects. Cell Nucleus / ultrastructure. Cytoplasm / drug effects. Cytoplasm / ultrastructure. DNA / analysis. DNA Fragmentation. Gene Expression Regulation. Male. Mice. Mice, Inbred ICR. Necrosis. Phosphorylation. bcl-X Protein

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  • [ErratumIn] Arch Toxicol 2000 Mar;74(1):60
  • (PMID = 10663392.001).
  • [ISSN] 0340-5761
  • [Journal-full-title] Archives of toxicology
  • [ISO-abbreviation] Arch. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] GERMANY
  • [Chemical-registry-number] 0 / Bcl2l1 protein, mouse; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / bcl-X Protein; 362O9ITL9D / Acetaminophen; 9007-49-2 / DNA; EC 2.6.1.2 / Alanine Transaminase
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65. Makino M, Lodato RF, Stephens LC, Strebel FR, Jenkins G, Ohno S, Sakaguchi Y, Kostergaard J, Tomasovic SP, Bull JM: Protective effect of NG-monomethyl-L-arginine against hypotension inducted by combined tumour necrosis factor-alpha and whole body hyperthermia in rats. Int J Hyperthermia; 1996 Sep-Oct;12(5):617-34
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  • This increase in MAP was sustained throughout the hyperthermia, but was followed by a transient relative hypotension (MAP = 80 +/- mm Hg) on cessation of WBH and an eventual return to near baseline at 30 min post-WBH (MAP = 94 +/- 5 mm Hg).
  • This late hypotensive state was associated with a mortality during the early (first 2 h) post-WBH period of 17 and 100% at TNF dose of 10(5) and 10(6) U/kg TNF, respectively.
  • L-NMA prevented the post-WBH hypotension, and extended the survival beyond the early (first 2 h) post-WBH period.
  • WBH + TNF (10(5) and 10(6) U/kg) also produced marked histopathological injury to the gut mucosa at 2 h post-treatment.

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  • (PMID = 8886889.001).
  • [ISSN] 0265-6736
  • [Journal-full-title] International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • [ISO-abbreviation] Int J Hyperthermia
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01-CA43090
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Tumor Necrosis Factor-alpha; 27JT06E6GR / omega-N-Methylarginine; 31C4KY9ESH / Nitric Oxide; BG3F62OND5 / Carboplatin; EC 1.14.13.39 / Nitric Oxide Synthase
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66. Matte JJ, Guilbault LA, Dubreuil P, Petitclerc D, Pelletier G: Plasma lactose after weaning and its relationship with lactose content of milk, post-weaning plasma oestradiol-17 beta and weaning to mating interval in sows. Reprod Nutr Dev; 1989;29(1):75-82
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  • [Title] Plasma lactose after weaning and its relationship with lactose content of milk, post-weaning plasma oestradiol-17 beta and weaning to mating interval in sows.
  • Twenty first-liter sows were used to investigate the relationship between plasma lactose concentrations following weaning and milk production, total milk content of lactose, post-weaning plasma oestradiol-17beta (E2) concentration and weaning to mating interval.
  • Plasma lactose concentrations (means +/- SE) after weaning increased from 52 +/- 4 microM at the beginning of sampling to a peak value of 183 +/- 23 microM 40 h later and then decreased to 91 +/- 11 microM 66 h after weaning (P less than 0.001).
  • On a within-sow basis, there was a correlation (r = 0.28; P less than 0.01) between post-weaning plasma lactose and E2 concentrations.
  • Results showed the existence of the post-weaning peak of plasma lactose in sows.(ABSTRACT TRUNCATED AT 250 WORDS)

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  • (PMID = 2928602.001).
  • [ISSN] 0181-1916
  • [Journal-full-title] Reproduction, nutrition, développement
  • [ISO-abbreviation] Reprod Nutr Dev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] FRANCE
  • [Chemical-registry-number] 4TI98Z838E / Estradiol; J2B2A4N98G / Lactose
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67. Bacal F, Pires PV, Moreira LF, Silva CP, Filho JR, Costa UM, Rosário-Neto MA, Avila VM, Cruz FD, Guimarães GV, Issa VS, Ferreira SA, Stolf N, Ramires JA, Bocchi E: Normalization of right ventricular performance and remodeling evaluated by magnetic resonance imaging at late follow-up of heart transplantation: relationship between function, exercise capacity and pulmonary vascular resistance. J Heart Lung Transplant; 2005 Dec;24(12):2031-6
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  • We then compared Group 1 with a control group consisting of 10 patients, who were < or =1 year post-HT (Group 2), hemodynamically stable, and with the same pre-operative hemodynamic features as Group 1.

