[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 289
1. Willermet CM, Edgar HJ: Dental morphology and ancestry in Albuquerque, New Mexico Hispanics. Homo; 2009;60(3):207-24
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The term "Hispanic" groups people from Central and South America and the Caribbean, combining disparate cultures, languages, and ancestry, and masking biological differences.
  • Historical and current admixture patterns within these populations and with indigenous and European-, African-, and/or Asian- derived populations complicate the biological picture.
  • Although "Hispanic" has little biological meaning, it is used widely in epidemiology, disease management, and forensics as a biologically significant group.
  • An interdisciplinary approach combining historical, cultural, and biological data can characterize regional and temporal differences between Hispanic populations.
  • We examined biological distances with a population of central New Mexico Hispanics, as a case study of the local specificity of population history.
  • We collected dental morphological trait frequencies from samples of recent Albuquerque-area Hispanic Americans and several ancestral and contemporary groups.
  • Our results indicate that Albuquerque Hispanics are more similar to their European and African ancestral groups than to Native Americans in New Mexico.
  • Additionally, their affinity to Native Americans is greater with prehistoric rather than contemporary samples.
  • We argue that these results reflect a local rather than pan-Hispanic admixture pattern; they underscore that populations are better understood at the local and regional levels.
  • It is undesirable to make sweeping biological generalizations for groups known to be geographically and genetically disparate.
  • This research is part of a growing trend in biological research concerning Hispanics and other groups-an emphasis on local samples, informed by historical, cultural, and biological factors.
  • [MeSH-major] American Native Continental Ancestry Group. Hispanic Americans. Paleodontology. Tooth
  • [MeSH-minor] African Americans. African Continental Ancestry Group. European Continental Ancestry Group. History, 15th Century. History, 16th Century. History, 17th Century. History, 18th Century. History, 19th Century. History, 20th Century. History, Medieval. Humans. Indians, North American. New Mexico

  • MedlinePlus Health Information. consumer health - Hispanic American Health.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19394926.001).
  • [ISSN] 1618-1301
  • [Journal-full-title] Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen
  • [ISO-abbreviation] Homo
  • [Language] eng
  • [Publication-type] Comparative Study; Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Germany
  •  go-up   go-down


2. Norris CF, Surrey S, Bunin GR, Schwartz E, Buchanan GR, McKenzie SE: Relationship between Fc receptor IIA polymorphism and infection in children with sickle cell disease. J Pediatr; 1996 Jun;128(6):813-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The His(H)-Arg(R) polymorphism at amino acid 131 of the Fc gamma RIIA receptor alters binding affinity for human IgG2 and influences infection with encapsulated organisms in children without sickle cell disease.
  • We hypothesized that the genotype for high-affinity human IgG2 binding (H/H131) is underrepresented in children with sickle cell disease who had encapsulated organism infection.
  • In the 51 individuals with a history of Streptococcus pneumoniae infection, the genotype distribution was not statistically significantly different from that of the control population.
  • CONCLUSIONS: The H/H131 Fc gamma RIIA genotype is overrepresented in black children with sickle cell disease and a history of H. influenzae type b infection but not in those with S. pneumoniae infection.
  • [MeSH-major] African Continental Ancestry Group / genetics. Anemia, Sickle Cell / genetics. Antigens, CD / genetics. Haemophilus Infections / genetics. Opportunistic Infections / genetics. Pneumococcal Infections / genetics. Polymorphism, Genetic / genetics. Receptors, IgG / genetics

  • Genetic Alliance. consumer health - Sickle Cell Disease.
  • MedlinePlus Health Information. consumer health - Haemophilus Infections.
  • MedlinePlus Health Information. consumer health - Pneumococcal Infections.
  • MedlinePlus Health Information. consumer health - Sickle Cell Anemia.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 8648541.001).
  • [ISSN] 0022-3476
  • [Journal-full-title] The Journal of pediatrics
  • [ISO-abbreviation] J. Pediatr.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P30 HD-28815; United States / NIDDK NIH HHS / DK / R01 DK-16691; United States / NHLBI NIH HHS / HL / T32 HL-07150
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Fc gamma receptor IIA; 0 / Receptors, IgG
  •  go-up   go-down


3. Pandey GS, Yanover C, Howard TE, Sauna ZE: Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia a: a computational assessment. PLoS Comput Biol; 2013;9(5):e1003066
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Common non-synonymous single nucleotide polymorphisms (ns-SNPs) in the F8 gene occur as six haplotypes in the human population (denoted H1 to H6) of which H3 and H4 have been associated with an increased risk of developing anti-drug antibodies.
  • We measured the binding and half-life of peptide-MHC-II complexes using synthetic peptides from regions of the Factor VIII protein where ns-SNPs occur and showed that these wild type peptides form stable complexes with six common MHC-II alleles, representing 46.5% of the North American population.
  • Next, we compared the affinities computed by NetMHCIIpan, a neural network-based algorithm for MHC-II peptide binding prediction, to the experimentally measured values and concluded that these are in good agreement (area under the ROC-curve of 0.778 to 0.972 for the six MHC-II variants).
  • Using a computational binding predictor, we were able to expand our analysis to (a) include all wild type peptides spanning each polymorphic position; and (b) consider more MHC-II variants, thus allowing for a better estimation of the risk for clinical manifestation of anti-drug antibodies in the entire population (or a specific sub-population).

  • Genetic Alliance. consumer health - Factor II Deficiency.
  • Genetic Alliance. consumer health - Hemophilia.
  • Immune Epitope Database and Analysis Resource. gene/protein/disease-specific - Related Immune Epitope Information .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Blood. 2000 Feb 15;95(4):1324-9 [10666206.001]
  • [Cites] Blood. 2012 Apr 26;119(17):4073-82 [22394599.001]
  • [Cites] Bioinformatics. 2001 Oct;17(10):942-8 [11673239.001]
  • [Cites] Bioinformatics. 2001 Dec;17(12):1236-7 [11751237.001]
  • [Cites] Eur J Immunol. 2002 Mar;32(3):662-70 [11857340.001]
  • [Cites] Blood. 2003 Feb 15;101(4):1351-8 [12393451.001]
  • [Cites] Nature. 1992 May 21;357(6375):249-52 [1375347.001]
  • [Cites] Am J Hematol. 1993 Apr;42(4):375-9 [8493988.001]
  • [Cites] Cell. 1993 Sep 10;74(5):929-37 [8104103.001]
  • [Cites] Thromb Haemost. 1995 Aug;74(2):619-21 [8584995.001]
  • [Cites] Annu Rev Immunol. 1997;15:297-322 [9143690.001]
  • [Cites] Blood. 1997 Jun 15;89(12):4371-7 [9192760.001]
  • [Cites] Blood. 1999 Apr 1;93(7):2267-73 [10090936.001]
  • [Cites] Thromb Haemost. 1999 Jul;82(1):40-5 [10456452.001]
  • [Cites] Immunity. 2005 Jul;23(1):29-40 [16039577.001]
  • [Cites] Eur J Immunol. 2007 Apr;37(4):946-53 [17357107.001]
  • [Cites] Blood. 2007 May 1;109(9):3713-24 [17209060.001]
  • [Cites] PLoS Comput Biol. 2008 Apr;4(4):e1000048 [18389056.001]
  • [Cites] Haemophilia. 2008 Jul;14 Suppl 3:36-42 [18510520.001]
  • [Cites] PLoS Comput Biol. 2008;4(7):e1000107 [18604266.001]
  • [Cites] Blood. 2008 Jul 15;112(2):240-9 [18469198.001]
  • [Cites] N Engl J Med. 2009 Apr 16;360(16):1618-27 [19369668.001]
  • [Cites] Clin Rev Allergy Immunol. 2009 Oct;37(2):114-24 [19199081.001]
  • [Cites] J Immunol. 2010 Jan 15;184(2):573-81 [20007533.001]
  • [Cites] Immunology. 2010 Jul;130(3):319-28 [20408898.001]
  • [Cites] Curr Opin Hematol. 2010 Sep;17(5):393-7 [20613509.001]
  • [Cites] J Thromb Haemost. 2011 Apr;9(4):689-99 [21251204.001]
  • [Cites] Blood. 2012 Mar 22;119(12):2922-34 [22282501.001]
  • [Cites] N Engl J Med. 2001 Jun 7;344(23):1773-9 [11396445.001]
  • (PMID = 23696725.001).
  • [ISSN] 1553-7358
  • [Journal-full-title] PLoS computational biology
  • [ISO-abbreviation] PLoS Comput. Biol.
  • [Language] ENG
  • [Grant] United States / NHLBI NIH HHS / HL / 1RC2-HL101851; United States / NHLBI NIH HHS / HL / HL-71130; United States / NHLBI NIH HHS / HL / HL-72533
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies; 0 / Histocompatibility Antigens Class II; 0 / Peptide Fragments; 9001-27-8 / Factor VIII
  • [Other-IDs] NLM/ PMC3656107
  •  go-up   go-down


Advertisement
4. Manosuthi W, Butler DM, Pérez-Santiago J, Poon AF, Pillai SK, Mehta SR, Pacold ME, Richman DD, Pond SK, Smith DM: Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure. AIDS; 2010 Jan 28;24(3):411-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We investigated the effect of protease resistance-associated mutations (PRAMs) and population-based HLA haplotype frequencies on polymorphisms found in CRF01_AE pro.
  • HLA binding affinities were estimated using the Immune Epitope Database and Analysis.
  • Of the predominant HLA haplotypes in the Asian regions of CRF01_AE origin, 80% were positively associated with the observed polymorphisms, and estimated HLA binding affinity was estimated to decrease 19-40 fold with the observed polymorphisms at positions 35, 36 and 41.
  • CONCLUSION: Polymorphisms in CRF01_AE protease gene were common, and polymorphisms at residues 10, 20 and 62 most likely represent selection by use of protease inhibitors, whereas R41K and H69K were more likely attributable to recognition of epitopes by the HLA haplotypes of the host population.

  • Genetic Alliance. consumer health - HIV.
  • MedlinePlus Health Information. consumer health - HIV/AIDS.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Top HIV Med. 2008 Apr-May;16(1):62-8 [18441382.001]
  • [Cites] Bioinformatics. 2005 Mar 1;21(5):676-9 [15509596.001]
  • [Cites] Clin Infect Dis. 2008 Jul 15;47(2):266-85 [18549313.001]
  • [Cites] Bioinformatics. 2000 Apr;16(4):400-1 [10869039.001]
  • [Cites] AIDS. 2001 Aug 17;15(12):1453-60 [11504976.001]
  • [Cites] AIDS. 2002 May 24;16(8):1163-70 [12004275.001]
  • [Cites] J Acquir Immune Defic Syndr. 2003 Jul 1;33(3):336-42 [12843744.001]
  • [Cites] Nat Med. 2004 Mar;10(3):282-9 [14770175.001]
  • [Cites] Virology. 2005 Jun 5;336(2):137-43 [15892955.001]
  • [Cites] Antivir Ther. 2005;10(4):551-5 [16038481.001]
  • [Cites] J Clin Virol. 2006 Aug;36(4):264-71 [16765636.001]
  • [Cites] AIDS. 2006 Oct 24;20(16):W13-23 [17053344.001]
  • [Cites] Bioinformatics. 2006 Dec 15;22(24):3096-8 [17110367.001]
  • [Cites] Antivir Ther. 2007;12(2):247-52 [17503666.001]
  • [Cites] Arch Virol. 2007;152(10):1799-805 [17619115.001]
  • [Cites] Clin Vaccine Immunol. 2007 Oct;14(10):1266-73 [17715334.001]
  • [Cites] AIDS Res Hum Retroviruses. 2008 Jan;24(1):72-82 [18275350.001]
  • [Cites] PLoS Pathog. 2007 Jul;3(7):e94 [17616974.001]
  • [Cites] Mol Biol Evol. 1987 Jul;4(4):406-25 [3447015.001]
  • [Cites] Mol Biol Evol. 1993 May;10(3):512-26 [8336541.001]
  • [Cites] Annu Rev Pharmacol Toxicol. 1996;36:545-71 [8725401.001]
  • [Cites] J Virol. 1996 Dec;70(12):8270-6 [8970946.001]
  • [Cites] J Antimicrob Chemother. 1997 Jun;39(6):771-9 [9222047.001]
  • [Cites] N Engl J Med. 1998 Mar 26;338(13):853-60 [9516219.001]
  • [Cites] J Virol. 1999 Jul;73(7):6197-202 [10364383.001]
  • [Cites] J Virol. 2008 Jul;82(13):6434-46 [18434400.001]
  • (PMID = 20009919.001).
  • [ISSN] 1473-5571
  • [Journal-full-title] AIDS (London, England)
  • [ISO-abbreviation] AIDS
  • [Language] ENG
  • [Grant] United States / NIAID NIH HHS / AI / U01 AI043638-09; United States / NIAID NIH HHS / AI / R01 AI057167; United States / NIAID NIH HHS / AI / R21 AI077304; United States / NIDA NIH HHS / DA / K01 DA024654; United States / NIAID NIH HHS / AI / R01 AI047745; United States / NIAID NIH HHS / AI / AI036214-18; United States / NIAID NIH HHS / AI / UM1 AI069432; United States / NIAID NIH HHS / AI / AI047745; United States / NIAID NIH HHS / AI / AI36214; United States / NIMH NIH HHS / MH / MH083552; United States / NIAID NIH HHS / AI / R21 AI047745; United States / NIAID NIH HHS / AI / U01 AI069432; United States / NIAID NIH HHS / AI / AI74621; United States / NIAID NIH HHS / AI / P01 AI074621-030002; United States / NIAID NIH HHS / AI / U01 AI043638; United States / NIMH NIH HHS / MH / MH083552-03; United States / NIAID NIH HHS / AI / R56 AI047745; United States / NIAID NIH HHS / AI / AI047745-09; United States / NIMH NIH HHS / MH / P30 MH062512; United States / NIMH NIH HHS / MH / MH62512; United States / NIAID NIH HHS / AI / P30 AI036214; United States / NIAID NIH HHS / AI / R21 AI077304-02; United States / NIAID NIH HHS / AI / P30 AI036214-18; United States / NIMH NIH HHS / MH / R01 MH083552; United States / NIAID NIH HHS / AI / AI57167; United States / NIAID NIH HHS / AI / AI074621-030002; United States / NIAID NIH HHS / AI / AI43638; United States / NIMH NIH HHS / MH / R01 MH083552-03; United States / NIAID NIH HHS / AI / AI077304; United States / NIAID NIH HHS / AI / AI47745; United States / NIAID NIH HHS / AI / AI69432; United States / NIAID NIH HHS / AI / P01 AI074621; United States / NIAID NIH HHS / AI / AI043638-09; United States / NIAID NIH HHS / AI / R01 AI047745-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Retroviral Agents; EC 3.4.23.- / HIV Protease
  • [Other-IDs] NLM/ NIHMS223527; NLM/ PMC2913588
  •  go-up   go-down


5. Yaşar Işcan M, Steyn M: Craniometric determination of population affinity in South Africans. Int J Legal Med; 1999;112(2):91-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniometric determination of population affinity in South Africans.
  • A vital aspect of skeletal analysis is the determination of population affinity of an unknown individual.
  • Prediction accuracy was considerably lower when North American based formulae were tested on the South Africans, indicating significant craniometric differences between these populations.
  • [MeSH-major] African Continental Ancestry Group. Cephalometry. European Continental Ancestry Group

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 10048665.001).
  • [ISSN] 0937-9827
  • [Journal-full-title] International journal of legal medicine
  • [ISO-abbreviation] Int. J. Legal Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] GERMANY
  •  go-up   go-down


6. Lane AB, Soodyall H, Arndt S, Ratshikhopha ME, Jonker E, Freeman C, Young L, Morar B, Toffie L: Genetic substructure in South African Bantu-speakers: evidence from autosomal DNA and Y-chromosome studies. Am J Phys Anthropol; 2002 Oct;119(2):175-85
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The extent of genetic differentiation between seven South African Bantu-speaking groups (Zulu, Xhosa, Tsonga/Shangaan, Southern Sotho, Pedi, Tswana, and Venda) was assessed from coancestry coefficients (F(ST)) estimated from autosomal serogenetic, DNA, and Y-chromosome DNA haplotypes.
  • The genetic relationships between groups examined were inferred from their cluster affinities in phylogenetic trees constructed from the genetic distances between them.
  • Both autosomal and Y-chromosome DNA studies reveal that 6 of the 7 South African Bantu-speaking groups cluster according to their linguistic groupings, the exception being the Tsonga, who do not cluster with other Nguni language speakers, but rather with the Venda who live close to them.
  • This suggests that the invading Shangaan-speakers, whose Nguni language was adopted by the Tsonga, did not have a major effect on the Tsonga gene pool, and that gene flow from the Venda into the Tsonga may have been considerable.
  • Genetic distances were found to correlate with geographic distances between the regions where each group's apparent population density is the highest.
  • Together, these results suggest that linguistic and some genetic differentiation took place before the groups (or their forerunners) reached their present-day locations, and that further genetic change occurred after their arrival.
  • [MeSH-major] African Continental Ancestry Group / genetics. Chromosomes, Human, Y / genetics. DNA / genetics. Language
  • [MeSH-minor] Adult. Alleles. Female. Gene Frequency. Genetics, Population. Geography. Haplotypes. Humans. Linguistics. Male. South Africa

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2002 Wiley-Liss, Inc.
  • (PMID = 12237937.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-49-2 / DNA
  •  go-up   go-down


7. Lim KP, Chun NA, Gan CP, Teo SH, Rahman ZA, Abraham MT, Zain RB, Ponniah S, Cheong SC: Identification of immunogenic MAGED4B peptides for vaccine development in oral cancer immunotherapy. Hum Vaccin Immunother; 2014;10(11):3214-23
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this study, we have identified 9 short peptides derived from MAGED4B protein that are restricted in binding to the HLA subtypes common in the Asian population (HLA-A2, A11, and A24).
  • The peptides had good binding affinity with the MHC-Class I molecules and stimulated ex-vivo IFN-gamma and Granzyme-B production in blood samples from OSCC patients, suggesting that they are immunogenic.
  • [MeSH-minor] Adult. Asian Continental Ancestry Group. Cell Line, Tumor. Cell Movement. Cell Proliferation. Dendritic Cells / immunology. Female. Granzymes / biosynthesis. Granzymes / immunology. HLA-A11 Antigen / immunology. HLA-A2 Antigen / immunology. HLA-A24 Antigen / immunology. Humans. Interferon-gamma / biosynthesis. Interferon-gamma / immunology. Lymphocyte Activation / immunology. Male. Middle Aged

  • Genetic Alliance. consumer health - Oral cancer.
  • MedlinePlus Health Information. consumer health - Oral Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer Res. 2001 Jun 15;61(12):4809-14 [11406556.001]
  • [Cites] Head Neck. 2012 Aug;34(8):1123-8 [22083937.001]
  • [Cites] Head Neck. 2003 Mar;25(3):198-209 [12599287.001]
  • [Cites] Tissue Antigens. 2003 May;61(5):403-7 [12753660.001]
  • [Cites] J Clin Immunol. 2004 Jul;24(4):449-61 [15163902.001]
  • [Cites] CA Cancer J Clin. 1989 Mar-Apr;39(2):67-88 [2495159.001]
  • [Cites] J Am Dent Assoc. 1990 May;120(5):495-9 [2335670.001]
  • [Cites] Eur J Immunol. 1993 Jun;23(6):1215-9 [7684681.001]
  • [Cites] J Natl Cancer Inst. 1997 Feb 19;89(4):293-300 [9048833.001]
  • [Cites] Laryngoscope. 1998 Feb;108(2):250-6 [9473077.001]
  • [Cites] Int J Cancer. 1999 Jan 18;80(2):219-30 [9935203.001]
  • [Cites] Lung Cancer. 2006 Jan;51(1):79-88 [16225959.001]
  • [Cites] Leuk Res. 2006 Oct;30(10):1293-8 [16533527.001]
  • [Cites] Int J Mol Med. 2007 Mar;19(3):453-60 [17273794.001]
  • [Cites] Immunopharmacol Immunotoxicol. 2007;29(1):95-104 [17464770.001]
  • [Cites] Singapore Med J. 2007 Jul;48(7):632-4 [17609824.001]
  • [Cites] Asian Pac J Allergy Immunol. 2007 Mar;25(1):47-51 [17891921.001]
  • [Cites] J Immunother. 2007 Nov-Dec;30(8):847-54 [18049337.001]
  • [Cites] Nat Rev Immunol. 2009 Jan;9(1):57-62 [19104499.001]
  • [Cites] Oral Oncol. 2009 Aug;45(8):712-9 [19147396.001]
  • [Cites] Cancer Sci. 2009 Aug;100(8):1502-9 [19459850.001]
  • [Cites] Clin Lung Cancer. 2009 Sep;10(5):371-4 [19808198.001]
  • [Cites] J Am Coll Surg. 2010 Feb;210(2):140-7 [20113933.001]
  • [Cites] N Engl J Med. 2010 Jul 29;363(5):411-22 [20818862.001]
  • [Cites] Int J Cancer. 2010 Dec 15;127(12):2893-917 [21351269.001]
  • [Cites] CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90 [21296855.001]
  • [Cites] Int J Cancer. 2011 Nov 15;129(10):2427-34 [21207413.001]
  • [Cites] PLoS One. 2011;6(9):e24852 [21935482.001]
  • [Cites] Cancer Sci. 2012 Jan;103(1):150-3 [22221328.001]
  • [Cites] Int J Mol Med. 2012 Apr;29(4):656-62 [22294213.001]
  • [Cites] Int J Cancer. 2012 May 1;130(9):1991-2002 [21618523.001]
  • [Cites] Cancer Lett. 2012 Aug 1;321(1):18-26 [22459352.001]
  • [Cites] Cancer Lett. 2012 Sep 1;322(1):86-91 [22366580.001]
  • [Cites] Br J Cancer. 2012 Jun 26;107(1):116-22 [22596240.001]
  • [Cites] Tokai J Exp Clin Med. 2012 Jul;37(2):57-61 [22763829.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10290-5 [11517302.001]
  • (PMID = 25483651.001).
  • [ISSN] 2164-554X
  • [Journal-full-title] Human vaccines & immunotherapeutics
  • [ISO-abbreviation] Hum Vaccin Immunother
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Cancer Vaccines; 0 / HLA-A11 Antigen; 0 / HLA-A2 Antigen; 0 / HLA-A24 Antigen; 0 / MAGE-E1 antigen, human; 82115-62-6 / Interferon-gamma; EC 3.4.21.- / Granzymes
  • [Other-IDs] NLM/ PMC4517457
  • [Keywords] NOTNLM ; APC, antigen presenting cell / DC, dendritic cell / HC, healthy control / HLA, human leukocyte antigen / MAGED4B / MAGED4B, melanoma-associated antigen D4B / MHC, major histocompatibility complex / OSCC, oral squamous cell carcinoma / PBMC, peripheral blood mononuclear cell / immune system / immunotherapy / oral cancer / peptide vaccine
  •  go-up   go-down


8. Kruse S, Mao XQ, Heinzmann A, Blattmann S, Roberts MH, Braun S, Gao PS, Forster J, Kuehr J, Hopkin JM, Shirakawa T, Deichmann KA: The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma. Am J Hum Genet; 2000 May;66(5):1522-30
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our aim was to look for further PAFAH variants in white populations, their possible association with atopic and asthmatic phenotypes, and their functional importance.
  • The known loss-of-function mutations were not seen.
  • The variant allele Thr198 was found to be highly associated with total IgE concentrations in an atopic population (P=.009) and with "atopic asthma" in an asthmatic population (P=.008).
  • The variant allele Val379 was found to be highly associated with "specific sensitization" in the atopic population (P=.002) and with "asthma" in the asthmatic population (P=.003).
  • Thr198 and Val379 influence plasmatic PAFAH toward lower substrate affinities and therefore are very likely to prolong the activities of PAF.
  • Thus, two PAFAH variants seem to play a key role in atopic and asthmatic processes in Caucasian populations.
  • [MeSH-minor] 1-Alkyl-2-acetylglycerophosphocholine Esterase. Adolescent. Adult. Alleles. Case-Control Studies. Catalysis. Child. European Continental Ancestry Group / genetics. Exons / genetics. Gene Frequency / genetics. Genetic Predisposition to Disease / genetics. Genetic Variation / genetics. Humans. Immunoglobulin E / analysis. Kinetics. Linkage Disequilibrium / genetics. Phenotype. Polymorphism, Genetic / genetics. Recombinant Proteins / antagonists & inhibitors. Recombinant Proteins / genetics. Recombinant Proteins / isolation & purification. Recombinant Proteins / metabolism


9. Wang J, Li C, Wan F, Li Z, Zhang J, Zhang J, Feng X, Tang L, Chen B: The rs1550117 A>G variant in DNMT3A gene promoter significantly increases non-small cell lung cancer susceptibility in a Han Chinese population. Oncotarget; 2017 Apr 04;8(14):23470-23478
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The rs1550117 A>G variant in DNMT3A gene promoter significantly increases non-small cell lung cancer susceptibility in a Han Chinese population.
  • In this study, we conducted a case-control study to explore the association between rs1550117 A>G variant of DNMT3A gene promoter and non-small cell lung cancer (NSCLC) susceptibility in a Han Chinese population.
  • Additional functional analysis revealed that the increased binding affinity of transcription repressor SP1, which was associated with allele G of rs1550117, led to the significant decreased expression of DNMT3A.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Alleles. Asian Continental Ancestry Group / genetics. Case-Control Studies. China. Female. Gene Frequency. Genotype. Humans. Male. Middle Aged. Polymerase Chain Reaction. Polymorphism, Restriction Fragment Length. Protein Binding. Risk Factors. Sp1 Transcription Factor / metabolism. Young Adult

  • Genetic Alliance. consumer health - Lung Cancer.
  • Genetic Alliance. consumer health - Non-small cell lung cancer.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2010 Dec 16;363(25):2424-33 [21067377.001]
  • [Cites] Thorac Cancer. 2015 Mar;6(2):209-15 [26273360.001]
  • [Cites] Genet Mol Res. 2012 Dec 17;11(4):4330-41 [23079992.001]
  • [Cites] Biomed Rep. 2013 Jul;1(4):664-668 [24649006.001]
  • [Cites] Curr Opin Hematol. 2007 Mar;14(2):85-9 [17255784.001]
  • [Cites] Blood. 2012 Jan 12;119(2):559-68 [22077061.001]
  • [Cites] PLoS Genet. 2012;8(12):e1003146 [23284304.001]
  • [Cites] N Engl J Med. 2008 Sep 25;359(13):1367-80 [18815398.001]
  • [Cites] Nucleic Acids Res. 1988 Feb 11;16(3):1215 [3344216.001]
  • [Cites] Oncol Lett. 2012 Feb;3(2):450-454 [22740930.001]
  • [Cites] N Engl J Med. 2008 Mar 13;358(11):1148-59 [18337604.001]
  • [Cites] Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18061-6 [22011581.001]
  • [Cites] PLoS One. 2014 Aug 15;9(8):e104968 [25126948.001]
  • [Cites] Haematologica. 2012 Feb;97(2):246-50 [21993668.001]
  • [Cites] Nat Genet. 2011 Mar 29;43(4):289-90 [21445072.001]
  • [Cites] Nat Rev Genet. 2007 Apr;8(4):286-98 [17339880.001]
  • [Cites] Trends Genet. 2012 Oct;28(10):474-9 [22704242.001]
  • [Cites] Leukemia. 2012 May;26(5):1106-7 [22124213.001]
  • [Cites] Asian Pac J Cancer Prev. 2013;14(10):5713-8 [24289567.001]
  • [Cites] J Invest Surg. 2015;28(6):346-53 [26203494.001]
  • [Cites] CA Cancer J Clin. 2015 Jan-Feb;65(1):5-29 [25559415.001]
  • [Cites] Methods Mol Biol. 2009;578:3-22 [19768584.001]
  • [Cites] BMC Med. 2010 Feb 03;8:12 [20128888.001]
  • [Cites] Nat Genet. 2011 Mar 13;43(4):309-15 [21399634.001]
  • [Cites] Int J Mol Sci. 2012;13(7):8364-78 [22942708.001]
  • [Cites] Adv Genet. 2010;70:247-76 [20920751.001]
  • [Cites] Mol Biol Rep. 2013 Aug;40(8):4893-9 [23666104.001]
  • [Cites] Genome Res. 2009 Dec;19(12):2163-71 [19801529.001]
  • [Cites] Biochem Biophys Res Commun. 2009 Sep 25;387(3):611-6 [19632198.001]
  • [Cites] Genet Mol Res. 2015 Apr 17;14(2):3640-9 [25966133.001]
  • [Cites] J Biomed Biotechnol. 2010;2010:737535 [20467490.001]
  • [Cites] Biochem J. 2005 Jan 15;385(Pt 2):557-64 [15362956.001]
  • (PMID = 28423585.001).
  • [ISSN] 1949-2553
  • [Journal-full-title] Oncotarget
  • [ISO-abbreviation] Oncotarget
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Sp1 Transcription Factor; EC 2.1.1.37 / DNA (Cytosine-5-)-Methyltransferase; EC 2.1.1.37 / DNA methyltransferase 3A
  • [Keywords] NOTNLM ; DNMT3A / Han Chinese population / non-small cell lung cancer / rs1550117
  •  go-up   go-down


10. Nakashima A, Ishida H, Shigematsu M, Goto M, Hanihara T: Nonmetric cranial variation of Jomon Japan: Implications for the evolution of eastern Asian diversity. Am J Hum Biol; 2010 Nov-Dec;22(6):782-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: The purpose of this study is to investigate the origin and expansion of the Jomon population, the Neolithic inhabitants of the Japanese archipelago, and peopling East/Northeast Asian region through a global comparison between the prehistoric samples from around the world.
  • METHODS: R-matrix approach was applied to 20 nonmetric cranial traits for assessing the population structure and history of the Jomon.
  • Pattern of ancient group relationships on a global scale was presented using network splitstree applied to distance matrix transformed from the R-matrix.
  • Global analyses including samples from Northeast Asia, Southeast Asia, Australia, West Asia, Europe, and North Africa dating roughly to the same chronological periods as those of the Jomon groups, indicate northern affinities of the Jomon and the distinction between Southeast and Northeast Asian series.
  • A possible gene flow from outside source or heterogeneous origin of western Jomon group was, at the same time, suggested.
  • The network relationships of the Jomon with Northeast Asians and, to a lesser extent, with Southeast Asians based on the splitstree analysis may allow us to suppose that the Jomon may be one of the key populations for the studies of the evolution of eastern Asian diversity.
  • [MeSH-major] Asian Continental Ancestry Group. Biological Evolution. Skull / anatomy & histology
  • [MeSH-minor] Gene Flow. Humans. Japan. Phenotype. Population Density

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 Wiley-Liss, Inc.
  • (PMID = 20721979.001).
  • [ISSN] 1520-6300
  • [Journal-full-title] American journal of human biology : the official journal of the Human Biology Council
  • [ISO-abbreviation] Am. J. Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  •  go-up   go-down


11. Gauniyal M, Aggarwal A, Kshatriya GK: Genomic structure of the immigrant Siddis of East Africa to southern India: a study of 20 autosomal DNA markers. Biochem Genet; 2011 Aug;49(7-8):427-42
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Siddis are a tribal group of African origin living in Karnataka, India.
  • They have undergone considerable cultural change due to their proximity to neighboring population groups.
  • To understand the biological consequences of these changes, we describe the genomic structure of the Siddis and the contribution from putative ancestral populations using 20 autosomal DNA markers.
  • The distribution of Alu indel markers and a genetic distance analysis reveals their closer affinities with Africans.
  • The levels of genomic diversity and heterozygosity are high in all the populations of southern India.
  • The genetic homogeneity of the Siddis, in spite of its admixed origin, suggests the utility of this population for genetic epidemiological studies.
  • [MeSH-major] Ethnic Groups / genetics. Genetic Markers
  • [MeSH-minor] Africa, Eastern / ethnology. African Continental Ancestry Group / genetics. Emigrants and Immigrants. Europe / ethnology. European Continental Ancestry Group / genetics. Gene Flow. Gene Frequency. Genetic Variation. Genome, Human. Heterozygote. Humans. India. Polymorphism, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21274614.001).
  • [ISSN] 1573-4927
  • [Journal-full-title] Biochemical genetics
  • [ISO-abbreviation] Biochem. Genet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Genetic Markers
  •  go-up   go-down


12. Cao Y, Schmitz JL, Yang J, Hogan SL, Bunch D, Hu Y, Jennette CE, Berg EA, Arnett FC Jr, Jennette JC, Falk RJ, Preston GA: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. J Am Soc Nephrol; 2011 Jun;22(6):1161-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Anti-neutrophil cytoplasmic autoantibody (ANCA) disease rarely occurs in African Americans and risk factors for the disease in this population are unknown.
  • Furthermore, we found that DRB1*1501 protein binds with high affinity to amino acid sequences of sense-PR3, purportedly an antigenic epitope, and to the amino acid sequence complementary to this epitope in vitro.

