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1. |||....... 25%  Buescher JJ: Temporomandibular joint disorders. Am Fam Physician; 2007 Nov 15;76(10):1477-82
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  • [Title] Temporomandibular joint disorders.
  • Temporomandibular joint disorders are common in adults; as many as one third of adults report having one or more symptoms, which include jaw or neck pain, headache, and clicking or grating within the joint.
  • Most symptoms improve without treatment, but various noninvasive therapies may reduce pain for patients who have not experienced relief from self-care therapies.
  • Physical therapy modalities (e.g., iontophoresis, phonophoresis), psychological therapies (e.g., cognitive behavior therapy), relaxation techniques, and complementary therapies (e.g., acupuncture, hypnosis) are all used for the treatment of temporomandibular joint disorders; however, no therapies have been shown to be uniformly superior for the treatment of pain or oral dysfunction.
  • Dental occlusion therapy (e.g., oral splinting) is a common treatment for temporomandibular joint disorders, but a recent systematic review found insufficient evidence for or against its use.
  • Some patients with intractable temporomandibular joint disorders develop chronic pain syndrome and may benefit from treatment, including antidepressants or cognitive behavior therapy.
  • [MeSH-major] Temporomandibular Joint Disorders
  • [MeSH-minor] Anti-Inflammatory Agents / administration & dosage. Cognitive Therapy / methods. Diagnosis, Differential. Humans. Injections, Intra-Articular. Physical Therapy Modalities

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  • [SummaryForPatientsIn] Am Fam Physician. 2007 Nov 15;76(10):1483-4 [18052013.001]
  • (PMID = 18052012.001).
  • [ISSN] 0002-838X
  • [Journal-full-title] American family physician
  • [ISO-abbreviation] Am Fam Physician
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents
  • [Number-of-references] 23
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2. |......... 9%  Veves A, Akbari CM, Primavera J, Donaghue VM, Zacharoulis D, Chrzan JS, DeGirolami U, LoGerfo FW, Freeman R: Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration. Diabetes; 1998 Mar;47(3):457-63
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  • [Title] Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration.
  • Vasodilation on the dorsal foot in response to heating and iontophoresis of acetylcholine (endothelium-dependent) and sodium nitroprusside (endothelium-independent) were measured using single-point laser Doppler and laser Doppler imaging in diabetic patients with neuropathy (DN), with neuropathy and vascular disease (DI), with Charcot arthropathy (DA), and without complications (D), and in healthy control subjects (C).
  • The endothelial-mediated response to acetylcholine was reduced in the DN (17 [11-25]), DA (22 [2-34]), and DI (13 [2-30]) groups compared with the D (47 [24-58]) and C (44 [31-70], P < 0.001) groups.
  • The non-endothelial-mediated response to sodium nitroprusside was also reduced in the DI (4 [0-18]), DN (17 [9-26]), and DA (21 [11-31]) groups compared with the D (37 [19-41]) and C (44 [26-67], P < 0.0001) groups.
  • There was a significant reduction in vasodilation in the DI group compared with all other groups (P < 0.0001).
  • Reduced expression of ecNOS may be a major contributing factor for endothelial dysfunction.
  • [MeSH-minor] Acetylcholine / diagnostic use. Adult. Aged. Biological Markers / analysis. Biopsy. Cohort Studies. Female. Gene Expression Regulation, Enzymologic. Humans. Iontophoresis / statistics & numerical data. Male. Middle Aged. Nitroprusside / diagnostic use. Reference Values. Vasodilator Agents / diagnostic use


3. |......... 3%  Lee CK, Ching CT, Sun TP, Tsai CL, Huang W, Huang HH, Kuo JF, Lai LH, Chien MY, Tseng HH, Pan HT, Huang SY, Shieh HL, Liu WH, Liu CM, Huang HW: Non-invasive and transdermal measurement of blood uric acid level in human by electroporation and reverse iontophoresis. Int J Nanomedicine; 2010;5:991-7
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  • [Title] Non-invasive and transdermal measurement of blood uric acid level in human by electroporation and reverse iontophoresis.
  • The aim of this study was to find out the optimum combination of electroporation (EP) and reverse iontophoresis (RI) on noninvasive and transdermal determination of blood uric acid level in humans.
  • [MeSH-major] Electroporation / methods. Iontophoresis / methods. Uric Acid / blood

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  • (PMID = 21187918.001).
  • [ISSN] 1178-2013
  • [Journal-full-title] International journal of nanomedicine
  • [ISO-abbreviation] Int J Nanomedicine
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] New Zealand
  • [Chemical-registry-number] 268B43MJ25 / Uric Acid
  • [Other-IDs] NLM/ PMC3010161
  • [Keywords] NOTNLM ; Reverse iontophoresis / electroporation / monitoring / noninvasive / transdermal / uric acid
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View summary of articles of this page
1. Physical therapy modalities (e.g., iontophoresis, phonophoresis), psychological therapies (e.g., cognitive behavior therapy), relaxation techniques, and complementary therapies (e.g., acupuncture, hypnosis) are all used for the treatment of temporomandibular joint disorders; however, no therapies have been shown to be uniformly superior for the treatment of pain or oral dysfunction.

2. Vasodilation on the dorsal foot in response to heating and iontophoresis of acetylcholine (endothelium-dependent) and sodium nitroprusside (endothelium-independent) were measured using single-point laser Doppler and laser Doppler imaging in diabetic patients with neuropathy (DN), with neuropathy and vascular disease (DI), with Charcot arthropathy (DA), and without complications (D), and in healthy control subjects (C).

4. 40 out of 48 patients suffering from chronic intractable pain of diverse etiology (postherpetic, paresthetic, ischaemic and trigeminal neuralgia, alcoholic and diabetic polyneuropathy, meralgia, brachialgia, discopathia, arthropathia and terminal pain) were successfully treated with Vinblastin or Vincristin iontophoresis.

5. [Diclofenac iontophoresis in the treatment of arthrosis].

21. [The iontophoresis with optidase and thiomucase in the treatment of rheumatic soft tissue disorders and osteoarthrosis (author's transl)].

25. [Optidase in the treatment of arthrosis by intramuscular injections and iontophoresis (author's transl)].


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4. ||........ 17%  Knyihár-Csillik E, Szücs A, Csillik B: Iontophoretically applied microtubule inhibitors induce transganglionic degenerative atrophy of primary central nociceptive terminals and abolish chronic autochtonous pain. Acta Neurol Scand; 1982 Oct;66(4):401-12
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  • Transcutaneous iontophoresis of microtubule inhibitors (Vinblastin, Vincristin, Formyl-Leurosin) in rats induces depletion of fluoride-resistant acid phosphatase (FRAP) and transganglionic degenerative atrophy (trggl. deg. atr.) of the central terminals of primary nociceptive neurons, probably via blockade of axoplasmic transport in the peripheral sensory nerves.
  • 40 out of 48 patients suffering from chronic intractable pain of diverse etiology (postherpetic, paresthetic, ischaemic and trigeminal neuralgia, alcoholic and diabetic polyneuropathy, meralgia, brachialgia, discopathia, arthropathia and terminal pain) were successfully treated with Vinblastin or Vincristin iontophoresis.
  • Iontophoretically applied microtubule inhibitors do not affect the blood cell count, have no side-effects and do not impair the skin at the site of application.
  • [MeSH-minor] Acid Phosphatase / metabolism. Animals. Atrophy. Axonal Transport / drug effects. Humans. Iontophoresis. Muridae. Substantia Gelatinosa / drug effects

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  • (PMID = 6183918.001).
  • [ISSN] 0001-6314
  • [Journal-full-title] Acta neurologica Scandinavica
  • [ISO-abbreviation] Acta Neurol. Scand.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] DENMARK
  • [Chemical-registry-number] 0 / Vinca Alkaloids; 54022-49-0 / formyl-leurosine; 57-22-7 / Vincristine; 5V9KLZ54CY / Vinblastine; EC 3.1.3.2 / Acid Phosphatase
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5. |......... 6%  Williame E, Anthoine F, Plissart M: [Diclofenac iontophoresis in the treatment of arthrosis]. J Belge Med Phys Rehabil; 1982;5(2):61-5
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  • [Title] [Diclofenac iontophoresis in the treatment of arthrosis].
  • [Transliterated title] L'ionophorèse au Diclofénac dans le traitement de l'arthrose.
  • [MeSH-major] Diclofenac / administration & dosage. Iontophoresis. Joint Diseases / therapy. Phenylacetates / administration & dosage

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  • (PMID = 7153206.001).
  • [ISSN] 0250-4766
  • [Journal-full-title] Journal belge de médecine physique et de réhabilitation. = Belgisch tijdschrift voor fysische geneeskunde en rehabilitatie
  • [ISO-abbreviation] J Belge Med Phys Rehabil
  • [Language] dut
  • [Publication-type] Journal Article
  • [Publication-country] BELGIUM
  • [Chemical-registry-number] 0 / Phenylacetates; 144O8QL0L1 / Diclofenac
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6. |......... 2%  Cooper IF, Siadaty MS: 'Diseases or Syndromes' associated with 'Iontophoresis Route Of Administration': Top Publications. BioMedLib Review; DiseaseOrSyndrome;IontophoresisRouteOf:705350382. ISSN: 2331-5717. 2014/2/26
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  • [Title] 'Diseases or Syndromes' associated with 'Iontophoresis Route Of Administration': Top Publications.
  • [Transliterated title]
  • Background: There are articles published each month which present 'Disease or Syndrome' for 'iontophoresis route of administration'.
  • Finding such articles is important for researchers, clinicians, and patients.
  • However these articles are spread across thousands of journals, and there are many types of 'Disease or Syndrome'.
  • This makes searching and locating the relevant publications a challenge.
  • We have used BioMedLib's semantic search technology to address the issue, and gathered all the pertinent publications in this review article.
  • Methods: We categorized the publications we found into two groups.
  • We used the strength of textual-association to separate the groups.
  • In group one there are publications with the strongest evidence of association. We focused finding the most relevant publications pertinent to our goal, rather than combining them into a conclusion section. Such textual synthesis will be the focus of our next project.
  • Results: Group one includes 62 publications, and group two 150276 publications.
  • Here are the top 10.
  • Murray AK et al: Vasodilator iontophoresis a possible new therapy for digital ischaemia in systemic sclerosis?.
  • Rossi M et al: Blunted increase of digital skin vasomotion following acetylcholine and sodium nitroprusside iontophoresis in systemic sclerosis patients.
  • Mina R et al: Effectiveness of dexamethasone iontophoresis for temporomandibular joint involvement in juvenile idiopathic arthritis.
  • Gorodkin R et al: Assessment of endothelial function in complex regional pain syndrome type I using iontophoresis and laser Doppler imaging.
  • Costa IA et al: The integration of acetic acid iontophoresis, orthotic therapy and physical rehabilitation for chronic plantar fasciitis: a case study.
  • Soroko YT et al: Treatment of plantar verrucae using 2% sodium salicylate iontophoresis.
  • Başkurt F et al: Comparison of effects of phonophoresis and iontophoresis of naproxen in the treatment of lateral epicondylitis.
  • Kreyden OP: Iontophoresis for palmoplantar hyperhidrosis.
  • Roustit M et al: Cutaneous iontophoresis of treprostinil in systemic sclerosis: a proof-of-concept study.
  • Roustit M et al: Sodium nitroprusside iontophoresis on the finger pad does not consistently increase skin blood flow in healthy controls and patients with systemic sclerosis.

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  • [Copyright] Copyright 2014 Siadaty and Cooper; licensee BioMedLib LLC.
  • (UID = 705350382.001).
  • [ISSN] 2331-5717
  • [Journal-full-title] BioMedLib Review
  • [Language] eng
  • [Publication-type] Review
  • [Publication-country] UNITED STATES
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7. |......... 3%  Lo CW: Transformation by iontophoretic microinjection of DNA: multiple integrations without tandem insertions. Mol Cell Biol; 1983 Oct;3(10):1803-14
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  • Iontophoresis involves the use of an externally applied electric current to expel DNA molecules from the injection micropipette into the impaled cell (microelectrophoresis).
  • Restriction analysis of transformants obtained by using this procedure demonstrated that this method gave strikingly different results from those previously obtained by others with transformants generated by pressure injection.
  • [MeSH-major] Genetic Techniques. Iontophoresis. Microinjections. Transformation, Genetic

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  • (PMID = 6358861.001).
  • [ISSN] 0270-7306
  • [Journal-full-title] Molecular and cellular biology
  • [ISO-abbreviation] Mol. Cell. Biol.
  • [Language] eng
  • [Grant] United States / NIADDK NIH HHS / AM / AM-25779; United States / NCI NIH HHS / CA / CA 31042; United States / NIGMS NIH HHS / GM / GM-30461
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 9007-49-2 / DNA; EC 2.7.1.21 / Thymidine Kinase
  • [Other-IDs] NLM/ PMC370042
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8. |......... 3%  Mina R, Melson P, Powell S, Rao M, Hinze C, Passo M, Graham TB, Brunner HI: Effectiveness of dexamethasone iontophoresis for temporomandibular joint involvement in juvenile idiopathic arthritis. Arthritis Care Res (Hoboken); 2011 Nov;63(11):1511-6
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  • [Title] Effectiveness of dexamethasone iontophoresis for temporomandibular joint involvement in juvenile idiopathic arthritis.
  • OBJECTIVE: Temporomandibular joint (TMJ) involvement is common in juvenile idiopathic arthritis (JIA).
  • Dexamethasone iontophoresis (DIP) uses low-grade electric currents for transdermal dexamethasone delivery into deeper anatomic structures.
  • The purpose of this study was to assess the safety and effectiveness of DIP for the treatment of TMJ involvement in JIA, and to delineate variables that are associated with improvement after DIP.
  • METHODS: Medical records of all JIA patients who underwent DIP for TMJ involvement at a larger tertiary pediatric rheumatology center from 1997-2011 were reviewed.
  • The effectiveness of DIP was assessed by comparing the maximal interincisor opening (MIO(TMJ) ) and the maximal lateral excursion (MLE(TMJ) ) before and after treatment.
  • RESULTS: Twenty-eight patients (ages 2-21 years) who received an average of 8 DIP treatment sessions per involved TMJ were included in the analysis.
  • Side effects of DIP were transient site erythema (86%), skin blister (4%), and metallic taste (4%).
  • CONCLUSION: In this pilot study, DIP appeared to be an effective and safe initial treatment of TMJ involvement in JIA, especially among patients with decreased TMJ measurements.
  • [MeSH-major] Anti-Inflammatory Agents / administration & dosage. Arthritis, Juvenile / drug therapy. Dexamethasone / administration & dosage. Glucocorticoids / administration & dosage. Iontophoresis. Temporomandibular Joint / drug effects. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Administration, Cutaneous. Adolescent. Arthralgia / drug therapy. Arthralgia / physiopathology. Biomechanical Phenomena. Child. Child, Preschool. Facial Pain / drug therapy. Facial Pain / physiopathology. Female. Hospitals, Pediatric. Humans. Male. Ohio. Pain Measurement. Pilot Projects. Range of Motion, Articular. Recovery of Function. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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  • [Copyright] Copyright © 2011 by the American College of Rheumatology.
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  • (PMID = 22034112.001).
  • [ISSN] 2151-4658
  • [Journal-full-title] Arthritis care & research
  • [ISO-abbreviation] Arthritis Care Res (Hoboken)
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / 2UL1RR026314; United States / NIAMS NIH HHS / AR / 5U01-AR51868; United States / NIAMS NIH HHS / AR / P60-AR047884; United States / NIAMS NIH HHS / AR / R03 AR049860; United States / NIAMS NIH HHS / AR / R03 AR049860-03; United States / NIAMS NIH HHS / AR / T32 AR007594-15; United States / PHS HHS / / T32100291; United States / NIAMS NIH HHS / AR / U01 AR055054; United States / NIAMS NIH HHS / AR / U01 AR055054-03; United States / NCRR NIH HHS / RR / UL1 RR026314
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Glucocorticoids; 7S5I7G3JQL / Dexamethasone
  • [Other-IDs] NLM/ NIHMS318622; NLM/ PMC3204193
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9. |......... 6%  Puccetti G, Galassi A, Gigli P, Pierallini FM, Pieraccini A, Scalabrino A: [Iontophoresis of tenoxicam in the therapy of osteoarthrosis]. Clin Ter; 1992 Mar;140(3):239-42
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  • [Title] [Iontophoresis of tenoxicam in the therapy of osteoarthrosis].
  • After a brief physiopathological research about iontophoresis applications, the authors examine this treatment by two drugs (Tenoxicam and acetylsalicylic acid) in a group of patients suffering from painful osteoarthritis.
  • They came to the conclusion that the treatment is efficacious with both substances though realising a quicker analgesic result in the group treated with tenoxicam.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / administration & dosage. Iontophoresis. Osteoarthritis / drug therapy. Piroxicam / analogs & derivatives