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  • (PMID = 16364845.001).
  • [ISSN] 1557-3117
  • [Journal-full-title] The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
  • [ISO-abbreviation] J. Heart Lung Transplant.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Cirulli F, Laviola G: Paradoxical effects of D-amphetamine in infant and adolescent mice: role of gender and environmental risk factors. Neurosci Biobehav Rev; 2000 Jan;24(1):73-84
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  • These effects appear much larger at both post weaning stages than in preweanlings and are significantly more pronounced in females than in males.

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  • (PMID = 10654663.001).
  • [ISSN] 0149-7634
  • [Journal-full-title] Neuroscience and biobehavioral reviews
  • [ISO-abbreviation] Neurosci Biobehav Rev
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Central Nervous System Stimulants; TZ47U051FI / Dextroamphetamine
  • [Number-of-references] 107
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69. Miyazaki Y, Mahankali A, Matsuda M, Mahankali S, Hardies J, Cusi K, Mandarino LJ, DeFronzo RA: Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab; 2002 Jun;87(6):2784-91
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  • After 16 wk of pioglitazone treatment, fasting plasma glucose (179 +/- 10 to 140 +/- 10 mg/dl; P < 0.01), mean plasma glucose during OGTT (295 +/- 13 to 233 +/- 14 mg/dl; P < 0.01), and hemoglobin A(1c) (8.6 +/- 0.4% to 7.2 +/- 0.5%; P < 0.01) decreased without a change in fasting or post-OGTT insulin levels.

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  • (PMID = 12050251.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK 24092; United States / NCRR NIH HHS / RR / M01 RR 01346
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Hypoglycemic Agents; 0 / Insulin; 0 / Thiazoles; 0 / Thiazolidinediones; IY9XDZ35W2 / Glucose; X4OV71U42S / pioglitazone
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70. Lora-Michiels M, Anzola K, Amaya G, Solano M: Quantitative and qualitative scintigraphic measurement of renal function in dogs exposed to toxic doses of Gentamicin. Vet Radiol Ultrasound; 2001 Nov-Dec;42(6):553-61
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  • Baseline and post-gentamicin injection blood urea nitrogen (BUN) and serum creatinine values were determined.
  • [MeSH-minor] Animals. Dogs. Dose-Response Relationship, Drug. Female. Kidney Function Tests / veterinary. Male. Predictive Value of Tests. Technetium Tc 99m Dimercaptosuccinic Acid. Technetium Tc 99m Mertiatide. Technetium Tc 99m Pentetate

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  • (PMID = 11768525.001).
  • [ISSN] 1058-8183
  • [Journal-full-title] Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
  • [ISO-abbreviation] Vet Radiol Ultrasound
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Gentamicins; 0 / Radiopharmaceuticals; 36ITO9SKQJ / Technetium Tc 99m Mertiatide; 494JNQ8L28 / Technetium Tc 99m Dimercaptosuccinic Acid; VW78417PU1 / Technetium Tc 99m Pentetate
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71. Restrepo A, Albrecht F, Raez LE, Fernandez HF, Nassiri M, Byrne G Jr, Cassileth PA: Post-liver transplantation lymphoproliferative disorders with and without infusions of donor bone marrow cells. Crit Rev Oncog; 1999;10(3):239-45
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  • [Title] Post-liver transplantation lymphoproliferative disorders with and without infusions of donor bone marrow cells.
  • Donor bone marrow cells (DBMC) infusions have been used in an attempt to decrease the untoward effects of immunosuppressive treatment and to improve immunocompetence in the post-liver transplantation (PLT) period.
  • All lymphomas were non-Hodgkin's B-cell type, three diffuse large cell lymphoma, and one mixed cell lymphoma.


72. Rother E, Cornel P: Potentials and limits of a pre-denitrification/ nitrification biofilter configuration for advanced municipal wastewater treatment. Water Sci Technol; 2007;55(8-9):115-23
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  • The combination of pre-DN, N and post-DN filters is much more advisable for most municipal wastewaters, because the recycle rate can be reduced and external carbon can be saved.

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  • (PMID = 17546977.001).
  • [ISSN] 0273-1223
  • [Journal-full-title] Water science and technology : a journal of the International Association on Water Pollution Research
  • [ISO-abbreviation] Water Sci. Technol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Nitrates; 0 / Water Pollutants, Chemical; N762921K75 / Nitrogen
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73. Witten ML, Lantz RC, Grad R, Seidner S, Hubbard AK, Quan SF, Lemen RJ: Effect of smoke inhalation on immediate changes in lung chemical mediators. Res Commun Chem Pathol Pharmacol; 1991 Dec;74(3):259-72
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  • Acute smoke exposure caused a significant (p = 0.037) increase in bronchoalveolar lavage fluid levels of leukotriene B4 in the SE rabbits; 643 (+/- 30, SEM) pg/ml compared to 539 (+/- 43, SEM) pg/ml for SS rabbits at 3-4 min post-exposure.