  • MedlinePlus Health Information. consumer health - African American Health.
  • MedlinePlus Health Information. consumer health - Granulomatosis with Polyangiitis.
  • COS Scholar Universe. author profiles.
  • antibodies-online. View related products from antibodies-online.com (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Intern Med J. 2007 Apr;37(4):242-6 [17388864.001]
  • [Cites] Kidney Int. 2001 Jan;59(1):147-59 [11135067.001]
  • [Cites] Clin Exp Immunol. 2001 Jan;123(1):170-7 [11168015.001]
  • [Cites] Kidney Int. 2001 Dec;60(6):2247-62 [11737598.001]
  • [Cites] J Rheumatol. 2003 Mar;30(3):618-21 [12610825.001]
  • [Cites] Tissue Antigens. 2003 Mar;61(3):249-52 [12694574.001]
  • [Cites] Genes Immun. 2003 Jun;4(4):316-20 [12761569.001]
  • [Cites] Nat Med. 2004 Jan;10(1):72-9 [14661018.001]
  • [Cites] Arthritis Rheum. 2004 Feb 15;51(1):92-9 [14872461.001]
  • [Cites] Arthritis Rheum. 1983 Jan;26(1):102-5 [6130772.001]
  • [Cites] Ann Rheum Dis. 1986 May;45(5):417-21 [3718017.001]
  • [Cites] Br J Rheumatol. 1991 Apr;30(2):144-5 [2012946.001]
  • [Cites] Am J Hum Genet. 1989 Oct;45(4):541-6 [2491013.001]
  • [Cites] Kidney Int. 1992 Apr;41(4):1059-63 [1381003.001]
  • [Cites] J Immunol. 1993 Aug 1;151(3):1482-90 [8335942.001]
  • [Cites] J Immunol. 1994 May 1;152(9):4722-37 [8157982.001]
  • [Cites] Immunogenetics. 1995;41(4):178-228 [7890324.001]
  • [Cites] J Am Soc Nephrol. 1996 Jan;7(1):23-32 [8808106.001]
  • [Cites] J Am Soc Nephrol. 1996 Jan;7(1):33-9 [8808107.001]
  • [Cites] J Exp Med. 1998 Apr 6;187(7):1019-28 [9529318.001]
  • [Cites] Kidney Int. 1999 May;55(5):1811-8 [10231443.001]
  • [Cites] Am J Kidney Dis. 1999 Aug;34(2):364-73 [10430990.001]
  • [Cites] Ann Intern Med. 2005 Nov 1;143(9):621-31 [16263884.001]
  • [Cites] PLoS Comput Biol. 2008 Apr;4(4):e1000048 [18389056.001]
  • [Cites] Arthritis Rheum. 2008 Sep;58(9):2908-18 [18759282.001]
  • [Cites] Kidney Int. 2008 Nov;74(9):1159-69 [18596726.001]
  • [Cites] Immunology. 2006 Dec;119(4):562-71 [17034427.001]
  • [CommentIn] Nat Rev Nephrol. 2011 Aug;7(8):425 [21691319.001]
  • (PMID = 21617122.001).
  • [ISSN] 1533-3450
  • [Journal-full-title] Journal of the American Society of Nephrology : JASN
  • [ISO-abbreviation] J. Am. Soc. Nephrol.
  • [Language] ENG
  • [Grant] United States / NIAMS NIH HHS / AR / P60 AR047785; United States / NCRR NIH HHS / RR / U54 RR019497; United States / NIAMS NIH HHS / AR / R01AR047799; United States / NIDDK NIH HHS / DK / 2P01DK; United States / NIAMS NIH HHS / AR / U54 AR057319; United States / NIAMS NIH HHS / AR / AR-47785; United States / NIAMS NIH HHS / AR / R01 AR047799
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Epitopes; 0 / HLA-DR Antigens; 0 / HLA-DRB1 Chains; 0 / HLA-DRB1*15 antigen
  • [Other-IDs] NLM/ PMC3103736
  •  go-up   go-down


13. Cambra A, Muñoz-Saá I, Crespí C, Serra A, Etxagibel A, Matamoros N, Milà J, Julià MR: MICA-HLA-B haplotype diversity and linkage disequilibrium in a population of Jewish descent from Majorca (the Balearic Islands). Hum Immunol; 2009 Jul;70(7):513-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MICA-HLA-B haplotype diversity and linkage disequilibrium in a population of Jewish descent from Majorca (the Balearic Islands).
  • This allelic variation may influence the affinity of MICA molecules to their receptor on natural killer, gammadelta T and CD8+ T cells, NKG2D, and the immune response to organ transplantation and disease susceptibility.
  • In the present study, we typed MICA and HLA-B polymorphisms in 95 individuals from a population of Jewish descent (Chuetas) and 195 individuals of Caucasian origin from Majorca (the Balearic Islands).
  • Both populations presented haplotypes with significant LD that were shared by other Caucasians populations, but we reported particular haplotypes in the Chueta group: MICA*002-HLA-B*38, MICA*016-HLA-B*35, MICA*012-HLA-B*55, and MICA*017-HLA-B*57.
  • These haplotypes were not reported in other studies at high frequencies.
  • In conclusion, the Chueta population presents a particular genetic pool but has affinities with the host population.
  • [MeSH-minor] European Continental Ancestry Group / genetics. Gene Frequency. Genetic Variation. Humans. Polymorphism, Genetic. Spain

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19364518.001).
  • [ISSN] 1879-1166
  • [Journal-full-title] Human immunology
  • [ISO-abbreviation] Hum. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HLA-B Antigens; 0 / Histocompatibility Antigens Class I; 0 / MHC class I-related chain A
  •  go-up   go-down


14. Chen Z, Zhang Y, Fan A, Zhang Y, Wu Y, Zhao Q, Zhou Y, Zhou C, Bawudong M, Mao X, Ma Y, Yang L, Ding Y, Wang X, Rao S: Brief communication: Y-chromosome haplogroup analysis indicates that Chinese Tuvans share distinctive affinity with Siberian Tuvans. Am J Phys Anthropol; 2011 Mar;144(3):492-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brief communication: Y-chromosome haplogroup analysis indicates that Chinese Tuvans share distinctive affinity with Siberian Tuvans.
  • The Tuvans in China were classified as Mongolians in the early 1950s by the National Ethnic Affairs Commission of China, but they defined themselves as a separate group.
  • These haplogroup data were combined with public data for 15 populations in South Siberia and Central Asia.
  • Further population tree analysis revealed that Tuvans were on a far-separated cluster from their neighbors.
  • Based on these results, we propose that the Tuvans (in both China and the Republic of Tuva) constitute a group distinct from Mongolians and from other Central Asia populations.
  • However, the genetic results might be the consequence of some evolutionary forces like genetic drift and founder effect, and do not necessarily reflect their ultimate origin.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Chromosomes, Human, Y. Haplotypes / genetics. Molecular Epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Analysis of Variance. Child. China / ethnology. Cluster Analysis. Genetics, Population. Humans. Male. Middle Aged. Polymorphism, Restriction Fragment Length. Principal Component Analysis. Siberia / ethnology. Transients and Migrants

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2011 Wiley-Liss, Inc.
  • (PMID = 21302276.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  •  go-up   go-down


15. Ricaut FX, Keyser-Tracqui C, Cammaert L, Crubézy E, Ludes B: Genetic analysis and ethnic affinities from two Scytho-Siberian skeletons. Am J Phys Anthropol; 2004 Apr;123(4):351-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic analysis and ethnic affinities from two Scytho-Siberian skeletons.
  • We extracted DNA from two skeletons belonging to the Sytho-Siberian population, which were excavated from the Sebÿstei site (dating back 2,500 years) in the Altai Republic (Central Asia).
  • The results showed that these two skeletons were not close relatives.
  • Moreover, their haplogroups were characteristic of Asian populations.
  • Comparison with the haplogroup of 3,523 Asian and American individuals linked one skeleton with a putative ancestral paleo-Asiatic population and the other with Chinese populations.
  • It appears that the genetic study of ancient populations of Central Asia brings important elements to the understanding of human population movements in Asia.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Ethnic Groups / genetics. Fossils. Genetic Variation / genetics. Skeleton

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2003 Wiley-Liss, Inc.
  • (PMID = 15022363.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


16. Marchani EE, Watkins WS, Bulayeva K, Harpending HC, Jorde LB: Culture creates genetic structure in the Caucasus: autosomal, mitochondrial, and Y-chromosomal variation in Daghestan. BMC Genet; 2008 Jul 17;9:47
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • While the Caucasus Mountains have diverted human traffic to the few lowland regions that provide a gateway from north to south between the Caspian and Black Seas, highland populations have been isolated by their remote geographic location and their practice of patrilocal endogamy.
  • We investigate how these cultural and historical differences between highland and lowland populations have affected patterns of genetic diversity.
  • We test 1) whether the highland practice of patrilocal endogamy has generated sex-specific population relationships, and 2) whether the history of migration and military conquest associated with the lowland populations has left Central Asian genes in the Caucasus, by comparing genetic diversity and pairwise population relationships between Daghestani populations and reference populations throughout Europe and Asia for autosomal, mitochondrial, and Y-chromosomal markers.
  • RESULTS: We found that the highland Daghestani populations had contrasting histories for the mitochondrial DNA and Y-chromosome data sets.
  • Y-chromosomal haplogroup diversity was reduced among highland Daghestani populations when compared to other populations and to highland Daghestani mitochondrial DNA haplogroup diversity.
  • Lowland Daghestani populations showed Turkish and Central Asian affinities for both mitochondrial and Y-chromosomal data sets.
  • Autosomal population histories are strongly correlated to the pattern observed for the mitochondrial DNA data set, while the correlation between the mitochondrial DNA and Y-chromosome distance matrices was weak and not significant.
  • CONCLUSION: The reduced Y-chromosomal diversity exhibited by highland Daghestani populations is consistent with genetic drift caused by patrilocal endogamy.
  • Mitochondrial and Y-chromosomal phylogeographic comparisons indicate a common Near Eastern origin of highland populations.
  • Lowland Daghestani populations show varying influence from Near Eastern and Central Asian populations.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Phys Anthropol. 2005 Dec;128(4):846-54 [16028228.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 May 24;102(21):7476-80 [15894624.001]
  • [Cites] Am J Hum Biol. 2006 Sep-Oct;18(5):610-20 [16917895.001]
  • [Cites] Am J Hum Genet. 2007 Jan;80(1):29-43 [17160892.001]
  • [Cites] Hum Biol. 2006 Aug;78(4):465-76 [17278621.001]
  • [Cites] PLoS Genet. 2007 Jun;3(6):e104 [17604454.001]
  • [Cites] Annu Rev Genet. 2007;41:539-64 [18076332.001]
  • [Cites] Hum Biol. 2003 Dec;75(6):837-53 [15018034.001]
  • [Cites] Am J Hum Genet. 2004 May;74(5):827-45 [15077202.001]
  • [Cites] Eur J Hum Genet. 2004 Jun;12(6):495-504 [14872198.001]
  • [Cites] Ann Hum Genet. 2004 May;68(Pt 3):205-21 [15180701.001]
  • [Cites] Hum Genet. 2004 Aug;115(3):221-9 [15232732.001]
  • [Cites] Proc Biol Sci. 2001 Jun 7;268(1472):1197-206 [11375109.001]
  • [Cites] Mol Biol Evol. 2001 Jul;18(7):1189-203 [11420360.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10244-9 [11526236.001]
  • [Cites] Nat Genet. 2001 Sep;29(1):20-1 [11528385.001]
  • [Cites] Genome Res. 2002 Feb;12(2):339-48 [11827954.001]
  • [Cites] Am J Hum Genet. 2002 Apr;70(4):1009-14 [11845409.001]
  • [Cites] Am J Hum Genet. 2002 Nov;71(5):1168-74 [12355353.001]
  • [Cites] Genome Res. 2003 Jul;13(7):1607-18 [12805277.001]
  • [Cites] Nat Rev Genet. 2003 Aug;4(8):598-612 [12897772.001]
  • [Cites] Hum Genet. 2004 Jan;114(2):127-48 [14586639.001]
  • [Cites] Cold Spring Harb Symp Quant Biol. 2003;68:487-93 [15338652.001]
  • [Cites] Mol Biol (Mosk). 2004 Jul-Aug;38(4):617-24 [15456133.001]
  • [Cites] Mol Biol Evol. 2004 Dec;21(12):2265-80 [15317881.001]
  • [Cites] Hum Biol. 1994 Aug;66(4):639-68 [8088752.001]
  • [Cites] Nat Genet. 1998 Nov;20(3):278-80 [9806547.001]
  • [Cites] Ann Hum Genet. 2004 Nov;68(Pt 6):588-99 [15598217.001]
  • [Cites] Am J Hum Genet. 2006 Apr;78(4):564-74 [16532388.001]
  • (PMID = 18637195.001).
  • [ISSN] 1471-2156
  • [Journal-full-title] BMC genetics
  • [ISO-abbreviation] BMC Genet.
  • [Language] ENG
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM059290; United States / NIGMS NIH HHS / GM / GM-59290
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  • [Other-IDs] NLM/ PMC2488347
  •  go-up   go-down


17. Da Luz J, Kimura EM, Costa FF, Sonati Mde F, Sans M: Beta-globin gene cluster haplotypes in Afro-Uruguayans from two geographical regions (South and North). Am J Hum Biol; 2010 Jan-Feb;22(1):124-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The beta-globin gene cluster haplotypes were identified in 52 and 40 chromosomes from two Afro-Uruguayan populations located in the South and North of the country, respectively.
  • In both regions, the 5' haplotype 2 (+ - - - -), characteristic of non-African populations, was the most frequent, reflecting a strong process of admixture in Afro-Uruguayans (0.355 and 0.262, respectively).
  • The haplotypes 3 (- - - - +) and 4 (- + - - +), characteristics of African sub-Saharan populations, present inverse frequencies in North and South: whereas in the South haplotype 3 is the second most frequent (0.232), and haplotype 4 presents a low frequency (0.019), in the North haplotype 4 is the third most frequent (0.140), and haplotype 3 only reaches an intermediate frequency (0.088).
  • Nei's genetic distance show that South and North present affinities with Bantu groups, although the North present the smallest genetic distance with the Mandenka, a Senegalese population.
  • With respect to 3' haplotypes, haplotype I was the most frequent in both populations, followed by haplotype II, characteristic of sub-Saharan Africans.
  • The high frequencies of haplotype III-Asian could indicate admixture with Native American populations.
  • [MeSH-major] African Continental Ancestry Group / genetics. Haplotypes. Multigene Family. beta-Globins / genetics
  • [MeSH-minor] Genetics, Population. Humans. Uruguay / ethnology

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19533614.001).
  • [ISSN] 1520-6300
  • [Journal-full-title] American journal of human biology : the official journal of the Human Biology Council
  • [ISO-abbreviation] Am. J. Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / beta-Globins
  •  go-up   go-down


18. Zhang X, Zhang W, Qiu D, Sandford A, Tan WC: The E237G polymorphism of the high-affinity IgE receptor beta chain and asthma. Ann Allergy Asthma Immunol; 2004 Nov;93(5):499-503
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The E237G polymorphism of the high-affinity IgE receptor beta chain and asthma.
  • BACKGROUND: The beta chain of high-affinity IgE receptor (FcepsilonRI beta) has been proposed as a candidate gene for asthma and atopic diseases.
  • OBJECTIVES: To determine the prevalence of the E237G polymorphism of the FcepsilonRI beta gene and to investigate its association with asthma and total IgE levels in 3 Asian populations.
  • Genotypes with the G allele were more prevalent in asthmatic patients in the Chinese population (odds ratio, 1.97; 95% confidence interval, 1.05-3.77; P = .04).
  • CONCLUSIONS: There were interethnic differences in the frequencies of the G variant among Chinese, Malay, and Indian populations.
  • The E237G polymorphism of FcsRI beta may be a risk factor for asthma in the Chinese population.
  • [MeSH-minor] Adult. Aged. Asian Continental Ancestry Group. Female. Gene Frequency. Humans. Male. Middle Aged

  • Genetic Alliance. consumer health - Asthma.
  • MedlinePlus Health Information. consumer health - Asthma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15562891.001).
  • [ISSN] 1081-1206
  • [Journal-full-title] Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • [ISO-abbreviation] Ann. Allergy Asthma Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, IgE
  •  go-up   go-down


19. Esau L, Kaur M, Adonis L, Arieff Z: The 5-HTTLPR polymorphism in South African healthy populations: a global comparison. J Neural Transm (Vienna); 2008 May;115(5):755-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The 5-HTTLPR polymorphism in South African healthy populations: a global comparison.
  • Having a high affinity for the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT), serotonin transporter controls the duration, availability and signaling capacity of 5-HT in the synapse.
  • Association studies have focused extensively on this polymorphic region as the frequencies of long- and short-alleles of this gene differ greatly amongst populations and association studies have either reported conflicting results or nothing significant at all.
  • Cheek cell samples were collected from the three major ethnic groups namely: Caucasians, Africans and coloreds/Mixed population.
  • Genotypes were compared amongst the three major ethnic groups from SA as well as to that of other studies around the world.
  • This is the first study to report significant differences in the 5-HTTLPR genotype and allelic frequencies among various ethnic groups in SA.
  • Future studies will target larger population groups and the estimation of frequency of these alleles in individuals with autism.
  • [MeSH-major] African Continental Ancestry Group / genetics. Polymorphism, Genetic / genetics. Population / genetics. Serotonin Plasma Membrane Transport Proteins / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Neurosci. 2005 Mar 9;25(10):2586-90 [15758168.001]
  • [Cites] Biol Psychiatry. 2006 Jul 15;60(2):186-91 [16616719.001]
  • [Cites] Brain Res. 2006 May 30;1092(1):28-35 [16674932.001]
  • [Cites] Am J Hum Genet. 2006 May;78(5):815-26 [16642437.001]
  • [Cites] Neuropsychopharmacology. 2000 Nov;23(5):587-90 [11027924.001]
  • [Cites] Mol Interv. 2004 Apr;4(2):109-23 [15087484.001]
  • [Cites] Biopsychosoc Med. 2007 Jan 10;1:3 [17371573.001]
  • [Cites] Mol Psychiatry. 2002;7(10):1115-9 [12476327.001]
  • [Cites] Am J Psychiatry. 2004 Mar;161(3):569-72 [14992987.001]
  • [Cites] Genome Res. 1997 Nov;7(11):1061-71 [9371742.001]
  • [Cites] J Psychopharmacol. 2006 May;20(3):389-99 [16574713.001]
  • [Cites] Neuropsychopharmacology. 2003 Mar;28(3):533-41 [12629534.001]
  • [Cites] Biol Psychiatry. 2003 Nov 1;54(9):884-9 [14573315.001]
  • [Cites] Hum Mol Genet. 1997 Dec;6(13):2233-8 [9361027.001]
  • [Cites] Int J Dev Neurosci. 2005 Apr-May;23(2-3):221-34 [15749247.001]
  • [Cites] Trends Cogn Sci. 2006 Apr;10(4):182-91 [16530463.001]
  • [Cites] Am J Psychiatry. 2003 Apr;160(4):671-6 [12668354.001]
  • [Cites] J Hum Genet. 1999;44(1):15-7 [9929970.001]
  • [Cites] Am J Psychiatry. 2006 Jun;163(6):1103-5 [16741214.001]
  • [Cites] Mol Psychiatry. 1997 May;2(3):247-50 [9152989.001]
  • [Cites] Am J Pharmacogenomics. 2003;3(2):145-7 [12749731.001]
  • [Cites] Am J Psychiatry. 2007 Sep;164(9):1379-84 [17728423.001]
  • [Cites] J Neural Transm (Vienna). 2003 Apr;110(4):345-51 [12658362.001]
  • (PMID = 18193379.001).
  • [ISSN] 0300-9564
  • [Journal-full-title] Journal of neural transmission (Vienna, Austria : 1996)
  • [ISO-abbreviation] J Neural Transm (Vienna)
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / SLC6A4 protein, human; 0 / Serotonin Plasma Membrane Transport Proteins
  •  go-up   go-down


20. Haber M, Gauguier D, Youhanna S, Patterson N, Moorjani P, Botigué LR, Platt DE, Matisoo-Smith E, Soria-Hernanz DF, Wells RS, Bertranpetit J, Tyler-Smith C, Comas D, Zalloua PA: Genome-wide diversity in the levant reveals recent structuring by culture. PLoS Genet; 2013;9(2):e1003316
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this study we analyze more than 500,000 genome-wide SNPs in 1,341 new samples from the Levant and compare them to samples from 48 populations worldwide.
  • Our results show recent genetic stratifications in the Levant are driven by the religious affiliations of the populations within the region.
  • Cultural changes within the last two millennia appear to have facilitated/maintained admixture between culturally similar populations from the Levant, Arabian Peninsula, and Africa.
  • The same cultural changes seem to have resulted in genetic isolation of other groups by limiting admixture with culturally different neighboring populations.
  • Consequently, Levant populations today fall into two main groups: one sharing more genetic characteristics with modern-day Europeans and Central Asians, and the other with closer genetic affinities to other Middle Easterners and Africans.
  • [MeSH-major] Chromosomes, Human, Y / genetics. DNA, Mitochondrial / genetics. Genetic Variation. Genetics, Population
  • [MeSH-minor] African Continental Ancestry Group. Archaeology. Cultural Evolution. Ethnic Groups / genetics. European Continental Ancestry Group. Genome, Human. Haplotypes. Humans. Middle East. Phylogeny

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 2006 Mar;78(3):487-97 [16404693.001]
  • [Cites] Evol Anthropol. 2012 Mar;21(2):69-81 [22499441.001]
  • [Cites] PLoS Genet. 2006 Dec;2(12):e190 [17194218.001]
  • [Cites] Am J Hum Genet. 2007 Sep;81(3):559-75 [17701901.001]
  • [Cites] Nature. 2007 Oct 18;449(7164):851-61 [17943122.001]
  • [Cites] Nature. 2008 Feb 21;451(7181):998-1003 [18288195.001]
  • [Cites] Science. 2008 Feb 22;319(5866):1100-4 [18292342.001]
  • [Cites] Am J Hum Genet. 2008 Apr;82(4):873-82 [18374297.001]
  • [Cites] PLoS Genet. 2008 May;4(5):e1000078 [18497854.001]
  • [Cites] Am J Phys Anthropol. 2008;Suppl 47:70-99 [19003886.001]
  • [Cites] Nat Rev Genet. 2009 Sep;10(9):639-50 [19687804.001]
  • [Cites] Am J Hum Genet. 2012 May 4;90(5):915-24 [22560092.001]
  • [Cites] Annu Rev Genomics Hum Genet. 2012;13:337-61 [22703172.001]
  • [Cites] PLoS One. 2012;7(10):e45685 [23077494.001]
  • [Cites] Nat Genet. 2006 Nov;38(11):1251-60 [17057719.001]
  • [Cites] Genome Res. 2009 Sep;19(9):1655-64 [19648217.001]
  • [Cites] Ann Hum Genet. 2009 Nov;73(Pt 6):568-81 [19686289.001]
  • [Cites] Hum Genet. 2009 Nov;126(5):707-17 [19669163.001]
  • [Cites] PLoS Biol. 2010 Jan;8(1):e1000285 [20087410.001]
  • [Cites] Am J Hum Genet. 2010 Jun 11;86(6):850-9 [20560205.001]
  • [Cites] Nature. 2010 Jul 8;466(7303):238-42 [20531471.001]
  • [Cites] Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16222-7 [20798349.001]
  • [Cites] PLoS Biol. 2010;8(11):e1000536 [21085689.001]
  • [Cites] Eur J Hum Genet. 2011 Mar;19(3):334-40 [21119711.001]
  • [Cites] PLoS Genet. 2011 Apr;7(4):e1001373 [21533020.001]
  • [Cites] BMC Bioinformatics. 2011;12:246 [21682921.001]
  • [Cites] Genetics. 2012 Jan;190(1):159-74 [21868606.001]
  • [Cites] Nat Methods. 2012 Feb;9(2):179-81 [22138821.001]
  • [Cites] PLoS Genet. 2012 Jan;8(1):e1002453 [22291602.001]
  • [Cites] PLoS One. 2012;7(2):e31447 [22355366.001]
  • [Cites] Mol Biol Evol. 2004 Jul;21(7):1361-72 [15044595.001]
  • (PMID = 23468648.001).
  • [ISSN] 1553-7404
  • [Journal-full-title] PLoS genetics
  • [ISO-abbreviation] PLoS Genet.
  • [Language] eng
  • [Grant] United States / PEPFAR / / 098051; United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  • [Other-IDs] NLM/ PMC3585000
  •  go-up   go-down


21. Jiang YC, Kuang LL, Sun SN, Duan WY, Qiao B, Wang HY: Association of genetic polymorphisms of de novo nucleotide biosynthesis with increased CHD susceptibility in the northern Chinese population. Clin Genet; 2017 May;91(5):748-755
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of genetic polymorphisms of de novo nucleotide biosynthesis with increased CHD susceptibility in the northern Chinese population.
  • However, the underlying molecular mechanism(s) have not been fully understood.
  • Here we report that increased CHD susceptibility is associated with genetic polymorphisms for de novo nucleotide biosynthesis in northern Chinese population, which has been reported with lower plasma folate levels.
  • Nine tagSNPs of four genes (GART, ATIC, MTHFD1 and SHMT1) in de novo nucleotide biosynthesis were sequenced in 802 sporadic CHD patients and 1093 controls from two Han Chinese populations, located in north China (Shandong) and South China (Shanghai), respectively.
  • Six SNPs were found to be significantly associated with CHDs or septation defects only in the Shandong population dataset, but none displayed significant association with any CHDs in the Shanghai population dataset as well as in the combined dataset.
  • We also showed that the minor A allele of rs7279549 in GART reduced transcriptional activity and displayed lower affinity for unknown transcription factor(s), demonstrating the allele is a functional risk factor for CHD in Shandong population.
  • Our study indicates that dysregulation of de novo nucleotide biosynthesis pathway may conditionally contribute to CHD pathogenesis in northern Chinese.
  • [MeSH-minor] Alleles. Asian Continental Ancestry Group / genetics. Case-Control Studies. Genetic Predisposition to Disease. Humans. Nucleotides / biosynthesis. Nucleotides / genetics. Transcription Factors / genetics. Transcription Factors / metabolism