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  • (PMID = 1568367.001).
  • [ISSN] 0009-9074
  • [Journal-full-title] La Clinica terapeutica
  • [ISO-abbreviation] Clin Ter
  • [Language] ita
  • [Publication-type] Clinical Trial; Comparative Study; Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] ITALY
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 13T4O6VMAM / Piroxicam; 59804-37-4 / tenoxicam; R16CO5Y76E / Aspirin
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10. |......... 5%  Chantraine A, Ludy JP, Berger D: Is cortisone iontophoresis possible? Arch Phys Med Rehabil; 1986 Jan;67(1):38-40
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  • [Title] Is cortisone iontophoresis possible?
  • Iontophoresis (iontotherapy) is sometimes employed to permit epidermal medication.
  • This work reports our experimentation on steroid iontophoresis both in vitro and in vivo, to determine whether steroids pass through the skin.
  • Then an experimental model with two cylinders, one containing a steroid solution and the other filled with buffer solution separated by human skins was submitted to ionization.
  • The in-vivo experimentation consisted in a study of steroid iontotherapy in four rabbits and in 188 patients.
  • [MeSH-major] Cortisone / administration & dosage. Iontophoresis
  • [MeSH-minor] Adult. Aged. Animals. Arthritis, Rheumatoid / drug therapy. Athletic Injuries / drug therapy. Electrophoresis. Equipment and Supplies. Evaluation Studies as Topic. Female. Humans. Male. Middle Aged. Osteoarthritis / drug therapy. Rabbits. Rheumatic Diseases / drug therapy

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  • (PMID = 3484623.001).
  • [ISSN] 0003-9993
  • [Journal-full-title] Archives of physical medicine and rehabilitation
  • [ISO-abbreviation] Arch Phys Med Rehabil
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] V27W9254FZ / Cortisone
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11. |......... 4%  Akinbo SR, Aiyejusunle CB, Akinyemi OA, Adesegun SA, Danesi MA: Comparison of the therapeutic efficacy of phonophoresis and iontophoresis using dexamethasone sodium phosphate in the management of patients with knee osteoarthritis. Niger Postgrad Med J; 2007 Sep;14(3):190-4
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  • [Title] Comparison of the therapeutic efficacy of phonophoresis and iontophoresis using dexamethasone sodium phosphate in the management of patients with knee osteoarthritis.
  • BACKGROUND AND OBJECTIVE: Many treatment options, including non-pharmacological and pharmacological measures, have been recommended in the management of osteoarthritis (OA).
  • Among the non-pharmacological approach is physiotherapy, which involves the use of physical modalities like, heat therapy, exercise therapy, electrical stimulation, therapeutic ultrasound, iontophoresis, and phonophoresis.
  • This study was therefore designed to compare the effectiveness of 0.4% Dexamethasone sodium phosphate (DEX-P) phonophoresis (PH) with 0.4% DEX-P iontophoresis (ION) therapy in the management of patients with knee joint OA.
  • Ultrasound waves of 1 MHz frequency was applied for 5 minutes to the target knee, so also was the direct current for 10 minutes for 10 sessions treatment period.
  • Western Ontario and McMaster University Osteoarthritis Index (WOMAC) scores, 20 meters ambulatory time, and knee range of motion (ROM) were evaluated before and after therapy as the outcome measures.
  • Twenty (20) metres ambulatory time and knee range of motion also improved significantly in both groups, yet these variables showed no significant difference between the two groups.
  • CONCLUSION: Both therapeutic modalities were found to be effective and generally well tolerated after 10 treatment sessions.
  • DEX-P phonophoresis was not superior to DEX-P iontophoresis in the treatment of patients with OA of the knee.
  • [MeSH-major] Iontophoresis. Osteoarthritis, Knee / therapy. Phonophoresis
  • [MeSH-minor] Adult. Aged. Anti-Inflammatory Agents / therapeutic use. Dexamethasone / analogs & derivatives. Dexamethasone / therapeutic use. Female. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17767200.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 312-93-6 / dexamethasone 21-phosphate; 7S5I7G3JQL / Dexamethasone
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12. |......... 4%  Onigbinde AT, Orolade IA: An assessment of knowledge and opinion of Nigerian physiotherapists on application of iontophoresis in the management of selected skin disorders and arthritis. Technol Health Care; 2012;20(3):169-77
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  • [Title] An assessment of knowledge and opinion of Nigerian physiotherapists on application of iontophoresis in the management of selected skin disorders and arthritis.
  • It is becoming increasingly important to improve knowledge of physiotherapists about iontophoresis since it involves topical medications.
  • There is need to ascertain that physiotherapists have adequate knowledge of the procedure.
  • The primary aim of this study was to determine the opinion and knowledge level of Nigerian physiotherapists about iontophoresis.
  • The result showed that 40 (33.3%) physiotherapists were using iontophoresis as a treatment technique for skin ulcer, hyperhidrosis, and arthritis.
  • Sixty-six (53.7%) of all the respondents chose galvanic (interrupted galvanic) current as the mode used for applying iontophoresis, 43 (35.0%) chose wrongly, faradic current as the current mode while 14 (11.3%) are ignorant of the correct current mode.
  • There was no significant difference in the mean percentage difference in the number of respondent who were correct in the type of current format being utilized for iontophoresis procedure and those who were wrong.
  • Most physiotherapists (62.6%) chose 1-15 minutes as the duration of application for iontophoresis while 31.7% chose their parameters based on patient's tolerance, experience and patient's condition.
  • It was concluded that few physiotherapists in Nigeria have adequate knowledge about iontophoresis and very few are using iontophoresis as a treatment option.
  • [MeSH-major] Arthritis / drug therapy. Health Knowledge, Attitudes, Practice. Iontophoresis / utilization. Physical Therapists / psychology. Skin Diseases / drug therapy

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  • (PMID = 22735732.001).
  • [ISSN] 1878-7401
  • [Journal-full-title] Technology and health care : official journal of the European Society for Engineering and Medicine
  • [ISO-abbreviation] Technol Health Care
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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13. |......... 3%  Leduc BE, Caya J, Tremblay S, Bureau NJ, Dumont M: Treatment of calcifying tendinitis of the shoulder by acetic acid iontophoresis: a double-blind randomized controlled trial. Arch Phys Med Rehabil; 2003 Oct;84(10):1523-7
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  • [Title] Treatment of calcifying tendinitis of the shoulder by acetic acid iontophoresis: a double-blind randomized controlled trial.
  • OBJECTIVE: To assess the effects of acetic acid iontophoresis on the treatment of calcifying tendinitis of the shoulder.
  • INTERVENTIONS: Subjects were randomized into 1 of 2 groups: physiotherapy during 6 weeks (10 sessions) plus acetic acid iontophoresis for the treatment group (n=18) and sham acetic acid iontophoresis for the control group (n=18).
  • Interim analysis showed that, in both groups, treatment led to improvement, as measured by the SPADI score (P=.004), ROM of the shoulder for abduction (P<.001), internal rotation (P=.001), external rotation (P<.001), and the mean number of calcifications per subject (P=.010).
  • Although no formal significant intervention effects (P=.13) were found for the primary endpoint (SPADI), exploratory analyses suggest a greater improvement in the treatment group (P=.001) than in the control group (P=.33).
  • CONCLUSIONS: Despite a trend toward greater improvement in the SPADI score in the treatment group, the use of acetic acid iontophoresis and physiotherapy for the treatment of calcifying tendinitis of the shoulder did not result in better clinical and radiologic effects than those observed in subjects treated by physiotherapyalone.
  • [MeSH-major] Acetic Acid / therapeutic use. Calcinosis / drug therapy. Indicators and Reagents / therapeutic use. Iontophoresis / methods. Joint Diseases / therapy. Tendinopathy / drug therapy
  • [MeSH-minor] Adult. Aged. Double-Blind Method. Female. Humans. Male. Middle Aged. Range of Motion, Articular / physiology. Severity of Illness Index. Shoulder Joint / pathology. Tendons / pathology. Treatment Outcome

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  • (PMID = 14586921.001).
  • [ISSN] 0003-9993
  • [Journal-full-title] Archives of physical medicine and rehabilitation
  • [ISO-abbreviation] Arch Phys Med Rehabil
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indicators and Reagents; Q40Q9N063P / Acetic Acid
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14. |......... 3%  DuPont JS Jr: Clinical use of iontophoresis to treat facial pain. Cranio; 2004 Oct;22(4):297-303
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  • [Title] Clinical use of iontophoresis to treat facial pain.
  • Iontophoresis is a modality that assists with the entry of certain therapeutic medications into injured sites.
  • The above medications have been shown to be beneficial in the treatment of TMD.
  • With iontophoresis, the treating medications can be placed in the target areas in high concentrations.
  • [MeSH-major] Facial Pain / drug therapy. Iontophoresis. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Analgesics / administration & dosage. Anti-Inflammatory Agents / administration & dosage. Humans. Time Factors

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  • (PMID = 15532314.001).
  • [ISSN] 0886-9634
  • [Journal-full-title] Cranio : the journal of craniomandibular practice
  • [ISO-abbreviation] Cranio
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents
  • [Number-of-references] 27
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15. |......... 3%  Lark MR, Gangarosa LP Sr: Iontophoresis: an effective modality for the treatment of inflammatory disorders of the temporomandibular joint and myofascial pain. Cranio; 1990 Apr;8(2):108-19
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  • [Title] Iontophoresis: an effective modality for the treatment of inflammatory disorders of the temporomandibular joint and myofascial pain.
  • The use of the iontophoresis modality for driving medications through the skin for treatment of certain TM dysfunction and myofascial pain dysfunction syndrome was first suggested by Gangarosa and Mahan in 1982.
  • This paper introduces the iontophoresis technique for treatment of inflammatory and myofascial disorders of the craniomandibular system.
  • The historical aspects of iontophoresis in medicine and dentistry is reviewed.
  • As an aid to understanding the clinical applications of this method, a review of diagnostic classification of temporomandibular disorders and an in-depth review of the role of the inflammatory process are provided.
  • Reference is made to the advantages of iontophoresis over hypodermic injection.
  • The basis materials and methods of use of the modality are shown along with a protocol for patient treatment.
  • [MeSH-major] Iontophoresis. Methylprednisolone / administration & dosage. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Adult. Discitis. Dislocations. Epinephrine / administration & dosage. Facial Pain / drug therapy. Female. Humans. Inflammation / drug therapy. Inflammation / physiopathology. Lidocaine / administration & dosage. Male. Myofascial Pain Syndromes / drug therapy. Osteoarthritis


16. |......... 3%  Li LC, Scudds RA, Heck CS, Harth M: The efficacy of dexamethasone iontophoresis for the treatment of rheumatoid arthritic knees: a pilot study. Arthritis Care Res; 1996 Apr;9(2):126-32
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  • [Title] The efficacy of dexamethasone iontophoresis for the treatment of rheumatoid arthritic knees: a pilot study.
  • OBJECTIVE: To examine the efficacy of dexamethasone sodium phosphate (DEX) iontophoresis for the treatment of rheumatoid arthritis (RA) of the knee, and to obtain statistical information for a future randomized controlled trial (RCT).
  • Iontophoresis treatments were given to both groups on days 1, 3, and 5.
  • Five subjects in the experimental group received a mixture of 1 ml of DEX (4 mg/ml) and 1 ml of injectable sterile water; those in the placebo group received 2 ml of saline solution.
  • Pain on movement, at rest, and on pressure, active joint count, and active range of motion, were evaluated on days 1, 5, and 20.
  • The patient's global assessment of treatment efficacy was also assessed on days 5 and 20.
  • CONCLUSION: The results suggest that DEX iontophoresis is more effective than placebo in relieving pain at rest and on movement in the RA knee.
  • Based on the study data, a total of 40 subjects will be required for an RCT of a similar nature.
  • [MeSH-major] Anti-Inflammatory Agents / therapeutic use. Arthritis, Rheumatoid / drug therapy. Dexamethasone / therapeutic use. Iontophoresis. Knee Joint

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  • (PMID = 8970271.001).
  • [ISSN] 0893-7524
  • [Journal-full-title] Arthritis care and research : the official journal of the Arthritis Health Professions Association
  • [ISO-abbreviation] Arthritis Care Res
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 7S5I7G3JQL / Dexamethasone
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17. |......... 3%  Fan DH, Xia B: [Observation on therapeutic effect of heat needle combined with herb iontophoresis and western medicine on rheumatoid arthritis]. Zhongguo Zhen Jiu; 2007 Oct;27(10):731-4
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  • [Title] [Observation on therapeutic effect of heat needle combined with herb iontophoresis and western medicine on rheumatoid arthritis].
  • OBJECTIVE: To search for a therapeutic program for increasing the therapeutic effect of western medicine on rheumatoid arthritis (RA).
  • METHODS: Ninety-six cases of RA were randomly assigned to a treatment group and a control group, 48 cases in each group.
  • The treatment group were treated with heat electroacupuncture instrument with Chinese herb iontophoresis, combined with Meloxicam, Salazosulfamide, and Methotrexate.
  • The control group with simple the western medicine.
  • After treatment of a month, changes of the morning stiff duration, grasp strength, number of tenderness joints, tenderness index, joint rest pain, number of swelling joints, swelling index, assessment of the patient and doctor, and blood rheumatism factor (RF), C-response protein (CRP), erythrocyte sedimentation rate (ESR), the white blood cell (WBC) and platelet counts (PLT) were investigated.
  • RESULTS: The effective rate was 79.2% in the treatment group and 52.1% in the control group, the treatment group being significantly better than the control group (P < 0.01).
  • After treatment of one month, morning stiff duration, average grasp strength of the both hands, tenderness of joint and swelling of joints significantly improved (P < 0.01), with the treatment group being superior to the control group (P < 0.01).
  • After treatment, blood RF, CRP, ESR, WBC and PLT decreased in the two groups (P < 0.01), and the decreases of blood CRP, ESR, PLT in the treatment group were more significantly as compared with the control group (P < 0.01).
  • CONCLUSION: The therapeutic effect of heat needle combined with herb iontophoresis and western medicine is superior to simple medicine for treatment of rheumatoid arthritis.
  • [MeSH-major] Acupuncture Therapy / methods. Arthritis, Rheumatoid / therapy. Drugs, Chinese Herbal / administration & dosage. Iontophoresis
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Male


18. |......... 3%  Aiyejusunle CB, Kola-Korolo TA, Ajiboye OA: Comparison of the effects of tens and sodium salicylate iontophoresis in the management of osteoarthritis of the knee. Nig Q J Hosp Med; 2007 Jan-Mar;17(1):30-4
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  • [Title] Comparison of the effects of tens and sodium salicylate iontophoresis in the management of osteoarthritis of the knee.
  • The aim of this study was to compare the effects of transcutaneous electrical nerve stimulation (TENS) and sodium salicylate Iontophoresis on pain and functional disability in patients with osteoarthritis of the knee.
  • Twenty (20) subjects participated in this study.
  • They were assigned to either the TENS or Iontophoresis group.
  • Electro-medical supplies, while Iontophoresis treatment was delivered using a Galvanic current machine by F.W.
  • The subjects levels of pain and functional disability prior to commencement of treatment and after the 6 weeks of treatment was taken using the Visual Analogue Scale (VAS) and Disability Index Questionnaire for patients with osteoarthritis of the knee joint(s).
  • Patients treated with Sodium salicylate iontophoresis had a more statistically significant reduction of pain and functional disability in comparison with TENS group (P < 0.05).
  • It is hereby suggested that the use of sodium salicylate iontophoresis and TENS be included in treatment of osteoarthritis to enhance pain relief and functional activity.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Iontophoresis / methods. Osteoarthritis, Knee / complications. Pain Management. Sodium Salicylate / therapeutic use. Transcutaneous Electric Nerve Stimulation / methods
  • [MeSH-minor] Activities of Daily Living. Adult. Age Distribution. Aged. Hospitals, University. Humans. Middle Aged. Nigeria / epidemiology. Pain / diagnosis. Pain / etiology. Pain Measurement. Patient Selection. Questionnaires. Statistics, Nonparametric. Treatment Outcome

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  • (PMID = 17688170.001).
  • [ISSN] 0189-2657
  • [Journal-full-title] Nigerian quarterly journal of hospital medicine
  • [ISO-abbreviation] Nig Q J Hosp Med
  • [Language] eng
  • [Publication-type] Comparative Study; Controlled Clinical Trial; Journal Article
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; WIQ1H85SYP / Sodium Salicylate
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19. |......... 2%  Sallì L: [Efficacy and tolerability of ketoprofene administered through iontophoresis in rheumatoid arthritis. Results from a multicentric study]. Clin Ter; 1993 Jun;142(6):533-7
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  • [Title] [Efficacy and tolerability of ketoprofene administered through iontophoresis in rheumatoid arthritis. Results from a multicentric study].
  • [Transliterated title] Attività e tollerabilità del ketoprofene somministrato per jonoforesi nella patologia artroreumatica. Risultati di uno studio policentrico.
  • Three-hundred and twelve patients with osteoarthritic diseases were admitted to a multicenter clinical trial.
  • The patients were given 100 mg Ketoprofen twice-a-day by iontophoresis for 10 consecutive days.
  • Two allergic skin reactions of a mild degree (0.6%) were registered.
  • Therefore, Ketoprofen administered by iontophoresis showed to be efficacious and safe in the treatment of acute osteoarthritic diseases also in high risk patients.
  • [MeSH-major] Arthritis, Rheumatoid / drug therapy. Ketoprofen / therapeutic use. Osteoarthritis / drug therapy
  • [MeSH-minor] Acute Disease. Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Drug Evaluation. Female. Humans. Iontophoresis. Male. Middle Aged