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  • (PMID = 1663646.001).
  • [ISSN] 0034-5164
  • [Journal-full-title] Research communications in chemical pathology and pharmacology
  • [ISO-abbreviation] Res. Commun. Chem. Pathol. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Phosphatidylcholines; 0 / Smoke; 11062-77-4 / Superoxides; 1HGW4DR56D / Leukotriene B4; DCR9Z582X0 / Epoprostenol; R802O5NILK / piriprost
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74. Trischitta V, Italia S, Mazzarino S, Buscema M, Rabuazzo AM, Sangiorgio L, Squatrito S, Vigneri R: Comparison of combined therapies in treatment of secondary failure to glyburide. Diabetes Care; 1992 Apr;15(4):539-42
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  • The addition of metformin was more effective than the addition of insulin (P less than 0.01) in improving PPPG in the 8 patients with higher post-glucagon C-peptide levels.

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  • (PMID = 1499473.001).
  • [ISSN] 0149-5992
  • [Journal-full-title] Diabetes care
  • [ISO-abbreviation] Diabetes Care
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / C-Peptide; 0 / Hemoglobin A, Glycosylated; 53027-39-7 / Insulin, Isophane; 9100L32L2N / Metformin; SX6K58TVWC / Glyburide
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75. Biagini G, Zoli M, Fuxe K, Agnati LF: L-deprenyl increases GFAP immunoreactivity selectively in activated astrocytes in rat brain. Neuroreport; 1993 Jul;4(7):955-8
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  • When post-treated for 42 days, however, L-deprenyl no longer increased GFAP IR although reactive astrocytes were still present in the lesioned area.

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  • (PMID = 8369488.001).
  • [ISSN] 0959-4965
  • [Journal-full-title] Neuroreport
  • [ISO-abbreviation] Neuroreport
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 2K1V7GP655 / Selegiline; EC 1.4.3.4 / Monoamine Oxidase
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76. Martin E, Ramsay G, Mantz J, Sum-Ping ST: The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. J Intensive Care Med; 2003 Jan-Feb;18(1):29-41
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  • Dexmedetomidine was evaluated for sedation of 401 post-surgical patients in this double-blind, randomized, placebo-controlled, multicenter trial.
  • Dexmedetomidine or saline was started on arrival in the intensive care unit (ICU) (1.0 mcg/kg for 10 minutes), then titrated at 0.2 to 0.7 mcg/kg/h to effect.

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  • (PMID = 15189665.001).
  • [ISSN] 0885-0666
  • [Journal-full-title] Journal of intensive care medicine
  • [ISO-abbreviation] J Intensive Care Med
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adrenergic alpha-2 Receptor Agonists; 0 / Adrenergic alpha-Agonists; 0 / Hypnotics and Sedatives; 67VB76HONO / Dexmedetomidine; YI7VU623SF / Propofol
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77. Hearn CM, Shaw G, Short RV, Renfree MB: Effects of cabergoline on reproduction in three families of Australian marsupials. J Reprod Fertil; 1998 May;113(1):151-7
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  • During early lactation in tammars (56-69 days post partum), an intramuscular injection transiently retarded growth of the young, although they subsequently survived.
  • Intramuscular injection during late lactation (166-199 days post partum) apparently suppressed milk secretion since pouch young lost up to 20% of their bodyweight or died within 7 days of treatment.

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  • (PMID = 9713388.001).
  • [ISSN] 0022-4251
  • [Journal-full-title] Journal of reproduction and fertility
  • [ISO-abbreviation] J. Reprod. Fertil.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Dopamine Agonists; 0 / Ergolines; 9002-62-4 / Prolactin; LL60K9J05T / cabergoline
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78. Kanaley JA, Heden TD, Liu Y, Whaley-Connell AT, Chockalingam A, Dellsperger KC, Fairchild TJ: Short-term aerobic exercise training increases postprandial pancreatic polypeptide but not peptide YY concentrations in obese individuals. Int J Obes (Lond); 2014 Feb;38(2):266-71
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  • RESULTS: Incremental area under the curve (iAUC) for PP increased significantly with training (pre: 2788±753; post: 3845±830 pg ml(-1)·per min for 12 h; P<0.001), but there was no difference in the PP response to each meal.
  • The initial PP response to the first meal increased (ΔPP(min 20-0): pre 86±25; post 140±36 pg ml(-1); P<0.05) with training.

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  • (PMID = 23736355.001).
  • [ISSN] 1476-5497
  • [Journal-full-title] International journal of obesity (2005)
  • [ISO-abbreviation] Int J Obes (Lond)
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R21 DK084467; United States / NIDDK NIH HHS / DK / R21DK084467-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Insulin; 106388-42-5 / Peptide YY; 59763-91-6 / Pancreatic Polypeptide
  • [Other-IDs] NLM/ NIHMS466785; NLM/ PMC3773306
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79. Sreenivasa Baba C, Alexander G, Kalyani B, Pandey R, Rastogi S, Pandey A, Choudhuri G: Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis. J Gastroenterol Hepatol; 2006 Jan;21(1 Pt 1):191-8
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  • Each patient was advised regular aerobic exercise for 30 min duration per day, and trained to achieve a heart rate of 60-70% of his/her maximal heart rate for at least 5 days a week.
  • Serum ALT did not normalize in any of the 15 patients who failed to comply with the exercise program; their pre- and post-AST (82.8 and 81.2, respectively) and ALT (98.0 and 96.1, respectively) levels, BMI (27.5 and 27.6, respectively) and WHR (0.99 cm and 0.99 cm, respectively) did not show any significant change at 3 months, and also for an extended mean follow-up period of 5.3 months.