  • MedlinePlus Health Information. consumer health - Congenital Heart Defects.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
  • (PMID = 27659940.001).
  • [ISSN] 1399-0004
  • [Journal-full-title] Clinical genetics
  • [ISO-abbreviation] Clin. Genet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Minor Histocompatibility Antigens; 0 / Multienzyme Complexes; 0 / Nucleotides; 0 / Transcription Factors; 0 / inosine monophosphate synthase; EC 1.5.1.5 / MTHFD1 protein, human; EC 1.5.1.5 / Methylenetetrahydrofolate Dehydrogenase (NADP); EC 2.1.2.- / Hydroxymethyl and Formyl Transferases; EC 2.1.2.1 / Glycine Hydroxymethyltransferase; EC 2.1.2.1 / SHMT protein, human; EC 2.1.2.2 / Phosphoribosylglycinamide Formyltransferase; EC 3.5.4.- / Nucleotide Deaminases; EC 6.3.- / Carbon-Nitrogen Ligases; EC 6.3.4.13 / GART protein, human
  • [Keywords] NOTNLM ; congenital heart diseases / de novo nucleotide biosynthesis / genetic polymorphism
  •  go-up   go-down


22. Yang J, Lu MM, Lu YW, Feng CC, Leng RX, Pan HF, Ye DQ: Sex-specific differences in the relationship between the single-nucleotide polymorphism rs2298804 of FCER1A and the susceptibility to systemic lupus erythematosus in a Chinese Han population. Clin Exp Dermatol; 2013 Jun;38(4):410-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sex-specific differences in the relationship between the single-nucleotide polymorphism rs2298804 of FCER1A and the susceptibility to systemic lupus erythematosus in a Chinese Han population.
  • A recent study identified the high-affinity IgE receptor α-chain (FcεRIα) gene FCER1A as a susceptibility locus influencing total serum IgE levels.
  • AIM: To investigate whether the single-nucleotide polymorphism (SNP) rs2298804 (251 A>G) of FCER1A is associated with SLE and its clinical characteristics in a Chinese Han population.
  • Although we did not find any significant correlation between the rs2298804 and the incidence of lupus nephritis, rs2298804 seemed to protect against proteinunia, fever and hypocomplementaemia in patients with SLE, but appeared to be a risk factor for photosensitivity and vasculitis.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Alleles. Asian Continental Ancestry Group / genetics. Case-Control Studies. Child. Child, Preschool. China. Female. Gene Frequency. Genetic Predisposition to Disease / genetics. Genotype. Humans. Infant. Male. Middle Aged. Regression Analysis. Sex Factors. Young Adult

  • Genetic Alliance. consumer health - Lupus.
  • Genetic Alliance. consumer health - Systemic lupus erythematosus.
  • MedlinePlus Health Information. consumer health - Lupus.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © The Author(s) CED © 2013 British Association of Dermatologists.
  • (PMID = 23621092.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / FCER1A protein, human; 0 / Receptors, IgE
  •  go-up   go-down


23. Pérez-Miranda AM, Alfonso-Sánchez MA, Peña JA, Calderón R: HLA-DQA1 polymorphism in autochthonous Basques from Navarre (Spain): genetic position within European and Mediterranean scopes. Tissue Antigens; 2003 Jun;61(6):465-74
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this work, a sample of 112 individuals from an autochthonous Basque population (Northern Navarre, Spain) were typed at the DNA level for the HLA-DQA1 locus, with the aim of characterizing its polymorphism and analyzing the genetic relationships of Basque Navarrese with other Caucasian populations.
  • In Navarrese population, the most frequent alleles were DQA1*01 (0.375) and DQA1*02 (0.259).
  • Frequency clines for both DQA1*0103 allele and DQA1*04* allele cluster (including DQA1*0401, DQA1*0501 and DQA1*0601) among the European and Mediterranean populations considered are reported for the first time.
  • The analysis of genetic relationships among populations showed a high genetic affinity between the Basque subpopulations of Northern Navarre and Guipúzcoa, which in turn tended to plot separately from the remaining European and Mediterranean populations.
  • In the same way, the Basques showed no clear relationship to North African populations, as postulated in several previous HLA studies.
  • These two subpopulations seem to show low levels of admixture with other non-Basque neighboring populations, probably because of their deeply rooted ethnicity and the existence of a linguistic barrier to random mating.
  • [MeSH-major] Ethnic Groups / genetics. European Continental Ancestry Group / genetics. HLA-DQ Antigens / genetics. Polymorphism, Genetic
  • [MeSH-minor] DNA / genetics. DNA Primers. Gene Amplification. Gene Frequency. Genetic Heterogeneity. Genetic Variation. Genetics, Population. HLA-DQ alpha-Chains. Histocompatibility Testing. Humans. Mediterranean Sea. Polymerase Chain Reaction. Spain

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12823770.001).
  • [ISSN] 0001-2815
  • [Journal-full-title] Tissue antigens
  • [ISO-abbreviation] Tissue Antigens
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA Primers; 0 / HLA-DQ Antigens; 0 / HLA-DQ alpha-Chains; 0 / HLA-DQA1 antigen; 9007-49-2 / DNA
  •  go-up   go-down


24. Zheng X, Duan W, Xu J, Nie C, Yang Z, Wang H, Wang W, Lu D: Functionally significant nicotine acetylcholine receptor subunit α5 promoter haplotypes are associated with susceptibility to lung cancer in Chinese. Cancer; 2011 Oct 15;117(20):4714-23
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Although recent genome-wide association studies have been conducted to reveal the relation between variations in the α5 nicotinic receptor subunit and lung cancer in European and American populations, to the authors' knowledge, no definite information on the role of nicotine acetylcholine receptor subunit α5 (CHRNA5) in lung cancer risk has been obtained in a Chinese population.
  • METHODS: To test this possible association, a case-control study was conducted in 505 patients with lung cancer (cases) and a control group of 498 cancer-free individuals.
  • Surface plasmon resonance demonstrated that both minor alleles (T and del) decreased DNA binding affinity to nuclear extracts, which the authors presumed was responsible for the disparity in promoter activity.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Lung Neoplasms / genetics. Nerve Tissue Proteins / genetics. Polymorphism, Single Nucleotide. Promoter Regions, Genetic / genetics. Receptors, Nicotinic / genetics

  • Genetic Alliance. consumer health - Lung Cancer.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2011 American Cancer Society.
  • (PMID = 21448929.001).
  • [ISSN] 1097-0142
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CHRNA5 protein, human; 0 / Nerve Tissue Proteins; 0 / Receptors, Nicotinic; 8J337D1HZY / Cytosine; QR26YLT7LT / Thymine
  •  go-up   go-down


25. Fey MF, Wainscoat JS, Mukwala EC, Falusi AG, Vulliamy TJ, Luzzatto L: A PvuII restriction fragment length polymorphism of the glucose-6-phosphate dehydrogenase gene is an African-specific marker. Hum Genet; 1990 Apr;84(5):471-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A population survey shows this RFLP to be specific for African populations, with frequencies of the rarer allele (PvuII type 2 site present) of 0.32-0.40 in Kenyans, Nigerians, Zambians, and West Indians.
  • This allele has not been found in the European, Asian and Middle Eastern populations studied.
  • Such population-specific markers may be useful in the study of population affinities and may provide insight into prehistoric migrations of peoples.
  • [MeSH-major] African Continental Ancestry Group / genetics. Deoxyribonucleases, Type II Site-Specific. Genetic Markers. Glucosephosphate Dehydrogenase / genetics. Polymorphism, Restriction Fragment Length
  • [MeSH-minor] Female. Gene Frequency. Genetics, Population. Humans. Male. Pedigree

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 1988 May;42(5):735-41 [2895981.001]
  • [Cites] Adv Hum Genet. 1985;14:217-329, 386-8 [3887862.001]
  • [Cites] Proc Natl Acad Sci U S A. 1988 Jul;85(14):5171-5 [3393536.001]
  • [Cites] Am J Hum Genet. 1988 Jun;42(6):872-6 [2897162.001]
  • [Cites] Nucleic Acids Res. 1986 Mar 25;14(6):2511-22 [3515319.001]
  • [Cites] Nature. 1986 Feb 6-12;319(6053):491-3 [3003580.001]
  • (PMID = 1969844.001).
  • [ISSN] 0340-6717
  • [Journal-full-title] Human genetics
  • [ISO-abbreviation] Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Genetic Markers; EC 1.1.1.49 / Glucosephosphate Dehydrogenase; EC 3.1.21.4 / CAGCTG-specific type II deoxyribonucleases; EC 3.1.21.4 / Deoxyribonucleases, Type II Site-Specific
  •  go-up   go-down


26. Bussaratid V, Walsh DS, Wilairatana P, Krudsood S, Silachamroon U, Looareesuwan S: Frequency of pruritus in Plasmodium vivax malaria patients treated with chloroquine in Thailand. Trop Doct; 2000 Oct;30(4):211-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chloroquine-induced itch in black-skinned African malaria patients is common and frequently leads to poor compliance or treatment defaulting.To assess the frequency and severity of chloroquine-induced pruritus in an Asian population, we reviewed case records of 1189 Plasmodium vivax malaria patients treated with chloroquine (25 mg/kg over 3 days) at the Bangkok Hospital for Tropical Diseases from 1992 through 1997.
  • The pruritus did not interfere with daily activity, was reduced in intensity by anti-histamine therapy, and did not affect the patient's willingness to complete the chloroquine regimen.
  • Our findings indicate that the frequency of chloroquine-induced pruritus in Asian patients treated with chloroquine for P. vivax malaria is low in comparison with black-skinned Africans.This may be related to pharmacogenetic factors, the infective Plasmodium species, drug metabolism or drug-parasite interactions, or a lower affinity of chloroquine for less pigmented skin.
  • [MeSH-major] Antimalarials / adverse effects. Asian Continental Ancestry Group. Chloroquine / adverse effects. Drug Eruptions / epidemiology. Malaria, Vivax / drug therapy. Pruritus / epidemiology

  • Genetic Alliance. consumer health - Malaria.
  • MedlinePlus Health Information. consumer health - Itching.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CHLOROQUINE .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11075653.001).
  • [ISSN] 0049-4755
  • [Journal-full-title] Tropical doctor
  • [ISO-abbreviation] Trop Doct
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimalarials; 886U3H6UFF / Chloroquine
  •  go-up   go-down


27. Chaubey G, Endicott P: The Andaman Islanders in a regional genetic context: reexamining the evidence for an early peopling of the archipelago from South Asia. Hum Biol; 2013 Feb-Jun;85(1-3):153-72
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Despite over 150 years of research and study, questions over the extent of shared ancestry between Andaman Islanders and other small-bodied, gracile, dark-skinned populations throughout the region are still unresolved.
  • Recent population genetic studies have tended to emphasize long-term physical isolation of the Andaman Islanders and an affinity to ancestral populations of South Asia.
  • We reexamine the genetic evidence from genome-wide autosomal single-nucleotide polymorphism (SNP) data for a shared history between the tribes of Little Andaman (Onge) and Great Andaman, and between these two groups and the rest of South and Southeast Asia (both negrito and non-negrito groups).
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Genetics, Population

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2013 Wayne State University Press, Detroit, Michigan 48201-1309.
  • (PMID = 24297224.001).
  • [ISSN] 1534-6617
  • [Journal-full-title] Human biology
  • [ISO-abbreviation] Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


28. Nurse GT, Dunn DS, Rootman AJ, Jenkins T: Sero-genetic studies on the Ambo of Namibia. Gene Geogr; 1987 Aug;1(2):65-79
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Ambo are the largest population group of Namibia/South West Africa and consist of seven geographical and sociopolitical entities speaking different dialects of a common language.
  • Nearly 600 individuals representing all the dialect groups were tested for 23 sero-genetic systems: the results reveal no evidence of significant San admixture and unusual alleles suggest an affinity with the Herero which confirms oral traditions of a common origin.
  • [MeSH-major] Blood Group Antigens / genetics. Erythrocytes / enzymology. Gene Frequency. Hemoglobins / genetics. Transferrin / genetics
  • [MeSH-minor] African Continental Ancestry Group / genetics. Enzymes / genetics. Haptoglobins / genetics. Humans. Male. Namibia. Phenotype. Transients and Migrants

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 3154116.001).
  • [ISSN] 0394-249X
  • [Journal-full-title] Gene geography : a computerized bulletin on human gene frequencies
  • [ISO-abbreviation] Gene Geogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ITALY
  • [Chemical-registry-number] 0 / Blood Group Antigens; 0 / Enzymes; 0 / Haptoglobins; 0 / Hemoglobins; 0 / Transferrin
  •  go-up   go-down


29. Ossenberg NS: Within and between race distances in population studies based on discrete traits of the human skull. Am J Phys Anthropol; 1976 Nov;45(3 pt. 2):701-15
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Within and between race distances in population studies based on discrete traits of the human skull.
  • A battery of 24 discrete cranial traits has been tested for its power to discriminate within- and between-race distances for the two principal North American indigenous populations: Indian (7 samples, N = 366) and Eskimo (7 samples, N = 451).
  • Separate male-female analysis of the three largest samples indicates that distances for pooled samples are not seriously affected by the sex component.
  • This battery of features yields valid taxonomical information useful in conjunction with other physical data to reconstruct affinities of extinct populations.
  • [MeSH-major] African Continental Ancestry Group. Genetics, Population. Indians, North American. Inuits. Skull / anatomy & histology

  • MedlinePlus Health Information. consumer health - Native American Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 998761.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  •  go-up   go-down


30. Nishimoto K, Ikari K, Kaneko H, Tsukahara S, Kochi Y, Yamamoto K, Nakamura Y, Toyama Y, Taniguchi A, Yamanaka H, Momohara S: Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population. J Rheumatol; 2011 Feb;38(2):221-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
  • While the subsequent replication study did not initially confirm the observed significant association (OR 1.13, p = 0.062), an in-depth stratified analysis revealed significant association in patients testing positive to anti-cyclic citrullinated peptide (anti-CCP) antibody in the replication data set (OR 1.15, p = 0.044).
  • The allele associated with RA susceptibility had a higher binding affinity for HEK298-derived nuclear factors compared to the nonsusceptible allelic variant of rs3775369.
  • CONCLUSION: A significant association between EMCN and RA susceptibility was detected in our Japanese study population.
  • [MeSH-minor] Adult. Alleles. Asian Continental Ancestry Group / genetics. Electrophoretic Mobility Shift Assay. Enzyme-Linked Immunosorbent Assay. Female. Gene Frequency. Genetic Association Studies. Genetic Predisposition to Disease. Genotype. Haplotypes. Humans. Immunohistochemistry. Male. Middle Aged. Odds Ratio. Polymorphism, Single Nucleotide

  • Genetic Alliance. consumer health - Arthritis.
  • Genetic Alliance. consumer health - Rheumatoid arthritis.
  • MedlinePlus Health Information. consumer health - Rheumatoid Arthritis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21159824.001).
  • [ISSN] 0315-162X
  • [Journal-full-title] The Journal of rheumatology
  • [ISO-abbreviation] J. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / EMCN protein, human; 0 / Sialoglycoproteins
  •  go-up   go-down


31. Martiniano R, Caffell A, Holst M, Hunter-Mann K, Montgomery J, Müldner G, McLaughlin RL, Teasdale MD, van Rheenen W, Veldink JH, van den Berg LH, Hardiman O, Carroll M, Roskams S, Oxley J, Morgan C, Thomas MG, Barnes I, McDonnell C, Collins MJ, Bradley DG: Genomic signals of migration and continuity in Britain before the Anglo-Saxons. Nat Commun; 2016 Jan 19;7:10326
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, this has not benefited from direct analyses of ancient genomes.
  • Six of the Roman genomes show affinity with modern British Celtic populations, particularly Welsh, but significantly diverge from populations from Yorkshire and other eastern English samples.
  • They also show similarity with the earlier Iron-Age genome, suggesting population continuity, but differ from the later Anglo-Saxon genome.
  • Strikingly, one Roman skeleton shows a clear signal of exogenous origin, with affinities pointing towards the Middle East, confirming the cosmopolitan character of the Empire, even at its northernmost fringes.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Bioinformatics. 2009 Jul 15;25(14):1754-60 [19451168.001]
  • [Cites] Am J Hum Genet. 2007 Nov;81(5):1084-97 [17924348.001]
  • [Cites] Nature. 2015 Mar 19;519(7543):309-14 [25788095.001]
  • [Cites] BMC Bioinformatics. 2014;15:356 [25420514.001]
  • [Cites] Bioinformatics. 2009 Aug 15;25(16):2078-9 [19505943.001]
  • [Cites] Genome Res. 2009 Sep;19(9):1655-64 [19648217.001]
  • [Cites] Nat Genet. 2009 Oct;41(10):1083-7 [19734901.001]
  • [Cites] Cold Spring Harb Protoc. 2010 Jun;2010(6):pdb.prot5448 [20516186.001]
  • [Cites] Genome Res. 2010 Sep;20(9):1297-303 [20644199.001]
  • [Cites] Eur J Hum Genet. 2011 Jan;19(1):95-101 [20736979.001]
  • [Cites] Ann Hum Genet. 2008 May;72(Pt 3):337-48 [18294359.001]
  • [Cites] Neurobiol Aging. 2015 Feb;36(2):1221.e7-13 [25442119.001]
  • [Cites] Cancer Sci. 2011 May;102(5):1076-80 [21306478.001]
  • [Cites] Nat Methods. 2012 Feb;9(2):179-81 [22138821.001]
  • [Cites] PLoS Genet. 2012 Jan;8(1):e1002453 [22291602.001]
  • [Cites] Science. 2012 Apr 27;336(6080):466-9 [22539720.001]
  • [Cites] J Thromb Haemost. 2012 Aug;10(8):1521-31 [22672568.001]
  • [Cites] Nature. 2012 Nov 1;491(7422):56-65 [23128226.001]
  • [Cites] Forensic Sci Int Genet. 2013 Jan;7(1):98-115 [22917817.001]
  • [Cites] PLoS Genet. 2013 Mar;9(3):e1003372 [23555287.001]
  • [Cites] Bioinformatics. 2013 Jul 1;29(13):1682-4 [23613487.001]
  • [Cites] Hum Mutat. 2013 Sep;34(9):1189-94 [23696374.001]
  • [Cites] Genetics. 2013 Nov;195(3):693-702 [24026093.001]
  • [Cites] G3 (Bethesda). 2013 Nov;3(11):2059-67 [24048645.001]
  • [Cites] Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2229-34 [24469802.001]
  • [Cites] Science. 2014 Feb 14;343(6172):747-51 [24531965.001]
  • [Cites] Nat Genet. 2014 Apr;46(4):409-15 [24633160.001]
  • [Cites] Sci Rep. 2014;4:5994 [25104065.001]
  • [Cites] Nat Commun. 2014;5:5257 [25334030.001]
  • [Cites] Hum Mutat. 2015 Jan;36(1):151-9 [25338970.001]
  • [Cites] Nat Genet. 2002 Feb;30(2):233-7 [11788828.001]
  • [Cites] Mol Biol Evol. 2002 Jul;19(7):1008-21 [12082121.001]
  • [Cites] Curr Biol. 2003 May 27;13(11):979-84 [12781138.001]
  • [Cites] Am J Hum Genet. 2004 May;74(5):1023-34 [15069642.001]
  • [Cites] Am J Hum Genet. 2004 Jun;74(6):1111-20 [15114531.001]
  • [Cites] Am J Phys Anthropol. 1998 Apr;105(4):539-43 [9584894.001]
  • [Cites] Nat Genet. 1999 Oct;23(2):147 [10508508.001]
  • [Cites] Mol Biol Evol. 2006 Jan;23(1):152-61 [16151183.001]
  • [Cites] Am J Hum Genet. 2006 Feb;78(2):334-8 [16358217.001]
  • [Cites] Forensic Sci Int. 2006 Jul 13;160(2-3):207-16 [16289900.001]
  • [Cites] Proc Biol Sci. 2006 Oct 22;273(1601):2651-7 [17002951.001]
  • [Cites] Nature. 2007 Jun 7;447(7145):661-78 [17554300.001]
  • [Cites] PLoS Genet. 2006 Dec;2(12):e190 [17194218.001]
  • [Cites] Hum Mutat. 2009 Feb;30(2):E386-94 [18853457.001]
  • (PMID = 26783717.001).
  • [ISSN] 2041-1723
  • [Journal-full-title] Nature communications
  • [ISO-abbreviation] Nat Commun
  • [Language] ENG
  • [Grant] United Kingdom / Wellcome Trust / / 076113
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4735653
  •  go-up   go-down


32. Tömöry G, Csányi B, Bogácsi-Szabó E, Kalmár T, Czibula A, Csosz A, Priskin K, Mende B, Langó P, Downes CS, Raskó I: Comparison of maternal lineage and biogeographic analyses of ancient and modern Hungarian populations. Am J Phys Anthropol; 2007 Nov;134(3):354-68
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of maternal lineage and biogeographic analyses of ancient and modern Hungarian populations.
  • In order to study the continuity in maternal lineage between ancient and modern Hungarian populations, polymorphisms in the HVSI and protein coding regions of mitochondrial DNA sequences of 27 ancient samples (10th-11th centuries), 101 modern Hungarian, and 76 modern Hungarian-speaking Sekler samples from Transylvania were analyzed.
  • The data were compared with sequences derived from 57 European and Asian populations, including Finno-Ugric populations, and statistical analyses were performed to investigate their genetic relationships.
  • Only 2 of 27 ancient Hungarian samples are unambiguously Asian: the rest belong to one of the western Eurasian haplogroups, but some Asian affinities, and the genetic effect of populations who came into contact with ancient Hungarians during their migrations are seen.
  • Commoners show a predominance of mtDNA haplotypes and haplogroups (H, R, T), common in west Eurasia, while high-status individuals, presumably conquering Hungarians, show a more heterogeneous haplogroup distribution, with haplogroups (N1a, X) which are present at very low frequencies in modern worldwide populations and are absent in recent Hungarian and Sekler populations.
  • Modern Hungarian-speaking populations seem to be specifically European.
  • Our findings demonstrate that significant genetic differences exist between the ancient and recent Hungarian-speaking populations, and no genetic continuity is seen.
  • [MeSH-major] European Continental Ancestry Group / history. Hair / chemistry
  • [MeSH-minor] Base Sequence. DNA / analysis. DNA / history. DNA Primers. DNA, Mitochondrial / analysis. Female. Femur / chemistry. Fossils. Genetics, Population. Haplotypes / genetics. History, 21st Century. History, Ancient. History, Medieval. Humans. Hungary. Molecular Sequence Data. Mothers. Pedigree. Polymerase Chain Reaction

  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17632797.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AF487494/ AF487556/ AF487557/ AF487558/ AF487559/ AF487561/ AF487562/ AF487563/ AF487564/ AF487565/ AF487566/ AF487567/ AF487568/ AF487569/ AF487570/ AF487574/ AF487575/ AF487576/ AF487580/ AF487583/ AF487586/ AF487590/ AF487596/ AF487598/ AF487599/ AF487600/ AF487602/ AF487604/ AF487612/ AF487613/ AF487614/ DQ246265/ DQ246266/ DQ246267/ DQ246268/ DQ246269/ DQ246270/ DQ246271/ DQ246272/ DQ246273/ DQ246274/ DQ246275/ DQ246276/ DQ246277/ DQ246278/ DQ246279/ DQ246280/ DQ246281/ DQ246282/ DQ246283/ DQ246284/ DQ246285/ DQ246286/ DQ246287/ DQ246288/ DQ246289/ DQ246290/ DQ246291/ DQ246292/ DQ246293/ DQ246294/ DQ246295/ DQ246296/ DQ246297/ DQ246298/ DQ246299/ DQ246300/ DQ246301/ DQ246302/ DQ246303/ DQ246304/ DQ246305/ DQ246306/ DQ246307/ DQ246308/ DQ246309/ DQ246310/ DQ246311/ DQ246312/ DQ246313/ DQ246314/ DQ246315/ DQ246316/ DQ246317/ DQ246318/ DQ246319/ DQ246320/ DQ246321/ DQ246322/ DQ246323/ DQ246324/ DQ246325/ DQ246326/ DQ246327/ DQ246328/ DQ246329/ DQ246330/ DQ246331/ DQ246332/ DQ246333/ DQ246334/ DQ246335/ DQ246336/ DQ246337/ DQ246338/ DQ246339/ DQ246340/ DQ246341/ DQ246342/ DQ246343/ DQ246344/ DQ246345/ DQ246346/ DQ246347/ DQ246348/ DQ246349/ DQ246350/ DQ246351/ DQ246352/ DQ246353/ DQ246354/ DQ246355/ DQ246356/ DQ246357/ DQ246358/ DQ246359/ DQ246360/ DQ246361/ DQ246362/ DQ246363/ DQ246364/ DQ246365/ DQ246366/ DQ246367/ DQ246368/ DQ246369/ DQ246370/ DQ246371/ DQ246372/ DQ246373/ DQ246374/ DQ246375/ DQ246376/ DQ246377/ DQ246378/ DQ246379/ DQ246380/ DQ246381/ DQ246382/ DQ246383/ DQ246384/ DQ246385/ DQ246386/ DQ246387/ DQ246388/ DQ246389/ DQ246390/ DQ246391/ DQ246392/ DQ246393/ DQ246394/ DQ246395/ DQ246396/ DQ246397/ DQ246398/ DQ246399/ DQ246400/ DQ246401/ DQ246402/ DQ246403/ DQ246404/ DQ246405/ DQ246406/ DQ246407/ DQ246408/ DQ246409/ DQ246410/ DQ246411/ DQ246412/ DQ246413/ DQ246414/ DQ246415/ DQ246416/ DQ246417/ DQ246418/ DQ246419/ DQ246420/ DQ246421/ DQ246422/ DQ246423/ DQ246424/ DQ246425/ DQ246426/ DQ246427/ DQ246428/ DQ246429/ DQ246430/ DQ246431/ DQ246432/ DQ246433/ DQ246434/ DQ246435/ DQ246436/ DQ246437
  • [Publication-type] Comparative Study; Historical Article; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Mitochondrial; 9007-49-2 / DNA
  •  go-up   go-down


33. Yao YG, Kong QP, Man XY, Bandelt HJ, Zhang YP: Reconstructing the evolutionary history of China: a caveat about inferences drawn from ancient DNA. Mol Biol Evol; 2003 Feb;20(2):214-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Further typing for mtDNA haplogroup-diagnostic coding region polymorphisms, however, is indispensable for establishing the geographic/genetic affinities of ancient samples with less ambiguity.
  • The reanalysis of two previously published ancient mtDNA population data sets from Linzi (same province) then indicates that the ancient populations had features in common with the modern populations from south China rather than any specific affinity to the European mtDNA pool.
  • Our results highlight that ancient mtDNA data obtained under different sampling schemes and subject to potential contamination can easily create the impression of drastic spatiotemporal changes in the genetic structure of a regional population during the past few thousand years if inappropriate methods of data analysis are employed.
  • [MeSH-minor] Asian Continental Ancestry Group. China. Evolution, Molecular. Gene Frequency. Genetic Variation. Genetics, Population. Haplotypes. Humans. Paleontology. Polymorphism, Genetic. Principal Component Analysis

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12598688.001).
  • [ISSN] 0737-4038
  • [Journal-full-title] Molecular biology and evolution
  • [ISO-abbreviation] Mol. Biol. Evol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


34. Zhuang Y, Xu Z, de Vries DE, Wang Q, Shishido A, Comisar C, Ford JA, Keen M, Achira M, Tsukamoto Y, Petty KJ, Davis HM, Zhou H: Pharmacokinetics and safety of sirukumab following a single subcutaneous administration to healthy Japanese and Caucasian subjects. Int J Clin Pharmacol Ther; 2013 Mar;51(3):187-99
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Sirukumab (CNTO 136) is a human mAb with high affinity and specificity for binding to interleukin-6.
  • Noncompartmental analysis and population pharmacokinetic modeling were conducted to characterize sirukumab pharmacokinetics.
  • A one-compartment population pharmacokinetic model adequately described sirukumab pharmacokinetics following s.c. administration.
  • The estimated population means for CL/F, V/F, and Ka were 0.54 ±0.03 l/day, 12.2 ±0.55 l, and 0.77 ±0.07 day-1, respectively.
  • Race was not a significant covariate on CL/F or V/F.
  • Adverse events were generally mild and did not appear to be dose-related or lead to study discontinuation.
  • [MeSH-minor] Adolescent. Adult. Asian Continental Ancestry Group. European Continental Ancestry Group. Humans. Injections, Subcutaneous. Male