20. |......... 2%  Bender T, Bariska J, Rojkovich B, Bálint G: Etofenamate levels in human serum and synovial fluid following iontophoresis. Arzneimittelforschung; 2001;51(6):489-92
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  • [Title] Etofenamate levels in human serum and synovial fluid following iontophoresis.
  • The absorption of etofenamate (CAS 30544-47-9, Rheumon gel) by iontophoresis in 11 patients with low back pain and in 13 patients with synovitis of the knee was evaluated.
  • During the 5-day treatment period, the test gel in a quantity corresponding to 100 mg etofenamate was applied to affected body regions every day by 20-min iontophoresis sessions.
  • Two hours after the fifth application, the concentration of etofenamate in serum and synovial fluid (in patients who had knee joint iontophoresis) were measured by HPLC.
  • Iontophoresis of etofenamate into the lumbar region as well as to the knee joint resulted in consistent serum levels: 219 +/- 136.3 micrograms/l and 191 +/- 84.6 micrograms/l, respectively.
  • The authors conclude that with topical application of etofenamate by iontophoresis the drug appears not only in the serum but also--with higher levels--in the synovial fluid.
  • [MeSH-major] Anti-Inflammatory Agents / pharmacokinetics. Flufenamic Acid / pharmacokinetics. Synovial Fluid / metabolism
  • [MeSH-minor] Administration, Topical. Arthritis, Rheumatoid / drug therapy. Chromatography, High Pressure Liquid. Female. Humans. Iontophoresis. Low Back Pain / drug therapy. Male. Middle Aged. Spondylitis, Ankylosing / drug therapy. Synovitis / drug therapy

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  • (PMID = 11455681.001).
  • [ISSN] 0004-4172
  • [Journal-full-title] Arzneimittel-Forschung
  • [ISO-abbreviation] Arzneimittelforschung
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 60GCX7Y6BH / Flufenamic Acid; KZF0XM66JC / etofenamate
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21. |......... 2%  Rosenthal M: [The iontophoresis with optidase and thiomucase in the treatment of rheumatic soft tissue disorders and osteoarthrosis (author's transl)]. Schweiz Rundsch Med Prax; 1979 Jul 3;68(27):892-4
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  • [Title] [The iontophoresis with optidase and thiomucase in the treatment of rheumatic soft tissue disorders and osteoarthrosis (author's transl)].
  • [Transliterated title] Die Iontophorese mit Optidase und Thiomucase bei der Behandlung rheumatischer Affektionen.
  • [MeSH-major] Catalase / administration & dosage. Glucuronidase / administration & dosage. Lyases / administration & dosage. Rheumatic Diseases / drug therapy
  • [MeSH-minor] Glycosaminoglycans. Humans. Iontophoresis

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  • (PMID = 157481.001).
  • [ISSN] 1013-2058
  • [Journal-full-title] Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis
  • [ISO-abbreviation] Schweiz. Rundsch. Med. Prax.
  • [Language] ger
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] SWITZERLAND
  • [Chemical-registry-number] 0 / Glycosaminoglycans; EC 1.11.1.6 / Catalase; EC 3.2.1.31 / Glucuronidase; EC 4.- / Lyases
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22. |......... 2%  Odebiyi DO, Adigun OT, Kehinde MO: Effect of sodium salicylate iontophoresis in the management of hip pain in patients with sickle cell disease. Nig Q J Hosp Med; 2007 Apr-Jun;17(2):82-6
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  • [Title] Effect of sodium salicylate iontophoresis in the management of hip pain in patients with sickle cell disease.
  • BACKGROUND: Iotophoresis is a means of delivering drugs across the skin for the management of a variety of conditions, most often for localized inflammation and pain.
  • It is becoming popular as an alternative to oral and injection delivery system because it is non-invasive, non-traumatic, and painless and also because of its specific delivery system.
  • OBJECTIVE: The objective of this study was to determine the effectiveness of sodium salicylate iontophoresis in the management of hip pain in patient with sickle cell disorders (SCD).
  • METHOD: The participants for this study were 20 patients with SCD, their ages ranged from 15-30 years.
  • In addition sodium salicylate iontophoresis was giving to the affected hip of the participants in the study group using a galvanic current machine.
  • Pain intensity and range of motion at the hip joint were assessed at the beginning and after 10 treatment sessions.
  • CONCLUSION: It was concluded that sodium salicylate iontophoresis was effective in the management of hip pain in patients with SCD.
  • [MeSH-major] Anemia, Sickle Cell / complications. Anti-Inflammatory Agents, Non-Steroidal / administration & dosage. Arthralgia / drug therapy. Hip Joint / drug effects. Sodium Salicylate / administration & dosage
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Iontophoresis. Male. Pain Measurement. Range of Motion, Articular. Treatment Outcome

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  • (PMID = 18318099.001).
  • [ISSN] 0189-2657
  • [Journal-full-title] Nigerian quarterly journal of hospital medicine
  • [ISO-abbreviation] Nig Q J Hosp Med
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; WIQ1H85SYP / Sodium Salicylate
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23. |......... 2%  Schiffman EL, Braun BL, Lindgren BR: Temporomandibular joint iontophoresis: a double-blind randomized clinical trial. J Orofac Pain; 1996;10(2):157-65
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  • [Title] Temporomandibular joint iontophoresis: a double-blind randomized clinical trial.
  • This double-blind study evaluated the short-term effect of iontophoretic delivery of dexamethasone on the signs and symptoms of temporomandibular disorders in patients who had concurrent temporomandibular joint disc displacement without reduction and capsulitis.
  • Twenty-seven patients with this clinical diagnosis were randomized to one of three groups: treatment group (dexamethasone sodium phosphate and lidocaine hydrochloride); control group (lidocaine hydrochloride); and placebo group (pH-buffered saline).
  • Pretreatment and posttreatment data included items to calculate Helkimo's Anamnestic Dysfunction index, Helkimo's Clinical Dysfunction index, the Symptom Severity Index, and the Craniomandibular Index (CMI).
  • The CMI is composed of the Dysfunction index (DI) and Muscle index.
  • Posttreatment, the treatment group had an increased mean maximal active mandibular opening of 6 mm (P = .02), increased mean lateral excursion of 1.2 mm to the noninvolved side (P = .05), and reduced mean DI scores of 0.51 to 0.39 (P = .01); no statistically significant decrease in pain symptoms was reported.
  • Analysis of variance showed a significant difference in the DI scores (P = .04) between groups from pretreatment to posttreatment, with the treatment group showing the greatest improvement in the DI scores relative to the other two groups.
  • No other questionnaire items, exam items, or resultant indexes showed changes in any of the groups at P < or = .05.
  • These results suggest that iontophoretic delivery of dexamethasone and lidocaine was effective in improving mandibular function, but not in reducing pain, in temporomandibular disorders patients who had concurrent temporomandibular joint capsulitis and disc displacement without reduction.
  • [MeSH-major] Anti-Inflammatory Agents / therapeutic use. Dexamethasone / therapeutic use. Iontophoresis. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Analysis of Variance. Anesthetics, Local / administration & dosage. Dislocations / drug therapy. Double-Blind Method. Female. Humans. Lidocaine / administration & dosage. Male. Middle Aged. Patient Satisfaction. Questionnaires. Severity of Illness Index. Statistics, Nonparametric. Synovitis / drug therapy

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  • (PMID = 9133860.001).
  • [ISSN] 1064-6655
  • [Journal-full-title] Journal of orofacial pain
  • [ISO-abbreviation] J Orofac Pain
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Anesthetics, Local; 0 / Anti-Inflammatory Agents; 7S5I7G3JQL / Dexamethasone; 98PI200987 / Lidocaine
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24. |......... 2%  Pavelka K Jr, Pavelka K Sr, Svarcova J, Vácha J, Trnavský K: [Can one increase the analgesic effect of Mobilisin ointment by iontophoresis? Placebo controlled triple cross-over double-blind study]. Z Rheumatol; 1988 Jul-Aug;47(4):233-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Can one increase the analgesic effect of Mobilisin ointment by iontophoresis? Placebo controlled triple cross-over double-blind study].
  • [Transliterated title] Kann man die analgetische Wirkung der Mobilisin-Salbe durch die Iontophorese verstärken? Plazebokontrollierte Dreifach-cross-over-Doppelblindstudie.
  • In a double-blind, three-way crossover trial, with placebo controls on 41 patients with inflammatory rheumatic disorders (mono- or oligoarticular forms), the analgesic action of Mobilisin ointment, with or without iontophoresis, was significantly stronger than after iontophoresis alone or after placebo.
  • Iontophoresis did not potentiate the analgesic properties of Mobilisin.
  • The duration of analgesic effect after Mobilisin procedures was 6.5 h on average, which was significantly longer than after iontophoresis alone or after placebo.
  • [MeSH-major] Arthritis, Rheumatoid / drug therapy. Flufenamic Acid / administration & dosage. Osteoarthritis / drug therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Clinical Trials as Topic. Double-Blind Method. Female. Humans. Iontophoresis. Male. Middle Aged. Ointments. Pain Measurement. Random Allocation

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  • (PMID = 3055745.001).
  • [ISSN] 0340-1855
  • [Journal-full-title] Zeitschrift für Rheumatologie
  • [ISO-abbreviation] Z Rheumatol
  • [Language] ger
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] GERMANY, WEST
  • [Chemical-registry-number] 0 / Ointments; 60GCX7Y6BH / Flufenamic Acid
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25. |......... 2%  Ulrych I: [Optidase in the treatment of arthrosis by intramuscular injections and iontophoresis (author's transl)]. Schweiz Rundsch Med Prax; 1979 May 8;68(19):617-9
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  • [Title] [Optidase in the treatment of arthrosis by intramuscular injections and iontophoresis (author's transl)].
  • [MeSH-major] Arthritis / drug therapy. Catalase / administration & dosage
  • [MeSH-minor] Clinical Trials as Topic. Drug Evaluation. Humans. Injections, Intramuscular. Iontophoresis. Time Factors

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  • (PMID = 377272.001).
  • [ISSN] 1013-2058
  • [Journal-full-title] Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis
  • [ISO-abbreviation] Schweiz. Rundsch. Med. Prax.
  • [Language] ger
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] SWITZERLAND
  • [Chemical-registry-number] EC 1.11.1.6 / Catalase
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26. |......... 2%  Onkelinx, Gritten, Ruhwiedel: [Enzymes and iontophoresis]. Acta Belg Med Phys; 1984 Jul-Sep;7(3):101-6
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  • [Title] [Enzymes and iontophoresis].
  • [MeSH-major] Connective Tissue Diseases / therapy. Enzymes / administration & dosage. Iontophoresis
  • [MeSH-minor] Cellulitis / therapy. Humans. Joint Diseases / therapy. Lymphedema / therapy. Male. Penile Induration / therapy

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  • (PMID = 6240174.001).
  • [ISSN] 0771-5684
  • [Journal-full-title] Acta Belgica. Medica physica : organe officiel de la Société royale belge de médecine physique et de réhabilitation
  • [ISO-abbreviation] Acta Belg Med Phys
  • [Language] fre
  • [Publication-type] Journal Article
  • [Publication-country] BELGIUM
  • [Chemical-registry-number] 0 / Enzymes
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27. |......... 2%  LANDA BACALLAO MA, DE DIEGO CABALLERO A: [Iontophoresis in the treatment of acute subdeltoid bursitis]. Med Lat; 1949 Jul-Dec;8(3-4):181-7
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  • [Title] [Iontophoresis in the treatment of acute subdeltoid bursitis].
  • [Transliterated title] La iontoforesis en el tratamiento de las bursitis agudas subdeltoideas.
  • [MeSH-major] Bursitis. Iontophoresis

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  • (PMID = 15400699.001).
  • [Journal-full-title] Medicina latina; revista médica de colaboración científica
  • [ISO-abbreviation] Med Lat
  • [Language] spa
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Other-IDs] CLML/ 5018:576e:3:7
  • [Keywords] NLM ; BURSITIS (major topic) / IONTOPHORESIS (major topic)
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28. |......... 2%  Michalak KA, Khoo PP, Yates PJ, Day RE, Wood DJ: Iontophoresed segmental allografts in revision arthroplasty for infection. J Bone Joint Surg Br; 2006 Nov;88(11):1430-7
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  • [Title] Iontophoresed segmental allografts in revision arthroplasty for infection.
  • We describe 12 two-stage revisions for infection in which segmental allografts were loaded with antibiotics using iontophoresis, a technique using an electrical potential to drive ionised antibiotics into cortical bone.
  • Iontophoresis produced high levels of antibiotic in the allograft, which eluted into the surrounding tissues.
  • None of the 12 patients who had two-stage revision with iontophoresed allografts had further infection after a mean period of 47 months (14 to 78).
  • [MeSH-major] Anti-Infective Agents / administration & dosage. Arthroplasty, Replacement. Iontophoresis / methods. Surgical Wound Infection / drug therapy
  • [MeSH-minor] Aged. Aged, 80 and over. Arthroplasty, Replacement, Hip. Arthroplasty, Replacement, Knee. Female. Humans. Male. Middle Aged. Osteoarthritis, Hip / surgery. Osteoarthritis, Knee / surgery. Postoperative Complications. Recurrence. Reoperation. Treatment Outcome

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  • (PMID = 17075085.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Infective Agents
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29. |......... 2%  Majwer K, Swider M: [Results of treatment with ionophoresis of posttraumatic changes of temporomandibular joints with an apparatus of own design]. Protet Stomatol; 1989 Jul-Dec;39(4-6):172-6
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  • [Title] [Results of treatment with ionophoresis of posttraumatic changes of temporomandibular joints with an apparatus of own design].
  • [Transliterated title] Wyniki leczenia jonoforeza zmian pourazowych stawów skroniowozuchwowych za pomoca aparatu własnego pomysłu.
  • The authors used ionophoresis applied with an apparatus of own design in 32 patients with posttraumatic changes in the temporomandibular joints.
  • The apparatus of own design was applied also for analgesia for operations on the middle ear through the external meatus, and in the treatment of ear buzzing and otalgia of unknown origin.
  • [MeSH-major] Iontophoresis / instrumentation. Temporomandibular Joint / injuries. Temporomandibular Joint Disorders / drug therapy

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  • (PMID = 2641160.001).
  • [ISSN] 0033-1783
  • [Journal-full-title] Protetyka stomatologiczna
  • [ISO-abbreviation] Protet Stomatol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] POLAND
  • [Chemical-registry-number] 98PI200987 / Lidocaine; WI4X0X7BPJ / Hydrocortisone
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30. |......... 2%  Chantraine A, Salmon A, Gustin R, Loix JM, Albassir R: [Current perspectives of iontophoresis]. J Belge Rhumatol Med Phys; 1971 Sep-Oct;26(5):251-6
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  • [Title] [Current perspectives of iontophoresis].
  • [Transliterated title] Perspectives actuelles en iontrophorèse.
  • [MeSH-major] Hydroxamic Acids / administration & dosage. Iontophoresis
  • [MeSH-minor] Analgesics. Anti-Inflammatory Agents. Joint Diseases / drug therapy. Phenylacetates

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  • (PMID = 5146629.001).
  • [ISSN] 0021-7654
  • [Journal-full-title] Journal belge de rhumatologie et de médecine physique = Belgisch tijdschrift voor reumatologie en fysische geneeskunde
  • [ISO-abbreviation] J Belge Rhumatol Med Phys
  • [Language] fre
  • [Publication-type] Journal Article
  • [Publication-country] BELGIUM
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents; 0 / Hydroxamic Acids; 0 / Phenylacetates
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31. |......... 2%  Boone DC: Hyaluronidase iontophoresis. Phys Ther; 1969 Feb;49(2):139-45
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  • [Title] Hyaluronidase iontophoresis.
  • [MeSH-major] Hemarthrosis / therapy. Hyaluronic Acid / administration & dosage. Iontophoresis

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  • (PMID = 5787943.001).
  • [ISSN] 0031-9023
  • [Journal-full-title] Physical therapy
  • [ISO-abbreviation] Phys Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 9004-61-9 / Hyaluronic Acid
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32. |......... 2%  Furto ES, Cleland JA, Whitman JM, Olson KA: Manual physical therapy interventions and exercise for patients with temporomandibular disorders. Cranio; 2006 Oct;24(4):283-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Manual physical therapy interventions and exercise for patients with temporomandibular disorders.
  • The purpose of this study was to investigate the outcome of a series of consecutive patients with temporomandibular disorder (TMD) who were treated with manual physical therapy interventions and exercise.
  • Consecutive patients with the clinical presentation of TMD completed several self-report measures and underwent a standardized historical and physical examination.
  • Following the examination, patients received a multimodal treatment approach incorporating manual physical therapy and exercise.
  • All self-report questionnaires were completed at a 2-week follow-up.
  • The mean TMD Disability Index scores were 32.1% (15.4%) at baseline and 18.3% (12.5%) at the 2-week follow-up, representing an improvement of 13.9% (CI: 8.2%, 19.5%) (p < 0.05).
  • These results suggest that patients with TMD who are treated with a rehabilitation program including manual physical therapy interventions plus exercise, with or without iontophoresis with dexamethasone, can demonstrate clinically meaningful improvements in disability and overall perceived change in a relatively short period of time.
  • [MeSH-major] Facial Pain / therapy. Iontophoresis. Physical Therapy Modalities. Temporomandibular Joint Disorders / therapy
  • [MeSH-minor] Anti-Inflammatory Agents / therapeutic use. Combined Modality Therapy. Confidence Intervals. Dexamethasone / therapeutic use. Disability Evaluation. Exercise Therapy. Female. Humans. Male. Middle Aged. Pilot Projects. Questionnaires. Treatment Outcome