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  • [CommentIn] J Gastroenterol Hepatol. 2007 Apr;22(4):604-5 [17376064.001]
  • (PMID = 16706832.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] EC 2.6.1.1 / Aspartate Aminotransferases; EC 2.6.1.2 / Alanine Transaminase
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80. Oner-Iyidoğan Y, Gürdöl F, Oner P: The effects of acute melatonin and ethanol treatment on antioxidant enzyme activities in rat testes. Pharmacol Res; 2001 Aug;44(2):89-93
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  • The third group received only 30% alcohol 3 g kg(-1)bw twice daily.
  • The product of lipid peroxidation, malondialdehyde (MDA) and antioxidant enzymes, superoxide dismutase (Cu--Zn SOD), glutathione peroxidase (GPx) and catalase (CAT) were measured in the post-mitochondrial fraction of the testes.

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  • [Copyright] Copyright 2001 Academic Press.
  • (PMID = 11516256.001).
  • [ISSN] 1043-6618
  • [Journal-full-title] Pharmacological research
  • [ISO-abbreviation] Pharmacol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Free Radical Scavengers; 0 / Free Radicals; 3K9958V90M / Ethanol; 4Y8F71G49Q / Malondialdehyde; EC 1.11.1.6 / Catalase; EC 1.11.1.9 / Glutathione Peroxidase; EC 1.15.1.1 / Superoxide Dismutase; JL5DK93RCL / Melatonin
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81. Badescu M, Badulescu O, Badescu L, Ciocoiu M: Effects of Sambucus nigra and Aronia melanocarpa extracts on immune system disorders within diabetes mellitus. Pharm Biol; 2015 Apr;53(4):533-9
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  • Seventy-two hours post-administration of both substances in the diabetic groups, the TNF-α level returns to the values read 24 h after substance administration.

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  • (PMID = 25327310.001).
  • [ISSN] 1744-5116
  • [Journal-full-title] Pharmaceutical biology
  • [ISO-abbreviation] Pharm Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anthocyanins; 0 / Immunologic Factors; 0 / Plant Extracts; 0 / Polyphenols; 0 / Tumor Necrosis Factor-alpha; 82115-62-6 / Interferon-gamma
  • [Keywords] NOTNLM ; Fibrinogen / IFN-γ / TNF-α / polyphenols
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82. O'Neill BV, Croft RJ, Mann C, Dang O, Leung S, Galloway MP, Phan KL, Nathan PJ: High-dose glycine impairs the prepulse inhibition measure of sensorimotor gating in humans. J Psychopharmacol; 2011 Dec;25(12):1632-8
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  • PPI was recorded 45 min post treatment using electromyography of the eye-blink response.

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  • (PMID = 20615931.001).
  • [ISSN] 1461-7285
  • [Journal-full-title] Journal of psychopharmacology (Oxford, England)
  • [ISO-abbreviation] J. Psychopharmacol. (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, N-Methyl-D-Aspartate; TE7660XO1C / Glycine
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83. Shati AA: Effects of Origanum majorana L. on cadmium induced hepatotoxicity and nephrotoxicity in albino rats. Saudi Med J; 2011 Aug;32(8):797-805
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  • Thirty-six male albino rats were divided into 6 groups: control, Cd, OM, OM+Cd, OM pre-treated (received OM extract for 14 days followed by Cd for 14 days), OM post-treated (received Cd for 14 days followed by OM extract for 14 days).
  • Levels of all disrupted parameters were alleviated by co-administration and post-administration of OM extract.


84. Mori Y, Ojima K, Fuujimori Y, Aoyagi I, Kusama H, Yamazaki Y, Kojima M, Shibata N, Itoh Y, Tajima N: Effects of mitiglinide on glucose-induced insulin release into the portal vein and fat-induced triglyceride elevation in prediabetic and diabetic OLETF rats. Endocrine; 2006 Apr;29(2):309-15
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  • CONCLUSION: Mitiglinide exhibited fast-onset and short-acting insulin-secretagogic effects, inhibiting post-glucose challenge increases in glucose levels and post-fat challenge increases in TG levels.