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 23357841.001).
  • [ISSN] 0946-1965
  • [Journal-full-title] International journal of clinical pharmacology and therapeutics
  • [ISO-abbreviation] Int J Clin Pharmacol Ther
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Interleukin-6; 0 / sirukumab
  •  go-up   go-down


35. Gené M, Moreno P, Borrego N, Piqué E, Brandt C, Mas J, Luna M, Corbella J, Huguet E: The Bubi population of Equatorial Guinea characterised by HUMTH01, HUMVWA31A, HUMCSF1PO, HUMTPOX, D3S1358, D8S1179, D18S51 and D19S253 STR polymorphisms. Int J Legal Med; 2001;114(4-5):298-300
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The Bubi population of Equatorial Guinea characterised by HUMTH01, HUMVWA31A, HUMCSF1PO, HUMTPOX, D3S1358, D8S1179, D18S51 and D19S253 STR polymorphisms.
  • Allele frequencies for eight STR loci (HUMTH01, HUMVWA31A, HUMCSF1PO, HUMTPOX, D3S1358, D8S1179, D18S51, D19S253) have been analysed in the Bubi population of Bioko Island, Equatorial Guinea.
  • Data obtained were compared with that of Caucasian and African populations.
  • Significant differences were found for all systems between all the black populations compared and the Caucasoid population.
  • Similarities were observed between the Bubi and Zimbabweans, and also with African American populations.
  • Also, more affinities were observed between Zimbabweans and Ugandans and Ovambos than between these groups and the Bubi population.
  • [MeSH-minor] African Continental Ancestry Group / genetics. Equatorial Guinea. Gene Frequency. Genetic Heterogeneity. Genotype. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11355417.001).
  • [ISSN] 0937-9827
  • [Journal-full-title] International journal of legal medicine
  • [ISO-abbreviation] Int. J. Legal Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


36. Krithika S, Maji S, Vasulu TS: A microsatellite guided insight into the genetic status of adi, an isolated hunting-gathering tribe of northeast India. PLoS One; 2008;3(7):e2549
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tibeto-Burman populations of India provide an insight into the peopling of India and aid in understanding their genetic relationship with populations of East, South and Southeast Asia.
  • The study investigates the genetic status of one such Tibeto-Burman group, Adi of Arunachal Pradesh based on 15 autosomal microsatellite markers.
  • Further the study examines, based on 9 common microsatellite loci, the genetic relationship of Adi with 16 other Tibeto-Burman speakers of India and 28 neighboring populations of East and Southeast Asia.
  • Overall, the results support the recent formation of the Adi sub-tribes from a putative ancestral group and reveal that geographic contiguity is a major influencing factor of the genetic affinity among the Tibeto-Burman populations of India.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Microsatellite Repeats
  • [MeSH-minor] DNA Fingerprinting. Genetic Variation. Genetics, Population. Humans. India / ethnology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Forensic Sci Int. 2007 May 24;168(2-3):236-40 [16542804.001]
  • [Cites] Forensic Sci Int. 2005 Sep 10;152(2-3):263-5 [15978354.001]
  • [Cites] Forensic Sci Int. 2007 Jul 4;169(2-3):239-43 [16621380.001]
  • [Cites] Forensic Sci Int. 2005 Sep 10;152(2-3):281-4 [15978356.001]
  • [Cites] Leg Med (Tokyo). 2005 Oct;7(5):306-10 [16046272.001]
  • [Cites] Forensic Sci Int. 2005 Nov 10;154(1):78-80 [16182951.001]
  • [Cites] J Forensic Sci. 2005 Sep;50(5):1225-8 [16225237.001]
  • [Cites] Forensic Sci Int. 2005 Dec 20;155(2-3):219-21 [15946815.001]
  • [Cites] J Forensic Sci. 2006 Jan;51(1):188-9 [16423249.001]
  • [Cites] Ann Hum Biol. 2006 Jan-Feb;33(1):26-42 [16500809.001]
  • [Cites] Forensic Sci Int. 2006 May 10;158(2-3):234-7 [16002249.001]
  • [Cites] Hum Biol. 2006 Apr;78(2):221-7 [17036928.001]
  • [Cites] Leg Med (Tokyo). 2007 Jan;9(1):30-2 [17150403.001]
  • [Cites] J Forensic Sci. 2007 Jan;52(1):239-41 [17209951.001]
  • [Cites] Forensic Sci Int. 2007 May 24;168(2-3):227-31 [16540274.001]
  • [Cites] Forensic Sci Int. 2007 Jul 4;169(2-3):234-8 [16621386.001]
  • [Cites] Forensic Sci Int. 2007 Jul 4;169(2-3):266-73 [16684594.001]
  • [Cites] Leg Med (Tokyo). 2007 Jul;9(4):210-7 [17306594.001]
  • [Cites] Forensic Sci Int. 2007 Jul 20;170(1):68-72 [16730150.001]
  • [Cites] Forensic Sci Int. 2007 Sep 13;171(2-3):222-5 [16806770.001]
  • [Cites] Hum Biol. 2007 Jun;79(3):321-37 [18078205.001]
  • [Cites] Hum Biol. 2007 Jun;79(3):355-62 [18078207.001]
  • [Cites] Genetics. 2000 Jun;155(2):945-59 [10835412.001]
  • [Cites] J Forensic Sci. 2001 Jan;46(1):184-8 [11210912.001]
  • [Cites] Hum Biol. 2002 Feb;74(1):33-49 [11931578.001]
  • [Cites] Forensic Sci Int. 2002 Jun 25;127(1-2):150-5 [12173571.001]
  • [Cites] J Forensic Sci. 2002 Sep;47(5):1163-7 [12353571.001]
  • [Cites] Int J Legal Med. 2002 Aug;116(4):246-8 [12420705.001]
  • [Cites] Ann Hum Genet. 2002 Nov;66(Pt 5-6):361-8 [12516613.001]
  • [Cites] Eur J Hum Genet. 2003 Mar;11(3):253-64 [12678055.001]
  • [Cites] Forensic Sci Int. 2003 Apr 8;132(3):216-22 [12711207.001]
  • [Cites] Forensic Sci Int. 2003 Sep 9;136(1-3):92-5 [12969628.001]
  • [Cites] Forensic Sci Int. 2003 Dec 17;138(1-3):119-22 [14642730.001]
  • [Cites] Forensic Sci Int. 2004 May 10;141(2-3):175-83 [15062959.001]
  • [Cites] Am J Hum Biol. 2004 May-Jun;16(3):311-27 [15101056.001]
  • [Cites] Am J Hum Biol. 2004 May-Jun;16(3):334-45 [15101058.001]
  • [Cites] Mol Biol Evol. 2004 Aug;21(8):1525-33 [15128876.001]
  • [Cites] Brief Bioinform. 2004 Jun;5(2):150-63 [15260895.001]
  • [Cites] Proc Natl Acad Sci U S A. 1973 Dec;70(12):3321-3 [4519626.001]
  • [Cites] J Mol Evol. 1983;19(2):153-70 [6571220.001]
  • [Cites] Hum Hered. 1986;36(6):388-96 [3793118.001]
  • [Cites] Hum Hered. 1988;38(5):261-6 [3235091.001]
  • [Cites] Biometrics. 1992 Jun;48(2):361-72 [1637966.001]
  • [Cites] Ann Hum Biol. 1992 Sep-Oct;19(5):489-501 [1510344.001]
  • [Cites] Hum Hered. 1994 Jan-Feb;44(1):1-9 [8163285.001]
  • [Cites] Genetics. 1996 Sep;144(1):389-99 [8878702.001]
  • [Cites] Forensic Sci Int. 2005 Jan 6;147(1):89-91 [15541596.001]
  • [Cites] Hum Biol. 2004 Aug;76(4):569-90 [15754973.001]
  • [Cites] Forensic Sci Int. 2005 Jul 16;151(2-3):293-7 [15939165.001]
  • [Cites] Leg Med (Tokyo). 2005 Jul;7(4):222-6 [15951216.001]
  • [Cites] Forensic Sci Int. 2007 Jun 14;169(1):e3-6 [17350778.001]
  • (PMID = 18596928.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2435608
  •  go-up   go-down


37. Passarino G, Semino O, Quintana-Murci L, Excoffier L, Hammer M, Santachiara-Benerecetti AS: Different genetic components in the Ethiopian population, identified by mtDNA and Y-chromosome polymorphisms. Am J Hum Genet; 1998 Feb;62(2):420-34
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Different genetic components in the Ethiopian population, identified by mtDNA and Y-chromosome polymorphisms.
  • Seventy-seven Ethiopians were investigated for mtDNA and Y chromosome-specific variations, in order to (1) define the different maternal and paternal components of the Ethiopian gene pool, (2) infer the origins of these maternal and paternal lineages and estimate their relative contributions, and (3) obtain information about ancient populations living in Ethiopia.
  • Results from these markers led to the hypothesis that the Ethiopian population (1) experienced Caucasoid gene flow mainly through males, (2) contains African components ascribable to Bantu migrations and to an in situ differentiation process from an ancestral African gene pool, and (3) exhibits some Y-chromosome affinities with the Tsumkwe San (a very ancient African group).
  • [MeSH-major] African Continental Ancestry Group / genetics. DNA, Mitochondrial / genetics. Ethnic Groups / genetics. Polymorphism, Genetic. Y Chromosome
  • [MeSH-minor] Chromosome Mapping. Emigration and Immigration. Enzymes / genetics. Ethiopia. European Continental Ancestry Group / genetics. Gene Pool. Genetic Markers. Geography. Haplotypes. Humans. Male. Phylogeny. Polymorphism, Restriction Fragment Length

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 1994 Feb;54(2):303-18 [8304347.001]
  • [Cites] Am J Hum Genet. 1997 Nov;61(5):1015-35 [9346874.001]
  • [Cites] J Mol Evol. 1993 Oct;37(4):435-40 [8308911.001]
  • [Cites] Am J Phys Anthropol. 1994 Feb;93(2):189-99 [8147435.001]
  • [Cites] Hum Biol. 1994 Feb;66(1):1-12 [7908889.001]
  • [Cites] Hum Biol. 1994 Aug;66(4):601-11 [7916320.001]
  • [Cites] Am J Hum Genet. 1994 Oct;55(4):760-76 [7942855.001]
  • [Cites] Mol Biol Evol. 1994 Sep;11(5):749-61 [7968488.001]
  • [Cites] Hum Mol Genet. 1994 Dec;3(12):2159-61 [7881413.001]
  • [Cites] Mol Biol Evol. 1995 Mar;12(2):334-45 [7700157.001]
  • [Cites] Am J Hum Genet. 1995 Apr;56(4):951-62 [7717406.001]
  • [Cites] Ann Hum Genet. 1995 Jan;59(Pt 1):43-61 [7762984.001]
  • [Cites] Gene Geogr. 1994 Apr;8(1):45-54 [7619775.001]
  • [Cites] J Mol Evol. 1983;19(3-4):255-71 [6310133.001]
  • [Cites] Science. 1985 Dec 20;230(4732):1403-6 [2999986.001]
  • [Cites] Nature. 1986 Feb 6-12;319(6053):491-3 [3003580.001]
  • [Cites] Am J Hum Genet. 1986 Apr;38(4):407-18 [3010708.001]
  • [Cites] Nature. 1987 Jan 1-7;325(6099):31-6 [3025745.001]
  • [Cites] Am J Hum Genet. 1988 Oct;43(4):534-44 [2902791.001]
  • [Cites] Gene Geogr. 1987 Dec;1(3):201-6 [2908692.001]
  • [Cites] Ann Hum Genet. 1990 Oct;54(Pt 4):287-96 [2285217.001]
  • [Cites] Isr J Med Sci. 1991 May;27(5):245-51 [2050504.001]
  • [Cites] Am J Hum Genet. 1992 Jan;50(1):107-25 [1729883.001]
  • [Cites] Genetics. 1992 Jan;130(1):139-52 [1346259.001]
  • [Cites] Genetics. 1992 Jan;130(1):153-62 [1346260.001]
  • [Cites] Ann Hum Genet. 1992 Oct;56(Pt 4):303-10 [1492745.001]
  • [Cites] Ann Hum Genet. 1992 Oct;56(Pt 4):315-24 [1362872.001]
  • [Cites] Science. 1993 Jan 29;259(5095):639-46 [8430313.001]
  • [Cites] Hum Biol. 1993 Jun;65(3):359-85 [8100548.001]
  • [Cites] Ann Hum Genet. 1993 Jan;57(Pt 1):55-64 [8101437.001]
  • [Cites] Am J Hum Genet. 1993 Sep;53(3):563-90 [7688932.001]
  • [Cites] Am J Hum Genet. 1993 Sep;53(3):591-608 [7688933.001]
  • [Cites] Am J Hum Genet. 1993 Sep;53(3):609-18 [8102506.001]
  • [Cites] Ann Hum Biol. 1993 Sep-Oct;20(5):477-85 [8105748.001]
  • [Cites] Science. 1996 Mar 8;271(5254):1380-7 [8596909.001]
  • [Cites] Am J Hum Genet. 1996 Mar;58(3):595-608 [8644719.001]
  • [Cites] Nat Genet. 1996 Jun;13(2):154-60 [8640220.001]
  • [Cites] Am J Hum Genet. 1996 Aug;59(2):437-44 [8755932.001]
  • [Cites] Ann Hum Biol. 1996 Mar-Apr;23(2):121-6 [8702211.001]
  • [Cites] Am J Hum Genet. 1996 Sep;59(3):741-3 [8751879.001]
  • [Cites] Am J Hum Genet. 1996 Oct;59(4):927-34 [8808610.001]
  • [Cites] Am J Hum Genet. 1996 Oct;59(4):964-8 [8808616.001]
  • [Cites] Am J Hum Genet. 1996 Nov;59(5):1126-33 [8900243.001]
  • [Cites] Hum Biol. 1996 Jun;68(3):467-71 [8935325.001]
  • [Cites] Genetics. 1996 Dec;144(4):1835-50 [8978068.001]
  • [Cites] Am J Hum Genet. 1997 May;60(5):1174-83 [9150165.001]
  • [Cites] Am J Hum Genet. 1994 Feb;54(2):319-30 [8304348.001]
  • (PMID = 9463310.001).
  • [ISSN] 0002-9297
  • [Journal-full-title] American journal of human genetics
  • [ISO-abbreviation] Am. J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / Enzymes; 0 / Genetic Markers
  • [Other-IDs] NLM/ PMC1376879
  •  go-up   go-down


38. Schurr TG, Sukernik RI, Starikovskaya YB, Wallace DC: Mitochondrial DNA variation in Koryaks and Itel'men: population replacement in the Okhotsk Sea-Bering Sea region during the Neolithic. Am J Phys Anthropol; 1999 Jan;108(1):1-39
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitochondrial DNA variation in Koryaks and Itel'men: population replacement in the Okhotsk Sea-Bering Sea region during the Neolithic.
  • In this study, we analyzed the mitochondrial DNA (mtDNA) variation in 202 individuals representing one Itel'men and three Koryak populations from different parts of the Kamchatka peninsula.
  • All mtDNAs were subjected to high resolution restriction (RFLP) analysis and control region (CR) sequencing, and the resulting data were combined with those available for other Siberian and east Asian populations and subjected to statistical and phylogenetic analysis.
  • Together, the Koryaks and Itel'men were found to have mtDNAs belonging to three (A, C, and D) of the four major haplotype groups (haplogroups) observed in Siberian and Native American populations (A-D).
  • While Kamchatka harbored the highest frequencies of haplogroup G mtDNAs, which were widely distributed in eastern Siberian and adjacent east Asian populations, the distribution of haplogroup Y was restricted within a relatively small area and pointed to the lower Amur River-Sakhalin Island region as its place of origin.
  • Furthermore, phylogenetic and statistical analyses showed that Koryaks and Itel'men had stronger genetic affinities with eastern Siberian/east Asian populations than to those of the north Pacific Rim.
  • These results were consistent with colonization events associated with the relatively recent immigration to Kamchatka of new tribes from the Siberian mainland region, although remnants of ancient Beringian populations were still evident in the Koryak and Itel'men gene pools.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. DNA, Mitochondrial / genetics. Genetic Variation. Inuits / genetics. Oceanic Ancestry Group / genetics
  • [MeSH-minor] Alaska. Arctic Regions. Base Sequence. Continental Population Groups. Emigration and Immigration. Haplotypes. Humans. Molecular Sequence Data. Phylogeny. Polymorphism, Restriction Fragment Length. Siberia / ethnology

  • MedlinePlus Health Information. consumer health - Native Hawaiian and Pacific Islander Health.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 9915299.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / GM49615; United States / NHLBI NIH HHS / HL / HL45572; United States / NINDS NIH HHS / NS / NS21328; etc
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


39. Zhou HY, Wang HW, Tan SN, Chen Y, Wang WL, Tao HX, Yin ZC, Zou YH, Ouyang SM, Ni B: Genetic affinities of central China populations. Genet Mol Res; 2014;13(1):616-25
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic affinities of central China populations.
  • By comparison with the surrounding populations, southern China-prevalent haplogroups were detected with relative higher frequency in the Tujia and Miao ethnic populations, such as haplogroup B, with more than 20%, lacking in the Han population, which illustrated its southern origin characters.
  • In addition, we also detected northern of East Asia prevalent haplogroups with a relative higher frequency in Tujia populations than in the Miao and Yao ethnic groups, implying a gene flow from Han populations.
  • Han and ethnic groups in central China exhibited specific ancestors related to their closer language affinity, although there was extensively genetic admixture between Han and ethnic groups.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Chromosomes, Human, Y / genetics. DNA, Mitochondrial / genetics. Genetics, Population

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 24615027.001).
  • [ISSN] 1676-5680
  • [Journal-full-title] Genetics and molecular research : GMR
  • [ISO-abbreviation] Genet. Mol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


40. Zeng Z, Rowold DJ, Garcia-Bertrand R, Calderon S, Regueiro M, Li L, Zhong M, Herrera RJ: Taiwanese aborigines: genetic heterogeneity and paternal contribution to Oceania. Gene; 2014 Jun 1;542(2):240-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We investigate the paternal genetic relationships of these Taiwanese aborigines to 42 Asia-Pacific reference populations, geographically selected to reflect various locations within the Austronesian domain.
  • 1) the Taiwan indigenous populations are highly diverse.
  • In fact, the level of inter-population heterogeneity displayed by the Taiwanese aboriginal populations is close to that exhibited among all 51 Asia-Pacific populations examined;.
  • 2) the asymmetrical contribution of the Taiwanese aborigines to the Oceanic groups.
  • Ami, Bunun and Saisiyat tribes exhibit the strongest paternal links to the Solomon and Polynesian island communities, whereas most of the remaining Taiwanese aboriginal groups are more genetically distant to these Oceanic inhabitants;.
  • 3) the present YSTR analyses does not reveal a strong paternal affinity of the nine Taiwanese tribes to their continental Asian neighbors.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Genetic Variation. Genetics, Population
  • [MeSH-minor] Gene Frequency. Haplotypes. Humans. Male. Oceania. Oceanic Ancestry Group / genetics. Taiwan / ethnology

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2014 Elsevier B.V. All rights reserved.
  • (PMID = 24613753.001).
  • [ISSN] 1879-0038
  • [Journal-full-title] Gene
  • [ISO-abbreviation] Gene
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Austronesian / STR / Taiwan aborigine / Y chromosome
  •  go-up   go-down


41. Tournamille C: [Molecular basis and structure-activity relationships of the Duffy blood group antigens: chemokine and Plasmodium vivax receptors]. Transfus Clin Biol; 2000 Oct;7(5):497-509
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Molecular basis and structure-activity relationships of the Duffy blood group antigens: chemokine and Plasmodium vivax receptors].
  • [Transliterated title] Bases moléculaires et relations structure-fonction des antigènes de groupe sanguin Duffy: récepteur de chimiokines et de Plasmodium vivax.
  • Duffy blood group antigens are of major interest in clinical medicine as they are not only involved in blood transfusion risks and occasionally in neonatal hemolytic disease, but also in the invasion of red blood cells by the hemoparasitic Plasmodium vivax.
  • The Duffy antigens are carried by a 336 amino-acid glycoprotein named the Duffy Antigen/Receptor for Chemokines (DARC) that can bind with high affinity selected members of the CXC and CC classes of chemokines.
  • DARC is not solely expressed in erythroid cells: the same polypeptide isoform is found on the surface of endothelial cells of post-capillary venules throughout the body and also on the surface of Purkinje cells in the cerebellum, although it is encoded by different RNA messengers in each case, i.e., 1.35 and 7.5 kb, respectively.
  • [MeSH-major] Antigens, Protozoan. Carrier Proteins / physiology. Duffy Blood-Group System / physiology. Plasmodium vivax / physiology. Protozoan Proteins. Receptors, Cell Surface / physiology. Receptors, Chemokine / physiology
  • [MeSH-minor] Alleles. Amino Acid Substitution. Animals. Blood Group Incompatibility / etiology. Blood Transfusion. Cells, Cultured. Cercopithecus aethiops. Chemokines, CC / metabolism. Chemokines, CXC / metabolism. Chromosomes, Human, Pair 1 / genetics. Continental Population Groups / genetics. Endothelium, Vascular / metabolism. Erythrocytes / parasitology. Gene Frequency. Genotype. Humans. Models, Molecular. Nerve Tissue Proteins / chemistry. Nerve Tissue Proteins / physiology. Organ Specificity. Phenotype. Polymerase Chain Reaction. Polymorphism, Genetic. Polymorphism, Restriction Fragment Length. Protein Conformation. Protein Structure, Tertiary. Purkinje Cells / metabolism. Recombinant Fusion Proteins / chemistry. Structure-Activity Relationship

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11109635.001).
  • [ISSN] 1246-7820
  • [Journal-full-title] Transfusion clinique et biologique : journal de la Société française de transfusion sanguine
  • [ISO-abbreviation] Transfus Clin Biol
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] FRANCE
  • [Chemical-registry-number] 0 / Antigens, Protozoan; 0 / Carrier Proteins; 0 / Chemokines, CC; 0 / Chemokines, CXC; 0 / DARC protein, human; 0 / Duffy Blood-Group System; 0 / Duffy antigen binding protein, Plasmodium; 0 / Nerve Tissue Proteins; 0 / Protozoan Proteins; 0 / Receptors, Cell Surface; 0 / Receptors, Chemokine; 0 / Recombinant Fusion Proteins
  • [Number-of-references] 59
  •  go-up   go-down


42. Stock JT: The skeletal phenotype of "negritos" from the Andaman Islands and Philippines relative to global variation among hunter-gatherers. Hum Biol; 2013 Feb-Jun;85(1-3):67-94
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The "negrito hypothesis" suggests that populations of small-bodied foragers in South and Southeast Asia who share common phenotypic characteristics may also share a common, ancient origin.
  • The key defining characteristics of the "negrito" phenotype, small body size, dark skin, and tightly curled hair, have been interpreted as linking these populations to sub-Saharan Africans.
  • Current genetic evidence is inconclusive, as it both demonstrates that negrito populations have genetic affinities with neighboring populations but also rare and ancient variation that suggests considerable isolation.
  • Particular emphasis is placed on the comparison of negrito phenotypes to African, Asian, and Australian hunter-gatherer diversity to investigate phenotypic similarities to other populations globally.
  • Although general similarities in size and proportions remain between the Andamanese and Aeta, differences in humero-femoral indices and arm length between these groups and the Efé demonstrate that there is not a generic "pygmy" phenotype.
  • [MeSH-major] Anthropology, Physical. Asian Continental Ancestry Group / genetics. Biological Evolution. Bone and Bones / anatomy & histology. Genetics, Population. Hominidae / genetics
  • [MeSH-minor] Adaptation, Physiological. Animals. Appetitive Behavior. Asia, Southeastern / ethnology. Humans. Phenotype. Philippines / ethnology. Population Dynamics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2013 Wayne State University Press, Detroit, Michigan 48201-1309.
  • (PMID = 24297221.001).
  • [ISSN] 1534-6617
  • [Journal-full-title] Human biology
  • [ISO-abbreviation] Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


43. Antunez-de-Mayolo G, Antunez-de-Mayolo A, Antunez-de-Mayolo P, Papiha SS, Hammer M, Yunis JJ, Yunis EJ, Damodaran C, Martinez de Pancorbo M, Caeiro JL, Puzyrev VP, Herrera RJ: Phylogenetics of worldwide human populations as determined by polymorphic Alu insertions. Electrophoresis; 2002 Sep;23(19):3346-56
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phylogenetics of worldwide human populations as determined by polymorphic Alu insertions.
  • Since some of the insertion alleles have not reached fixation, they remain polymorphic and can be used as biallelic DNA marker systems in investigations of human evolution.
  • The presence of these six PAIs was determined by a polymerase chain reaction (PCR)-based assay in 1646 individuals from 47 populations from around the world.
  • Examination of the populations by plotting the first and second principal components, shows the expected segregation of populations according to geographical vicinity and established ethnic affinities.
  • Centroid analysis demonstrated that sub-Sahara populations have experienced higher than average gene flow and/or represent larger populations as compared to groups in other parts of the globe and especially to known inbreed populations.
  • This is consistent with greater heterogeneity and diversity expected of source groups.
  • In addition, maximum likelihood (ML) analyses were performed with these 47 populations and a hypothetical ancestral group lacking the insertion in all six loci.
  • African populations and admixed groups of African descent formed a single monophyletic group with a basal placement on the tree, which grouped closest to the hypothetical ancestor.
  • [MeSH-minor] Continental Population Groups / genetics. Evolution, Molecular. Genetic Variation / genetics. Humans

  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12373762.001).
  • [ISSN] 0173-0835
  • [Journal-full-title] Electrophoresis
  • [ISO-abbreviation] Electrophoresis
  • [Language] eng
  • [Grant] United States / PHS HHS / / EM 53566-06; United States / NIGMS NIH HHS / GM / S06 GM08205
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Germany
  •  go-up   go-down


44. Chaubey G, Tamang R, Pennarun E, Dubey P, Rai N, Upadhyay RK, Meena RP, Patel JR, van Driem G, Thangaraj K, Metspalu M, Villems R: Reconstructing the population history of the largest tribe of India: the Dravidian speaking Gond. Eur J Hum Genet; 2017 04;25(4):493-498
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reconstructing the population history of the largest tribe of India: the Dravidian speaking Gond.
  • The Gond comprise the largest tribal group of India with a population exceeding 12 million.
  • Therefore, to gain a more comprehensive view on ancient ancestry and genetic affinities of the Gond with the neighbouring populations speaking Indo-European, Dravidian and Austroasiatic languages, we have studied four geographically distinct groups of Gond using high-resolution data.
  • All the Gond groups share a common ancestry with a certain degree of isolation and differentiation.
  • Our allele frequency and haplotype-based analyses reveal that the Gond share substantial genetic ancestry with the Indian Austroasiatic (ie, Munda) groups, rather than with the other Dravidian groups to whom they are most closely related linguistically.
  • [MeSH-major] European Continental Ancestry Group / genetics. Human Migration. Population / genetics

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Eur J Hum Genet. 2017 Nov;25(11):1291 [29023439.001]
  • [Cites] Am J Hum Genet. 2011 Dec 9;89(6):731-44 [22152676.001]
  • [Cites] PLoS Genet. 2006 Dec;2(12):e190 [17194218.001]
  • [Cites] Am J Hum Biol. 2008 Nov-Dec;20(6):683-92 [18464270.001]
  • [Cites] BMC Evol Biol. 2008 Aug 04;8:227 [18680585.001]
  • [Cites] Ann Hum Genet. 2004 Sep;68(Pt 5):453-60 [15469422.001]
  • [Cites] Eur J Hum Genet. 2014 Dec;22(12):1404-12 [24667789.001]
  • [Cites] Mol Biol Evol. 2012 Jan;29(1):359-65 [21917723.001]
  • [Cites] Mol Biol Evol. 2011 Feb;28(2):1013-24 [20978040.001]
  • [Cites] Am J Hum Genet. 2013 Sep 5;93(3):422-38 [23932107.001]
  • [Cites] J Genet. 2008 Apr;87(1):3-20 [18560169.001]
  • [Cites] PLoS Genet. 2012;8(11):e1002967 [23166502.001]
  • [Cites] Gigascience. 2015 Feb 25;4:7 [25722852.001]
  • [Cites] PLoS One. 2015 Jun 10;10(6):e0127655 [26061398.001]
  • [Cites] Genetics. 2012 Nov;192(3):1065-93 [22960212.001]
  • [Cites] Nature. 2010 Sep 2;467(7311):52-8 [20811451.001]
  • [Cites] Hum Genet. 2005 May;116(6):507-17 [15772853.001]
  • [Cites] Curr Biol. 2010 Feb 23;20(4):R184-7 [20178765.001]
  • [Cites] PLoS Genet. 2012 Jan;8(1):e1002453 [22291602.001]
  • [Cites] PLoS One. 2012;7(2):e32546 [22393414.001]
  • [Cites] Science. 2011 Oct 7;334(6052):94-8 [21940856.001]
  • [Cites] Am J Hum Genet. 2007 Nov;81(5):1084-97 [17924348.001]
  • [Cites] Nature. 2014 Jan 2;505(7481):87-91 [24256729.001]
  • [Cites] Hum Biol. 2013 Feb-Jun;85(1-3):251-84 [24297229.001]
  • [Cites] Nature. 2010 Jul 8;466(7303):238-42 [20531471.001]
  • [Cites] Genome Res. 2009 Sep;19(9):1655-64 [19648217.001]
  • [Cites] Science. 2008 Feb 22;319(5866):1100-4 [18292342.001]
  • [Cites] Nature. 2009 Sep 24;461(7263):489-94 [19779445.001]
  • [Cites] PLoS Genet. 2015 Apr 21;11(4):e1005068 [25898006.001]
  • (PMID = 28145430.001).
  • [ISSN] 1476-5438
  • [Journal-full-title] European journal of human genetics : EJHG
  • [ISO-abbreviation] Eur. J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