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  • (PMID = 17086858.001).
  • [ISSN] 0886-9634
  • [Journal-full-title] Cranio : the journal of craniomandibular practice
  • [ISO-abbreviation] Cranio
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 7S5I7G3JQL / Dexamethasone
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33. |......... 2%  Aaron C, Quesnel MJ: [Use of Celestene by ionization in the treatment of rheumatic diseases]. Sem Hop; 1978 Oct 18-25;54(33-36):1091-4
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  • [Title] [Use of Celestene by ionization in the treatment of rheumatic diseases].
  • [Transliterated title] L'utilisation du célestène en ionisation dans le traitement des affections rhumatologiques.
  • The ionization technique is recalled as: nature of the current, generator, electrodes, methods, as well as the protocol.
  • Patients suffered mostly from rheumatologic diseases in particular scapulohumeral periarthritis, arthrosis, epicondylitis and abarticular syndromes, often long-standing and resistant to current therapeutics.
  • This serie also comprises 15 Dupuytren's contractures and La Peyronie's diseases.
  • [MeSH-major] Betamethasone / administration & dosage. Dupuytren Contracture / drug therapy. Joint Diseases / drug therapy. Penile Induration / drug therapy. Rheumatic Diseases / drug therapy
  • [MeSH-minor] Drug Evaluation. Female. Humans. Iontophoresis. Male. Osteoarthritis / drug therapy. Periarthritis / drug therapy

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  • (PMID = 220721.001).
  • [Journal-full-title] La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
  • [ISO-abbreviation] Sem Hop
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] FRANCE
  • [Chemical-registry-number] 9842X06Q6M / Betamethasone
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34. |......... 2%  Krawczyk-Wasielewska A, Kuncewicz E, Sobieska M, Samborski W: [Assess of patients' functional condition with rheumatoid arthritis before and after physical therapy treatment]. Chir Narzadow Ruchu Ortop Pol; 2009 Nov-Dec;74(6):361-6
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  • [Title] [Assess of patients' functional condition with rheumatoid arthritis before and after physical therapy treatment].
  • The aim of this study was to assess the impact of duration of disease and age on the functional condition of patients and also healing effectiveness in different duration of disease and age.
  • MATERIAL AND METHODS: The study involved 31 patients with rheumatoid arthritis aged 40-70 years, with duration of disease 5-20 years.
  • In this group was used following physical therapy technique: cryotherapy, ultrasound therapy, laser therapy, electrical stimulation TENS, iontophoresis, diadynamic and magnetic therapy.
  • Before and after the treatment motor capacity was estimated using Health Assessment Questionnaire (HAQ).
  • RESULTS: The presented results indicate improvement of measured parameters and increasement of patients independence after therapy, especially with duration of disease 5-10 years aged 60-70 years.
  • CONCLUSIONS: Susceptibility of anti pain treatment using physical therapy increase with increasing duration of disease.
  • Therapy influence on functional condition of patient decreasing with duration of disease.
  • [MeSH-major] Arthritis, Rheumatoid / therapy. Cryotherapy / methods. Iontophoresis / methods. Laser Therapy / methods. Physical Therapy Modalities. Severity of Illness Index
  • [MeSH-minor] Adult. Age Factors. Aged. Female. Follow-Up Studies. Humans. Magnetic Field Therapy / methods. Male. Middle Aged. Pain Measurement. Poland. Quality of Life. Range of Motion, Articular. Transcutaneous Electric Nerve Stimulation / methods. Treatment Outcome. Ultrasonic Therapy / methods


35. |......... 2%  de Bruin ED, Mangold S, Menzi C: [Evidence based evaluation of conservative treatment options for patellar tendinitis syndromes]. Sportverletz Sportschaden; 2003 Dec;17(4):165-70
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  • [Title] [Evidence based evaluation of conservative treatment options for patellar tendinitis syndromes].
  • [Transliterated title] Evidenzbasierte Beurteilung der konservativen Behandlungsmöglichkeiten des Patellaspitzensyndroms.
  • There is no consensus about conservative treatment strategies for this condition.
  • METHODS: With the help of the evidence-based medicine method it is estimated whether conservative treatment is appropriate for treating pain in this condition.
  • RESULTS: 5 specialist articles that matched the clinical question were found in medical databases.
  • The evaluation showed that physiotherapeutic treatment of pain in combination with additional iontophoresis is more promising than physiotherapy alone.
  • DISCUSSION: Current evidence suggests that traditional physiotherapy should be combined with additional therapeutic treatment.
  • [MeSH-major] Arthralgia / rehabilitation. Cumulative Trauma Disorders / rehabilitation. Evidence-Based Medicine / methods. Iontophoresis / methods. Palliative Care / methods. Patella / injuries. Physical Therapy Modalities / methods. Tendinopathy / rehabilitation
  • [MeSH-minor] Athletic Injuries / complications. Athletic Injuries / rehabilitation. Athletic Injuries / therapy. Clinical Trials as Topic. Combined Modality Therapy / methods. Knee Injuries / complications. Knee Injuries / rehabilitation. Knee Injuries / therapy. Treatment Outcome

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  • (PMID = 14666432.001).
  • [ISSN] 0932-0555
  • [Journal-full-title] Sportverletzung Sportschaden : Organ der Gesellschaft für Orthopädisch-Traumatologische Sportmedizin
  • [ISO-abbreviation] Sportverletz Sportschaden
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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36. |......... 1%  Netto HN: [Clinical experience using phenylbutazone ointment and iontophoresis]. Hospital (Rio J); 1968 Aug;74(2):527-31
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  • [Title] [Clinical experience using phenylbutazone ointment and iontophoresis].
  • [Transliterated title] Experiência clínica com a pomada de fenilbutazona e iontoforese.
  • [MeSH-major] Arthritis / drug therapy. Iontophoresis. Muscular Diseases / drug therapy. Phenylbutazone / administration & dosage

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  • (PMID = 5308678.001).
  • [ISSN] 0018-5469
  • [Journal-full-title] Hospital (Rio de Janeiro, Brazil)
  • [ISO-abbreviation] Hospital (Rio J)
  • [Language] por
  • [Publication-type] Journal Article
  • [Publication-country] BRAZIL
  • [Chemical-registry-number] 0 / Ointments; GN5P7K3T8S / Phenylbutazone
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37. |......... 1%  BOFFANO M: [Salicylic iontophoresis in arthralgias, with special reference to painful syndrome of the lumbar region]. Minerva Fisioter Radiobiol; 1961 Sep-Oct;6:291-305
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  • [Title] [Salicylic iontophoresis in arthralgias, with special reference to painful syndrome of the lumbar region].
  • [MeSH-major] Disease. Iontophoresis. Joint Diseases. Lumbosacral Region. Salicylates / therapy

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  • (PMID = 13870526.001).
  • [Journal-full-title] Minerva fisioterapica e radiobiologica
  • [ISO-abbreviation] Minerva Fisioter Radiobiol
  • [Language] ita
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Chemical-registry-number] 0 / Salicylates
  • [Keywords] NLM ; IONTOPHORESIS (major topic) / JOINTS/diseases (major topic) / LUMBOSACRAL REGION/diseases (major topic) / SALICYLATES/therapy (major topic)
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38. |......... 1%  Guzhvenko VM, Perepelkina NV: [Experience in using ultrasonic and laser therapy in surgical diseases]. Lik Sprava; 1997 Jul-Aug;(4):141-3
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  • [Title] [Experience in using ultrasonic and laser therapy in surgical diseases].
  • Experience is presented gained with the use of ultratonotherapy, low-intensity laser radiation of infrared actions, and a number of drug electrophoreses in the treatment of 358 surgical patients over 1994-1996.
  • A complex of combinations of different techniques common in physiotherapy has been designed with those of drug therapy during different phases of surgical disorders.
  • Methods and complexes of the therapy treatments to be administered are submitted together with relevant indications.
  • The proposed variants of complex physiotherapy make for earlier recovery, shorter treatment courses, longer remission.
  • [MeSH-major] Burns / rehabilitation. Hematoma / rehabilitation. Infrared Rays / therapeutic use. Joint Diseases / rehabilitation. Keloid / rehabilitation. Laser Therapy. Ultrasonic Therapy
  • [MeSH-minor] Combined Modality Therapy. Diathermy. Drug Therapy, Combination. Humans. Iontophoresis. Time Factors

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  • (PMID = 9471358.001).
  • [ISSN] 1019-5297
  • [Journal-full-title] Likars'ka sprava / Ministerstvo okhorony zdorov'ia Ukraïny
  • [ISO-abbreviation] Lik. Sprava
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] UKRAINE
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39. |......... 1%  Fomicheva TV, Soroka NF, Kobiatko LN: [The electrophoresis with sinusoidal modulated currents of copper ions from a dimexide solution in the combined treatment of patients with rheumatoid arthritis]. Vopr Kurortol Fizioter Lech Fiz Kult; 1991 Jan-Feb;(1):41-3
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  • [Title] [The electrophoresis with sinusoidal modulated currents of copper ions from a dimexide solution in the combined treatment of patients with rheumatoid arthritis].
  • [Transliterated title] Elektroforez ionov medi sinusoidal'nymi modulirovannymi tokami iz rastvora dimeksida v kompleksnom lechenii bol'nykh revmatoidnym artritom.
  • Sinusoidal modulated current electrophoresis of Cu ions from dimexide solution was compared to hydrocortisone ultraphonophoresis in combined treatment of rheumatoid arthritis patients.
  • High tolerance and therapeutic effect of combined action of sinusoidal modulated currents, Cu ions and dimexide permit advocation of this method as physical therapy for rheumatoid arthritis.
  • [MeSH-major] Arthritis, Rheumatoid / drug therapy. Copper / administration & dosage. Dimethyl Sulfoxide / administration & dosage. Iontophoresis / methods
  • [MeSH-minor] Combined Modality Therapy. Evaluation Studies as Topic. Female. Humans. Hydrocortisone / administration & dosage. Male. Phonophoresis. Solutions


40. |......... 1%  COYER AB: THE TREATMENT OF RHEUMATOID-TYPE ARTHRITIS OF THE HANDS BY CITRATE IONTOPHORESIS. Physiotherapy; 1964 Apr;50:127-8
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  • [Title] THE TREATMENT OF RHEUMATOID-TYPE ARTHRITIS OF THE HANDS BY CITRATE IONTOPHORESIS.
  • [MeSH-major] Arthritis, Rheumatoid. Citrates. Hand Injuries. Iontophoresis

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  • (PMID = 14139147.001).
  • [ISSN] 0031-9406
  • [Journal-full-title] Physiotherapy
  • [ISO-abbreviation] Physiotherapy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Citrates
  • [Keywords] NLM ; ARTHRITIS, RHEUMATOID (major topic) / CITRATES (major topic) / HAND INJURIES (major topic) / IONTOPHORESIS (major topic)
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41. |......... 1%  Krasil'nikov RG, Anokhin VN, Adla KhM: [A comparative assessment of the efficacy of thiophosphamide electrophoresis and ultrasound in the combined therapy of reactive arthritis]. Ter Arkh; 1991;63(5):72-4
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  • [Title] [A comparative assessment of the efficacy of thiophosphamide electrophoresis and ultrasound in the combined therapy of reactive arthritis].
  • The results of the treatment of patients suffering from rheumatoid arthritis with ultrasound (group I), thiophosphamide electrophoresis (group II), ultrasound and thiophosphamide (group III) and with medicamentous agents alone (group IV) are compared.
  • [MeSH-major] Arthritis, Infectious / therapy. Iontophoresis. Thiotepa / administration & dosage. Ultrasonic Therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Drug Evaluation. Evaluation Studies as Topic. Female. Humans. Male. Middle Aged. Remission Induction


42. |......... 1%  Saggini R, Zoppi M, Vecchiet F, Gatteschi L, Obletter G, Giamberardino MA: Comparison of electromotive drug administration with ketorolac or with placebo in patients with pain from rheumatic disease: a double-masked study. Clin Ther; 1996 Nov-Dec;18(6):1169-74
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  • [Title] Comparison of electromotive drug administration with ketorolac or with placebo in patients with pain from rheumatic disease: a double-masked study.
  • This study was undertaken to assess the efficacy of ketorolac compared with placebo when delivered by electromotive drug administration (EMDA) in patients with pain from rheumatic disease.
  • In EMDA, or iontophoresis, a low-intensity electric current is applied over the skin to deliver medication into body tissues.
  • Although EMDA has been used to treat patients with various diseases, controlled studies are lacking in patients with rheumatic disease.
  • They were divided randomly by a physician into 2 groups of 30 patients each for 5 sessions of active treatment (30 mg of ketorolac) or placebo (5 mL of normal saline).
  • Treatment took place every other day for 20 minutes.
  • Immediately before and after the five treatment sessions and 7 days after treatment ended, both patient and physician measured the degree of pain using a categoric scale (no pain, slight pain, intermediate pain, strong pain, and very strong pain) and evaluated pain intensity using the Scott and Huskisson Visual Analogue Scale (VAS).
  • Seven days after treatment ended, both physician and patient judged the result of treatment using a second categoric scale (no improvement or intermediate, good, or very good result).
  • Both ketorolac and placebo provided immediate, significant pain relief when delivered by EMDA, but only those patients receiving ketorolac experienced a further reduction in pain 7 days after treatment; those receiving placebo experienced a slight increase in pain.
  • No patient reported any adverse effects during treatment.
  • [MeSH-major] Analgesics, Non-Narcotic / administration & dosage. Arthralgia / drug therapy. Arthritis, Rheumatoid / complications. Iontophoresis / methods. Tolmetin / analogs & derivatives
  • [MeSH-minor] Administration, Cutaneous. Adult. Aged. Aged, 80 and over. Double-Blind Method. Drug Delivery Systems. Elbow Joint. Female. Follow-Up Studies. Humans. Ketorolac. Knee Joint. Male. Metatarsophalangeal Joint. Middle Aged. Pain Measurement. Periarthritis / complications. Tennis Elbow / complications. Treatment Outcome

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  • (PMID = 9001833.001).
  • [ISSN] 0149-2918
  • [Journal-full-title] Clinical therapeutics
  • [ISO-abbreviation] Clin Ther
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Analgesics, Non-Narcotic; D8K2JPN18B / Tolmetin; YZI5105V0L / Ketorolac
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43. |......... 1%  Motta AF, Borges Junior NG, da Fonseca JC, Tonussi CR: The antinociceptive effect of iontophoretic direct application of diclofenac to arthritic knee-joints of rats. Life Sci; 2003 Aug 29;73(15):1995-2004
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  • [Title] The antinociceptive effect of iontophoretic direct application of diclofenac to arthritic knee-joints of rats.
  • This study compared the antinociceptive effect produced by cathodic iontophoresis of sodium diclofenac close to an arthritic knee-joint in rats with that of systemic application.
  • Arthritic nocifensive incapacitation was induced by LPS (1 microg) injection into a knee-joint previously (72 h) primed with carrageenan (300 microg).
  • Diclofenac iontophoresis was performed by varying either the current density (0.1, 0.2, and 0.3 mA/cm2) or the duration of application (4, 10, 20 and 30 min) of a polyvinylpirrolydone-hydroxymethylcellulose gel containing 1% sodium diclofenac.
  • The ipsilateral iontophoresis (0.25 mA/cm2 x 10 min or 0.5 mA/cm2 x 4 min) of diclofenac produced an effect significantly greater than the same contralateral application (p<0.05).
  • In conclusion, our results suggest that the therapeutic effect depends on the current density but not on the application time, and also that the iontophoretic, direct application to the inflamed knee-joint enhances the therapeutic effect probably as a result of the direct delivery of the drug.
  • [MeSH-major] Analgesics / administration & dosage. Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Arthritis, Experimental / drug therapy. Diclofenac / therapeutic use. Iontophoresis. Pain / drug therapy
  • [MeSH-minor] Animals. Dose-Response Relationship, Drug. Escherichia coli / immunology. Hindlimb. Injections, Intra-Articular. Injections, Intraperitoneal. Joints. Lipopolysaccharides / administration & dosage. Lipopolysaccharides / pharmacology. Male. Pain Measurement. Rats. Rats, Wistar

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  • (PMID = 12899924.001).
  • [ISSN] 0024-3205
  • [Journal-full-title] Life sciences
  • [ISO-abbreviation] Life Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Analgesics; 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Lipopolysaccharides; 144O8QL0L1 / Diclofenac
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44. |......... 1%  Pramatarova A, Hamelin C: Electrophoresis of small DNA molecules in agaroses with different electroendosmotic properties. Appl Theor Electrophor; 1993;3(6):277-81
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  • [MeSH-minor] Electrophoresis, Agar Gel. Iontophoresis. Molecular Weight