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  • [ErratumIn] Endocrine. 2006 Jun;29(3):517. Fujimori, Y [corrected to Fuujimori, Y]; Kojima, S [corrected to Kojima, M]
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  • (PMID = 16785606.001).
  • [ISSN] 1355-008X
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Cyclohexanes; 0 / Indoles; 0 / Insulin; 0 / Isoindoles; 0 / RNA, Messenger; 0 / Sulfonylurea Compounds; 0 / Triglycerides; 41X3PWK4O2 / nateglinide; 47E5O17Y3R / Phenylalanine; 6KY687524K / glimepiride; D86I0XLB13 / mitiglinide; EC 3.1.1.34 / Lipoprotein Lipase; SX6K58TVWC / Glyburide
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85. Brownlow MA, Hutchins DR, Johnston KG: Reference values for equine peritoneal fluid. Equine Vet J; 1981 Apr;13(2):127-30
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  • Samples were collected ante mortem or within 1 h post mortem.
  • The mean total nucleated cell count (+/- sd) was 4.33 +/- 2.5 x 10(9)/litre (range 1.5-10.1 x 10(9)/litre) and, proportionally, polymorphonuclear leucocytes averaged 45.2 per cent, mononuclear phagocytes 47 per cent, lymphocytes 7.8 per cent, eosinophils 0.7 per cent and basophils and mast cells zero.
  • Eosinophils were not usually seen but 6 samples had 1 to 5 per cent.

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  • (PMID = 7250103.001).
  • [ISSN] 0425-1644
  • [Journal-full-title] Equine veterinary journal
  • [ISO-abbreviation] Equine Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
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86. Machado L, Magnusson M, Paul NA, de Nys R, Tomkins N: Effects of marine and freshwater macroalgae on in vitro total gas and methane production. PLoS One; 2014;9(1):e85289
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  • Post-fermentation parameters, including CH4 production, pH, ammonia, apparent organic matter degradability (OMd), and volatile fatty acid (VFA) concentrations were measured.

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  • (PMID = 24465524.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fatty Acids, Volatile; 0 / Gases; 7664-41-7 / Ammonia; OP0UW79H66 / Methane
  • [Other-IDs] NLM/ PMC3898960
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87. Miyano G, Okuyama H, Koga H, Okawada M, Doi T, Takahashi T, Nakamura H, Suda K, Lane GJ, Okazaki T, Yamataka A: Type-A long-gap esophageal atresia treated by thoracoscopic esophagoesophagostomy after sequential extrathoracic esophageal elongation (Kimura's technique). Pediatr Surg Int; 2013 Nov;29(11):1171-5
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  • TEE was successful in 3; 1 required thoracotomy, then re-anastomosis after 11 months of anastomosis leakage; 2 cases with post-TEE anastomosis leakage were treated conservatively.

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  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
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88. Anderwald CH, Tura A, Promintzer-Schifferl M, Prager G, Stadler M, Ludvik B, Esterbauer H, Bischof MG, Luger A, Pacini G, Krebs M: Alterations in gastrointestinal, endocrine, and metabolic processes after bariatric Roux-en-Y gastric bypass surgery. Diabetes Care; 2012 Dec;35(12):2580-7
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  • RESEARCH DESIGN AND METHODS: To distinctively unveil effects of RYGB surgery on β-cell function and glucose turnover in skeletal muscle, liver, and gut, nondiabetic, morbidly obese patients were studied before (pre-OP, five female/one male, BMI: 49 ± 3 kg/m(2), 43 ± 2 years of age) and 7 ± 1 months after (post-OP, BMI: 37 ± 3 kg/m(2)) RYGB surgery, compared with matching obese (CON(ob), five female/one male, BMI: 34 ± 1 kg/m(2), 48 ± 3 years of age) and lean controls (CON(lean), five female/one male, BMI: 22 ± 0 kg/m(2), 42 ± 2 years of age).
  • Oral glucose tolerance tests (OGTTs), hyperinsulinemic-isoglycemic clamp tests, and mechanistic mathematical modeling allowed determination of whole-body insulin sensitivity (M/I), OGTT and clamp test β-cell function, and gastrointestinal glucose absorption.
  • RESULTS: Post-OP lost (P < 0.0001) 35 ± 3 kg body weight.
  • During OGTT, post-OP showed ≥15% reduced plasma glucose from 120 to 180 min (≤4.5 mmol/L), and 29-fold elevated active glucagon-like peptide-1 (GLP-1) dynamic areas under the curve, which tightly correlated (r = 0.837, P < 0.001) with 84% increased β-cell secretion.
  • Insulinogenic index (0-30 min) in post-OP was ≥29% greater (P < 0.04).
  • At fasting, post-OP showed approximately halved insulin secretion (P < 0.05 vs. pre-OP).
  • Insulin-stimulated insulin secretion in post-OP was 52% higher than before surgery, but 1-2 pmol/min(2) lower than in CON(ob)/CON(lean) (P < 0.05).
  • Gastrointestinal glucose absorption was comparable in pre-OP and post-OP, but 9-26% lower from 40 to 90 min in post-OP than in CON(ob)/CON(lean) (P < 0.04).
  • CONCLUSIONS: RYGB surgery leads to decreased plasma glucose concentrations in the third OGTT hour and exaggerated β-cell function, for which increased GLP-1 release seems responsible, whereas gastrointestinal glucose absorption remains unchanged but lower than in matching controls.