45. Lowery RK, Herrera KJ, Barrett DA, Rodriguez R, Hadden LR, Harutyunyan A, Margaryan A, Yepiskoposyan L, Herrera RJ: Regionalized autosomal STR profiles among Armenian groups suggest disparate genetic influences. Am J Phys Anthropol; 2011 Oct;146(2):171-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regionalized autosomal STR profiles among Armenian groups suggest disparate genetic influences.
  • Near continual foreign influx has, in turn, led to the supposition that the gene pools of geographically separated Armenian populations may have diverged as differing historical influences potentially left distinct genetic traces in the various regions of the Armenian plateau.
  • In this study, we seek to address whether any evidence for such genetic regional partitioning in Armenians exists by analyzing, for the first time, 15 autosomal short tandem repeat (STR) loci in 404 Armenians from four geographically well-characterized collections (Ararat Valley, Gardman, Sasun, and Lake Van) that represent distinct communities from across Historical Armenia.
  • In addition, to determine whether genetic differences among these four Armenian populations are the result of differential affinities to populations of known historical influence in Armenia, we utilize 27 biogeographically targeted reference populations for phylogenetic and admixture analyses.
  • From these examinations, we find that while close genetic affiliations exist between the two easternmost Armenian groups analyzed, Ararat Valley and Gardman, the remaining two populations display substantial distinctions.
  • In particular, Sasun is distinguished by evidence for genetic contributions from Turkey, while a stronger Balkan component is detected in Lake Van, potentially suggestive of remnant genetic influences from ancient Greek and Phrygian populations in this region.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. European Continental Ancestry Group / genetics. Genetic Variation. Microsatellite Repeats
  • [MeSH-minor] Armenia. Chi-Square Distribution. Genetics, Population. Humans. Phylogeny

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2011 Wiley-Liss, Inc.
  • (PMID = 21826633.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


46. Hizawa N, Ohe M, Kawakami Y: [Genetic analysis of bronchial asthma in Japanese population--Fc epsilon RI beta gene and beta 2 adrenergic receptor gene]. Nihon Rinsho; 1996 Feb;54(2):539-43
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Genetic analysis of bronchial asthma in Japanese population--Fc epsilon RI beta gene and beta 2 adrenergic receptor gene].
  • On the basis of the progression of molecular biology, the genetic regulations of asthma are being examined extensively and, recently, the gene encoding a beta subunit of the high affinity receptor for IgE (Fc epsilon RI beta) and the gene encoding beta 2 adrenergic receptor (beta 2ADR) are considered to be responsible for asthma.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Asthma / genetics. Receptors, Adrenergic, beta / genetics. Receptors, IgE / genetics

  • Genetic Alliance. consumer health - Asthma.
  • MedlinePlus Health Information. consumer health - Asthma.
  • COS Scholar Universe. author profiles.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 8838111.001).
  • [ISSN] 0047-1852
  • [Journal-full-title] Nihon rinsho. Japanese journal of clinical medicine
  • [ISO-abbreviation] Nippon Rinsho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] JAPAN
  • [Chemical-registry-number] 0 / Receptors, Adrenergic, beta; 0 / Receptors, IgE
  • [Number-of-references] 23
  •  go-up   go-down


47. Kenyhercz MW, Klales AR, Kenyhercz WE: Molar size and shape in the estimation of biological ancestry: A comparison of relative cusp location using geometric morphometrics and interlandmark distances. Am J Phys Anthropol; 2014 Feb;153(2):269-79
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cusp apices of maxillary and mandibular first and second molars were digitized from 190 American Blacks and Whites to estimate biological affinity through the shape of relative cusp locations.
  • Centroid size and major shape component group means were compared with t-tests.
  • Procrustes coordinates and the principal components derived from them with and without centroid size, along with the interlandmark distances and the principal components derived from them, were each subjected to a discriminant function analysis to examine which methods yielded the highest correct classification between population groups.
  • [MeSH-major] African Continental Ancestry Group / statistics & numerical data. European Continental Ancestry Group / statistics & numerical data. Molar / anatomy & histology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2013 Wiley Periodicals, Inc.
  • (PMID = 24248428.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Keywords] NOTNLM ; ancestry / dental anthropology / geometric morphometrics discriminant function analysis
  •  go-up   go-down


48. McLean DC Jr, Spruill I, Argyropoulos G, Page GP, Shriver MD, Garvey WT: Mitochondrial DNA (mtDNA) haplotypes reveal maternal population genetic affinities of Sea Island Gullah-speaking African Americans. Am J Phys Anthropol; 2005 Aug;127(4):427-38
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitochondrial DNA (mtDNA) haplotypes reveal maternal population genetic affinities of Sea Island Gullah-speaking African Americans.
  • To better understand the population substructure of African Americans living in coastal South Carolina, we used restriction site polymorphisms and an insertion/deletion in mitochondrial DNA (mtDNA) to construct seven-position haplotypes across 1,395 individuals from Sierra Leone, Africa, from U.S.
  • European Americans, and from the New World African-derived populations of Jamaica, Gullah-speaking African Americans of the South Carolina Sea Islands (Gullahs), African Americans living in Charleston, South Carolina, and West Coast African Americans.
  • Analyses showed a high degree of similarity within the New World African-derived populations, where haplotype frequencies and diversities were similar.
  • Phi-statistics indicated that very little genetic differentiation has occurred within New World African-derived populations, but that there has been significant differentiation of these populations from Sierra Leoneans.
  • [MeSH-major] African Americans / genetics. DNA, Mitochondrial / genetics. Genetic Heterogeneity. Genetics, Population. Haplotypes / genetics. Inheritance Patterns / genetics
  • [MeSH-minor] Anthropology, Physical. European Continental Ancestry Group / genetics. European Continental Ancestry Group / statistics & numerical data. Female. Humans. Jamaica / ethnology. Male. Pacific States / epidemiology. Sierra Leone / ethnology. South Carolina / epidemiology

  • MedlinePlus Health Information. consumer health - African American Health.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2004 Wiley-Liss, Inc.
  • (PMID = 15624208.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK-47461
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


49. Hattori Y, Vera JC, Rivas CI, Bersch N, Bailey RC, Geffner ME, Golde DW: Decreased insulin-like growth factor I receptor expression and function in immortalized African Pygmy T cells. J Clin Endocrinol Metab; 1996 Jun;81(6):2257-63
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Efe Pygmies of northeast Zaire have the shortest mean adult stature of any population on earth.
  • We found markedly decreased cell surface expression of IGF-I receptors with normal ligand binding affinity.
  • The Pygmy IGF-I receptors were not autophosphorylated and did not transmit a signal in response to physiological concentrations of IGF-I.
  • [MeSH-major] Insulin-Like Growth Factor I / metabolism. Oceanic Ancestry Group. Receptors, Somatomedin / metabolism. T-Lymphocytes / metabolism
  • [MeSH-minor] Base Sequence. Cell Line, Transformed. Continental Population Groups. DNA, Complementary / genetics. Democratic Republic of the Congo. Humans. Intracellular Membranes / metabolism. Molecular Probes / genetics. Molecular Sequence Data. RNA, Messenger / metabolism. Signal Transduction

  • MedlinePlus Health Information. consumer health - Native Hawaiian and Pacific Islander Health.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 8964861.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30-CA-08748; United States / NCI NIH HHS / CA / R01-CA-30388
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / Molecular Probes; 0 / RNA, Messenger; 0 / Receptors, Somatomedin; 67763-96-6 / Insulin-Like Growth Factor I
  •  go-up   go-down


50. de Azevedo S, Nocera A, Paschetta C, Castillo L, González M, González-José R: Evaluating microevolutionary models for the early settlement of the New World: the importance of recurrent gene flow with Asia. Am J Phys Anthropol; 2011 Dec;146(4):539-52
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, some aspects concerning the population affinities among early and modern Asians and Native Americans remain controversial.
  • This scenario considers a single origin for all the Native Americans, and local, within-continent evolution plus the persistence of contact among Circum-Arctic groups.
  • Our results suggest a better explanatory performance of the Recurrent Gene Flow model, and provide additional insights concerning affinities among Asian and Native American Circum-Arctic groups.
  • [MeSH-major] American Native Continental Ancestry Group. Asian Continental Ancestry Group. Biological Evolution. Emigration and Immigration. Gene Flow. Skull / anatomy & histology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2011 Wiley Periodicals, Inc.
  • (PMID = 21805463.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


51. Vlassara H: Chronic diabetic complications and tissue glycosylation. Relevant concern for diabetes-prone black population. Diabetes Care; 1990 Nov;13(11):1180-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chronic diabetic complications and tissue glycosylation. Relevant concern for diabetes-prone black population.
  • A significant segment of the Black population is affected by chronic diabetes, and most of them are subjected to severe cardiovascular, renal, and neurological complications that shorten survival and diminish quality of life.
  • Such protein-glucose interactions, called advanced glycosylation end products (AGEs), are processed by macrophages through a high-affinity receptor.
  • [MeSH-major] African Continental Ancestry Group. Diabetes Mellitus / physiopathology

  • Genetic Alliance. consumer health - Diabetes.
  • MedlinePlus Health Information. consumer health - Diabetes.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 2261839.001).
  • [ISSN] 0149-5992
  • [Journal-full-title] Diabetes care
  • [ISO-abbreviation] Diabetes Care
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] UNITED STATES
  • [Number-of-references] 47
  •  go-up   go-down


52. Wang L, Ren Y, Shi X, Yuan D, Liu K, Geng T, Li G, Kang L, Jin TB: The population genetics of pharmacogenomics VIP variants in the Sherpa population. Drug Metab Pharmacokinet; 2016 Feb;31(1):82-89
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The population genetics of pharmacogenomics VIP variants in the Sherpa population.
  • Particularly, there is a paucity of pharmacogenetic information in the Sherpa population in Tibet.
  • We used the Sequenom MassARRAY single nucleotide polymorphism (SNP) genotyping technology to detect 86 very important pharmacogene (VIP) variants in Sherpas and compared the genotypic frequencies of these variants with HapMap populations.
  • Overall, 59 of the 60 previously reported variants in the HapMap populations were found in our study.
  • We found minimal differences between populations of Sherpas and Chinese Han in Beijing (CHB), Chinese in Metropolitan Denver, Colorado (CHD), Japanese in Tokyo, Japan (JPT), and Mexicans in Los Angeles, California (MEX) after a strict Bonferroni correction.
  • Only 8, 4, 5, 4 VIP genotypes, respectively, were different in these groups.
  • Additionally, pairwise FST values and clustering analyses showed that the VIP variants in the Sherpa population exhibited a close genetic affinity with the CHB and JPT populations, but they were most similar to the CHD population.
  • Our results contribute to a better understanding of the molecular basis underlying ethnic differences in drug response, which may potentially benefit the development of personalized medicine for the Sherpa population.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Genome, Human / genetics. Polymorphism, Single Nucleotide / genetics
  • [MeSH-minor] Alleles. Beijing. Female. Gene Frequency / genetics. Genetics, Population / methods. Genotype. Humans. Japan. Male. Pharmacogenetics / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2015 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 26825850.001).
  • [ISSN] 1880-0920
  • [Journal-full-title] Drug metabolism and pharmacokinetics
  • [ISO-abbreviation] Drug Metab. Pharmacokinet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Keywords] NOTNLM ; Clustering analyses / Ethnic difference / Pairwise F(ST) values / Pharmacogenomics / Sherpa / VIP variants
  •  go-up   go-down


53. Chahal SM, Virk RK, Kaur S, Bansal R: Social stratification in the Sikh population of Punjab (India) has a genetic basis: evidence from serological and biochemical markers. Genet Test Mol Biomarkers; 2011 Jul-Aug;15(7-8):543-56
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Social stratification in the Sikh population of Punjab (India) has a genetic basis: evidence from serological and biochemical markers.
  • AIM OF THE STUDY: The present study was planned to assess whether social stratification in the Sikh population inhabiting the northwest border Indian state of Punjab has any genetic basis.
  • SUBJECTS AND MATERIALS: Blood samples were collected randomly from a total of 2851 unrelated subjects belonging to 21 groups of two low-ranking Sikh scheduled caste populations, viz.
  • Mazhabi and Ramdasi, and a high-ranking Jat Sikh caste population of Punjab.
  • METHODS: The genetic profile of Sikh groups was investigated using a total of nine serobiochemical genetic markers, comprising two blood groups (ABO, RH(D)) and a battery of seven red cell enzyme polymorphisms (ADA, AK1, ESD, PGM1, GLO1, ACP1, GPI), following standard serological and biochemical laboratory protocols.
  • RESULTS: Great heterogeneity was observed between Sikh scheduled caste and Jat Sikh populations, especially in the RH(D) blood group system, and distribution of ESD, ACP1, and PGM1 enzyme markers was also found to be significantly different between many of their groups.
  • Genetic distance trees demonstrated little or no genetic affinities between Sikh scheduled caste and Jat Sikh populations; the Mazhabi and Ramdasi also showed little genetic relationship.
  • CONCLUSIONS: The present study revealed much genetic heterogeneity in differently ranking Sikh caste populations of Punjab, mainly attributable to their different ethnic backgrounds, and provided a genetic basis to social stratification present in this religious community of Punjab, India.
  • [MeSH-major] ABO Blood-Group System / genetics. Biomarkers. European Continental Ancestry Group / genetics. Polymorphism, Genetic. Rh-Hr Blood-Group System / genetics. Social Class
  • [MeSH-minor] Carboxylesterase / genetics. Erythrocytes / enzymology. Female. Genetics, Population. Humans. India / ethnology. Male. Phosphoglucomutase / genetics. Protein Tyrosine Phosphatases / genetics. Proto-Oncogene Proteins / genetics

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21453054.001).
  • [ISSN] 1945-0257
  • [Journal-full-title] Genetic testing and molecular biomarkers
  • [ISO-abbreviation] Genet Test Mol Biomarkers
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ABO Blood-Group System; 0 / Biomarkers; 0 / Proto-Oncogene Proteins; 0 / Rh-Hr Blood-Group System; 0 / Rho(D) antigen; EC 3.1.1.1 / Carboxylesterase; EC 3.1.1.1 / ESD protein, human; EC 3.1.3.48 / ACP1 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 5.4.2.2 / PGM1 protein, human; EC 5.4.2.2 / Phosphoglucomutase
  •  go-up   go-down


54. Miyauchi M, Kishida I, Suda A, Shiraishi Y, Hattori S, Fujibayashi M, Taguri M, Ishii C, Ishii N, Moritani T, Hirayasu Y: Association of the Cholinergic Muscarinic M2 Receptor with Autonomic Nervous System Activity in Patients with Schizophrenia on High-Dose Antipsychotics. Neuropsychobiology; 2016;74(1):60-67
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Patients with schizophrenia have abnormal autonomic nervous system (ANS) activity compared with the general population.
  • One reason for this difference is the muscarinic affinity for antipsychotic drugs; therefore, single nucleotide polymorphisms (SNPs) of the muscarinic receptor gene influence this ANS dysfunction.
  • Patients were grouped according to standard equivalent conversions of chlorpromazine (CP) into a high-CP group (HG; ≥1,000 mg) and a low-CP group (LG; <1,000 mg).
  • ANS activity was compared between the groups.
  • In addition, we compared the total, low-frequency (LF), high-frequency (HF), and LF/HF components of the patients' HRV, and the genotype of the SNPs in both the HG and LG groups.
  • [MeSH-minor] Adult. Antipsychotic Agents / therapeutic use. Asian Continental Ancestry Group / genetics. Autonomic Nervous System / physiopathology. Female. Genotype. Humans. Japan. Male. Middle Aged. Polymorphism, Single Nucleotide

  • Genetic Alliance. consumer health - Schizophrenia.
  • MedlinePlus Health Information. consumer health - Schizophrenia.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2016 S. Karger AG, Basel.
  • (PMID = 27923235.001).
  • [ISSN] 1423-0224
  • [Journal-full-title] Neuropsychobiology
  • [ISO-abbreviation] Neuropsychobiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antipsychotic Agents; 0 / CHRM1 protein, human; 0 / CHRM2 protein, human; 0 / CHRM3 protein, human; 0 / Receptor, Muscarinic M2; 0 / Receptors, Muscarinic
  •  go-up   go-down


55. Fuchs J, Pons JM, Goodman SM, Bretagnolle V, Melo M, Bowie RC, Currie D, Safford R, Virani MZ, Thomsett S, Hija A, Cruaud C, Pasquet E: Tracing the colonization history of the Indian Ocean scops-owls (Strigiformes: Otus) with further insight into the spatio-temporal origin of the Malagasy avifauna. BMC Evol Biol; 2008;8:197
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Deciphering which factor explains the current distributional pattern of a given taxonomic group requires robust phylogenies as well as estimates of divergence times.
  • The lineage of Indian Ocean scops-owls (Otus: Strigidae) includes six or seven species that are endemic to Madagascar and portions of the Comoros and Seychelles archipelagos; little is known about the species limits, biogeographic affinities and relationships to each other.
  • RESULTS: Our analyses revealed that Indian Ocean islands scops-owls do not form a monophyletic assemblage: the Seychelles Otus insularis is genetically closer to the South-East Asian endemic O. sunia than to species from the Comoros and Madagascar.
  • The Pemba Scops-owls O. pembaensis, often considered closely related to, if not conspecific with O. rutilus of Madagascar, is instead closely related to the African mainland O. senegalensis.
  • Our divergence date estimates, using a Bayesian relaxed clock method, suggest that all these events occurred during the last 3.6 myr; albeit colonization of the Indian Ocean islands were not synchronous, O. pembaensis diverged from O. senegalensis about 1.7 mya while species from Madagascar and the Comoro diverged from their continental sister-group about 3.6 mya.
  • [MeSH-minor] Animals. DNA, Intergenic / genetics. DNA, Mitochondrial / genetics. Geography. Indian Ocean. Madagascar. Molecular Sequence Data. Population Dynamics. Sequence Analysis, DNA. Time Factors

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Evolution. 2001 Jun;55(6):1198-206 [11475055.001]
  • [Cites] Bioinformatics. 2001 Aug;17(8):754-5 [11524383.001]
  • [Cites] Nature. 2002 Feb 14;415(6873):784-7 [11845207.001]
  • [Cites] Science. 2002 Mar 1;295(5560):1683 [11872833.001]
  • [Cites] Genetics. 2002 Jul;161(3):1307-20 [12136032.001]
  • [Cites] Hereditas. 2002;136(3):254-6 [12471675.001]
  • [Cites] Mol Biol Evol. 1998 Nov;15(11):1568-71 [12572620.001]
  • [Cites] Nature. 2003 Feb 13;421(6924):734-7 [12610623.001]
  • [Cites] Bioinformatics. 2003 Aug 12;19(12):1572-4 [12912839.001]
  • [Cites] Mol Phylogenet Evol. 2003 Oct;29(1):67-85 [12967608.001]
  • [Cites] Syst Biol. 2003 Oct;52(5):696-704 [14530136.001]
  • [Cites] Proc Biol Sci. 2003 Dec 7;270(1532):2435-42 [14667332.001]
  • [Cites] Proc Biol Sci. 2003 Dec 22;270(1533):2613-21 [14728785.001]
  • [Cites] J Mol Biol. 1990 Apr 20;212(4):599-634 [2329578.001]
  • [Cites] Trends Genet. 1993 Dec;9(12):407 [8122306.001]
  • [Cites] Mol Ecol. 1993 Dec;2(6):359-73 [7909260.001]
  • [Cites] Electrophoresis. 1998 Feb;19(2):142-51 [9548272.001]
  • [Cites] Mol Phylogenet Evol. 1999 Jul;12(2):105-14 [10381314.001]
  • [Cites] Proc Biol Sci. 2005 Apr 22;272(1565):849-58 [15888418.001]
  • [Cites] Syst Biol. 2005 Apr;54(2):241-53 [16012095.001]
  • [Cites] Nature. 2005 Nov 10;438(7065):216-9 [16281034.001]
  • [Cites] PLoS Biol. 2006 May;4(5):e88 [16683862.001]
  • [Cites] Mol Phylogenet Evol. 2006 Nov;41(2):333-44 [16806992.001]
  • [Cites] Mol Ecol. 2006 Oct;15(12):3769-86 [17032273.001]
  • [Cites] Mol Phylogenet Evol. 2007 Feb;42(2):422-34 [16971142.001]
  • [Cites] Biol Lett. 2006 Dec 22;2(4):543-7 [17148284.001]
  • [Cites] Mol Phylogenet Evol. 2007 Jul;44(1):138-53 [17123839.001]
  • [Cites] Syst Biol. 2007 Aug;56(4):643-55 [17661232.001]
  • [Cites] Mol Phylogenet Evol. 2007 Oct;45(1):158-67 [17468015.001]
  • (PMID = 18611281.001).
  • [ISSN] 1471-2148
  • [Journal-full-title] BMC evolutionary biology
  • [ISO-abbreviation] BMC Evol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Intergenic; 0 / DNA, Mitochondrial
  • [Other-IDs] NLM/ PMC2483963
  •  go-up   go-down


56. Movsesian AA: Nonmetric cranial trait variation and population history of medieval East Slavic tribes. Am J Phys Anthropol; 2013 Dec;152(4):495-505
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonmetric cranial trait variation and population history of medieval East Slavic tribes.
  • The population history of the East Slavs is complicated.
  • (1) to assess the degree of biological affinity in medieval East Slavic tribes and to test the hypothesis that East Slavic peoples have a common origin;.
  • (2) to show their genetic connections to the autochthonous populations of the northern part of Eastern Europe (Baltic and Finno-Ugric tribes); and (3) to identify a genetic continuity between the bearers of Chernyakhov culture and medieval Eastern Slavs. In this study, nonmetric cranial trait data for medieval East Slavic tribes and comparative samples from unrelated groups were examined.
  • The results obtained suggest that the genetic affinity of the East Slavic tribes is due not only to inter-tribal gene flow, but is, more importantly, a result of their common population history.
  • Evidence of gene flow from the Baltic and Finno-Ugric groups was showed in the gene pool of Eastern Slavs, as was genetic continuity between medieval East Slavic tribes and the populations of the preceding Chernyakhov culture.
  • [MeSH-major] Ethnic Groups. European Continental Ancestry Group. Phenotype. Skull / anatomy & histology
  • [MeSH-minor] Discriminant Analysis. Europe, Eastern. Humans. Population Dynamics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2013 Wiley Periodicals, Inc.
  • (PMID = 24136162.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Balts / Chernyakhov culture / East Slavs / Finno-Ugrics / GST statistics / Nei's genetic distance / gene pool / phenotype
  •  go-up   go-down


57. Yokley TR, Churchill SE: Archaic and modern human distal humeral morphology. J Hum Evol; 2006 Dec;51(6):603-16
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Accordingly, the morphology of adjacent, articulating elements should be able to distinguish these two broad groups as well.
  • In addition, the morphological affinities of Broken Hill (Kabwe) E.898, an archaic human distal humeral fragment from the middle Pleistocene of Zambia, and five Pliocene and early Pleistocene australopith humeri were assessed.
  • The morphometric analyses effectively differentiated the Neandertals from the other groups, while the Broken Hill humerus appears morphologically similar to modern human distal humeri.
  • Thus, an archaic/modern human dichotomy-as previously reported for proximal ulnar morphology-is not supported with respect to distal humeral morphology.
  • The seeming disparity in morphological affinities of proximal ulnae (in which all archaic human groups appear distinct from modern humans) and distal humeri (in which Neandertals appear distinct from modern humans, but other archaic humans do not) is probably indicative of a highly variable, possibly transitional population of which our knowledge is hampered by sample-size limitations imposed by the scarcity of middle-to-late Pleistocene premodern human fossils outside of Europe.
  • [MeSH-minor] African Continental Ancestry Group. Animals. Anthropometry. Cluster Analysis. Ethnic Groups. European Continental Ancestry Group. Female. History, Ancient. Humans. Male. Principal Component Analysis. Species Specificity

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16959299.001).
  • [ISSN] 0047-2484
  • [Journal-full-title] Journal of human evolution
  • [ISO-abbreviation] J. Hum. Evol.
  • [Language] eng
  • [Publication-type] Comparative Study; Historical Article; Journal Article
  • [Publication-country] England
  •  go-up   go-down


58. Shikanai T, Silverman ES, Morse BW, Lilly CM, Inoue H, Drazen JM: Sequence variants in the FcepsilonRI alpha chain gene. J Appl Physiol (1985); 2002 Jul;93(1):37-41
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There is a relationship between IgE levels and expression of high-affinity IgE receptors (FcepsilonRI).
  • An analysis of highly polymorphic SNPs indicated that this association is unlikely to be due to population substructure.
  • [MeSH-minor] African Continental Ancestry Group. Asthma / genetics. European Continental Ancestry Group. Exons / genetics. Genotype. Humans. Immunoglobulin E / biosynthesis. Immunoglobulin E / genetics. Introns / genetics. Polymorphism, Single-Stranded Conformational. Population. Promoter Regions, Genetic / genetics. Reverse Transcriptase Polymerase Chain Reaction

  • COS Scholar Universe. author profiles.
  • Pharmacogenomics Knowledge Base. meta-databases - Pharmacogenomic Annotation 827850507 for PMID:12070183 [PharmGKB] .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12070183.001).
  • [ISSN] 8750-7587
  • [Journal-full-title] Journal of applied physiology (Bethesda, Md. : 1985)
  • [ISO-abbreviation] J. Appl. Physiol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, IgE; 37341-29-0 / Immunoglobulin E; 9007-49-2 / DNA
  •  go-up   go-down


59. Wu SN, Gao R, Xing QH, Li HF, Shen YF, Gu NF, Feng GY, He L: Association of DRD2 polymorphisms and chlorpromazine-induced extrapyramidal syndrome in Chinese schizophrenic patients. Acta Pharmacol Sin; 2006 Aug;27(8):966-70
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIM: Extrapyramidal syndrome (EPS) is most commonly affected by typical antipsychotic drugs that have a high affinity with the D2 receptor.
  • Recently, many research groups have reported on the positive relationship between the genetic variations in the DRD2 gene and the therapeutic response in schizophrenia patients as a result of the role of variations in the receptor in modulating receptor expression.
  • RESULTS: Polymorphisms TaqID, Ser311Cys and rs6277 were not polymorphic in the population recruited in the present study.
  • No statistical significance was found in the allele distribution of -141Cins>del, TaqIB, rs6275 and TaqIA or in the estimated haplotypes (constituted by TaqIB, rs6275 and TaqIA) in linkage disequilibrium between the two groups.
  • CONCLUSION: Our results did not lend strong support to the view that the genetic variation of the DRD2 gene plays a major role in the individually variable adverse effect induced by chlorpromazine, at least in Chinese patients with schizophrenia.
  • [MeSH-minor] Adult. Alleles. Antipsychotic Agents / adverse effects. Asian Continental Ancestry Group. Dystonia / chemically induced. Dystonia / genetics. Female. Genotype. Haplotypes. Humans. Linkage Disequilibrium. Male

  • MedlinePlus Health Information. consumer health - Schizophrenia.
  • Hazardous Substances Data Bank. Chlorpromazine .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16867246.001).
  • [ISSN] 1671-4083
  • [Journal-full-title] Acta pharmacologica Sinica
  • [ISO-abbreviation] Acta Pharmacol. Sin.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antipsychotic Agents; 0 / Receptors, Dopamine D2; U42B7VYA4P / Chlorpromazine
  •  go-up   go-down


60. Oettlé AC, Becker PJ, de Villiers E, Steyn M: The influence of age, sex, population group, and dentition on the mandibular angle as measured on a South African sample. Am J Phys Anthropol; 2009 Aug;139(4):505-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The influence of age, sex, population group, and dentition on the mandibular angle as measured on a South African sample.
  • The mandibular angle is measured in physical anthropological assessments of human remains to possibly assist with the determination of sex and population affinity.
  • The purpose of this investigation was to establish how the mandibular angle changes with age and loss of teeth among the sexes in South African population groups.
  • No association was found between age and angle within either of the populations, within sexes, or within dentition groups.
  • The angle was the most obtuse in individuals without molars and with an uneven distribution of molars, and most acute in the group with an even distribution of molars on both sides.
  • Statistically significant differences (P < 0.001) were found in the angle between the two population groups and sexes in the overall sample as well as in the subgroup with absent molar teeth (P = 0.003 for sex, males more acute angle, and P = 0.001 for population group, blacks more acute angle), although a very large overlap existed.
  • No significant differences could be demonstrated between the sexes or populations within the subgroups with molars.
  • In the assessment of human remains, the mandibular angle is not very usable in determining sex.
  • [MeSH-minor] Adult. African Continental Ancestry Group. Age Factors. Aged. Aged, 80 and over. Analysis of Variance. Anthropology, Physical. Anthropometry. European Continental Ancestry Group. Female. Humans. Male. Middle Aged. Sex Factors. South Africa