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  • (PMID = 8199220.001).
  • [ISSN] 0954-6642
  • [Journal-full-title] Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society
  • [ISO-abbreviation] Appl. Theor. Electrophor.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 9007-49-2 / DNA
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45. |......... 1%  Crevenna R, Kéilani M, Wiesinger G, Nicolakis P, Quittan M, Fialka-Moser V: Calcific trochanteric bursitis: resolution of calcifications and clinical remission with non-invasive treatment. A case report. Wien Klin Wochenschr; 2002 May 15;114(8-9):345-8
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  • [Title] Calcific trochanteric bursitis: resolution of calcifications and clinical remission with non-invasive treatment. A case report.
  • Effective treatment is invasive, including infiltration therapy and surgical intervention.
  • The therapeutic effects of conservative treatment modalities have not been proven.
  • A 59-year-old woman presented at the department of physical medicine and rehabilitation with a 2-year history of pain in the right hip.
  • Physical examination revealed the clinical diagnosis of bursitis trochanterica.
  • The patient presented for conservative treatment in order to avoid surgical intervention for removing the calcification and the bursal sac.
  • A non-invasive treatment regimen including intensive pulsed ultrasound therapy, physiotherapy and iontophoresis was started.
  • The conservative treatment led to a remission of both, symptoms as well as radiographic findings, which revealed complete resolution of calcifications.
  • This case report shows that, in cases of calcific trochanteric bursitis (including those with extensive calcifications), a non-invasive conservative treatment regimen including intensive high-dosed pulsed ultrasound therapy should be attempted before more invasive treatment (injections, surgery) is considered.
  • [MeSH-minor] Combined Modality Therapy. Female. Humans. Iontophoresis. Middle Aged. Physical Therapy Modalities. Treatment Outcome. Ultrasonic Therapy

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  • (PMID = 12212371.001).
  • [ISSN] 0043-5325
  • [Journal-full-title] Wiener klinische Wochenschrift
  • [ISO-abbreviation] Wien. Klin. Wochenschr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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46. |......... 1%  Boykikeva SA: [The treatment of bursitis calcarea with ultrasonics and Novadren-iontophoresis]. Beitr Orthop Traumatol; 1970;17(8):490-1
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  • [Title] [The treatment of bursitis calcarea with ultrasonics and Novadren-iontophoresis].
  • [Transliterated title] Die Behandlung der Bursitis calcarea mit Ultraschall und Novadren-Iontophorese.
  • [MeSH-major] Amino Alcohols / administration & dosage. Bursitis / therapy. Iontophoresis. Ultrasonic Therapy

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  • (PMID = 5474771.001).
  • [ISSN] 0005-8149
  • [Journal-full-title] Beiträge zur Orthopädie und Traumatologie
  • [ISO-abbreviation] Beitr Orthop Traumatol
  • [Language] ger
  • [Publication-type] Journal Article
  • [Publication-country] GERMANY, EAST
  • [Chemical-registry-number] 0 / Amino Alcohols; 0 / Catechols
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47. |......... 1%  Georgiev GB: [Treatment of certain degenerative-dystrophic diseases of the joints by the electrophoresis of native commercial petroleum (clinical and experimental studies)]. Vopr Kurortol Fizioter Lech Fiz Kult; 1974 Mar;39(2):149-55
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  • [Title] [Treatment of certain degenerative-dystrophic diseases of the joints by the electrophoresis of native commercial petroleum (clinical and experimental studies)].
  • [Transliterated title] Lechenie nekotorykh degenerativno-distroficheskikh zabolevaniĭ sustavov élektroforezom nativnoĭ promyshlennoĭ neft'iu (kliniko-éksperimental'nye issledovaniia
  • [MeSH-major] Iontophoresis. Joint Diseases / drug therapy. Petroleum / therapeutic use
  • [MeSH-minor] Bulgaria. Clinical Trials as Topic. Female. Follow-Up Studies. Humans. Male. Membranes, Artificial. Microcirculation / drug effects. Osteoarthritis / drug therapy

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  • (PMID = 4599138.001).
  • [ISSN] 0042-8787
  • [Journal-full-title] Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
  • [ISO-abbreviation] Vopr Kurortol Fizioter Lech Fiz Kult
  • [Language] rus
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] 0 / Membranes, Artificial; 0 / Petroleum
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48. |......... 1%  Reid KI, Dionne RA, Sicard-Rosenbaum L, Lord D, Dubner RA: Evaluation of iontophoretically applied dexamethasone for painful pathologic temporomandibular joints. Oral Surg Oral Med Oral Pathol; 1994 Jun;77(6):605-9
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  • [Title] Evaluation of iontophoretically applied dexamethasone for painful pathologic temporomandibular joints.
  • The effects of iontophoretically applied dexamethasone in a lidocaine vehicle were compared with those of saline placebo in 53 patients with one of three diagnoses of painful temporomandibular joint pathologic conditions: disk displacement with reduction, disk displacement without reduction, and osteoarthritis.
  • A trend for pain relief was noted in the subgroup that received dexamethasone with a diagnosis of osteoarthritis.
  • These data suggest that iontophoretically applied dexamethasone is no more effective than saline placebo in providing pain relief in patients with temporomandibular joint pain.
  • [MeSH-major] Dexamethasone / administration & dosage. Facial Pain / drug therapy. Iontophoresis. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Adult. Analysis of Variance. Chronic Disease. Dislocations / drug therapy. Double-Blind Method. Female. Humans. Male. Osteoarthritis / drug therapy. Pain Measurement. Range of Motion, Articular

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  • (PMID = 8065724.001).
  • [ISSN] 0030-4220
  • [Journal-full-title] Oral surgery, oral medicine, and oral pathology
  • [ISO-abbreviation] Oral Surg. Oral Med. Oral Pathol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 7S5I7G3JQL / Dexamethasone
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49. |......... 1%  Ibadova GD, Khamrakulova VV, Lopatinskiĭ VV: [The laser-magnetic phoresis of ascorbic acid in the combined health-resort therapy of osteoarthrosis patients]. Vopr Kurortol Fizioter Lech Fiz Kult; 1996 Jul-Aug;(4):17-9
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  • [Title] [The laser-magnetic phoresis of ascorbic acid in the combined health-resort therapy of osteoarthrosis patients].
  • In vitro experiments demonstrate stability of ascorbic acid pH solution and a 1.5-fold increase in ascorbic acid mass-transfer through semipermeable membranes in exposure to laser radiation and magnetic field generated by the device Uzor.
  • Bioavailability of ascorbic acid was proved by adaptogenic and antioxidant effects of laser-magnetophoresis of 2% ascorbic acid solution applied to the affected joints in 79 patients with osteochondrosis.
  • [MeSH-major] Ascorbic Acid / administration & dosage. Health Resorts. Iontophoresis / methods. Laser Therapy. Magnetics / therapeutic use. Osteoarthritis / rehabilitation
  • [MeSH-minor] Combined Modality Therapy. Evaluation Studies as Topic. Humans. Lipid Peroxidation. Russia. Solutions

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  • (PMID = 8975469.001).
  • [ISSN] 0042-8787
  • [Journal-full-title] Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
  • [ISO-abbreviation] Vopr Kurortol Fizioter Lech Fiz Kult
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] RUSSIA
  • [Chemical-registry-number] 0 / Solutions; PQ6CK8PD0R / Ascorbic Acid
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50. |......... 1%  Shchekoldin PI, Kozlova LA, Budkar' LN: [A new method for treating rheumatoid arthritis patients by electrophoresis using mefenamic acid]. Vopr Kurortol Fizioter Lech Fiz Kult; 1992 Jul-Aug;(4):17-21
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  • The paper provides clinical and experimental reasoning for application of a new treatment for rheumatoid arthritis (RA) implying electrophoresis of an anti-inflammatory drug mefenamic acid from dimexide solution.
  • The best effect was shown in an inactive disease and in activity phases I and II in adjuvant use of the method.
  • [MeSH-major] Arthritis, Rheumatoid / drug therapy. Iontophoresis / methods. Mefenamic Acid / administration & dosage
  • [MeSH-minor] Adult. Animals. Chemistry, Physical. Dimethyl Sulfoxide / administration & dosage. Dimethyl Sulfoxide / chemistry. Drug Evaluation. Drug Evaluation, Preclinical. Female. Humans. Male. Middle Aged. Physicochemical Phenomena. Skin Absorption / drug effects. Solutions


51. |......... 1%  Mraz F, Wigdorowicz-Makowerowa N, Maslanka T, Panek H, Krzyszton E: [Differential diagnosis and therapy of painful forms of temporomandibular joint myoarthropathy]. Protet Stomatol; 1979 Sep-Oct;29(5):357-62
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  • [Title] [Differential diagnosis and therapy of painful forms of temporomandibular joint myoarthropathy].
  • [MeSH-major] Iontophoresis. Joint Diseases / therapy. Temporomandibular Joint
  • [MeSH-minor] Diagnosis, Differential. Humans

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  • (PMID = 298369.001).
  • [ISSN] 0033-1783
  • [Journal-full-title] Protetyka stomatologiczna
  • [ISO-abbreviation] Protet Stomatol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] POLAND
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52. |......... 1%  Zobnina GV, Ulashchik VS: [Experimental and clinical study of the electrophoresis of drugs with immunodepressive action]. Vopr Kurortol Fizioter Lech Fiz Kult; 1984 Jul-Aug;(4):6-9
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  • [Title] [Experimental and clinical study of the electrophoresis of drugs with immunodepressive action].
  • [MeSH-major] Immunosuppressive Agents / administration & dosage. Iontophoresis
  • [MeSH-minor] Arthritis, Rheumatoid / drug therapy. Chemistry, Physical. Drug Stability. Fluorouracil / administration & dosage. Humans. Lumbosacral Region. Osteochondritis / drug therapy. Physicochemical Phenomena. Prednisolone / administration & dosage. Skin Absorption / drug effects. Tegafur / administration & dosage

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  • (PMID = 6435310.001).
  • [ISSN] 0042-8787
  • [Journal-full-title] Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
  • [ISO-abbreviation] Vopr Kurortol Fizioter Lech Fiz Kult
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; In Vitro; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; 1548R74NSZ / Tegafur; 9PHQ9Y1OLM / Prednisolone; U3P01618RT / Fluorouracil
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53. |......... 1%  Préat V: [Drug and gene delivery using electrotransfer]. Ann Pharm Fr; 2001 Jul;59(4):239-44
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  • [Transliterated title] Administration de médicaments et de gènes par électrotransfert.
  • The use of a low intensity current (iontophoresis) and high voltage pulses (electroporation which permeabilizes lipid bilayers) has a potential for the administration of conventional and biotechnology-produced drugs.
  • Iontophoresis and electroporation enhance transdermal delivery of drugs, including peptides and oligonucleotides.
  • Electrochemotherapy, i.e., combination of a systemic or local delivery of a non-permeant cytostatic drug with electroporation, kills locally tumor cells.
  • Recently, it has been shown that the local injection of a plasmid before electroporation increases significantly gene transfection.
  • [MeSH-major] Drug Delivery Systems. Electroporation. Genetic Therapy / methods
  • [MeSH-minor] Animals. DNA / genetics. Humans. Iontophoresis

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  • (PMID = 11468578.001).
  • [ISSN] 0003-4509
  • [Journal-full-title] Annales pharmaceutiques françaises
  • [ISO-abbreviation] Ann Pharm Fr
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 9007-49-2 / DNA
  • [Number-of-references] 20
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54. |......... 1%  Braun BL: Treatment of an acute anterior disk displacement in the temporomandibular joint. A case report. Phys Ther; 1987 Aug;67(8):1234-6
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  • [Title] Treatment of an acute anterior disk displacement in the temporomandibular joint. A case report.
  • The purpose of this case report is to describe the effects of a home exercise program and iontophoretic delivery of an anti-inflammatory agent and an anesthetic in the treatment of a patient with an acute internal derangement of the temporomandibular joint (TMJ).
  • A 71-year-old woman was referred to physical therapy for treatment of an acute anterior displacement of the disk in the TMJ.
  • Clinical signs and symptoms were reduced after the first treatment and continued to abate during the course of treatment.
  • Six weeks after treatment, her jaw range of motion remained within normal limits.
  • [MeSH-major] Dexamethasone / analogs & derivatives. Lidocaine / administration & dosage. Physical Therapy Modalities / methods. Temporomandibular Joint Disorders / therapy
  • [MeSH-minor] Acute Disease. Aged. Female. Humans. Iontophoresis. Temporomandibular Joint / physiopathology


55. |......... 1%  Jain R, Jain E, Dass AG, Wickstrom O, Walter N, Atkinson PJ: Evaluation of transdermal steroids for trapeziometacarpal arthritis. J Hand Surg Am; 2010 Jun;35(6):921-7
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  • PURPOSE: One conservative treatment for trapeziometacarpal joint arthritis is the delivery of steroids transdermally.
  • It appears that the benefits of the treatment might be limited to short-term relief (approximately one week).
  • It was hypothesized that transdermal steroid delivery would yield short-term improvements for trapezial-metacarpal joint arthritis, although these improvements would not persist at later follow-up (3 or 6 months).
  • METHODS: Eighty-four consecutive trapeziometacarpal joints in 62 patients presenting to an orthopedic hand surgeon were randomized to receive either steroid delivery by iontophoresis or phonophoresis or placebo delivery via iontophoresis or phonophoresis.
  • The researchers and patients were blinded as to the treatment assignment.
  • Patients were evaluated before treatment and at 3 follow-up appointments.
  • Following subject recruitment, 17 joints discontinued the study due to joint discomfort, electing for other treatments.
  • Approximately half of the 67 subject joints opted for alternative treatment after the first or second follow-up; 34 subject joints completed all follow-up time points.
  • The strength for both iontophoresis groups tended to increase over time, whereas the phonophoresis groups tended to decline.
  • [MeSH-major] Arthritis / drug therapy. Glucocorticoids / administration & dosage. Wrist Joint
  • [MeSH-minor] Administration, Cutaneous. Aged. Double-Blind Method. Female. Hand Strength. Humans. Iontophoresis. Male. Middle Aged. Multivariate Analysis. Pain Measurement. Phonophoresis

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  • [Copyright] Copyright 2010 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20452733.001).
  • [ISSN] 1531-6564
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glucocorticoids
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56. |......... 1%  Datta D, Ferrell WR, Sturrock RD, Jadhav ST, Sattar N: Inflammatory suppression rapidly attenuates microvascular dysfunction in rheumatoid arthritis. Atherosclerosis; 2007 Jun;192(2):391-5
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  • [Title] Inflammatory suppression rapidly attenuates microvascular dysfunction in rheumatoid arthritis.
  • Rheumatoid arthritis (RA) is associated with greater risk of cardiovascular morbidity and mortality, the inflammatory component of RA being strongly linked to this excess risk.
  • Endothelial dysfunction is linked to atherosclerosis and has been demonstrated in larger vessels in RA.
  • In this pilot study, we determined for the first time whether skin microvascular function was impaired in patients with active RA and also determined its response to anti-inflammatory treatment.
  • This was assessed non-invasively using laser Doppler imaging combined with iontophoresis of the vasodilators acetylcholine (ACh, endothelium dependent) and sodium nitroprusside (SNP, endothelium independent) to the forearm.
  • Eight RA patients admitted for acute flare-ups were assessed before and following anti-inflammatory treatment.
  • Following treatment, as CRP and VAS decreased, vascular function improved for both ACh (P<0.00001) and SNP (P=0.001), this improvement being significantly greater for ACh (P<0.001).
  • Vascular dysfunction is evident in RA patients, even at the level of the cutaneous microcirculation, but improves as inflammation regresses.
  • Assessment of cutaneous vascular function may be a useful, non-invasive surrogate indicator of vascular risk in RA, inclusive of myocardial microvascular abnormalities.
  • [MeSH-major] Anti-Inflammatory Agents / therapeutic use. Arthritis, Rheumatoid / drug therapy. Microcirculation / drug effects
  • [MeSH-minor] Acetylcholine / diagnostic use. Aged. C-Reactive Protein / analysis. Female. Humans. Iontophoresis. Laser-Doppler Flowmetry. Male. Middle Aged. Nitroprusside / diagnostic use. Skin / blood supply

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  • (PMID = 16806231.001).
  • [ISSN] 0021-9150
  • [Journal-full-title] Atherosclerosis
  • [ISO-abbreviation] Atherosclerosis
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 169D1260KM / Nitroprusside; 9007-41-4 / C-Reactive Protein; N9YNS0M02X / Acetylcholine
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57. |......... 1%  Ivshina O: [Hypnotherapy of acute generalized allergic reaction to electrophoresis]. Vopr Kurortol Fizioter Lech Fiz Kult; 1966 May-Jun;31(3):271-2
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  • [MeSH-major] Hypersensitivity, Immediate. Hypnosis. Iontophoresis / adverse effects
  • [MeSH-minor] Adult. Arthritis, Rheumatoid / therapy. Balneology. Calcium Chloride / therapeutic use. Female. Humans. Polyradiculopathy / therapy

  • HSDB. structure - CALCIUM CHLORIDE.
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  • (PMID = 5993382.001).
  • [ISSN] 0042-8787
  • [Journal-full-title] Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
  • [ISO-abbreviation] Vopr Kurortol Fizioter Lech Fiz Kult
  • [Language] rus
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] M4I0D6VV5M / Calcium Chloride
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58. |......... 1%  Ozgocmen S, Kiris A, Ardicoglu O, Kocakoc E, Kaya A: Glucocorticoid iontophoresis for Achilles tendon enthesitis in ankylosing spondylitis: significant response documented by power Doppler ultrasound. Rheumatol Int; 2005 Mar;25(2):158-60
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  • [Title] Glucocorticoid iontophoresis for Achilles tendon enthesitis in ankylosing spondylitis: significant response documented by power Doppler ultrasound.
  • [MeSH-major] Achilles Tendon / drug effects. Achilles Tendon / ultrasonography. Glucocorticoids / administration & dosage. Rheumatic Diseases / drug therapy. Spondylitis, Ankylosing / complications
  • [MeSH-minor] Adult. Humans. Iontophoresis. Male. Ultrasonography, Doppler