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  • (PMID = 22923664.001).
  • [ISSN] 1935-5548
  • [Journal-full-title] Diabetes care
  • [ISO-abbreviation] Diabetes Care
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 89750-14-1 / Glucagon-Like Peptide 1
  • [Other-IDs] NLM/ PMC3507557
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89. Parodi-Rullan R, Barreto-Torres G, Ruiz L, Casasnovas J, Javadov S: Direct renin inhibition exerts an anti-hypertrophic effect associated with improved mitochondrial function in post-infarction heart failure in diabetic rats. Cell Physiol Biochem; 2012;29(5-6):841-50
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  • [Title] Direct renin inhibition exerts an anti-hypertrophic effect associated with improved mitochondrial function in post-infarction heart failure in diabetic rats.
  • BACKGROUND: In addition to hypertension control, direct renin inhibition has been shown to exert direct beneficial effects on the heart in post-infarction cardiac remodeling.
  • This study elucidates the possible contribution of mitochondria to the anti-hypertrophic effects of the direct renin inhibitor aliskiren in post-infarction heart failure complicated with diabetes in rats.
  • Post-infarction HF was induced by coronary artery ligation for 4 weeks.
  • In addition, heart failure reduced expression of the major mitochondrial sirtuin, SIRT3 and increased acetylation of cyclophilin D, a regulatory component of the PTP.
  • CONCLUSION: Our results demonstrate that aliskiren attenuates post-infarction remodeling which is associated with its beneficial effects on mitochondria.

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  • [Copyright] Copyright © 2012 S. Karger AG, Basel.
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  • (PMID = 22613984.001).
  • [ISSN] 1421-9778
  • [Journal-full-title] Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
  • [ISO-abbreviation] Cell. Physiol. Biochem.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / G12 RR003051; United States / NHLBI NIH HHS / HL / SC1 HL118669; United States / NCRR NIH HHS / RR / G12RR-03051
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Amides; 0 / Fumarates; 502FWN4Q32 / aliskiren; EC 3.4.23.15 / Renin
  • [Other-IDs] NLM/ NIHMS443884; NLM/ PMC3980674
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90. Burton PR, Button B, Brown W, Lee M, Roberts S, Hassen S, Bailey M, Smith A, Snell G: Medium-term outcome of fundoplication after lung transplantation. Dis Esophagus; 2009;22(8):642-8
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  • [Title] Medium-term outcome of fundoplication after lung transplantation.
  • Forced expiratory volume-1% predicted was 72.9 (20.9), 6 months prior to fundoplication and 70.4 (26.8), six months post-fundoplication, P= 0.33.
  • Fundoplication does not reverse any decline in lung function when performed at a late stage post-lung transplantation in patients with objectively confirmed GERD.
  • Whether performing fundoplication early post-lung transplant in selected patients can prevent BOS and improve long-term outcomes requires formal evaluation.

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  • (PMID = 19515194.001).
  • [ISSN] 1442-2050
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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91. Ciccocioppo R, Panocka I, Froldi R, Quitadamo E, Massi M: Ethanol induces conditioned place preference in genetically selected alcohol-preferring rats. Psychopharmacology (Berl); 1999 Jan;141(3):235-41
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  • In ethanol-experienced rats 0.7 or 1.5, but not 0.35 or 2.8 g/kg ethanol significantly increased in comparison to controls the time spent in the ethanol-associated previously non-preferred compartment, which became preferred in the post-conditioning test.

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  • (PMID = 10027504.001).
  • [ISSN] 0033-3158
  • [Journal-full-title] Psychopharmacology
  • [ISO-abbreviation] Psychopharmacology (Berl.)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] GERMANY
  • [Chemical-registry-number] 0 / Central Nervous System Depressants; 3K9958V90M / Ethanol
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92. Neal BS, Sparber SB: Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine. J Pharmacol Exp Ther; 1986 Jan;236(1):157-65
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  • Withdrawal was precipitated with naloxone (5 mg/kg) 24, 48 and 120 hr post implantation.
  • Naloxone-precipitated weight loss was also attenuated 48 and 120 hr post implantation.
  • At 120 hr post implantation, rats were decapitated 1 hr after the administration of naloxone and trunk blood was collected.