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19235793.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


61. Horai S, Murayama K, Hayasaka K, Matsubayashi S, Hattori Y, Fucharoen G, Harihara S, Park KS, Omoto K, Pan IH: mtDNA polymorphism in East Asian Populations, with special reference to the peopling of Japan. Am J Hum Genet; 1996 Sep;59(3):579-90
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] mtDNA polymorphism in East Asian Populations, with special reference to the peopling of Japan.
  • Nucleotide sequences of the major noncoding (D-loop) region of human mtDNA from five East Asian populations including mainland Japanese, Ainu, Ryukyuans, Koreans, and Chinese were analyzed.
  • Of these, 189 were unique to their respective populations, whereas 18 were shared between two or three populations.
  • The intergenic COII/tRNA(Lys) 9-bp deletion was observed in every East Asian population with varying frequencies.
  • Phylogenetic analysis revealed that East Asian lineages were classified into at least 18 monophyletic clusters, though lineages from the five populations were completely intermingled in the phylogenetic tree.
  • However, we assigned 14 of the 18 clusters for their specificity on the basis of the population from which the maximum number of individuals in each cluster was derived.
  • Of note is the finding that 50% of the mainland Japanese had continental specificity in which Chinese or Koreans were dominant, while < 20% of either Ryukyuans or Ainu possessed continental specificity.
  • Phylogenetic analysis of the entire human population revealed the closest genetic affinity between the mainland Japanese and Koreans.
  • It is suggested that approximately 65% of the gene pool in mainland Japanese was derived from the continental gene flow after the Yayoi Age.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. DNA, Mitochondrial / genetics. Polymorphism, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Science. 1969 Aug 22;165(3895):762-8 [4894336.001]
  • [Cites] Hum Biol. 1994 Aug;66(4):567-90 [7916319.001]
  • [Cites] Science. 1976 Sep 3;193(4256):911-3 [781841.001]
  • [Cites] Proc Natl Acad Sci U S A. 1979 Apr;76(4):1967-71 [109836.001]
  • [Cites] Proc Natl Acad Sci U S A. 1980 Jun;77(6):3605-9 [6251473.001]
  • [Cites] Proc Natl Acad Sci U S A. 1980 Nov;77(11):6715-9 [6256757.001]
  • [Cites] J Mol Evol. 1980 Dec;16(2):111-20 [7463489.001]
  • [Cites] Nature. 1981 Apr 9;290(5806):457-65 [7219534.001]
  • [Cites] Hum Genet. 1986 Feb;72(2):105-17 [3002958.001]
  • [Cites] Nature. 1987 Jan 1-7;325(6099):31-6 [3025745.001]
  • [Cites] Science. 1988 Jan 29;239(4839):487-91 [2448875.001]
  • [Cites] Mol Biol Evol. 1987 Jul;4(4):406-25 [3447015.001]
  • [Cites] Am J Hum Genet. 1988 Aug;43(2):134-43 [2840820.001]
  • [Cites] Am J Hum Genet. 1989 Apr;44(4):504-10 [2929595.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Aug;86(16):6196-200 [2762322.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Dec;86(23):9350-4 [2594772.001]
  • [Cites] Hum Hered. 1989;39(5):276-81 [2613254.001]
  • [Cites] Am J Hum Genet. 1990 Mar;46(3):613-23 [1968708.001]
  • [Cites] Am J Hum Genet. 1990 Apr;46(4):828-42 [2316527.001]
  • [Cites] Genetics. 1990 Aug;125(4):873-9 [1975792.001]
  • [Cites] Science. 1991 Sep 27;253(5027):1503-7 [1840702.001]
  • [Cites] Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8720-4 [1681540.001]
  • [Cites] Philos Trans R Soc Lond B Biol Sci. 1991 Sep 30;333(1268):409-16; discussion 416-7 [1684051.001]
  • [Cites] Genetics. 1992 Jan;130(1):139-52 [1346259.001]
  • [Cites] Genetics. 1992 Jan;130(1):153-62 [1346260.001]
  • [Cites] Am J Hum Genet. 1992 Apr;50(4):758-65 [1550120.001]
  • [Cites] Am J Hum Genet. 1993 Sep;53(3):549-62 [8352271.001]
  • [Cites] Am J Hum Genet. 1993 Sep;53(3):609-18 [8102506.001]
  • [Cites] Mol Biol Evol. 1993 Sep;10(5):927-43 [8412653.001]
  • [Cites] Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10663-7 [8248157.001]
  • [Cites] Am J Hum Genet. 1994 Feb;54(2):303-18 [8304347.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):532-6 [7530363.001]
  • [Cites] Am J Hum Genet. 1995 Apr;56(4):951-62 [7717406.001]
  • [Cites] Mol Biol Evol. 1995 Jul;12(4):604-15 [7659016.001]
  • [Cites] Am J Hum Genet. 1995 Aug;57(2):201-23 [7668244.001]
  • [Cites] Hum Biol. 1992 Apr;64(2):161-6 [1559687.001]
  • [Cites] Mol Biol Evol. 1993 Jan;10(1):23-47 [7680748.001]
  • [Cites] Proc Biol Sci. 1993 May 22;252(1334):163-70 [8391704.001]
  • [Cites] Nature. 1994 Mar 31;368(6470):455-7 [7510853.001]
  • [Cites] Nature. 1974 Oct 11;251(5475):536-8 [4423884.001]
  • (PMID = 8751859.001).
  • [ISSN] 0002-9297
  • [Journal-full-title] American journal of human genetics
  • [ISO-abbreviation] Am. J. Hum. Genet.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ D84723/ D84724/ D84725/ D84726/ D84727/ D84728/ D84729/ D84730/ D84731/ D84732/ D84733/ D84734/ D84735/ D84736/ D84737/ D84738/ D84739/ D84740/ D84741/ D84742/ D84743/ D84744/ D84745/ D84746/ D84747/ D84748/ D84749/ D84750/ D84751/ D84752; etc
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / RNA, Transfer, Lys; EC 1.9.3.1 / Electron Transport Complex IV
  • [Other-IDs] NLM/ PMC1914908
  •  go-up   go-down


62. Yao YS, Li J, Jin YL, He LP, Chang WW, Chen Y, Ding LL, Lu W, Li CP: Association between FcεRIβ and IFN-γ Polymorphisms and Asthma in Asian Population: a Meta-Analysis. Iran J Allergy Asthma Immunol; 2015 Feb;14(1):1-11
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association between FcεRIβ and IFN-γ Polymorphisms and Asthma in Asian Population: a Meta-Analysis.
  • Polymorphisms in the β subunit of the high affinity receptor for IgE (FcεRIβ) and interferon-γ (IFN-γ) genes may influence the risk of asthma.
  • However, the results in Asian population are still debatable.
  • We performed a meta-analysis to ascertain the association between the FcεRIβ E237G, FcεRIβ -109C/T, and IFN-γ 874T/A polymorphisms and asthma in an Asian population.
  • This meta-analysis suggested that FcεRIβ E237G is not an influencing factor for asthma in Asian population.
  • FcεRIβ -109C/T and IFN-γ 874T/A polymorphisms may be influencing factors for asthma in the Asian population.
  • [MeSH-minor] Asian Continental Ancestry Group. Humans

  • Genetic Alliance. consumer health - Asthma.
  • MedlinePlus Health Information. consumer health - Asthma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 25530133.001).
  • [ISSN] 1735-1502
  • [Journal-full-title] Iranian journal of allergy, asthma, and immunology
  • [ISO-abbreviation] Iran J Allergy Asthma Immunol
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
  • [Publication-country] Iran
  • [Chemical-registry-number] 0 / MS4A2 protein, human; 0 / Receptors, IgE; 82115-62-6 / Interferon-gamma
  •  go-up   go-down


63. Sudo S, Kudo M, Wada S, Sato O, Hsueh AJ, Fujimoto S: Genetic and functional analyses of polymorphisms in the human FSH receptor gene. Mol Hum Reprod; 2002 Oct;8(10):893-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In a population of 522 Japanese women, the overall frequency of TN/TN (NN), TN/AS (NS), and AS/AS (SS) was 41.0, 46.9 and 12.1% respectively.
  • In polycystic ovary patients, the NS population was significantly larger when compared with the spontaneously ovulating group (66.7 versus 43.5%, P < 0.05).
  • In the SS group, a significantly higher (46%) basal level of serum FSH was observed as compared with that in the NS group (P < 0.05).
  • A higher dose of the exogenous gonadotrophin was required to achieve ovulation induction in the SS group as compared with the NS group (P < 0.05).
  • At the time of hCG administration, estradiol levels per oocyte retrieved for IVF in the SS group were significantly lower as compared with the levels in the NS and NN groups (P < 0.05).
  • There were no significant differences in FSH-stimulated cAMP production and PI turnover as well as ligand-binding affinity between the two receptor isoforms when overexpressed in transfected 293T cells.
  • [MeSH-minor] Alleles. Asian Continental Ancestry Group / genetics. Cells, Cultured. Codon. Cyclic AMP / metabolism. Estradiol / blood. Female. Fertilization in Vitro. Follicle Stimulating Hormone / metabolism. Follicle Stimulating Hormone / pharmacology. Gene Frequency. Genital Diseases, Female / genetics. Humans. Japan. Ovarian Follicle / cytology. Ovulation Induction. Phosphatidylinositols / metabolism. Polycystic Ovary Syndrome / genetics


64. Li K, Zhao B, Dai D, Yao S, Liang W, Yao L, Yang Z: A functional p.82G&gt;S polymorphism in the RAGE gene is associated with multiple sclerosis in the Chinese population. Mult Scler; 2011 Aug;17(8):914-21
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A functional p.82G>S polymorphism in the RAGE gene is associated with multiple sclerosis in the Chinese population.
  • A functional polymorphism within the V-type immunoglobulin domain of RAGE gene, p.82G>S (c.557G>A), has been shown to affect ligand binding affinity and thus may affect susceptibility to MS.
  • CONCLUSIONS: The present study provides preliminary evidence that the gain-of-function p.82G>S polymorphism in the RAGE gene is associated with an increased risk of MS in the Chinese population.
  • [MeSH-major] Advanced Glycosylation End Product-Specific Receptor / genetics. Asian Continental Ancestry Group / genetics. Genetic Predisposition to Disease / genetics. Multiple Sclerosis / genetics. Polymorphism, Single Nucleotide

  • Genetic Alliance. consumer health - Multiple Sclerosis.
  • MedlinePlus Health Information. consumer health - Multiple Sclerosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21511691.001).
  • [ISSN] 1477-0970
  • [Journal-full-title] Multiple sclerosis (Houndmills, Basingstoke, England)
  • [ISO-abbreviation] Mult. Scler.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Advanced Glycosylation End Product-Specific Receptor
  •  go-up   go-down


65. Wang HW, Li YC, Sun F, Zhao M, Mitra B, Chaudhuri TK, Regmi P, Wu SF, Kong QP, Zhang YP: Revisiting the role of the Himalayas in peopling Nepal: insights from mitochondrial genomes. J Hum Genet; 2012 Apr;57(4):228-34
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To trace the origin of the Nepalese maternal genetic components, especially those of East Eurasian ancestry, and then to better understand the role of the Himalayas in peopling Nepal, we have studied the matenal genetic composition extensively, especially the East Eurasian lineages, in Nepalese and its surrounding populations.
  • Our results revealed the closer affinity between the Nepalese and the Tibetans, specifically, the Nepalese lineages of the East Eurasian ancestry generally are phylogenetically closer with the ones from Tibet, albeit a few mitochondrial DNA haplotypes, likely resulted from recent gene flow, were shared between the Nepalese and northeast Indians.
  • [MeSH-major] DNA, Mitochondrial / genetics. Genetics, Population. Genome, Human. Genome, Mitochondrial. Mitochondria / genetics
  • [MeSH-minor] Asian Continental Ancestry Group / genetics. Chromosomes, Human, Y / genetics. Gene Flow. Haplotypes. Humans. India. Nepal. Phylogeny. Principal Component Analysis. Sequence Analysis, DNA. Tibet. Time Factors

  • Nature Publishing Group. Nature Publishing Group (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 22437208.001).
  • [ISSN] 1435-232X
  • [Journal-full-title] Journal of human genetics
  • [ISO-abbreviation] J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


66. Yao YG, Zhang YP: Phylogeographic analysis of mtDNA variation in four ethnic populations from Yunnan Province: new data and a reappraisal. J Hum Genet; 2002;47(6):311-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phylogeographic analysis of mtDNA variation in four ethnic populations from Yunnan Province: new data and a reappraisal.
  • Two sets of mitochondrial DNA (mtDNA) hypervariable segment I (HVS-I) data from four ethnic populations (Tibetan, Va, Dai, and Lahu) from Yunnan Province, China, were analyzed here by using phylogeographic methods.
  • The results suggest that more attention should be paid to sampling methodology when addressing the genetic relationship and affinity among ethnic populations.
  • Comparison of related data from different labs may serve as a check for the credibility of the data and will help discern the origin of the ethnic populations.
  • Generally, Tibetan populations have more north-prevalent haplogroups (clades of the mtDNA phylogeny), while Dai and Lahu populations have high frequencies of south-prevalent haplogroups.
  • The Vas, although autochthonous according to historical records, show signs of gene admixtures from northern and southern populations, for they harbor high frequencies of the south-prevalent haplogroup F and the north-prevalent haplogroup D as well as other northern mtDNA lineages such as M9 and G2a.
  • The consanguineous marriage customs of the Lahu, together with possible genetic drift during this group's historical migration, left a conspicuous genetic imprint on its current gene pool.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. DNA, Mitochondrial / genetics. Genetic Variation. Genotype. Phylogeny
  • [MeSH-minor] China / ethnology. Emigration and Immigration. Ethnic Groups. Gene Frequency. Gene Pool. Genetics, Population. Geography. Haplotypes. Humans. Molecular Sequence Data. Polymorphism, Genetic. Sequence Analysis, DNA. Sequence Deletion

  • Nature Publishing Group. Nature Publishing Group (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12111379.001).
  • [ISSN] 1434-5161
  • [Journal-full-title] Journal of human genetics
  • [ISO-abbreviation] J. Hum. Genet.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AF478609/ AF478610/ AF478611/ AF478612/ AF478613/ AF478614/ AF478615/ AF478616/ AF478617/ AF478618/ AF478619/ AF478620/ AF478621/ AF478622/ AF478623/ AF478624/ AF478625/ AF478626/ AF478627/ AF478628/ AF478629/ AF478630/ AF478631/ AF478632/ AF478633/ AF478634/ AF478635/ AF478636/ AF478637/ AF478638/ AF478639/ AF478640/ AF478641/ AF478642/ AF478643/ AF478644/ AF478645/ AF478646/ AF478647/ AF478648/ AF478649/ AF478650/ AF478651/ AF478652/ AF478653/ AF478654/ AF478655/ AF478656/ AF478657/ AF478658/ AF478659/ AF478660/ AF478661/ AF478662/ AF478663/ AF478664/ AF478665/ AF478666/ AF478667/ AF478668/ AF478669/ AF478670/ AF478671/ AF478672/ AF478673/ AF478674/ AF478675/ AF478676/ AF478677/ AF478678/ AF478679/ AF478680/ AF478681/ AF478682
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


67. Xu J, Yin Z, Gao W, Liu L, Yin Y, Liu P, Shu Y: Genetic variation in a microRNA-502 minding site in SET8 gene confers clinical outcome of non-small cell lung cancer in a Chinese population. PLoS One; 2013;8(10):e77024
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic variation in a microRNA-502 minding site in SET8 gene confers clinical outcome of non-small cell lung cancer in a Chinese population.
  • BACKGROUND: Genetic variants may influence microRNA-target interaction through modulate their binding affinity, creating or destroying miRNA-binding sites.
  • [MeSH-minor] 3' Untranslated Regions. Adult. Aged. Asian Continental Ancestry Group / genetics. Base Sequence. Binding Sites. China. Female. Gene Expression. Genotype. Humans. Male. Middle Aged. Neoplasm Staging. Polymorphism, Genetic. Prognosis. Risk Factors

  • Genetic Alliance. consumer health - Lung Cancer.
  • Genetic Alliance. consumer health - Non-small cell lung cancer.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Natl Cancer Inst. 2002 May 1;94(9):681-90 [11983757.001]
  • [Cites] Oncogene. 2013 Mar 21;32(12):1570-9 [22580605.001]
  • [Cites] Curr Biol. 2002 Jul 9;12(13):1086-99 [12121615.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2003 Jun;12(6):527-33 [12814998.001]
  • [Cites] Cell. 2004 Jan 23;116(2):281-97 [14744438.001]
  • [Cites] J Clin Oncol. 2004 Jul 1;22(13):2594-601 [15173214.001]
  • [Cites] Nature. 2004 Sep 16;431(7006):343-9 [15372041.001]
  • [Cites] Am J Surg Pathol. 1993 Mar;17(3):213-20 [8434702.001]
  • [Cites] CA Cancer J Clin. 2005 Mar-Apr;55(2):74-108 [15761078.001]
  • [Cites] Nat Genet. 2005 Apr;37(4):391-400 [15765097.001]
  • [Cites] J Biol Chem. 2005 Aug 26;280(34):30025-31 [15964846.001]
  • [Cites] Nat Rev Cancer. 2005 Nov;5(11):845-56 [16239904.001]
  • [Cites] Genes Dev. 2006 Mar 1;20(5):515-24 [16510870.001]
  • [Cites] Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W451-4 [16845047.001]
  • [Cites] Nat Rev Cancer. 2006 Nov;6(11):857-66 [17060945.001]
  • [Cites] Cell. 2007 Feb 23;128(4):683-92 [17320506.001]
  • [Cites] Hum Mol Genet. 2007 May 1;16(9):1124-31 [17400653.001]
  • [Cites] Nucleic Acids Res. 2007;35(13):4535-41 [17584784.001]
  • [Cites] Mol Cell. 2007 Aug 17;27(4):636-46 [17707234.001]
  • [Cites] J Cell Biol. 2007 Dec 31;179(7):1337-45 [18166648.001]
  • [Cites] Am J Hum Genet. 2008 Feb;82(2):283-9 [18252210.001]
  • [Cites] J Clin Invest. 2008 Jul;118(7):2600-8 [18521189.001]
  • [Cites] J Biol Chem. 2008 Jul 11;283(28):19478-88 [18480059.001]
  • [Cites] Hum Mutat. 2009 Jan;30(1):79-84 [18634034.001]
  • [Cites] Mol Cell Biol. 2009 Apr;29(8):2278-95 [19223465.001]
  • [Cites] Clin Cancer Res. 2009 Oct 1;15(19):6292-300 [19789321.001]
  • [Cites] J Clin Oncol. 2010 Apr 1;28(10):1721-6 [20194856.001]
  • [Cites] Nat Rev Cancer. 2010 Jun;10(6):389-402 [20495573.001]
  • [Cites] J Cell Biochem. 2010 Jun 1;110(3):609-19 [20512922.001]
  • [Cites] Mol Cell. 2010 Oct 8;40(1):9-21 [20932471.001]
  • [Cites] Mol Cell. 2010 Oct 8;40(1):22-33 [20932472.001]
  • [Cites] Nat Cell Biol. 2010 Nov;12(11):1086-93 [20953199.001]
  • [Cites] Genes Dev. 2010 Nov 15;24(22):2531-42 [20966048.001]
  • [Cites] Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3116-23 [21282610.001]
  • [Cites] Cancer Res. 2011 Aug 1;71(15):5175-81 [21676885.001]
  • [Cites] Mutat Res. 2011 Dec 1;717(1-2):25-31 [21540042.001]
  • [Cites] EMBO J. 2012 Jan 4;31(1):110-23 [21983900.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):217-27 [22028396.001]
  • [Cites] CA Cancer J Clin. 2012 Jan-Feb;62(1):10-29 [22237781.001]
  • [Cites] Carcinogenesis. 2012 Feb;33(2):338-47 [22114071.001]
  • [Cites] Carcinogenesis. 2012 Mar;33(3):581-6 [22166496.001]
  • [Cites] Carcinogenesis. 2012 May;33(5):1046-54 [22331473.001]
  • [Cites] Asian Pac J Cancer Prev. 2012;13(3):851-6 [22631660.001]
  • [Cites] Cancer Res. 2012 Jul 1;72(13):3217-27 [22556262.001]
  • [Cites] Int J Cancer. 2012 Sep 15;131(6):1318-22 [22095217.001]
  • [Cites] Cancer Genet. 2012 Jul-Aug;205(7-8):373-6 [22867998.001]
  • [Cites] Carcinogenesis. 2012 Nov;33(11):2147-54 [22859270.001]
  • [Cites] J Exp Clin Cancer Res. 2012;31:54 [22672859.001]
  • [Cites] Mol Cell. 2002 Jun;9(6):1201-13 [12086618.001]
  • (PMID = 24146953.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / MIRN502 microRNA, human; 0 / MicroRNAs; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase; EC 2.1.1.43 / SETD8 protein, human
  • [Other-IDs] NLM/ PMC3795636
  •  go-up   go-down


68. Wang H, Ge B, Mair VH, Cai D, Xie C, Zhang Q, Zhou H, Zhu H: Molecular genetic analysis of remains from Lamadong cemetery, Liaoning, China. Am J Phys Anthropol; 2007 Nov;134(3):404-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To investigate the genetic structure of the Murong Xianbei population and to address its genetic relationships with other nomadic tribes at a molecular level, we analyzed the control region sequences and coding-region single nucleotide polymorphism markers of mtDNA from the remains of the Lamadong cemetery of the Three-Yan Culture of the Murong Xianbei population, which is dated to 1,600-1,700 years ago.
  • The frequencies of these haplogroups were compared with those of Asian populations and a multidimensional scaling graph was constructed to investigate relationships with other Asian populations.
  • The results indicate that the genetic structure of the Lamadong population is very intricate; it has haplogroups prevalent in both the Eastern Asian and the Siberian populations, showing more affinity with the Eastern Asian populations.
  • [MeSH-major] Asian Continental Ancestry Group / history. Evolution, Molecular

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17632796.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 9007-49-2 / DNA
  •  go-up   go-down


69. Garrod MG, Allen LH, Haan MN, Green R, Miller JW: Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics. Eur J Clin Nutr; 2010 May;64(5):503-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This polymorphism may affect the affinity of TC for B12 and subsequent delivery of B12 to tissues.
  • The holoTC/total B12 ratio was lower in the 776GG group compared with the 776CC group (P=0.04).
  • CONCLUSIONS: This population of older Latinos has a lower prevalence of the TC 776GG variant than reported for Caucasian populations.

  • MedlinePlus Health Information. consumer health - Hispanic American Health.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CYANOCOBALAMIN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Med Genet. 2007 Jun;44(6):363-7 [17220211.001]
  • [Cites] Scand J Clin Lab Invest. 2007;67(2):247-51 [17366004.001]
  • [Cites] Mol Genet Metab. 2008 May;94(1):112-9 [18226574.001]
  • [Cites] Prenat Diagn. 2008 Jun;28(6):485-93 [18435414.001]
  • [Cites] Clin Chem. 2008 Jul;54(7):1210-7 [18451312.001]
  • [Cites] Food Nutr Bull. 2008 Jun;29(2 Suppl):S116-25 [18709886.001]
  • [Cites] Blood. 2009 Jan 1;113(1):186-92 [18779389.001]
  • [Cites] N Engl J Med. 1999 May 13;340(19):1449-54 [10320382.001]
  • [Cites] Blood. 2001 Feb 15;97(4):1092-8 [11159542.001]
  • [Cites] Clin Chem. 2001 Nov;47(11):1993-2002 [11673368.001]
  • [Cites] Blood. 2001 Dec 1;98(12):3497-9 [11732507.001]
  • [Cites] Clin Chem. 2002 Mar;48(3):526-32 [11861443.001]
  • [Cites] Blood. 2002 Jul 15;100(2):718-20 [12091374.001]
  • [Cites] Eur J Hum Genet. 2002 Jul;10(7):433-8 [12107818.001]
  • [Cites] Neurology. 2002 Aug 13;59(3):383-91 [12177372.001]
  • [Cites] Clin Chem. 2002 Sep;48(9):1383-9 [12194912.001]
  • [Cites] Clin Chem. 2002 Oct;48(10):1768-71 [12324494.001]
  • [Cites] Hum Reprod. 2002 Dec;17(12):3033-6 [12456598.001]
  • [Cites] J Am Geriatr Soc. 2003 Feb;51(2):169-77 [12558712.001]
  • [Cites] Thromb Res. 2002 Nov 1;108(2-3):127-31 [12590948.001]
  • [Cites] Am J Clin Nutr. 2003 May;77(5):1241-7 [12716678.001]
  • [Cites] Neurosci Lett. 2003 Jul 3;344(3):189-92 [12812837.001]
  • [Cites] Clin Chem. 2003 Jul;49(7):1195-8 [12816923.001]
  • [Cites] Clin Chem Lab Med. 2003 Nov;41(11):1478-88 [14656029.001]
  • [Cites] Clin Chem Lab Med. 2003 Nov;41(11):1532-6 [14656037.001]
  • [Cites] Mol Genet Metab. 2003 Nov;80(3):364 [14680986.001]
  • [Cites] Clin Biochem. 2004 Feb;37(2):128-33 [14725943.001]
  • [Cites] Dement Geriatr Cogn Disord. 2004;17(3):215-21 [14739547.001]
  • [Cites] Biochim Biophys Acta. 1994 Oct 18;1219(2):515-20 [7918650.001]
  • [Cites] Clin Chem. 1997 Apr;43(4):687-8 [9105275.001]
  • [Cites] Annu Rev Med. 1998;49:31-62 [9509248.001]
  • [Cites] Biochem Biophys Res Commun. 1998 Oct 29;251(3):769-74 [9790985.001]
  • [Cites] Eur J Clin Invest. 1999 Apr;29(4):321-9 [10231344.001]
  • [Cites] Birth Defects Res A Clin Mol Teratol. 2005 Apr;73(4):239-44 [15782407.001]
  • [Cites] Am J Clin Nutr. 2005 Jun;81(6):1436-41 [15941899.001]
  • [Cites] Mol Hum Reprod. 2005 Jul;11(7):477-80 [16123074.001]
  • [Cites] Clin Chem Lab Med. 2005;43(10):1048-51 [16197296.001]
  • [Cites] Clin Chem. 2006 Jan;52(1):129-37 [16239338.001]
  • [Cites] Clin Chem. 2006 Feb;52(2):278-85 [16384886.001]
  • [Cites] Hum Mutat. 2006 Mar;27(3):294 [16470748.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4386-91 [16537422.001]
  • [Cites] Thromb Res. 2007;119(2):183-8 [16530812.001]
  • [Cites] Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141B(8):947-56 [16917939.001]
  • [Cites] Thromb Res. 2007;119(5):571-7 [16820193.001]
  • [Cites] Hum Mutat. 2007 Sep;28(9):856-65 [17436311.001]
  • (PMID = 20216556.001).
  • [ISSN] 1476-5640
  • [Journal-full-title] European journal of clinical nutrition
  • [ISO-abbreviation] Eur J Clin Nutr
  • [Language] ENG
  • [Grant] United States / NIA NIH HHS / AG / AG012975-12A2; United States / NIDDK NIH HHS / DK / R01 DK060753; United States / NIA NIH HHS / AG / AG12975; United States / NIA NIH HHS / AG / R03 AG033751; United States / NIA NIH HHS / AG / R01 AG012975-12A2; United States / NIA NIH HHS / AG / R01 AG012975
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Transcobalamins; 0LVT1QZ0BA / Homocysteine; 12001-76-2 / Vitamin B Complex; 8LL8S712J7 / Methylmalonic Acid; P6YC3EG204 / Vitamin B 12
  • [Other-IDs] NLM/ NIHMS169860; NLM/ PMC2864787
  •  go-up   go-down


70. Nettle D, Harriss L: Genetic and linguistic affinities between human populations in Eurasia and West Africa. Hum Biol; 2003 Jun;75(3):331-44
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic and linguistic affinities between human populations in Eurasia and West Africa.
  • This study examines the relationship between genetic distance and linguistic affiliation for five regional sets of populations from Eurasia and West Africa.
  • Human genetic and linguistic diversity have been proposed to be generally correlated, either through a direct link, whereby linguistic and genetic affiliations reflect the same past population processes, or an indirect one, where the evolution of the two types of diversity is independent but conditioned by the same geographical factors.
  • Clear relationships between genetic distances and linguistic relatedness are detectable in Europe and East and Central Asia, but not in the Middle East, Southeast Asia, or West Africa.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. European Continental Ancestry Group / genetics. Gene Frequency. Language
  • [MeSH-minor] Africa, Western. Asia. Europe. Genetics, Population. Humans

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 14527197.001).
  • [ISSN] 0018-7143
  • [Journal-full-title] Human biology
  • [ISO-abbreviation] Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