59. |......... 1%  van den Bergh FA, Martens A: [Diagnosis of cystic fibrosis; simple genotyping to rule out the disease preferable to starting with the sweat test]. Ned Tijdschr Geneeskd; 2003 May 24;147(21):1001-5
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  • [Title] [Diagnosis of cystic fibrosis; simple genotyping to rule out the disease preferable to starting with the sweat test].
  • [Transliterated title] Diagnostiek van cystische fibrose; liever eenvoudige genotypering om de ziekte uit te sluiten dan starten met de zweettest.
  • If CF is suspected, the sweat test (following pilocarpine iontophoresis) is usually performed first to confirm or rule out the diagnosis of CF.
  • Because of the high negative predictive value of DNA testing, in combination with its speed, reliability and convenience for the patient, starting the diagnostic work-up for CF with DNA testing can be justified in hospitals which possess the laboratory facilities for this type of test.
  • [MeSH-major] Cystic Fibrosis / diagnosis. DNA / analysis
  • [MeSH-minor] Genotype. Humans. Iontophoresis. Mutation / genetics. Pancreatic Function Tests. Pilocarpine / diagnostic use. Polymerase Chain Reaction. Predictive Value of Tests. Sweat / chemistry

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  • (PMID = 12811969.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 01MI4Q9DI3 / Pilocarpine; 9007-49-2 / DNA
  • [Number-of-references] 28
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60. |......... 1%  Mally MI: Genetic engineering of human lymphocytes for the production of monoclonal antibodies. Hum Antibodies Hybridomas; 1990;1(1):27-33
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  • [MeSH-major] Antibodies, Monoclonal / biosynthesis. B-Lymphocytes / immunology. Cloning, Molecular / methods. Genes, Immunoglobulin. Iontophoresis / methods. Recombinant Proteins / biosynthesis

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  • (PMID = 1966472.001).
  • [ISSN] 0956-960X
  • [Journal-full-title] Human antibodies and hybridomas
  • [ISO-abbreviation] Hum. Antibodies Hybridomas
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Recombinant Proteins; 9007-49-2 / DNA
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61. |......... 1%  Babaskin DV, Chuntomov PN, Pozhidaev IA, Mosolova EG, Ter-Ovakimian AV: [The application of sinusoidal modulated current electrophoresis of a phytopreparation for the rehabilitation of patients with knee joint osteoarthrosis]. Vopr Kurortol Fizioter Lech Fiz Kult; 2011 Nov-Dec;(6):24-8
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  • [Title] [The application of sinusoidal modulated current electrophoresis of a phytopreparation for the rehabilitation of patients with knee joint osteoarthrosis].
  • The objective of the present comparative study was to estimate the efficacy of the rehabilitative treatment of the patients presenting with knee joint osteoarthrosis using sinusoidal modulated current electrophoresis of a phytopreparation.
  • It was shown that the combination of phyto- and electrotherapies allows to more efficaciously alleviate pain in the knee joint and improve its function than pharmacotherapy or its combination with amplipulse therapy.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Osteoarthritis, Knee / rehabilitation. Phytotherapy / methods. Plant Preparations / therapeutic use
  • [MeSH-minor] Combined Modality Therapy. Electric Stimulation Therapy. Female. Humans. Iontophoresis. Male. Middle Aged. Treatment Outcome

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  • (PMID = 22403951.001).
  • [ISSN] 0042-8787
  • [Journal-full-title] Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
  • [ISO-abbreviation] Vopr Kurortol Fizioter Lech Fiz Kult
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Plant Preparations
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62. |......... 1%  Dougherty PM, Sluka KA, Sorkin LS, Westlund KN, Willis WD: Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids. Brain Res Brain Res Rev; 1992 Jan-Apr;17(1):1-13
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  • The results demonstrate that the responses of STT neurons to mechanical stimuli and to iontophoretically applied excitatory amino acids (EAAs), particularly those acting at non-N-methyl-D-aspartate (non-NMDA) receptors, become enhanced during the development of inflammation produced by intra-articular injection of kaolin and carrageenan.
  • [MeSH-minor] Acute Disease. Afferent Pathways / drug effects. Afferent Pathways / physiology. Animals. Biomechanical Phenomena. Electric Stimulation. Iontophoresis. Macaca fascicularis. Neural Pathways / drug effects. Neural Pathways / physiology

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  • (PMID = 1638273.001).
  • [Journal-full-title] Brain research. Brain research reviews
  • [ISO-abbreviation] Brain Res. Brain Res. Rev.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / NS01445; United States / NINDS NIH HHS / NS / NS09743; United States / NINDS NIH HHS / NS / NS11255; etc
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] NETHERLANDS
  • [Chemical-registry-number] 0 / Amino Acids
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63. |......... 1%  MARTENS AS: [USE OF HYDROCORTISONE PHONOPHORESIS IN THE TREATMENT OF JOINT INJURIES AND THEIR SEQUELAE IN ATHLETES]. Ortop Travmatol Protez; 1965 Apr;26:69-71
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  • [Title] [USE OF HYDROCORTISONE PHONOPHORESIS IN THE TREATMENT OF JOINT INJURIES AND THEIR SEQUELAE IN ATHLETES].
  • [Transliterated title] O PRIMENENII FONOFOREZA GIDROKORTZONA PRI LECHENII POVREZHDENI I SUSTAVOV I IKH POSLEDSTVI I U SPORTSMENOV.
  • [MeSH-major] Hydrocortisone. Iontophoresis. Joint Diseases. Sports Medicine

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  • HSDB. structure - HYDROCORTISONE.
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  • (PMID = 14345102.001).
  • [ISSN] 0030-5987
  • [Journal-full-title] Ortopediia travmatologiia i protezirovanie
  • [ISO-abbreviation] Ortop Travmatol Protez
  • [Language] rus
  • [Publication-type] Journal Article
  • [Publication-country] RUSSIA
  • [Chemical-registry-number] WI4X0X7BPJ / Hydrocortisone
  • [Keywords] NLM ; HYDROCORTISONE, TOPICAL (major topic) / IONTOPHORESIS (major topic) / JOINT DISEASES (major topic) / SPORT MEDICINE (major topic)
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64. |......... 1%  Murray K: Nucleotide 'maps' of digests of deoxyribonucleic acid. Biochem J; 1970 Aug;118(5):831-41
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  • [MeSH-minor] Cellulose. DNA, Bacterial / analysis. DNA, Viral / analysis. Deoxyribonucleases. Iontophoresis. Phosphorus Isotopes

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  • (PMID = 5476726.001).
  • [ISSN] 0264-6021
  • [Journal-full-title] The Biochemical journal
  • [ISO-abbreviation] Biochem. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / DNA, Bacterial; 0 / DNA, Viral; 0 / Nucleotides; 0 / Phosphorus Isotopes; 9004-34-6 / Cellulose; 9007-49-2 / DNA; EC 3.1.- / Deoxyribonucleases
  • [Other-IDs] NLM/ PMC1179294
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65. |......... 1%  Swezey RL: Rheumatoid arthritis: the role of the kinder and gentler therapies. J Rheumatol Suppl; 1990 Nov;25:8-13
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  • The effects of heat, cold, and electrical stimulation on neurohumoral, inflammatory, and immunological mechanisms has been noted, although knowledge about their mode of action is lacking.
  • [MeSH-minor] Acupuncture Therapy. Braces. Exercise Therapy. Humans. Iontophoresis. Palliative Care. Phonophoresis. Quality of Life. Splints. Steroids / administration & dosage. Steroids / therapeutic use

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  • (PMID = 1703234.001).
  • [ISSN] 0380-0903
  • [Journal-full-title] The Journal of rheumatology. Supplement
  • [ISO-abbreviation] J Rheumatol Suppl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] CANADA
  • [Chemical-registry-number] 0 / Steroids
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66. |......... 1%  Perrin C, Ky TM, Hangen JF, Barthelme A: [Ionophoresis of the external auditory canal. Technic, indications]. J Fr Otorhinolaryngol Audiophonol Chir Maxillofac; 1983 Nov;32(9):538-40
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  • [MeSH-major] Analgesia / methods. Ear Canal. Earache / therapy. Iontophoresis
  • [MeSH-minor] Humans. Temporomandibular Joint Dysfunction Syndrome / therapy

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  • (PMID = 6228627.001).
  • [ISSN] 0398-9771
  • [Journal-full-title] Journal français d'oto-rhino-laryngologie; audiophonologie, chirurgie maxillo-faciale
  • [ISO-abbreviation] J Fr Otorhinolaryngol Audiophonol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Journal Article
  • [Publication-country] FRANCE
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67. |......... 1%  Hamdy O, Abou-Elenin K, LoGerfo FW, Horton ES, Veves A: Contribution of nerve-axon reflex-related vasodilation to the total skin vasodilation in diabetic patients with and without neuropathy. Diabetes Care; 2001 Feb;24(2):344-9
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  • RESEARCH DESIGN AND METHODS: The skin microcirculation was evaluated at the forearm level in 69 healthy subjects and 42 nonneuropathic diabetic patients and at the foot level in 27 healthy subjects and 101 diabetic patients (33 with neuropathy, 23 with Charcot arthropathy, 32 with peripheral vascular disease and neuropathy, and 13 without complications).
  • Two single-point laser probes were used to measure total and neurovascular vasodilation response to the iontophoresis of 1% acetylcholine, 1% sodium nitroprusside, and deionized water.
  • A significantly lower nonspecific nerve-axon-related vasodilation was observed during the iontophoresis of sodium nitroprusside, which does not specifically stimulate the C nociceptive fibers.
  • [MeSH-minor] Acetylcholine / administration & dosage. Acetylcholine / diagnostic use. Adult. Diabetic Angiopathies / physiopathology. Female. Foot. Forearm. Humans. Iontophoresis. Male. Middle Aged. Nitroprusside / administration & dosage. Nitroprusside / diagnostic use

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  • (PMID = 11213890.001).
  • [ISSN] 0149-5992
  • [Journal-full-title] Diabetes care
  • [ISO-abbreviation] Diabetes Care
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 169D1260KM / Nitroprusside; N9YNS0M02X / Acetylcholine
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68. |......... 1%  Gangarosa LP Sr, Mahan PE, Ciarlone AE: Pharmacologic management of temporomandibular joint disorders and chronic head and neck pain. Cranio; 1991 Oct;9(4):328-38
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  • [Title] Pharmacologic management of temporomandibular joint disorders and chronic head and neck pain.
  • The two cycles perpetuate each other because they have many interacting factors in common.
  • Drugs are useful either alone or to supplement other forms of therapy that can break the pain/spasm cycle, as well as the pain/inflammation cycle.
  • [MeSH-major] Analgesics / therapeutic use. Headache / drug therapy. Pain, Intractable / drug therapy. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Chronic Disease. Humans. Inflammation / complications. Inflammation / drug therapy. Iontophoresis. Muscle Spasticity / drug therapy. Neck Muscles / physiopathology. Placebo Effect

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  • (PMID = 1820833.001).
  • [ISSN] 0886-9634
  • [Journal-full-title] Cranio : the journal of craniomandibular practice
  • [ISO-abbreviation] Cranio
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Analgesics
  • [Number-of-references] 37
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69. |......... 1%  Murphy GJ: Physical medicine modalities and trigger point injections in the management of temporomandibular disorders and assessing treatment outcome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 1997 Jan;83(1):118-22
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  • [Title] Physical medicine modalities and trigger point injections in the management of temporomandibular disorders and assessing treatment outcome.
  • Temporomandibular disorders (TMDs) are principally musculoskeletal, orthopedic, and neurologic in nature.
  • The use of trigger point injections and physical medicine modalities has become commonplace in the management of TMDs.
  • These modalities have a long and successful history in the management of similar disorders in other areas of the body, and it is only natural that they would be included in the management of TMD as well.
  • [MeSH-major] Physical Therapy Modalities. Temporomandibular Joint Dysfunction Syndrome / therapy
  • [MeSH-minor] Electric Stimulation Therapy. Humans. Injections, Intramuscular. Iontophoresis. Manipulation, Orthopedic. Outcome Assessment (Health Care). Transcutaneous Electric Nerve Stimulation. Ultrasonic Therapy

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  • (PMID = 9007934.001).
  • [ISSN] 1079-2104
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] UNITED STATES
  • [Number-of-references] 79
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70. |......... 1%  van Eijk IC, Serné EH, Dijkmans BA, Smulders Y, Nurmohamed M: Microvascular function is preserved in newly diagnosed rheumatoid arthritis and low systemic inflammatory activity. Clin Rheumatol; 2011 Aug;30(8):1113-8
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  • [Title] Microvascular function is preserved in newly diagnosed rheumatoid arthritis and low systemic inflammatory activity.
  • Microvascular function has been linked to several risk factors for cardiovascular disease and may be affected in RA.
  • It is, however, presently unknown at what point in the disease course the abnormalities in microvascular function occur.
  • We determined whether microvascular function is already disturbed in early disease-modifying antirheumatic drugs (DMARD)-naive RA patients with low systemic inflammation.
  • Fifteen consecutive RA patients with a median symptom duration of 5 months, a C-reactive protein level of ≤20 mg/l and without a history of cardiovascular disease, and age 15 and sex-matched healthy controls were recruited.
  • Endothelium-dependent and endothelium-independent vasodilatation in skin was evaluated with laser Doppler fluxmetry after iontophoresis of acetylcholine and sodium nitroprusside, respectively.
  • Skin microvascular function is preserved in early, DMARD-naive RA patients with moderately active RA but low systemic inflammatory activity.
  • Both the extent of the systemic inflammation and disease duration, therefore, may be important determinants of microvascular dysfunction and subsequent increased risk for cardiovascular disease.
  • [MeSH-major] Arthritis, Rheumatoid / diagnosis. Inflammation / pathology. Microcirculation / physiology. Skin / blood supply
  • [MeSH-minor] Acetylcholine / diagnostic use. Blood Flow Velocity / physiology. C-Reactive Protein / analysis. Female. Humans. Iontophoresis. Male. Microscopy, Video / methods. Middle Aged. Nitroprusside / diagnostic use. Time Factors. Vasodilation / drug effects. Vasodilation / physiology. Vasodilator Agents / diagnostic use

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  • (PMID = 21484221.001).
  • [ISSN] 1434-9949
  • [Journal-full-title] Clinical rheumatology
  • [ISO-abbreviation] Clin. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Vasodilator Agents; 169D1260KM / Nitroprusside; 9007-41-4 / C-Reactive Protein; N9YNS0M02X / Acetylcholine
  • [Other-IDs] NLM/ PMC3145077
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71. |......... 1%  Modla Z, Szabó I: [Possibilities of the therapeutic use of electrophoresis in diseases of the temporomandibular joint]. Fogorv Sz; 1981 Apr;74(4):108-10
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  • [Title] [Possibilities of the therapeutic use of electrophoresis in diseases of the temporomandibular joint].
  • [MeSH-major] Iontophoresis. Lidocaine / therapeutic use. Prednisolone / therapeutic use. Temporomandibular Joint Disorders / drug therapy

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  • (PMID = 6945189.001).
  • [ISSN] 0015-5314
  • [Journal-full-title] Fogorvosi szemle
  • [ISO-abbreviation] Fogorv Sz
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] HUNGARY
  • [Chemical-registry-number] 0 / Muscle Relaxants, Central; 0 / Parasympatholytics; 98PI200987 / Lidocaine; 9PHQ9Y1OLM / Prednisolone
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72. |......... 1%  Sandoo A, Carroll D, Metsios GS, Kitas GD, Veldhuijzen van Zanten JJ: The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther; 2011;13(3):R99
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  • INTRODUCTION: Patients with rheumatoid arthritis (RA) are at an increased risk for cardiovascular disease (CVD).
  • One of the earliest manifestations of CVD is endothelial dysfunction (ED).
  • ED can occur in both the microcirculation and the macrocirculation, and these manifestations might be relatively independent of each other.
  • METHODS: Ninety-nine RA patients (72 females, mean age (± SD) 56 ± 12 years), underwent assessments of endothelial-dependent (acetylcholine) and endothelial-independent (sodium nitroprusside) microvascular vasodilatory function (laser Doppler imaging with iontophoresis), as well as endothelial-dependent (flow-mediated dilation) and endothelial-independent (glyceryl trinitrate-mediated dilation) macrovascular vasodilatory function.
  • CONCLUSIONS: Microvascular and macrovascular endothelial function were independent of each other in patients with RA, suggesting differential regulation of endothelial function in these two vascular beds.
  • [MeSH-minor] Acetylcholine / administration & dosage. Adult. Aged. Cardiovascular Diseases / physiopathology. Cross-Sectional Studies. Female. Humans. Hyperemia / physiopathology. Iontophoresis. Laser-Doppler Flowmetry. Male. Middle Aged. Nitroglycerin / administration & dosage. Nitroprusside / administration & dosage