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  • (PMID = 3001281.001).
  • [ISSN] 0022-3565
  • [Journal-full-title] The Journal of pharmacology and experimental therapeutics
  • [ISO-abbreviation] J. Pharmacol. Exp. Ther.
  • [Language] eng
  • [Grant] United States / NIDA NIH HHS / DA / DA-01880; United States / NIGMS NIH HHS / GM / GM-07397; United States / NCRR NIH HHS / RR / RR-05385
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Dibenzazepines; 0 / Receptors, Adrenergic, alpha; 250PJI13LM / Mianserin; 333DO1RDJY / Serotonin; 36B82AMQ7N / Naloxone; MN3L5RMN02 / Clonidine; W980KJ009P / Corticosterone
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93. Liu XM, Chen YZ, Huang MJ, Liu X, Guo JR: [The potential prognostic influence of granulocyte-colony stimulating factor in acute leukemia]. Zhonghua Nei Ke Za Zhi; 2005 Jul;44(7):518-21
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  • METHODS: In 171 evaluable cases with AL, the complete remission (CR) rate post first course of chemotherapy, CR rate, effective rate, duration of leucopenia post chemotherapy, CR duration, lifespan and the relationship between the dosage of G-CSF and CR duration or lifespan were retrospectively analyzed with Chi-square test, paired t-test, Cox regression, Kaplan-Meier and rank correlation method.
  • However, there was no statistical difference between the two groups in the CR rate post first course of chemotherapy, CR rate and the effective rate of treatment. (2) Use of G-CSF did not affect CR durations of ALL patients, but shortened that of AML patients. (3) The application of G-CSF had little effect on the lifespan of ALL patients.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Granulocyte Colony-Stimulating Factor / administration & dosage. Leukemia, Myeloid, Acute / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy

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  • (PMID = 16080844.001).
  • [ISSN] 0578-1426
  • [Journal-full-title] Zhonghua nei ke za zhi
  • [ISO-abbreviation] Zhonghua Nei Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 143011-72-7 / Granulocyte Colony-Stimulating Factor
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94. Hamida SB, Tracqui A, de Vasconcelos AP, Szwarc E, Lazarus C, Kelche C, Jones BC, Cassel JC: Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA. Int J Neuropsychopharmacol; 2009 Jul;12(6):749-59
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  • EtOH potentiated MDMA-induced hyperactivity mainly during the first 60 min post-administration.

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  • (PMID = 19046482.001).
  • [ISSN] 1469-5111
  • [Journal-full-title] The international journal of neuropsychopharmacology
  • [ISO-abbreviation] Int. J. Neuropsychopharmacol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Central Nervous System Depressants; 0 / Hallucinogens; 3K9958V90M / Ethanol; 4764-17-4 / 3,4-Methylenedioxyamphetamine; KE1SEN21RM / N-Methyl-3,4-methylenedioxyamphetamine
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95. Dong LJ, Chen H, Jiang M, Hu LD, Qin MQ, Zhang WJ, Yu ZY, Wu SK, Chen XL, Bao YH, Song ST, Liu DQ: [Selected CD34+ cell autologous transplantation for advanced malignant tumors]. Zhonghua Zhong Liu Za Zhi; 2003 Mar;25(2):183-5
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  • [Title] [Selected CD34+ cell autologous transplantation for advanced malignant tumors].
  • OBJECTIVE: To determine the clinical results of selected CD34(+) cell autologous transplantation in advanced malignant tumors.
  • METHODS: After pretreatment, fifteen patients aged 12 - 70 (49.5) years with various Stage III or IV malignant tumors were given the sorted CD34(+) cells collected by magnetic-activated cell sorting (Clini MACS, Milteny Biotech, Germany).
  • RESULTS: Peripheral blood progenitor cells (PBPC) from the patients were mobilized by chemotherapy and G-CSF 5 micro g/kg per day.
  • CD34(+) cells gave 2.0 - 5 log depletion after cell sorting, with a median yield of CD34(+) selected cells of 2.4 (0.15 - 12.03) x 10(6)/kg.
  • The median time of neutrophil recovery > 1.0 x 10(9)/L and platelet recovery > 20 x 10(9)/L post-transplantation were 14 (8 - 26) days and 13 (11 - 35) days, respectively.
  • Selected CD34(+) cell transplantation, being a safe approach, may improve the clinical outcome even in patients with advanced malignant tumors.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Hematopoietic Stem Cell Transplantation / adverse effects. Humans. Male. Middle Aged. Survival Rate. Transplantation, Autologous

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  • (PMID = 12795850.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD34
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96. Melia KF, Ehlers CL, LeBrun CJ, Koob GF: Post-learning ethanol effects on a water-finding task in rats. Pharmacol Biochem Behav; 1986 Jun;24(6):1813-5
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  • [Title] Post-learning ethanol effects on a water-finding task in rats.
  • Ethanol's post-training facilitation of memory was examined using a latent learning paradigm known as the "water-finding task."
  • These results suggest that under conditions of post-training ethanol, trial 2 behavior is more similar to, or controlled by, trial 1 behavior and are consistent with the argument that, under certain training and testing contexts, ethanol can come to exert control over a response's recurrence.