71. Chong KT, Ho WF, Koo SH, Thompson P, Lee EJ: Distribution of the FcgammaRIIIa 176 F/V polymorphism amongst healthy Chinese, Malays and Asian Indians in Singapore. Br J Clin Pharmacol; 2007 Mar;63(3):328-32
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS: To determine and compare the distribution of the FcgammaRIIIa 176 F/V polymorphism across three ethnically distinct populations (Chinese, Asian Indians and Malays) in Singapore.
  • METHODS: The FcgammaRIIIa 176 F/V polymorphism was genotyped by direct sequencing from genomic DNA samples obtained from normal healthy Chinese, Asian Indians and Malays (n = 192 from each population).
  • RESULTS: The allelic frequencies of the high binding affinity FcgammaRIIIa 176 V allele for Chinese, Asian Indians and Malays were 35%, 33% and 46%, respectively (F allele frequencies were 65%, 67% and 54%, respectively).
  • Genotype distributions were found to conform to the Hardy-Weinberg law (P > 0.05) in each group. chi(2) comparisons revealed significant differences in the genotype distributions of the FcgammaRIIIa 176 V/F polymorphism of Malays from the other two populations (Chinese and Asian Indians).
  • However, no significant difference in the genotype distributions of the FcgammaRIIIa 176 V/F polymorphism was observed between Chinese and Asian Indian populations.
  • These observations provide the fundamentals on which future disease associations may be built and also present important implications for the design of therapeutic regimens amongst various ethnic groups.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Gene Frequency. Polymorphism, Genetic / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arthritis Rheum. 1995 Mar;38(3):306-14 [7880183.001]
  • [Cites] J Immunol Methods. 1994 Aug 1;173(2):207-17 [8046255.001]
  • [Cites] Br J Haematol. 1998 Jun;101(4):779-82 [9674755.001]
  • [Cites] Immunogenetics. 1998 Aug;48(3):222-32 [9683667.001]
  • [Cites] Arthritis Rheum. 1998 Oct;41(10):1813-8 [9778222.001]
  • [Cites] J Clin Oncol. 2004 Dec 1;22(23):4717-24 [15483014.001]
  • [Cites] J Clin Oncol. 2005 Jan 20;23(3):474-81 [15659493.001]
  • [Cites] J Neuroimmunol. 2005 May;162(1-2):157-64 [15833371.001]
  • [Cites] Immunology. 2005 Jul;115(3):416-21 [15946259.001]
  • [Cites] Blood. 1999 Dec 15;94(12):4220-32 [10590067.001]
  • [Cites] Arthritis Rheum. 2000 Apr;43(4):735-9 [10765917.001]
  • [Cites] J Immunol Methods. 2000 Aug 28;242(1-2):127-32 [10986395.001]
  • [Cites] Br J Haematol. 2001 Jun;113(3):596-9 [11380443.001]
  • [Cites] Lupus. 2001;10(7):466-72 [11480843.001]
  • [Cites] J Neuroimmunol. 2001 Aug 30;118(2):187-93 [11498253.001]
  • [Cites] Blood. 2002 Feb 1;99(3):754-8 [11806974.001]
  • [Cites] Rheumatol Int. 2002 Apr;21(6):222-6 [12036208.001]
  • [Cites] J Rheumatol. 2002 Jun;29(6):1135-40 [12064825.001]
  • [Cites] Ann Rheum Dis. 2002 Nov;61(11):1021-3 [12379528.001]
  • [Cites] Kidney Int. 2003 Apr;63(4):1475-82 [12631364.001]
  • [Cites] Rheumatology (Oxford). 2003 Apr;42(4):528-33 [12649399.001]
  • [Cites] Tissue Antigens. 2003 May;61(5):374-83 [12753656.001]
  • [Cites] Immunogenetics. 2003 Jul;55(4):240-6 [12830330.001]
  • [Cites] Genes Immun. 2004 Mar;5(2):130-7 [14737097.001]
  • [Cites] Ann Rheum Dis. 2004 Jul;63(7):877-80 [15194589.001]
  • [Cites] J Exp Med. 1989 Aug 1;170(2):481-97 [2526846.001]
  • [Cites] J Biol Chem. 1992 Aug 5;267(22):15692-700 [1379234.001]
  • [Cites] Ann N Y Acad Sci. 1997 Apr 5;815:282-95 [9186665.001]
  • (PMID = 16981896.001).
  • [ISSN] 0306-5251
  • [Journal-full-title] British journal of clinical pharmacology
  • [ISO-abbreviation] Br J Clin Pharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2000731
  •  go-up   go-down


72. Zhen J, He L, Xu Y, Zhao J, Yu Q, Zou H, Sun G, Deng Z: Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population. Tissue Antigens; 2015 Nov;86(5):362-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.
  • The allelic polymorphism of KIR2DL2/2DL3 has been shown to influence their binding specificity and affinity to the HLA-C1 ligands.
  • The present study aims to investigate the distribution of the allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population using sequence-specific primer polymerase chain reaction (PCR-SSP) and PCR-sequence-based typing (SBT) at the entire coding sequence.
  • KIR2DL3 showed a high degree of diversity in the study population with 15 alleles detected including 8 novel ones.
  • The predominant 2DL3 allele in the study population is 2DL3*00101 (92.81%) followed by 2DL3*00201 (24.18%), 2DL3*023 (4.25%), and 2DL3*00109 (1.31%).
  • [MeSH-minor] Asian Continental Ancestry Group. China. Female. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
  • (PMID = 26423800.001).
  • [ISSN] 1399-0039
  • [Journal-full-title] Tissue antigens
  • [ISO-abbreviation] Tissue Antigens
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / KIR2DL2 protein, human; 0 / KIR2DL3 protein, human; 0 / Receptors, KIR2DL2; 0 / Receptors, KIR2DL3
  • [Keywords] NOTNLM ; allelic polymorphism / killer cell immunoglobulin-like receptor / sequence-based typing / southern Chinese Han
  •  go-up   go-down


73. Welch JS, Dobson C, Chopra S: Immunodiagnosis of Entamoeba histolytica and Ascaris lumbricoides infections in Caucasian and aboriginal Australians. Trans R Soc Trop Med Hyg; 1986;80(2):240-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The immunodiagnostic efficiency of an indirect immunofluorescence test (IFAT) and in vitro lymphocyte proliferative responsiveness (cell mediated immunity test, CMIT) used to measure the immunological responses of individuals with known natural Entamoeba histolytica and Ascaris lumbricoides infections, was studied under survey conditions. E. histolytica was common among Aborigines from Cherbourg, Kowanyama and Central Australia, but it was not found in Brisbane Caucasians.
  • Immunodiagnosis for A. lumbricoides was made using an antigen prepared by affinity chromatography.
  • Diagnosis based on frequency distribution of immunological data gave valid assessment of the number of infected individuals in each population studied.
  • [MeSH-minor] Adolescent. Adult. Antibodies / analysis. Antigens, Helminth / immunology. Australia. Child. Child, Preschool. Entamoeba histolytica. European Continental Ancestry Group. Fluorescent Antibody Technique. Humans. Immunity, Cellular. Infant. Infant, Newborn. Lymphocyte Activation. Oceanic Ancestry Group

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 2878514.001).
  • [ISSN] 0035-9203
  • [Journal-full-title] Transactions of the Royal Society of Tropical Medicine and Hygiene
  • [ISO-abbreviation] Trans. R. Soc. Trop. Med. Hyg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Antibodies; 0 / Antigens, Helminth
  •  go-up   go-down


74. Unmack PJ, Bagley JC, Adams M, Hammer MP, Johnson JB: Molecular phylogeny and phylogeography of the Australian freshwater fish genus Galaxiella, with an emphasis on dwarf galaxias (G. pusilla). PLoS One; 2012;7(6):e38433
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The freshwater fauna of Southern Australia is primarily restricted to the southwestern and southeastern corners of the continent, and is separated by a large, arid region that is inhospitable to this biota.
  • Here, we employed phylogenetic and phylogeographic approaches to evaluate the effect of this barrier on a group of four galaxiid fish species (Galaxiella) endemic to temperate Southern Australia.
  • We also tested if continental shelf width has influenced connectivity among populations during low sea levels when rivers, now isolated, could have been connected.
  • These data also allowed us to assess species boundaries, to refine phylogenetic affinities, and to estimate species ages.
  • Each Galaxiella species showed high levels of genetic divergences between all but the most proximate populations.
  • Despite extensive drainage connections during recent low sea levels in southeastern Australia, populations of both species within G. pusilla maintained high levels of genetic structure.
  • All populations experienced Late Pleistocene-Holocene population growth, possibly in response to the relaxation of arid conditions after the last glacial maximum.
  • High levels of genetic divergence and the discovery of new cryptic species have important implications for the conservation of this already threatened group of freshwater species.

  • Dryad Digital Repository. supplemental materials - Dryad Digital Repository .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nature. 2000 Feb 24;403(6772):853-8 [10706275.001]
  • [Cites] Mol Ecol. 2011 Nov;20(21):4388-94 [21951722.001]
  • [Cites] Am J Hum Genet. 2001 Apr;68(4):978-89 [11254454.001]
  • [Cites] Mol Biol Evol. 2001 Jun;18(6):1001-13 [11371589.001]
  • [Cites] J Forensic Sci. 2001 May;46(3):681-4 [11373007.001]
  • [Cites] Syst Biol. 2000 Dec;49(4):777-95 [12116439.001]
  • [Cites] Mol Biol Evol. 2002 Dec;19(12):2092-100 [12446801.001]
  • [Cites] Mol Ecol. 2002 Dec;11(12):2623-35 [12453245.001]
  • [Cites] Syst Biol. 2003 Dec;52(6):757-80 [14668116.001]
  • [Cites] Genetics. 1989 Nov;123(3):585-95 [2513255.001]
  • [Cites] Genetics. 1992 Jun;131(2):479-91 [1644282.001]
  • [Cites] Biochim Biophys Acta. 1993 Jul 26;1143(3):243-71 [8329437.001]
  • [Cites] Genetics. 1997 Oct;147(2):915-25 [9335623.001]
  • [Cites] Bioinformatics. 1998;14(9):817-8 [9918953.001]
  • [Cites] Mol Phylogenet Evol. 1999 Feb;11(1):1-12 [10082606.001]
  • [Cites] Mol Biol Evol. 2005 May;22(5):1185-92 [15703244.001]
  • [Cites] Mol Phylogenet Evol. 2006 May;39(2):573-9 [16384717.001]
  • [Cites] Bioinformatics. 2006 Nov 1;22(21):2688-90 [16928733.001]
  • [Cites] Mol Phylogenet Evol. 2007 Jun;43(3):1106-17 [17434758.001]
  • [Cites] Mol Phylogenet Evol. 2007 Jul;44(1):371-85 [17275343.001]
  • [Cites] BMC Evol Biol. 2007;7:214 [17996036.001]
  • [Cites] Mol Biol Evol. 2008 Apr;25(4):624-33 [18281273.001]
  • [Cites] Syst Biol. 2008 Oct;57(5):758-71 [18853362.001]
  • [Cites] Mol Ecol. 2008 Dec;17(24):5291-314 [19120999.001]
  • [Cites] Bioinformatics. 2009 Jun 1;25(11):1451-2 [19346325.001]
  • [Cites] Mol Biol Evol. 2010 Mar;27(3):570-80 [19906793.001]
  • [Cites] Bioinformatics. 2010 Aug 1;26(15):1899-900 [20427515.001]
  • [Cites] Mol Biol Evol. 2011 Oct;28(10):2731-9 [21546353.001]
  • [Cites] Syst Biol. 2011 Dec;60(6):797-812 [21551126.001]
  • [Cites] Mol Ecol. 2000 Oct;9(10):1657-9 [11050560.001]
  • (PMID = 22693638.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3367931
  •  go-up   go-down


75. Deka R: A genetic survey in four Mongoloid populations of the Garo Hills, India. Anthropol Anz; 1984 Mar;42(1):41-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A genetic survey in four Mongoloid populations of the Garo Hills, India.
  • Four Mongoloid populations, viz., Garo , Hajong , Rabha and Koch, belonging to the Tibetoburman language family of Garo Hills, India, were examined for blood types ( A1A2BO , Rh, MN), secretor factor, ability to taste PTC and cerumen types.
  • R1 is the commonest chromosome in all the groups followed by R2.
  • Frequency of gene M is very high in all these populations.
  • Dry cerumen gene is frequent in these Mongoloid groups.
  • In general, the Garo Hills populations show closer affinity to the Mongoloids of Northeast India in respect of gene frequencies.
  • [MeSH-major] Asian Continental Ancestry Group. Gene Frequency. Genetics, Population
  • [MeSH-minor] ABO Blood-Group System / genetics. Chromosome Mapping. Humans. India. MNSs Blood-Group System / genetics. Phenotype. Rh-Hr Blood-Group System / genetics

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 6426374.001).
  • [ISSN] 0003-5548
  • [Journal-full-title] Anthropologischer Anzeiger; Bericht über die biologisch-anthropologische Literatur
  • [ISO-abbreviation] Anthropol Anz
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] GERMANY, WEST
  • [Chemical-registry-number] 0 / ABO Blood-Group System; 0 / MNSs Blood-Group System; 0 / Rh-Hr Blood-Group System
  •  go-up   go-down


76. de Azevedo S, Bortolini MC, Bonatto SL, Hünemeier T, Santos FR, González-José R: Ancient remains and the first peopling of the Americas: Reassessing the Hoyo Negro skull. Am J Phys Anthropol; 2015 Nov;158(3):514-21
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Here, we aim to further explore the morphological affinities of this specimen with a set of comparative cranial samples covering ancient and modern periods from Asia and the Americas.
  • RESULTS: Even thought the Principal Component Analysis suggests that the Hoyo Negro skull falls in a subregion of the morphospace occupied by both "Paleoamericans" and some modern Native Americans, the Discriminant analyses suggest greater affinity with a modern Native American sample.
  • DISCUSSION: These results reinforce the idea that the original population that first occupied the New World carried high levels of within-group variation, which we have suggested previously on a synthetic model for the settlement of the Americas.
  • [MeSH-major] American Native Continental Ancestry Group. Human Migration. Skull / anatomy & histology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2015 Wiley Periodicals, Inc.
  • (PMID = 26174009.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Paleoamericans / craniofacial morphology / geometric morphometrics / recurrent gene flow model
  •  go-up   go-down


77. Xiao B, Gu SM, Li MJ, Li J, Tao B, Wang Y, Wang Y, Zuo S, Shen Y, Yu Y, Chen D, Chen G, Kong D, Tang J, Liu Q, Chen DR, Liu Y, Alberti S, Dovizio M, Landolfi R, Mucci L, Miao PZ, Gao P, Zhu DL, Wang J, Li B, Patrignani P, Yu Y: Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population. Arterioscler Thromb Vasc Biol; 2015 Jul;35(7):1687-95
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population.
  • OBJECTIVE: To investigate whether rs12731181 (A→G) interrupted miR-590-3p-mediated suppression of the prostaglandin F2α receptor (FP) and whether it is associated with essential hypertension in the Chinese population.
  • APPROACH AND RESULTS: We found that miR-590-3p regulates human FP gene expression by binding to its 3'-untranslated region. rs12731181 (A→G) altered the binding affinity between miR-590-3p and its FP 3'-untranslated region target, thus reducing the suppression of FP expression, which, in turn, enhanced FP receptor-mediated contractility of vascular smooth muscle cells.
  • An association study was performed to analyze the relationship between the FP gene and essential hypertension in the Han Chinese population.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Hypertension / genetics. MicroRNAs / genetics. Receptors, Prostaglandin / genetics

  • Genetic Alliance. consumer health - Essential hypertension.
  • MedlinePlus Health Information. consumer health - High Blood Pressure.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2015 American Heart Association, Inc.
  • (PMID = 25977569.001).
  • [ISSN] 1524-4636
  • [Journal-full-title] Arteriosclerosis, thrombosis, and vascular biology
  • [ISO-abbreviation] Arterioscler. Thromb. Vasc. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / MIRN590 microRNA, human; 0 / MicroRNAs; 0 / Receptors, Prostaglandin; 0 / prostaglandin F2alpha receptor; Hypertension, Essential
  • [Keywords] NOTNLM ; essential / hypertension / microRNAs / polymorphism / prostaglandin F2α receptor / single nucleotide
  •  go-up   go-down


78. Honma W, Gautier A, Paule I, Yamaguchi M, Lowe PJ: Ethnic sensitivity assessment of pharmacokinetics and pharmacodynamics of omalizumab with dosing table expansion. Drug Metab Pharmacokinet; 2016 Jun;31(3):173-84
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The population PKPD analysis was conducted using data from the nine studies included originally in the European application of dosing table expansion together with three Japanese clinical studies to assess the influence of the ethnicity.
  • Statistically significant differences between the ethnic groups were detected.
  • The model described the primary pharmacology in Caucasian and Japanese patients, both adult and paediatric, with simulations showing that the interplay between the clearance, volume and binding affinity parameters was such that there was no clinical impact of the Japanese ethnic differences on either drug PK or free IgE suppression and hence the required posology.
  • [MeSH-minor] Adolescent. Adult. Aged. Asian Continental Ancestry Group. Body Weight. Child. Child, Preschool. Drug Administration Schedule. European Continental Ancestry Group. Humans. Immunoglobulin E / blood. Japan. Middle Aged. Models, Biological. Young Adult

  • Hazardous Substances Data Bank. Omalizumab .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2016 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 27238573.001).
  • [ISSN] 1880-0920
  • [Journal-full-title] Drug metabolism and pharmacokinetics
  • [ISO-abbreviation] Drug Metab. Pharmacokinet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Asthmatic Agents; 2P471X1Z11 / Omalizumab; 37341-29-0 / Immunoglobulin E
  • [Keywords] NOTNLM ; Allergic asthma / Anti-immunoglobulin E / Dosing table / Modeling and simulation / Omalizumab
  •  go-up   go-down


79. Karmakar B, Yakovenko K, Kobyliansky E: Dermatoglyphic sexual dimorphism: finger and palmar qualitative characteristics in five endogamous populations of West Bengal, India. Anthropol Anz; 2002 Sep;60(3):273-92
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dermatoglyphic sexual dimorphism: finger and palmar qualitative characteristics in five endogamous populations of West Bengal, India.
  • Five hundred families from five different endogamous populations encompassing the main social rank in the caste hierarchy of the same geographical area of West Bengal, India, were analyzed to present variation in qualitative pattern types on fingers and palms.
  • Sex dimorphism, homogeneous in all populations, suggests common characteristics of dermatoglyphic patterns.
  • The pattern types are not uniformly distributed on 10 fingers and palmar configurational areas.
  • However, most of these observations are homogeneous in nature, in both sexes among 5 populations.
  • But the two sets of results on fingers and palms are not exactly the same.
  • Palmar dermatoglyphic relationship reflects the better caste affinities, perhaps due to embryological development, having relatively a longer growth period compared to fingers (Cummins 1929).
  • The present findings indicate that the qualitative dermatoglyphic affinities conform to the known ethnohistorical background of these populations, which correspond also to the results of quantitative dermatoglyphics as well as serological and biochemical markers of these populations.
  • These observations indicate that these population groups have a common genetic background and thus traditional grouping of Indian populations on the basis of caste hierarchy may not be a reflection of the genetic origin of the population.
  • In dermatoglyphic affinities, both qualitative and quantitative traits therefore may be quite useful in tracing the ethnohistorical background of these populations.
  • [MeSH-major] Dermatoglyphics. European Continental Ancestry Group / genetics. Sex Characteristics
  • [MeSH-minor] Consanguinity. Female. Gene Frequency / genetics. Genetics, Population. Humans. India. Male. Social Class

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12378794.001).
  • [ISSN] 0003-5548
  • [Journal-full-title] Anthropologischer Anzeiger; Bericht über die biologisch-anthropologische Literatur
  • [ISO-abbreviation] Anthropol Anz
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


80. Spurdle AB, Jenkins T: The origins of the Lemba "Black Jews" of southern Africa: evidence from p12F2 and other Y-chromosome markers. Am J Hum Genet; 1996 Nov;59(5):1126-33
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Lemba are a southern African Bantu-speaking population claiming Jewish ancestry.
  • Allele frequencies at four different Y-specific polymorphic loci, as well as extended-haplotype frequencies that included data from several loci, were analyzed in an attempt to establish the genetic affinities and origins of the Lemba.
  • These Y-specific genetic findings are consistent with Lemba oral tradition, and analysis of the history of Jewish people and their association with Africa indicates that the historical facts are not incompatible with theories concerning the origin of the Lemba.
  • [MeSH-major] African Continental Ancestry Group. Jews. Y Chromosome
  • [MeSH-minor] Africa, Southern / ethnology. Alleles. Gene Frequency. Genetics, Population. Haplotypes. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 1992 Jun;50(6):1301-7 [1598910.001]
  • [Cites] Am J Hum Genet. 1992 Jan;50(1):107-25 [1729883.001]
  • [Cites] Isr J Med Sci. 1991 May;27(5):245-51 [2050504.001]
  • [Cites] Ann Hum Genet. 1990 Oct;54(Pt 4):287-96 [2285217.001]
  • [Cites] Gene Geogr. 1987 Dec;1(3):201-6 [2908692.001]
  • [Cites] Science. 1985 Dec 20;230(4732):1403-6 [2999986.001]
  • [Cites] Am J Hum Genet. 1971 Sep;23(5):513-32 [5092600.001]
  • [Cites] Mol Biol Evol. 1994 Sep;11(5):749-61 [7968488.001]
  • [Cites] Am J Hum Genet. 1994 Feb;54(2):319-30 [8304348.001]
  • [Cites] Am J Hum Genet. 1994 Feb;54(2):303-18 [8304347.001]
  • [Cites] Ann Hum Genet. 1993 Jan;57(Pt 1):55-64 [8101437.001]
  • [Cites] Am J Hum Genet. 1996 Mar;58(3):595-608 [8644719.001]
  • (PMID = 8900243.001).
  • [ISSN] 0002-9297
  • [Journal-full-title] American journal of human genetics
  • [ISO-abbreviation] Am. J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Other-IDs] NLM/ PMC1914832
  •  go-up   go-down


81. Boonprasert K, Ruengweerayut R, Aunpad R, Satarug S, Na-Bangchang K: Expression of metallothionein isoforms in peripheral blood leukocytes from Thai population residing in cadmium-contaminated areas. Environ Toxicol Pharmacol; 2012 Nov;34(3):935-40
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of metallothionein isoforms in peripheral blood leukocytes from Thai population residing in cadmium-contaminated areas.
  • Metallothionein (MT) is a group of proteins with high cadmium (Cd) affinity and with a potential role in Cd transportation and detoxification.
  • The aim of the present study was to investigate the relationship between MT (MT-1A, MT-2A, and MT-3 isoforms) gene expression level in peripheral blood leukocytes and Cd-associated renal injury in non-occupational exposed Thai population.
  • These results suggest that MT gene expression may reflect susceptibility of the exposed population to Cd-induced renal dysfunction.
  • [MeSH-minor] Adult. Asian Continental Ancestry Group. Biomarkers / metabolism. Dose-Response Relationship, Drug. Environmental Exposure / statistics & numerical data. Female. Gene Expression. Humans. Leukocytes, Mononuclear. Male. Middle Aged. Protein Isoforms. Thailand

  • Hazardous Substances Data Bank. CADMIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2012 Elsevier B.V. All rights reserved.
  • (PMID = 22981465.001).
  • [ISSN] 1872-7077
  • [Journal-full-title] Environmental toxicology and pharmacology
  • [ISO-abbreviation] Environ. Toxicol. Pharmacol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Environmental Pollutants; 0 / Protein Isoforms; 00BH33GNGH / Cadmium; 9038-94-2 / Metallothionein
  •  go-up   go-down


82. Malyarchuk B, Derenko M, Denisova G, Khoyt S, Woźniak M, Grzybowski T, Zakharov I: Y-chromosome diversity in the Kalmyks at the ethnical and tribal levels. J Hum Genet; 2013 Dec;58(12):804-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The Mongolic-speaking Kalmyks currently inhabiting the steppes of the Volga region have Central Asian ancestry and are organized into the tribal groups.
  • Among these tribes, the Dörwöds and Torguuds, as well as the Kalmyks collectively as an ethnic group, showed relatively close genetic affinities to each other and to the Mongols and Altaian Kazakhs, whereas the Khoshuuds were clearly separated from all of them, gathering with the Manchu, Tibetans or Evenks (depending on the algorithm used to calculate genetic distances).
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Chromosomes, Human, Y / genetics. Ethnic Groups / genetics. European Continental Ancestry Group / genetics. Polymorphism, Genetic / genetics
  • [MeSH-minor] Gene Flow / genetics. Gene Frequency / genetics. Genetics, Population. Haplotypes. Humans. Male. Microsatellite Repeats / genetics

  • Nature Publishing Group. Nature Publishing Group (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 24132124.001).
  • [ISSN] 1435-232X
  • [Journal-full-title] Journal of human genetics
  • [ISO-abbreviation] J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


83. Saha A, Sharma S, Bhat A, Pandit A, Bamezai R: Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow. J Hum Genet; 2005;50(1):49-51
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow.
  • Four binary polymorphisms and four multiallelic short tandem repeat (STR) loci from the nonrecombining region of the human Y-chromosome were typed in different Indian population groups from Uttar Pradeh (UP), Bihar (BI), Punjab (PUNJ), and Bengal (WB) speaking the Indo-Aryan dialects and from South India (SI) with the root in the Dravidian language.
  • The phylogenetic analyses indicate a high degree of population admixture and a greater genetic proximity for the studied population groups when compared with other world populations.
  • [MeSH-minor] Alleles. Ethnic Groups / genetics. European Continental Ancestry Group / genetics. Evolution, Molecular. Gene Frequency. Genetic Variation. Humans. India. Male. Polymorphism, Genetic. Tandem Repeat Sequences

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • Nature Publishing Group. Nature Publishing Group (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15611834.001).
  • [ISSN] 1434-5161
  • [Journal-full-title] Journal of human genetics
  • [ISO-abbreviation] J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


84. Gray SJ, Wiebusch B, Akol HA: Cross-sectional growth of pastoralist Karimojong and Turkana children. Am J Phys Anthropol; 2004 Oct;125(2):193-202
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this study, we compare cross-sectional growth in two Nilotic pastoralist populations, the Turkana and Karimojong of northern East Africa.
  • Until the middle of the 18th century, these two groups constituted one population, and their genetic affinities consequently are assumed to be strong.
  • Growth in stature of the two groups is remarkably similar, whereas the pattern of ponderal growth varies, particularly in infancy and adolescence.
  • Both groups demonstrate the linear adult physique that is characteristic of savanna-dwelling peoples in East Africa, but the Karimojong are heavier and fatter after early childhood.
  • [MeSH-minor] Adolescent. Adult. Africa. African Continental Ancestry Group. Body Composition. Body Mass Index. Child. Child, Preschool. Cross-Sectional Studies. Ethnic Groups. Female. Humans. Infant. Infant, Newborn. Male. Rural Population

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15365984.001).
  • [ISSN] 0002-9483
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


85. Khrunin A, Verbenko D, Nikitina K, Limborska S: Regional differences in the genetic variability of Finno-Ugric speaking Komi populations. Am J Hum Biol; 2007 Nov-Dec;19(6):741-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regional differences in the genetic variability of Finno-Ugric speaking Komi populations.
  • The Komi (Komi-Zyryan) people are one of the most numerous ethnic groups belonging to the Finno-Ugric linguistic community.
  • Genetic variability was evaluated in two geographically distinct populations, the Izhemski and Priluzski Komi.
  • Some data from our previous studies of TP53, 3'ApoB, and D1S80 variability were involved in the comparison of Komi with other Eastern European populations.
  • Multidimensional scaling analysis of genetic distances was used for the evaluation of genetic relationships between populations.
  • The results revealed some affinity between Priluzski Komi and Eastern Slavonic populations, and significant segregation of Izhemski Komi from other ethnic groups studied.
  • [MeSH-major] Ethnic Groups / genetics. Genetics, Population. Polymorphism, Genetic / genetics
  • [MeSH-minor] Asian Continental Ancestry Group / genetics. Base Sequence / genetics. European Continental Ancestry Group / genetics. Geography. Humans. Polymerase Chain Reaction. Russia

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2007 Wiley-Liss, Inc.
  • (PMID = 17691096.001).
  • [ISSN] 1042-0533
  • [Journal-full-title] American journal of human biology : the official journal of the Human Biology Council
  • [ISO-abbreviation] Am. J. Hum. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


86. Robinson JI, Carr IM, Cooper DL, Rashid LH, Martin SG, Emery P, Isaacs JD, Barton A, BRAGGSS, Wilson AG, Barrett JH, Morgan AW: Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis. Hum Mutat; 2012 Apr;33(4):741-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.
  • The FCGR locus encoding the low-affinity Fcγ receptors (FcγR) for immunoglobulin G has largely been missed by genome-wide association studies due to complications with structural variation and segmental duplication.
  • [MeSH-minor] Case-Control Studies. European Continental Ancestry Group / genetics. GPI-Linked Proteins / genetics. Genetics, Population. Humans. Models, Genetic. Neutrophils / metabolism. Reproducibility of Results