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  • (PMID = 21693023.001).
  • [ISSN] 1478-6362
  • [Journal-full-title] Arthritis research & therapy
  • [ISO-abbreviation] Arthritis Res. Ther.
  • [Language] eng
  • [Grant] United Kingdom / Arthritis Research UK / /
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Vasodilator Agents; 169D1260KM / Nitroprusside; G59M7S0WS3 / Nitroglycerin; N9YNS0M02X / Acetylcholine
  • [Other-IDs] NLM/ PMC3218914
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73. |......... 1%  Rosenthal M: The application of an extract of human placenta in the treatment of rheumatic affections. Int J Tissue React; 1982;4(2):147-51
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  • [Title] The application of an extract of human placenta in the treatment of rheumatic affections.
  • Iontophoretic application of Placenta-Lucchini in combination with catalase and mucopolysaccharidase for the treatment of acute rheumatic inflammation results in significant clinical improvement.
  • Intra-articular application of Placenta in the arthritis joints of patients with rheumatoid arthritis results in a significant improvement as compared with placebo.
  • Intra-articular application of Placenta prolongs local arthritic remissions induced by steroids.
  • [MeSH-major] Placental Extracts / therapeutic use. Rheumatic Diseases / drug therapy
  • [MeSH-minor] Arthritis, Rheumatoid / drug therapy. Humans. Injections, Intra-Articular. Iontophoresis. Knee Joint / drug effects. Knee Joint / pathology. Tennis Elbow / drug therapy

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  • (PMID = 6981593.001).
  • [ISSN] 0250-0868
  • [Journal-full-title] International journal of tissue reactions
  • [ISO-abbreviation] Int J Tissue React
  • [Language] eng
  • [Publication-type] Clinical Trial; Controlled Clinical Trial; Journal Article
  • [Publication-country] SWITZERLAND
  • [Chemical-registry-number] 0 / Placental Extracts
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74. |......... 1%  Sawyer M, Zbieranek CK: The treatment of soft tissue after spinal injury. Clin Sports Med; 1986 Apr;5(2):387-405
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  • [Title] The treatment of soft tissue after spinal injury.
  • There are a number of modalities available for the treatment of soft tissue that are applicable to spinal injuries.
  • Only through careful evaluation and specific diagnosis can these methods of treatment be utilized to their fullest potential.
  • Direct treatment of the mechanical derangement must take precedence when such conditions exist.
  • The total treatment must incorporate patient education in posture and positioning as well as prophylactic measures.
  • It must always be remembered that treatment of soft tissue alone rarely provides long-lasting relief of symptoms.
  • [MeSH-major] Athletic Injuries / therapy. Back Pain / therapy. Contracture / therapy. Muscles / injuries. Myofascial Pain Syndromes / therapy. Spinal Injuries / therapy
  • [MeSH-minor] Chlorofluorocarbons, Methane / therapeutic use. Cryotherapy. Electric Stimulation Therapy. Hot Temperature / therapeutic use. Humans. Iontophoresis. Massage. Ultrasonic Therapy

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  • (PMID = 2937557.001).
  • [ISSN] 0278-5919
  • [Journal-full-title] Clinics in sports medicine
  • [ISO-abbreviation] Clin Sports Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Chlorofluorocarbons, Methane; 0 / fluori-methane
  • [Number-of-references] 57
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75. |......... 1%  Ivanov VV, Shcherbinina IP, Bogauri IM: [Use of laser irradiation in the complex ambulatory treatment of arthrosoarthritis]. Khirurgiia (Mosk); 1990 Jun;(6):24-6
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  • [Title] [Use of laser irradiation in the complex ambulatory treatment of arthrosoarthritis].
  • The article discusses experience with the treatment of 60 patients with arthrosoarthritis deformans of various large joints by the traditional conservative methods and with the use of laser radiation by an Uzor biomedical laser device.
  • The authors noted a positive effect of laser radiation on the pathological processes developing in the region of the involved joint, which reduced the terms of treatment from 24.4 to 10.4 days and considerably reduced the number of recurrences in the immediate period.
  • [MeSH-major] Arm. Joints / radiation effects. Laser Therapy. Leg. Osteoarthritis / radiotherapy
  • [MeSH-minor] Adult. Ambulatory Care. Combined Modality Therapy. Female. Humans. Hydrocortisone / administration & dosage. Iontophoresis. Male. Middle Aged

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  • (PMID = 2214570.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] WI4X0X7BPJ / Hydrocortisone
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76. |......... 1%  Nitz AJ: Physical therapy management of the shoulder. Phys Ther; 1986 Dec;66(12):1912-9
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  • [Title] Physical therapy management of the shoulder.
  • This article presents an overview of physical therapy management for patients with pathological musculoskeletal conditions of the shoulder.
  • The importance of a thorough physical examination is stressed because proper treatment is based on this information.
  • Medical and surgical treatments for common shoulder disorders also are discussed.
  • [MeSH-major] Physical Therapy Modalities / methods. Shoulder Joint
  • [MeSH-minor] Bursitis / therapy. Cryosurgery. Exercise Therapy. Hot Temperature / therapeutic use. Humans. Immobilization. Iontophoresis. Joint Diseases / therapy. Shoulder Dislocation / therapy. Tendinopathy / therapy. Transcutaneous Electric Nerve Stimulation

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  • (PMID = 3491371.001).
  • [ISSN] 0031-9023
  • [Journal-full-title] Physical therapy
  • [ISO-abbreviation] Phys Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Other-IDs] NASA/ 87067757
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77. |......... 1%  Farrell PM, Koscik RE: Sweat chloride concentrations in infants homozygous or heterozygous for F508 cystic fibrosis. Pediatrics; 1996 Apr;97(4):524-8
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  • METHODOLOGY: Infants were evaluated using pilocarpine iontophoresis and measurement of sweat volume and chloride concentration.
  • Patients with CF who are F508 homozygotes or F508 compound heterozygotes or who have two other non-F508 mutant alleles were shown to have similar sweat chloride levels, with mean values of 99.9, 98.8, and 96.6 mEq/L, respectively.
  • CONCLUSIONS: Quantitative pilocarpine iontophoresis can be used successfully in infants younger than 6 weeks of age who are undergoing routine diagnostic evaluations to follow up newborn screening test results that are positive for CF.
  • [MeSH-minor] Age Factors. Alleles. Base Composition. Codon / genetics. DNA / analysis. Follow-Up Studies. Gene Deletion. Genes, Regulator / genetics. Genotype. Heterozygote. Homozygote. Humans. Infant. Infant, Newborn. Iontophoresis. Mutation / genetics. Neonatal Screening. Parasympathomimetics / diagnostic use. Pilocarpine / diagnostic use. Trypsinogen / analysis

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  • (PMID = 8632940.001).
  • [ISSN] 0031-4005
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK 34108; United States / NCRR NIH HHS / RR / RR 03186
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Chlorides; 0 / Codon; 0 / Parasympathomimetics; 01MI4Q9DI3 / Pilocarpine; 9002-08-8 / Trypsinogen; 9007-49-2 / DNA
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78. |......... 1%  Coccia G, Mazzoni C: [Iontophoretic administration of antiphlogistic drugs in orthopedics and traumatology (butazolidine)]. Minerva Ortop; 1969 Sep;20(9):429-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Back Pain / drug therapy. Iontophoresis. Joint Diseases / drug therapy. Phenylbutazone / administration & dosage
  • [MeSH-minor] Adult. Aged. Brachial Plexus Neuritis / drug therapy. Humans. Intervertebral Disc Displacement / drug therapy. Middle Aged. Orthopedics. Periarthritis / drug therapy. Sciatica / drug therapy. Tenosynovitis / drug therapy

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  • (PMID = 4249941.001).
  • [ISSN] 0026-4911
  • [Journal-full-title] Minerva ortopedica
  • [ISO-abbreviation] Minerva Ortop
  • [Language] ita
  • [Publication-type] Journal Article
  • [Publication-country] ITALY
  • [Chemical-registry-number] GN5P7K3T8S / Phenylbutazone
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79. |......... 1%  CAMBRA MERCADER J: [Personal experience with iontophoresis]. Rev Esp Reum Enferm Osteoartic; 1952 Jan;4(4):234-40
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  • [Title] [Personal experience with iontophoresis].
  • [Transliterated title] Nuestra experiencia en el uso de la iontoforesis.
  • [MeSH-major] Arthritis, Rheumatoid / therapy. Ion Exchange

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  • (PMID = 12994228.001).
  • [ISSN] 0048-7791
  • [Journal-full-title] Revista española de reumatismo y enfermedades osteoarticulares
  • [ISO-abbreviation] Rev Esp Reum Enferm Osteoartic
  • [Language] und
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Other-IDs] CLML/ 5323:18545:53:282
  • [Keywords] NLM ; ARTHRITIS, RHEUMATOID/therapy (major topic) / ION TRANSFER (major topic)
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80. |......... 1%  Chmielewski F: [Treatment of degenerative joint diseases with hydrocortisone electrophoresis]. Wiad Lek; 1971 Jul 1;24(13):1237-9
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  • [Title] [Treatment of degenerative joint diseases with hydrocortisone electrophoresis].
  • [MeSH-major] Hydrocortisone / administration & dosage. Osteoarthritis / drug therapy
  • [MeSH-minor] Adult. Aged. Female. Humans. Iontophoresis. Male. Methods. Middle Aged

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  • (PMID = 5094448.001).
  • [ISSN] 0043-5147
  • [Journal-full-title] Wiadomości lekarskie (Warsaw, Poland : 1960)
  • [ISO-abbreviation] Wiad. Lek.
  • [Language] pol
  • [Publication-type] Journal Article
  • [Publication-country] POLAND
  • [Chemical-registry-number] WI4X0X7BPJ / Hydrocortisone
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81. |......... 1%  Brown FF, Robinson ME, Riley JL 3rd, Gremillion HA, McSolay J, Meyers G: Better palpation of pain: reliability and validity of a new pressure pain protocol in TMD. Cranio; 2000 Jan;18(1):58-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Better palpation of pain: reliability and validity of a new pressure pain protocol in TMD.
  • The purpose of this research was to employ a double-blind placebo control design of iontophoretically administered lidocaine to assess the test-retest reliability and validity of a magnitude matching procedure using a pressure algometer.
  • In studies in the literature on assessment of pain in temporomandibular disorders (TMD), the pressure algometer has been found to be a reliable means of measuring pressure-pain threshold and a sensitive measure of treatment-response in the laboratory.
  • The validity study used iontophoresis as an anesthetic in a double-blind placebo and no-treatment control design.
  • However, differences in response bias were found, with both the placebo control and no-treatment control groups differing from the experimental group but not from each other.
  • [MeSH-minor] Adult. Analysis of Variance. Anesthetics, Local / administration & dosage. Double-Blind Method. Facial Pain / etiology. Female. Humans. Iontophoresis. Lidocaine / administration & dosage. Male. Masseter Muscle / physiopathology. Pain Threshold. Pressure. Reproducibility of Results. Sensitivity and Specificity. Statistics, Nonparametric. Temporomandibular Joint Disorders / complications. Temporomandibular Joint Disorders / diagnosis

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  • (PMID = 11202817.001).
  • [ISSN] 0886-9634
  • [Journal-full-title] Cranio : the journal of craniomandibular practice
  • [ISO-abbreviation] Cranio
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / 1P20DE12396-01; United States / NIDCR NIH HHS / DE / DE-07283
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Validation Studies
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, Local; 98PI200987 / Lidocaine
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82. |......... 1%  BOYKIKEVA S, YONKOV S, STOYKOV S, OVAGUIMOV O: [THERAPEUTIC EFFECTS IN THE TREATMENT OF BECHTEREW'S DISEASE USING GLUTAMIC ACID ELECTROPHORESIS]. Folia Med (Plovdiv); 1964;6:320-8
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  • [Title] [THERAPEUTIC EFFECTS IN THE TREATMENT OF BECHTEREW'S DISEASE USING GLUTAMIC ACID ELECTROPHORESIS].
  • [Transliterated title] EFFETS THERAPEUTIQUES DANS LE TRAITEMENT DE LA MALADIE DE BECHTEREV PAR ELECTROPHORESE A L'ACIDE GLUTAMIQUE.
  • [MeSH-major] Glutamates. Iontophoresis. Spondylitis, Ankylosing

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  • (PMID = 14282258.001).
  • [ISSN] 0204-8043
  • [Journal-full-title] Folia medica
  • [ISO-abbreviation] Folia Med (Plovdiv)
  • [Language] fre
  • [Publication-type] Journal Article
  • [Publication-country] BULGARIA
  • [Chemical-registry-number] 0 / Glutamates
  • [Keywords] NLM ; GLUTAMATES (major topic) / IONTOPHORESIS (major topic) / SPONDYLITIS, ANKYLOSING (major topic)
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83. |......... 1%  KACER V, ZABRODSKY J, KALISTA V, KEBORT J: [ELECTROPHORETIC TREATMENT OF POST-TRAUMATIC AND DEGENERATIVE ANKYLOSES IN AGED SUBJECTS]. Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove; 1963;72:253-7
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  • [Title] [ELECTROPHORETIC TREATMENT OF POST-TRAUMATIC AND DEGENERATIVE ANKYLOSES IN AGED SUBJECTS].
  • [MeSH-major] Ankylosis. Chlorides. Geriatrics. Iontophoresis. Potassium. Wounds and Injuries

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  • HSDB. structure - POTASSIUM.
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  • (PMID = 14100456.001).
  • [ISSN] 0049-5514
  • [Journal-full-title] Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové
  • [ISO-abbreviation] Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove
  • [Language] cze
  • [Publication-type] Journal Article
  • [Publication-country] CZECH REPUBLIC
  • [Chemical-registry-number] 0 / Chlorides; RWP5GA015D / Potassium
  • [Keywords] NLM ; ANKYLOSIS (major topic) / CHLORIDES (major topic) / GERIATRICS (major topic) / IONTOPHORESIS (major topic) / POTASSIUM (major topic) / WOUNDS AND INJURIES (major topic)
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84. |......... 1%  Cameron MH: Fighting inflammation. Rehab Manag; 2005 Jul;18(6):26-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Dexamethasone / therapeutic use. Inflammation / drug therapy. Iontophoresis / methods. Joint Diseases / drug therapy
  • [MeSH-minor] Adult. Biological Availability. Female. Humans. Male. Middle Aged. Pain Measurement / drug effects. Patient Satisfaction. Prognosis. Risk Assessment. Treatment Outcome

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  • (PMID = 16021948.001).
  • [ISSN] 0899-6237
  • [Journal-full-title] Rehab management
  • [ISO-abbreviation] Rehab Manag
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 7S5I7G3JQL / Dexamethasone
  • [Number-of-references] 8
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85. |......... 1%  Klein W, Schellnack K: [Electrodiagnosis and electrotherapy in orthopedic practice. 2. Electrotherapy in the treatment of orthopedic diseases]. Beitr Orthop Traumatol; 1972 Aug;19(8):433-8
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  • [Title] [Electrodiagnosis and electrotherapy in orthopedic practice. 2. Electrotherapy in the treatment of orthopedic diseases].
  • [MeSH-major] Bone Diseases / therapy. Electric Stimulation Therapy
  • [MeSH-minor] Humans. Iontophoresis. Joint Diseases / therapy

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  • (PMID = 4541288.001).
  • [ISSN] 0005-8149
  • [Journal-full-title] Beiträge zur Orthopädie und Traumatologie
  • [ISO-abbreviation] Beitr Orthop Traumatol
  • [Language] ger
  • [Publication-type] Journal Article
  • [Publication-country] GERMANY, EAST
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86. |......... 1%  Carlson AH: Patch work. Rehab Manag; 2009 Jan-Feb;22(1):36-8, 41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Joint Diseases / therapy. Muscular Diseases / therapy
  • [MeSH-minor] Humans. Inflammation / therapy. Iontophoresis / economics. Iontophoresis / methods

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  • (PMID = 19323102.001).
  • [ISSN] 0899-6237
  • [Journal-full-title] Rehab management
  • [ISO-abbreviation] Rehab Manag
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. |......... 1%  Thomas T, Beaudreuil J: [Non-traumatic pathology of the shoulder: medical treatment]. Rev Prat; 2006 Sep 30;56(14):1550-5
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  • [Title] [Non-traumatic pathology of the shoulder: medical treatment].
  • [Transliterated title] Pathologie non traumatique de l'épaule: les traitements médicaux.
  • Recently published meta-analyses emphasized weak methodology of clinical research evaluating medical treatment of non-traumatic shoulder pathology.
  • Experts recommend medical treatment as the first step in the management of rotator cuff tendinopathies, the focus of this review.
  • This step precedes surgical treatment of rotator cuff tear with the objective of recovering passive motion of the shoulder.
  • Therefore, the physician prior treatment has to establish a lesion diagnostic, which is necessary to propose an appropriate strategy.
  • Medical treatment includes NSAID, local injections of corticosteroids and physiotherapy with the double objective of a painless shoulder and normal range of motion.
  • In case rotator cuff calcifying tendinitis, medical treatment is specific with first NSAID and local injections of cortico-steroïds, second needle aspiration and third arthroscopic removal, which remains the gold-standard procedure when other treatments failed.
  • [MeSH-major] Arthritis / drug therapy. Rotator Cuff. Shoulder Joint. Shoulder Pain / drug therapy. Tendinopathy / drug therapy
  • [MeSH-minor] Adrenal Cortex Hormones / administration & dosage. Adrenal Cortex Hormones / therapeutic use. Aged. Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Arthroscopy. Calcinosis / therapy. Exercise Therapy. Female. Humans. Injections. Iontophoresis. Male. Meta-Analysis as Topic. Physical Therapy Modalities. Prognosis. Prospective Studies. Range of Motion, Articular. Research. Rupture. Treatment Outcome