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  • (PMID = 3737649.001).
  • [ISSN] 0091-3057
  • [Journal-full-title] Pharmacology, biochemistry, and behavior
  • [ISO-abbreviation] Pharmacol. Biochem. Behav.
  • [Language] ENG
  • [Grant] United States / NIAAA NIH HHS / AA / P60 AA006420; United States / NIAAA NIH HHS / AA / R01 AA006059; United States / NIAAA NIH HHS / AA / NIAAA 06059; United States / NIAAA NIH HHS / AA / NIAAA 06420
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 3K9958V90M / Ethanol
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97. Sileika AS, Gaigalis K, Kutra G, Smitiene A: Factors affecting N and P losses from small catchments (Lithuania). Environ Monit Assess; 2005 Mar;102(1-3):359-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In summary, extensive agriculture in the post-Soviet countries has reduced the importance of agricultural activity for the extent of nutrient losses and agricultural factors (cultivation, fertilisation and livestock density) are 'responsible' for the losses only in the region of sufficient agricultural activity (N input--71.5 kg N ha(-1), livestock density--0.87 LU ha(-1)).

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  • (PMID = 15869196.001).
  • [ISSN] 0167-6369
  • [Journal-full-title] Environmental monitoring and assessment
  • [ISO-abbreviation] Environ Monit Assess
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Fertilizers; 0 / Soil; 0 / Water Pollutants, Chemical; 27YLU75U4W / Phosphorus; N762921K75 / Nitrogen
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98. Bruckental I, Oldham JD, Sutton JD: Glucose and urea kinetics in cows in early lactation. Br J Nutr; 1980 Jul;44(1):33-45
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  • For 2 weeks after calving they were fed 3 kg hay (147 g crude protein (nitrogen X 6.25; CP)/kg dry matter (DM) plus 9 kg concentrates (177 g CP/kg DM) per d and thereafter 4 kg hay plus 12 kg concentrates/d. 2.
  • At approximately the 2nd, 4th and 9th weeks post-partum each cow was given a single intravenous dose of [14C]urea (1 mCi) and [6-3H]glucose (1.5 mCi).
  • Following this, jugular venous blood samples were withdrawn up to 26 h post-injection.
  • 6. Glucose IRL rose (P < 0.05) between the 2nd and 9th weeks post-partum, perhaps due to the increase in feed intake.

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  • (PMID = 7426603.001).
  • [ISSN] 0007-1145
  • [Journal-full-title] The British journal of nutrition
  • [ISO-abbreviation] Br. J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Dietary Proteins; 8W8T17847W / Urea; IY9XDZ35W2 / Glucose
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99. Marion J, Biernat M, Thomas F, Savary G, Le Breton Y, Zabielski R, Le Huërou-Luron I, Le Dividich J: Small intestine growth and morphometry in piglets weaned at 7 days of age. effects of level of energy intake. Reprod Nutr Dev; 2002 Jul-Aug;42(4):339-54
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  • Two trials involving a total of 56 pigs were conducted to examine the effects of weaning at 7 d of age (trial 1) and of energy intake level and length of post-weaning underfeeding period (trial 2) on small intestinal (SI) development and morphometry.
  • Intestinal morphometrical changes are dependent on SI site and days post-weaning.
  • Villous atrophy on d 3 and recovery on d 14 post-weaning were greater and occurred earlier in the proximal than in the medial and distal SI.
  • Moreover, after 4 d of refeeding, underfed piglets showed similar villous characteristics to piglets fed a continuously high feeding level after weaning stressing that capacities of intestinal restoration were not affected by the length of the post-weaning underfeeding period.
  • Overall, the present results suggest a spatial and temporal effect of weaning on villous atrophy and recovery, and that the level of energy intake is a major factor accounting for the post-weaning villous height.

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  • (PMID = 12510875.001).
  • [ISSN] 0926-5287
  • [Journal-full-title] Reproduction, nutrition, development
  • [ISO-abbreviation] Reprod. Nutr. Dev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
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100. Wu S, Zhang F, Huang Z, Liu H, Xie C, Zhang J, Thacker PA, Qiao S: Effects of the antimicrobial peptide cecropin AD on performance and intestinal health in weaned piglets challenged with Escherichia coli. Peptides; 2012 Jun;35(2):225-30
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  • The incidence of diarrhea post-challenge in the antibiotic and cecropin AD treatments decreased compared with the control piglets.

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  • [Copyright] Copyright © 2012. Published by Elsevier Inc.
  • (PMID = 22490448.001).
  • [ISSN] 1873-5169
  • [Journal-full-title] Peptides
  • [ISO-abbreviation] Peptides
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / Immunoglobulin A, Secretory; 0 / Immunoglobulin G; 0 / Insect Proteins; 0 / Interleukin-1beta; 0 / Interleukin-6; 116811-00-8 / cecropin AD protein, insect; 1392-21-8 / Kitasamycin; Z67X93HJG1 / Colistin
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