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  • (PMID = 17139866.001).
  • [ISSN] 0035-2640
  • [Journal-full-title] La Revue du praticien
  • [ISO-abbreviation] Rev Prat
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Anti-Inflammatory Agents, Non-Steroidal
  • [Number-of-references] 10
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88. |......... 1%  Neugebauer V, Weiretter F, Schaible HG: Involvement of substance P and neurokinin-1 receptors in the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint. J Neurophysiol; 1995 Apr;73(4):1574-83
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  • [Title] Involvement of substance P and neurokinin-1 receptors in the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint.
  • In all experiments one nociceptive neuron with knee input was identified, and the responses to mechanical stimuli and the receptive fields were monitored before and after induction of inflammation by the injections of kaolin and carrageenan into the knee joint.
  • 2. After the injections of kaolin and carrageenan into the knee joint, untreated control neurons (n = 8) developed hyperexcitability consisting of enhanced responses to noxious stimuli applied to the injected knee and the noninjected ankle, of an enhancement or induction of the responses to innocuous pressure applied to the joints and of an expansion of the receptive field.
  • 3. After development of inflammation and hyperexcitability, both the responses to innocuous and noxious pressure applied to the inflamed knee joint were reduced by the ionophoretic (n = 16 neurons) and intravenous administration (n = 9 neurons) of CP96,345 (tested 4.5-8 h postkaolin).
  • Similarly, the responses to innocuous and noxious pressure applied to the noninflamed ankle were reduced by CP96,345 after inflammation had developed in the knee joint.(ABSTRACT TRUNCATED AT 400 WORDS)
  • [MeSH-minor] Animals. Biphenyl Compounds / pharmacology. Electrophysiology. Hindlimb / physiopathology. Hypnotics and Sedatives / pharmacology. Iontophoresis. Joints / physiopathology. Male. Neurokinin-1 Receptor Antagonists. Nociceptors / drug effects. Nociceptors / physiology. Physical Stimulation. Rats. Rats, Wistar

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  • (PMID = 7643168.001).
  • [ISSN] 0022-3077
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Biphenyl Compounds; 0 / Hypnotics and Sedatives; 0 / Neurokinin-1 Receptor Antagonists; 0 / Receptors, Neurokinin-1; 132746-60-2 / CP 96345
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89. |......... 1%  Neugebauer V, Lücke T, Schaible HG: N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint. J Neurophysiol; 1993 Oct;70(4):1365-77
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  • [Title] N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint.
  • 1. In 22 anesthetized rats we studied the involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the generation and maintenance of hyperexcitability in spinal cord neurons with knee input that develops in the course of an acute inflammation in the knee.
  • In all experiments one neuron with knee input was identified, and the responses to mechanical stimuli and the receptive fields were monitored before and after induction of inflammation by the intra-articular injections of kaolin and carrageenan into the joint cavity.
  • In most experiments multibarrel electrodes were used to administer specific NMDA and non-NMDA antagonists ionophoretically close to the neuron to test their effects on the inflammation-evoked changes.
  • During this treatment none of the four neurons exhibited the changes of responsiveness that were usually seen in control animals, although swelling of the knee developed in the same fashion as in control rats.
  • The doses of ketamine and AP5 were sufficient to reduce the responses to NMDA, whereas the responses to the non-NMDA agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) were not influenced.
  • 4. The ionophoretic application of the non-NMDA antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) during the injections of the kaolin and carrageenan and up to 103 min postkaolin also prevented the generation of hyperexcitability in six neurons in six rats.(ABSTRACT TRUNCATED AT 400 WORDS)
  • [MeSH-major] Arthritis, Experimental / drug therapy. Neurons / drug effects. Receptors, Amino Acid / antagonists & inhibitors. Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors. Spinal Cord / cytology
  • [MeSH-minor] 2-Amino-5-phosphonovalerate / pharmacology. 6-Cyano-7-nitroquinoxaline-2,3-dione. Animals. Electrophysiology. Hindlimb / pathology. Injections, Intravenous. Iontophoresis. Ketamine / administration & dosage. Ketamine / pharmacology. Male. Physical Stimulation. Quinoxalines / pharmacology. Rats. Rats, Wistar

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  • (PMID = 7904298.001).
  • [ISSN] 0022-3077
  • [Journal-full-title] Journal of neurophysiology
  • [ISO-abbreviation] J. Neurophysiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Quinoxalines; 0 / Receptors, Amino Acid; 0 / Receptors, N-Methyl-D-Aspartate; 690G0D6V8H / Ketamine; 6OTE87SCCW / 6-Cyano-7-nitroquinoxaline-2,3-dione; 76726-92-6 / 2-Amino-5-phosphonovalerate
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90. |......... 1%  BOGOMOLOVA FA: [The effect of novocain electrophoresis on the state of the peripheral blood in children with rheumatism]. Azerbaidzhanskii Meditsinskii Zhurnal; 1961 Dec;12:23-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Child. Infant. Iontophoresis. Procaine / therapy. Rheumatic Fever

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  • HSDB. structure - PROCAINE.
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  • (PMID = 13870605.001).
  • [ISSN] 0005-2523
  • [Journal-full-title] Azerbaĭdzhanskiĭ medit͡sinskiĭ zhurnal = Aserbaidschanische medizinische Zeitschrift
  • [ISO-abbreviation] Azerbaidzhanskii Meditsinskii Zhurnal
  • [Language] rus
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Chemical-registry-number] 4Z8Y51M438 / Procaine
  • [Keywords] NLM ; IONTOPHORESIS (major topic) / PROCAINE/therapy (major topic) / RHEUMATIC FEVER/in infancy and childhood (major topic)
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91. |......... 1%  BOFFANO M: [TRANSCUTANEOUS TRANSPORT OF SUBSTANCE BY ELECTROLYTES]. Minerva Radiol Fisioter Radiobiol; 1964 Dec;30:575-80
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  • [MeSH-major] Iontophoresis. Joint Diseases. Neuralgia. Salicylates

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  • (PMID = 14267944.001).
  • [ISSN] 0544-2656
  • [Journal-full-title] Minerva radiologica, fisioterapica e radiobiologica
  • [ISO-abbreviation] Minerva Radiol Fisioter Radiobiol
  • [Language] ita
  • [Publication-type] Journal Article
  • [Publication-country] ITALY
  • [Chemical-registry-number] 0 / Salicylates
  • [Keywords] NLM ; IONTOPHORESIS (major topic) / JOINT DISEASES (major topic) / NEURALGIA (major topic) / SALICYLATES (major topic)
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92. |......... 1%  MAGISTRO CM: HYALURONIDASE BY IOTOPHORESIS IN THE TREATMENT OF EDEMA. Phys Ther; 1964 Mar;44:169-75
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  • [Title] HYALURONIDASE BY IOTOPHORESIS IN THE TREATMENT OF EDEMA.
  • [MeSH-major] Ankle. Bursitis. Edema. Fractures, Bone. Hematoma. Hyaluronoglucosaminidase. Iontophoresis. Joint Diseases. Lymphedema. Sprains and Strains. Thrombophlebitis. Wrist Injuries

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  • (PMID = 14130077.001).
  • [ISSN] 0031-9023
  • [Journal-full-title] Physical therapy
  • [ISO-abbreviation] Phys Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] EC 3.2.1.35 / Hyaluronoglucosaminidase
  • [Keywords] NLM ; ANKLE (major topic) / BURSITIS (major topic) / EDEMA (major topic) / FRACTURES (major topic) / HEMATOMA (major topic) / HYALURONIDASE (major topic) / IONTOPHORESIS (major topic) / JOINT DISEASES (major topic) / LYMPHEDEMA (major topic) / SPRAINS AND STRAINS (major topic) / THROMBOPHLEBITIS (major topic) / WRIST INJURIES (major topic)
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93. |......... 1%  Uzhumetskene II: [Use of ultrasonics in the overall treatment of temporomandibular joint diseases]. Stomatologiia (Mosk); 1980 Nov-Dec;59(6):48-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Use of ultrasonics in the overall treatment of temporomandibular joint diseases].
  • [MeSH-major] Temporomandibular Joint Dysfunction Syndrome / therapy. Ultrasonic Therapy / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Evaluation Studies as Topic. Humans. Iontophoresis / methods. Middle Aged. Ointments. Potassium Iodide / administration & dosage

  • HSDB. structure - POTASSIUM IODIDE.
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  • (PMID = 6935813.001).
  • [ISSN] 0039-1735
  • [Journal-full-title] Stomatologii͡a
  • [ISO-abbreviation] Stomatologiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] USSR
  • [Chemical-registry-number] 0 / Ointments; 1C4QK22F9J / Potassium Iodide
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94. |......... 1%  Kanazirska Z, Raynova I: [Treatment of rheumatoid arthritis of the temporomandibular joint by electrophoresis with Pomorie lye]. Stomatologiia (Sofiia); 1987 Mar-Apr;69(2):26-8
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  • [Title] [Treatment of rheumatoid arthritis of the temporomandibular joint by electrophoresis with Pomorie lye].
  • [MeSH-major] Arthritis, Rheumatoid / drug therapy. Caustics / therapeutic use. Lye / therapeutic use. Temporomandibular Joint Disorders / drug therapy
  • [MeSH-minor] Humans. Iontophoresis


95. |......... 1%  Famaey JP, Broux G, Cleppe D, Deroulez A, Duckerts F, Evrard F, Goethals L, Vanhecke J, Verbruggen L, Tyberghein JM: Ionisation with Voltaren. A multi-centre trial. J Belge Med Phys Rehabil; 1982;5(2):55-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Anti-Inflammatory Agents / administration & dosage. Diclofenac / administration & dosage. Iontophoresis. Joint Diseases / therapy. Muscular Diseases / therapy. Phenylacetates / administration & dosage

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  • HSDB. structure - DICLOFENAC.
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  • (PMID = 7153205.001).
  • [ISSN] 0250-4766
  • [Journal-full-title] Journal belge de médecine physique et de réhabilitation. = Belgisch tijdschrift voor fysische geneeskunde en rehabilitatie
  • [ISO-abbreviation] J Belge Med Phys Rehabil
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] BELGIUM
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Phenylacetates; 144O8QL0L1 / Diclofenac
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96. |......... 1%  BEUTL O, CLEMENTSCHITSCH A: [Iontophoresis in therapy of humeroscapular periarthritis and epicondylitis of the humerus]. Wien Med Wochenschr; 1952 Jan 12;102(2):36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Iontophoresis in therapy of humeroscapular periarthritis and epicondylitis of the humerus].
  • [MeSH-major] Disease. Humerus. Ion Exchange / therapeutic use. Periarthritis / therapy

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  • (PMID = 14913955.001).
  • [ISSN] 0043-5341
  • [Journal-full-title] Wiener medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Wien Med Wochenschr
  • [Language] und
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Other-IDs] CLML/ 5221:44558:178:195:284
  • [Keywords] NLM ; HUMERUS/diseases (major topic) / ION TRANSFER/therapeutic use (major topic) / PERIARTHRITIS/therapy (major topic)
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97. |......... 1%  Sharif Naeini R, Cahill CM, Ribeiro-da-Silva A, Ménard HA, Henry JL: Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. Eur J Neurosci; 2005 Oct;22(8):2005-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Moreover, neuronal responses elicited by an innocuous stimulation with von Frey filaments applied to the arthritic joint were greater in amplitude and produced the afterdischarge that normally characterizes a nociceptive response.
  • In contrast to the response in control animals, passive movement of the arthritic joint produced an increase in the amplitude of the response of these neurons to iontophoretic application of glutamate receptor agonists over a time frame of 10-30 min.
  • Ultrastructural analysis of the dorsal horn revealed that movement of the arthritic joint also induced NK-1 receptor internalization, indicative of nociception.
  • Thus, although treatment of arthritis should obviously target its peripheral aetiology, targeting its central components is a logical therapeutic complementary objective.
  • [MeSH-minor] Action Potentials / drug effects. Action Potentials / physiology. Action Potentials / radiation effects. Animals. Ankle / pathology. Disease Models, Animal. Dose-Response Relationship, Drug. Dose-Response Relationship, Radiation. Electric Stimulation / methods. Excitatory Amino Acid Agonists / pharmacology. Freund's Adjuvant. Functional Laterality. Immunohistochemistry / methods. Iontophoresis / methods. Male. Microscopy, Immunoelectron. N-Methylaspartate / pharmacology. Pain Measurement / methods. Pain Threshold / physiology. Rats. Rats, Sprague-Dawley. Receptors, Neurokinin-1 / metabolism. Substance P / metabolism. Time Factors. alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid / pharmacology

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  • (PMID = 16262639.001).
  • [ISSN] 0953-816X
  • [Journal-full-title] The European journal of neuroscience
  • [ISO-abbreviation] Eur. J. Neurosci.
  • [Language] eng
  • [Grant] Canada / Canadian Institutes of Health Research / / 13460
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Excitatory Amino Acid Agonists; 0 / Receptors, Neurokinin-1; 33507-63-0 / Substance P; 6384-92-5 / N-Methylaspartate; 77521-29-0 / alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; 9007-81-2 / Freund's Adjuvant
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98. |......... 1%  COYER AB: Citrate iontophoresis in rheumatoid arthritis of the hands. Ann Phys Med; 1954 Jan;2(1):16-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Citrate iontophoresis in rheumatoid arthritis of the hands.
  • [MeSH-major] Arthritis, Rheumatoid / therapy. Citrates / therapeutic use. Disease. Electrophoresis. Hand

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  • (PMID = 13149048.001).
  • [ISSN] 0365-5547
  • [Journal-full-title] Annals of physical medicine
  • [ISO-abbreviation] Ann Phys Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Chemical-registry-number] 0 / Citrates
  • [Other-IDs] CLML/ 5426:11587:45:111:151:197
  • [Keywords] NLM ; ARTHRITIS, RHEUMATOID/therapy (major topic) / CITRATES/therapeutic use (major topic) / ELECTROPHORESIS (major topic) / HAND/diseases (major topic)
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99. |......... 1%  Neugebauer V, Rumenapp P, Schaible HG: The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat. Eur J Neurosci; 1996 Feb;8(2):249-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat.
  • In spinal cord neurons in anesthetized rats, the role on neurokinin A and neurokinin-2 receptors in the processing of nociceptive information from the knee joint was studied.
  • The specific non-peptide antagonist at the neurokinin-2 receptor, SR48968, its inactive R-enantiomer, SR48965, neurokinin A, substance P and (RS)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), were administered ionophoretically close to neurons with input from the knee joint.
  • In most neurons with input from the normal knee joint, SR48968 reduced dose-dependently the responses to noxious pressure with applied to the knee, and in approximately 50% of the neurons the responses to innocuous pressure.
  • The administration of SR48968 during the induction of an experimental joint inflammation markedly attenuated the development of inflammation-evoked hyperexcitability.
  • In hyperexcitable neurons with input from the inflamed joint, SR48968 reduced the responses to noxious and innocuous pressure.
  • The relative reduction of the responses was more pronounced than in neurons with input from the normal joint.
  • These data show that neurokinin-2 receptors are involved in the spinal processing of nociceptive information from the normal joint.
  • In summary, spinal neurokinin-2 receptors are important in the generation of pain in the normal and inflamed joint.
  • [MeSH-major] Knee Joint / physiopathology. Nociceptors / physiology. Pain / physiopathology. Receptors, Neurokinin-2 / physiology. Spinal Cord / physiopathology
  • [MeSH-minor] Animals. Arthritis / chemically induced. Arthritis / complications. Arthritis / physiopathology. Benzamides / pharmacology. Carrageenan / toxicity. Hyperalgesia / etiology. Hyperalgesia / physiopathology. Iontophoresis. Kaolin / toxicity. Male. Neurokinin A / pharmacology. Piperidines / pharmacology. Pressure / adverse effects. Rats. Rats, Wistar. Substance P / pharmacology. alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid / pharmacology

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  • (PMID = 8714696.001).
  • [ISSN] 0953-816X
  • [Journal-full-title] The European journal of neuroscience
  • [ISO-abbreviation] Eur. J. Neurosci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Benzamides; 0 / Piperidines; 0 / Receptors, Neurokinin-2; 142001-63-6 / SR 48968; 24H4NWX5CO / Kaolin; 33507-63-0 / Substance P; 77521-29-0 / alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; 86933-74-6 / Neurokinin A; 9000-07-1 / Carrageenan
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100. |......... 1%  Gostkowski K, Aleksandrowicz J: [Therapeutic use of positive ion current by the method of Prof. Gostkowski. Preliminary report]. Przegl Lek; 1969;25(7):541-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Iontophoresis. Neuralgia / therapy. Spondylitis, Ankylosing / therapy. Thrombophlebitis / therapy

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  • (PMID = 5343597.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] Journal Article
  • [Publication-country] POLAND
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