  • Genetic Alliance. consumer health - Arthritis.
  • Genetic Alliance. consumer health - Rheumatoid arthritis.
  • MedlinePlus Health Information. consumer health - Rheumatoid Arthritis.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • SciCrunch. OMIM: Data: Gene Annotation .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2012 Wiley Periodicals, Inc.
  • (PMID = 22290871.001).
  • [ISSN] 1098-1004
  • [Journal-full-title] Human mutation
  • [ISO-abbreviation] Hum. Mutat.
  • [Language] eng
  • [Grant] United Kingdom / Arthritis Research UK / / 18475; United Kingdom / Arthritis Research UK / / 19764; United Kingdom / Arthritis Research UK / / 13569; United Kingdom / Arthritis Research UK / / 18066
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / FCGR2B protein, human; 0 / FCGR3A protein, human; 0 / FCGR3B protein, human; 0 / GPI-Linked Proteins; 0 / Receptors, IgG
  •  go-up   go-down


87. Veiga-da-Cunha M, Delplanque J, Gillain A, Bonthron DT, Boutin P, Van Schaftingen E, Froguel P: Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians. Diabetologia; 2003 May;46(5):704-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: The most frequent mutation (Pro446Leu) had a similar allele frequency in the obese (0.63) and normal weight (0.64) subjects and did not affect the properties of GKRP.
  • Mutation Arg518Gln, replacing a conserved residue, led to a marked decrease in the affinity of GKRP for both fructose 6-phosphate and fructose 1-phosphate and to a destabilization of GKRP.
  • However, this mutation did not co-segregate with obesity in the single family in which it was found.
  • CONCLUSIONS/INTERPRETATION: Mutations that affect the properties of GKRP are found in the French population, but they do not seem to account for the linkage between the 2p23 locus and quantitative markers of obesity.
  • [MeSH-minor] Adaptor Proteins, Signal Transducing. Amino Acid Sequence. Animals. Base Sequence. Chromosome Mapping. Codon, Terminator / genetics. DNA Primers. European Continental Ancestry Group. Female. France. Glucokinase / metabolism. Haemophilus influenzae / genetics. Humans. Male. Molecular Sequence Data. Mutagenesis, Site-Directed. Pedigree. Sequence Alignment. Sequence Homology, Amino Acid

  • MedlinePlus Health Information. consumer health - Obesity.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] EMBO J. 1996 Dec 2;15(23):6541-51 [8978681.001]
  • [Cites] FASEB J. 1994 Apr 1;8(6):414-9 [8168691.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):113-4 [9771699.001]
  • [Cites] Diabetes. 2002 Jul;51(7):2056-65 [12086933.001]
  • [Cites] Nature. 2000 Apr 6;404(6778):661-71 [10766253.001]
  • [Cites] Eur J Biochem. 1989 Jan 15;179(1):179-84 [2917560.001]
  • [Cites] Genomics. 1998 Apr 1;49(1):137-42 [9570959.001]
  • [Cites] JAMA. 1999 Oct 27;282(16):1523-9 [10546691.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Apr;86(8):2766-70 [2565038.001]
  • [Cites] Nat Genet. 1997 Jul;16(3):303-6 [9207799.001]
  • [Cites] Diabetes. 1994 Mar;43(3):389-95 [7508874.001]
  • [Cites] J Clin Endocrinol Metab. 1999 Apr;84(4):1483-6 [10199800.001]
  • [Cites] Diabetes. 1999 Mar;48(3):643-4 [10078570.001]
  • [Cites] Nat Genet. 1997 Mar;15(3):273-6 [9054940.001]
  • [Cites] Diabetes. 2000 May;49(5):693-700 [10905475.001]
  • [Cites] Diabetes. 1999 Sep;48(9):1763-72 [10480606.001]
  • [Cites] Nat Genet. 1998 Nov;20(3):304-8 [9806554.001]
  • [Cites] Eur J Biochem. 1990 Jul 31;191(2):483-9 [2384095.001]
  • [Cites] Int J Obes Relat Metab Disord. 2001 Dec;25 Suppl 5:S68-72 [11840219.001]
  • [Cites] Diabetes. 2001 Jan;50(1):1-11 [11147773.001]
  • [Cites] Diabetes. 1990 Jun;39(6):647-52 [2189759.001]
  • [Cites] Proc Natl Acad Sci U S A. 1979 Sep;76(9):4350-4 [388439.001]
  • [Cites] J Biol Chem. 1996 Mar 15;271(11):6292-7 [8626423.001]
  • [Cites] Nat Genet. 1998 Jun;19(2):155-7 [9620771.001]
  • [Cites] J Neurochem. 2000 May;74(5):1848-57 [10800927.001]
  • [Cites] J Biol Chem. 1999 Jan 1;274(1):305-15 [9867845.001]
  • [Cites] Nature. 1998 Mar 26;392(6674):398-401 [9537324.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Feb;87(2):867-9 [11836334.001]
  • [Cites] J Biol Chem. 2000 Mar 17;275(11):7826-31 [10713097.001]
  • [Cites] Mamm Genome. 1995 Aug;6(8):532-6 [8589523.001]
  • [Cites] Exp Biol Med (Maywood). 2001 Dec;226(11):991-6 [11743134.001]
  • [Cites] Anal Biochem. 1999 Nov 1;275(1):93-7 [10542113.001]
  • [Cites] Clin Chem. 1979 Sep;25(9):1531-46 [380843.001]
  • [Cites] Eur J Hum Genet. 1999 Sep;7(6):717-23 [10482962.001]
  • [Cites] Nucleic Acids Res. 1987 Oct 26;15(20):8125-48 [3313277.001]
  • [Cites] Diabetologia. 2000 Dec;43(12):1554-7 [11151766.001]
  • [Cites] Nat Genet. 1998 Mar;18(3):213-5 [9500540.001]
  • [Cites] Science. 1996 Sep 13;273(5281):1561-4 [8703220.001]
  • [Cites] J Mol Biol. 1986 May 5;189(1):113-30 [3537305.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14511-6 [10588736.001]
  • [Cites] Am J Hum Genet. 1989 Aug;45(2):337-9 [2631699.001]
  • [Cites] J Neurochem. 2002 Jan;80(1):45-53 [11796742.001]
  • [Cites] J Biol Chem. 2002 Mar 8;277(10):8466-73 [11756407.001]
  • (PMID = 12739015.001).
  • [ISSN] 0012-186X
  • [Journal-full-title] Diabetologia
  • [ISO-abbreviation] Diabetologia
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0000477
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Carrier Proteins; 0 / Codon, Terminator; 0 / DNA Primers; 0 / GCKR protein, human; 0 / glucokinase regulatory protein; EC 2.7.1.2 / Glucokinase
  •  go-up   go-down


88. Herrera B, Peart D, Hernandez N, Spradley K, Hubbe M: Morphological variation among late holocene Mexicans: Implications for discussions about the human occupation of the Americas. Am J Phys Anthropol; 2017 May;163(1):75-84
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: Cranial morphology has previously been used to estimate phylogenetic relationships among populations, and has been an important tool in the reconstruction of ancient human dispersals across the planet.
  • MATERIALS AND METHODS: We explore the cranial morphological affinities of three late Holocene Mexican series, in relation to ancient and modern crania from North and South America, Australo-Melanesia, and East Asia.
  • Morphological affinities were assessed through Mahalanobis Distances, and represented via Multidimensional Scaling and Ward's Linkage Cluster analysis.
  • RESULTS: Our results show Mexican groups share morphological affinities with the Native American series, but do not cluster together as would be expected.
  • The minimum F<sub>ST</sub> estimates show between-group variation in the Americas is higher than the Asian or Australo-Melanesian populations, and that Mexican series have high between-group variance (F<sub>ST</sub>  = 0.124), compared to the geographically larger South America (F<sub>ST</sub>  = 0.116) and North America (F<sub>ST</sub>  = 0.076).
  • DISCUSSION: These results show that the Mexican series share morphological affinities with the East Asian series, but maintains high levels of between-group variation, similar to South America.
  • This supports the suggestion that the high phenotypic variation seen the Americas is not a result of its size, as it can be found in more constricted areas, such as the Mexican territory.
  • [MeSH-major] American Native Continental Ancestry Group / classification. Human Migration
  • [MeSH-minor] Anthropology, Physical. Cephalometry. Continental Population Groups / classification. Female. Humans. Male. Mexico. Skull / anatomy & histology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2017 Wiley Periodicals, Inc.
  • (PMID = 28218396.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; FST / Mexico / craniometric variation / morphological affinity
  •  go-up   go-down


89. Martiniano R, Coelho C, Ferreira MT, Neves MJ, Pinhasi R, Bradley DG: Genetic evidence of African slavery at the beginning of the trans-Atlantic slave trade. Sci Rep; 2014;4:5994
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We obtained random short autosomal sequence reads from seven individuals: two from the latter site and five from the Leprosarium and used these to call SNP identities and estimate ancestral affinities with modern reference data.
  • The two discard deposit burials each gave African affinity signals, which were further refined toward modern West African or Bantu genotyped samples.
  • [MeSH-major] African Continental Ancestry Group / genetics. Slaves
  • [MeSH-minor] Archaeology. DNA, Mitochondrial / analysis. DNA, Mitochondrial / chemistry. Genetics, Population. Genotype. High-Throughput Nucleotide Sequencing. History, 15th Century. History, 16th Century. Humans. Polymorphism, Single Nucleotide. Principal Component Analysis. Sequence Analysis, DNA

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nucleic Acids Res. 2007;35(17):5717-28 [17715147.001]
  • [Cites] Am J Hum Genet. 2007 Sep;81(3):559-75 [17701901.001]
  • [Cites] Bioinformatics. 2009 Jul 15;25(14):1754-60 [19451168.001]
  • [Cites] Bioinformatics. 2009 Aug 15;25(16):2078-9 [19505943.001]
  • [Cites] Genome Res. 2009 Sep;19(9):1655-64 [19648217.001]
  • [Cites] Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):786-91 [20080753.001]
  • [Cites] Cold Spring Harb Protoc. 2010 Jun;2010(6):pdb.prot5448 [20516186.001]
  • [Cites] Hum Mutat. 2011 Jan;32(1):25-32 [20960467.001]
  • [Cites] Science. 2011 Oct 7;334(6052):94-8 [21940856.001]
  • [Cites] Mitochondrion. 2011 Nov;11(6):924-8 [21875693.001]
  • [Cites] PLoS One. 2012;7(3):e34131 [22479540.001]
  • [Cites] Science. 2012 Apr 27;336(6080):466-9 [22539720.001]
  • [Cites] BMC Genomics. 2012;13:178 [22574660.001]
  • [Cites] Emerg Infect Dis. 2013 May;19(5):837-9 [23697340.001]
  • [Cites] Nature. 2013 Jul 4;499(7456):74-8 [23803765.001]
  • [Cites] Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2229-34 [24469802.001]
  • [Cites] Am J Phys Anthropol. 1998 Apr;105(4):539-43 [9584894.001]
  • [Cites] Nat Genet. 1999 Oct;23(2):147 [10508508.001]
  • [Cites] Bioinformatics. 2007 Jul 15;23(14):1801-6 [17485429.001]
  • [Cites] PLoS Genet. 2006 Dec;2(12):e190 [17194218.001]
  • [Cites] Science. 2008 Feb 22;319(5866):1100-4 [18292342.001]
  • (PMID = 25104065.001).
  • [ISSN] 2045-2322
  • [Journal-full-title] Scientific reports
  • [ISO-abbreviation] Sci Rep
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  • [Other-IDs] NLM/ PMC4125989
  •  go-up   go-down


90. Li YC, Huang W, Tian JY, Chen XQ, Kong QP: Exploring the maternal history of the Tai people. J Hum Genet; 2016 Aug;61(8):721-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, a systematic genetic study of the whole Tai people is still lacking, thus making the population structure as well as the demographic history of this group uninvestigated from genetic perspective.
  • Here we extensively analyzed the variants of hypervariable segments I and II (HVS-I and HVS-II) of mitochondrial DNA (mtDNA) of 719 Tai samples from 19 populations, covering virtually all of the current Tai people's residences.
  • We observed a general close genetic affinity of the Tai people, reflecting a common origin of this group.
  • In line with their diverse cultures and languages, substantial genetic divergences can be observed among different Tai populations that could be attributable to assimilation of maternal components from neighboring populations.
  • Our study further implied the advent of rice agriculture in Mainland Southeast Asia at ∼5 kya (kilo years ago) had greatly promoted the population expansion of the Tai people.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. DNA, Mitochondrial / genetics. Genetic Variation. Genetics, Population
  • [MeSH-minor] Asia, Southeastern. Cluster Analysis. Geography. Haplotypes. Humans. Population Dynamics. Sequence Analysis, DNA

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • Nature Publishing Group. Nature Publishing Group (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 2004 May;74(5):856-65 [15042512.001]
  • [Cites] Hum Genet. 2003 Oct;113(5):391-405 [12938036.001]
  • [Cites] Nat Commun. 2013;4:2599 [24121720.001]
  • [Cites] Am J Hum Genet. 2000 Sep;67(3):718-26 [10924403.001]
  • [Cites] Am J Phys Anthropol. 2008 Dec;137(4):425-40 [18615504.001]
  • [Cites] Sci Rep. 2015 Mar 26;5:9473 [25826227.001]
  • [Cites] Am J Hum Genet. 2008 Jul;83(1):142-6; author reply 146-7 [18606310.001]
  • [Cites] Am J Hum Genet. 1996 Oct;59(4):935-45 [8808611.001]
  • [Cites] Mol Biol Evol. 2011 Feb;28(2):1013-24 [20978040.001]
  • [Cites] J Hum Genet. 2001;46(4):211-20 [11322662.001]
  • [Cites] PLoS One. 2011;6(10):e25835 [21998705.001]
  • [Cites] Am J Hum Genet. 2009 Jun;84(6):740-59 [19500773.001]
  • [Cites] Science. 2009 Aug 7;325(5941):710-4 [19661421.001]
  • [Cites] Mol Neurobiol. 2016 Aug;53(6):3873-81 [26162319.001]
  • [Cites] Syst Biol. 2004 Oct;53(5):793-808 [15545256.001]
  • [Cites] Mol Biol Evol. 1999 Jan;16(1):37-48 [10331250.001]
  • [Cites] Evol Bioinform Online. 2007 Feb 23;1:47-50 [19325852.001]
  • [Cites] Am J Hum Genet. 2002 Mar;70(3):635-51 [11836649.001]
  • [Cites] Hum Mol Genet. 2006 Jul 1;15(13):2076-86 [16714301.001]
  • [Cites] PLoS One. 2009;4(1):e4210 [19148289.001]
  • [Cites] Mol Biol Evol. 2011 Jan;28(1):513-22 [20713468.001]
  • [Cites] Sci Rep. 2015 Feb 11;5:8377 [25669617.001]
  • [Cites] Am J Phys Anthropol. 2007 Dec;134(4):481-8 [17668442.001]
  • [Cites] Mol Biol Evol. 2004 Dec;21(12):2265-80 [15317881.001]
  • [Cites] Nat Genet. 1999 Oct;23(2):147 [10508508.001]
  • [Cites] Am J Phys Anthropol. 2002 May;118(1):63-76 [11953946.001]
  • [Cites] Mitochondrion. 2013 Jul;13(4):360-3 [23632257.001]
  • [Cites] BMC Evol Biol. 2007 Nov 08;7:214 [17996036.001]
  • [Cites] J Hum Genet. 2001;46(3):115-25 [11310578.001]
  • [Cites] BMC Evol Biol. 2014 Jan 28;14:17 [24467713.001]
  • [Cites] BMC Evol Biol. 2007 Mar 28;7:47 [17389048.001]
  • [Cites] Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6044-9 [21444824.001]
  • (PMID = 27098877.001).
  • [ISSN] 1435-232X
  • [Journal-full-title] Journal of human genetics
  • [ISO-abbreviation] J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  •  go-up   go-down


91. Miyazaki H, Yamaguchi Y, Takehara T: Dental arch and palate in Taiwan aboriginals--Ami, Bunun, Paiwan and Rukai tribes. Arch Oral Biol; 1993 Sep;38(9):729-35
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These results indicate that Ami and Bunun, and Paiwan and Rukai, respectively, have close affinities.
  • [MeSH-major] Asian Continental Ancestry Group. Dental Arch / anatomy & histology. Oceanic Ancestry Group. Palate / anatomy & histology
  • [MeSH-minor] Adult. Cephalometry. Continental Population Groups. Female. Humans. Japan. Male. Maxilla / anatomy & histology. Phylogeny. Reference Standards. Taiwan

  • MedlinePlus Health Information. consumer health - Native Hawaiian and Pacific Islander Health.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 8240079.001).
  • [ISSN] 0003-9969
  • [Journal-full-title] Archives of oral biology
  • [ISO-abbreviation] Arch. Oral Biol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] ENGLAND
  •  go-up   go-down


92. Asano K, Matsushita T, Umeno J, Hosono N, Takahashi A, Kawaguchi T, Matsumoto T, Matsui T, Kakuta Y, Kinouchi Y, Shimosegawa T, Hosokawa M, Arimura Y, Shinomura Y, Kiyohara Y, Tsunoda T, Kamatani N, Iida M, Nakamura Y, Kubo M: A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet; 2009 Dec;41(12):1325-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
  • Although previous studies have indicated that there is a genetic contribution to the pathogenesis of ulcerative colitis, the genes influencing susceptibility to the disease have not been fully determined.
  • rs1801274 is a nonsynonymous SNP of FCGR2A that is reported to have a critical effect on receptor binding affinity for IgG and to be associated with other autoimmune diseases.
  • [MeSH-minor] Antiporters / genetics. Asian Continental Ancestry Group / genetics. Chloride-Bicarbonate Antiporters. Chromosomes, Human, Pair 13 / genetics. Disease Susceptibility / epidemiology. Genome-Wide Association Study. Humans. Japan. Major Histocompatibility Complex / genetics. Polymorphism, Single Nucleotide. Population Groups. Receptors, IgG / genetics

  • Genetic Alliance. consumer health - Ulcerative Colitis.
  • MedlinePlus Health Information. consumer health - Ulcerative Colitis.
  • COS Scholar Universe. author profiles.
  • SciCrunch. OMIM: Data: Gene Annotation .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19915573.001).
  • [ISSN] 1546-1718
  • [Journal-full-title] Nature genetics
  • [ISO-abbreviation] Nat. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiporters; 0 / Chloride-Bicarbonate Antiporters; 0 / FCGR2A protein, human; 0 / Receptors, IgG; 0 / SLC26A3 protein, human
  •  go-up   go-down


93. Li JT, Zhong BY, Xu HH, Qiao SY, Wang G, Huang J, Fan HZ, Zhao HC: Associations between NBS1 Polymorphisms and Colorectal Cancer in Chinese Population. PLoS One; 2015;10(7):e0132332
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Associations between NBS1 Polymorphisms and Colorectal Cancer in Chinese Population.
  • Further functional experiments demonstrated that the rs2735383C allele in the NBS1 disrupted the binding affinity of has-miR-509-5p to the NBS1 3'-UTR in colorectal cancer cells, affecting the NBS1 transcriptional activity and expression level.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Cell Cycle Proteins / genetics. Colorectal Neoplasms / genetics. Genetic Association Studies. Genetic Predisposition to Disease. Nuclear Proteins / genetics. Polymorphism, Single Nucleotide / genetics

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer Res. 2013 Aug 15;73(16):5151-62 [23796562.001]
  • [Cites] DNA Cell Biol. 2012 Jul;31(7):1182-6 [22413803.001]
  • [Cites] Mutagenesis. 2013 Nov;28(6):683-97 [24113799.001]
  • [Cites] Cancer Causes Control. 2014 Jan;25(1):11-23 [24166361.001]
  • [Cites] Gastroenterology. 2014 Jun;146(7):1714-26.e5 [24631494.001]
  • [Cites] Sci Rep. 2014;4:6700 [25332048.001]
  • [Cites] PLoS One. 2014;9(11):e113513 [25405996.001]
  • [Cites] Carcinogenesis. 2014 Dec;35(12):2687-97 [25239642.001]
  • [Cites] Biochem J. 2009 Feb 1;417(3):639-50 [19133841.001]
  • [Cites] Breast Cancer Res Treat. 2009 Jun;115(3):613-22 [18551366.001]
  • [Cites] Gene. 2009 Nov 1;447(1):12-7 [19635536.001]
  • [Cites] Cell. 2009 Oct 2;139(1):87-99 [19804755.001]
  • [Cites] J Appl Genet. 2010;51(3):343-52 [20720310.001]
  • [Cites] Am J Clin Nutr. 2010 Sep;92(3):471-90 [20729339.001]
  • [Cites] Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Feb;31(2):213-7 [21215087.001]
  • [Cites] CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90 [21296855.001]
  • [Cites] Genes Dev. 2011 Apr 1;25(7):685-700 [21406551.001]
  • [Cites] Curr Med Res Opin. 2011 Jul;27(7):1295-302 [21561390.001]
  • [Cites] Mol Carcinog. 2011 Sep;50(9):689-96 [21656575.001]
  • [Cites] Carcinogenesis. 2012 Feb;33(2):338-47 [22114071.001]
  • [Cites] Tumour Biol. 2013 Apr;34(2):1255-62 [23381647.001]
  • [Cites] Genes Dev. 2000 Apr 15;14(8):927-39 [10783165.001]
  • [Cites] Nat Genet. 2001 Mar;27(3):247-54 [11242102.001]
  • [Cites] Nature. 2001 May 17;411(6835):366-74 [11357144.001]
  • [Cites] Science. 2002 May 3;296(5569):922-7 [11934988.001]
  • [Cites] Mutat Res. 2002 Jun;511(2):145-78 [12052432.001]
  • [Cites] Nucleic Acids Res. 2002 Nov 15;30(22):4815-22 [12433983.001]
  • [Cites] Mol Cancer Res. 2003 Jul;1(9):674-81 [12861053.001]
  • [Cites] Oncol Rep. 2003 Sep-Oct;10(5):1615-23 [12883749.001]
  • [Cites] Oncol Rep. 2004 Apr;11(4):917-22 [15010895.001]
  • [Cites] Chromosoma. 2004 Sep;113(2):53-61 [15258809.001]
  • [Cites] J Radiat Res. 2004 Dec;45(4):473-8 [15635255.001]
  • [Cites] Nat Cell Biol. 2005 Jul;7(7):648-50 [15990895.001]
  • [Cites] J Biol Chem. 2005 Nov 25;280(47):39594-600 [16188882.001]
  • [Cites] Carcinogenesis. 2006 Nov;27(11):2209-16 [16714331.001]
  • [Cites] Lung Cancer. 2006 Dec;54(3):285-92 [17034901.001]
  • [Cites] Leuk Lymphoma. 2006 Dec;47(12):2567-83 [17169801.001]
  • [Cites] BMC Med Genet. 2008;9:69 [18638378.001]
  • [Cites] Carcinogenesis. 2012 Mar;33(3):581-6 [22166496.001]
  • [Cites] Tumour Biol. 2013 Oct;34(5):2753-7 [23765759.001]
  • (PMID = 26186548.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 3' Untranslated Regions; 0 / Cell Cycle Proteins; 0 / NBN protein, human; 0 / Nuclear Proteins; 0 / RNA, Messenger; EC 1.13.12.- / Luciferases
  • [Other-IDs] NLM/ PMC4505902
  •  go-up   go-down


94. Caplan R, Cheung SC, Omenn GS: Electrophoretic profiles of aqueous-soluble proteins of human cerebral cortex: population and developmental characteristics. J Neurochem; 1974 Apr;22(4):517-20
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Electrophoretic profiles of aqueous-soluble proteins of human cerebral cortex: population and developmental characteristics.
  • [MeSH-minor] Adolescent. Adult. African Continental Ancestry Group. Animals. Asian Continental Ancestry Group. Basal Ganglia / analysis. Brain Stem / analysis. Cerebellum / analysis. Child. Chromatography, Affinity. Electrophoresis, Disc. Electrophoresis, Polyacrylamide Gel. European Continental Ancestry Group. Fetus. Genetics, Population. Haplorhini. Humans. Infant. Macaca. Mice. Mice, Inbred Strains. Sodium Dodecyl Sulfate. Species Specificity. Thalamus / analysis

  • Hazardous Substances Data Bank. SODIUM LAURYL SULFATE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 4208422.001).
  • [ISSN] 0022-3042
  • [Journal-full-title] Journal of neurochemistry
  • [ISO-abbreviation] J. Neurochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Nerve Tissue Proteins; 368GB5141J / Sodium Dodecyl Sulfate
  •  go-up   go-down


95. Rowold DJ, Perez-Benedico D, Stojkovic O, Garcia-Bertrand R, Herrera RJ: On the Bantu expansion. Gene; 2016 Nov 15;593(1):48-57
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Here we report the results of fine resolution Y chromosomal analyses (Y-SNP and Y-STR) of 267 Bantu-speaking males from three populations located in the southeast region of Africa.
  • In an effort to determine the relative Y chromosomal affinities of these three genotyped populations, the findings are interpreted in the context of 74 geographically and ethnically targeted African reference populations representing four major ethno-linguistic groups (Afro-Asiatic, Niger Kordofanin, Khoisan and Pygmoid).
  • In this investigation, we detected a general similarity in the Y chromosome lineages among the geographically dispersed Bantu-speaking populations suggesting a shared heritage and the shallow time depth of the Bantu Expansion.
  • Also, micro-variations in the Bantu Y chromosomal composition across the continent highlight location-specific gene flow patterns with non-Bantu-speaking populations (Khoisan, Pygmy, Afro-Asiatic).
  • Our Y chromosomal results also indicate that the three Bantu-speaking Southeast populations genotyped exhibit unique gene flow patterns involving Eurasian populations but fail to reveal a prevailing genetic affinity to East or Central African Bantu-speaking groups.
  • No evidence was observed linking the B2a haplogroup detected in the genotyped Southeast African Bantu-speaking populations to gene flow from contemporary Khoisan groups.
  • [MeSH-major] African Continental Ancestry Group / genetics. Chromosomes, Human, Y / genetics. Gene Flow. Polymorphism, Single Nucleotide

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2016 Elsevier B.V. All rights reserved.
  • (PMID = 27451076.001).
  • [ISSN] 1879-0038
  • [Journal-full-title] Gene
  • [ISO-abbreviation] Gene
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Bantu / Forensic analysis / Population genetics / South East Africans / Y-STRs / Y-chromosome
  •  go-up   go-down


96. Yu LW, Wang F, Yang XY, Sun SN, Zheng YF, Li BB, Gui YH, Wang HY: Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population. Sci Rep; 2016 Apr 01;6:23662
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population.
  • In this study, we sequenced the 2 kb region upstream of the TBX20 transcription start site in 228 CHD patients and 292 controls in a Han Chinese population.
  • The electrophoretic mobility shift assay suggested that TBX20 minor alleles may exhibit higher binding affinity with certain transcription repressors.
  • Our results indicate that a moderately lower TBX20 activity potentially reduces CHD risk in the Han Chinese population, providing new insight in the study of CHD etiology.
  • [MeSH-minor] Alleles. Asian Continental Ancestry Group / genetics. Cell Line. China / epidemiology. DNA / metabolism. Ethnic Groups / genetics. Gene Frequency. Genetic Predisposition to Disease. Haplotypes / genetics. Humans. Linkage Disequilibrium. Nuclear Proteins / metabolism. Protein Binding. Transcription, Genetic

  • Genetic Alliance. consumer health - Congenital Heart Defects.
  • Genetic Alliance. consumer health - Heart Defects.
  • MedlinePlus Health Information. consumer health - Congenital Heart Defects.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Mol Cell Cardiol. 2013 Jul;60:84-9 [23583740.001]
  • [Cites] Ann Med. 2012 Nov;44(7):680-93 [21923612.001]
  • [Cites] Nat Genet. 2013 Jul;45(7):822-4 [23708191.001]
  • [Cites] Development. 2013 Aug;140(15):3176-87 [23824573.001]
  • [Cites] Biochimie. 2013 Sep;95(9):1807-9 [23727221.001]
  • [Cites] Sci Rep. 2015;5:8506 [25687545.001]
  • [Cites] Gene. 2015 Apr 15;560(2):129-36 [25680289.001]
  • [Cites] Pediatr Cardiol. 2015 Apr;36(4):737-42 [25487630.001]
  • [Cites] Sci Rep. 2015;5:13120 [26278011.001]
  • [Cites] Cell. 2001 Sep 21;106(6):709-21 [11572777.001]
  • [Cites] Development. 2005 May;132(10):2475-87 [15843407.001]
  • [Cites] Development. 2005 May;132(10):2463-74 [15843409.001]
  • [Cites] Development. 2005 May;132(10):2451-62 [15843414.001]
  • [Cites] Science. 2006 Sep 29;313(5795):1922-7 [17008524.001]
  • [Cites] Cell Mol Life Sci. 2007 Mar;64(6):646-60 [17380306.001]
  • [Cites] Circ Res. 2009 Aug 28;105(5):442-52 [19661464.001]
  • [Cites] Herz. 2010 Jan;35(1):19-26 [20140785.001]
  • [Cites] Clin Res Cardiol. 2010 Mar;99(3):137-47 [20012542.001]
  • [Cites] Clin Genet. 2010 Aug;78(2):103-23 [20497191.001]
  • [Cites] J Clin Invest. 2011 Feb;121(2):534-44 [21266775.001]
  • [Cites] PLoS Genet. 2011 Feb;7(2):e1001313 [21379568.001]
  • [Cites] Cardiovasc Res. 2011 Jul 15;91(2):212-22 [21498422.001]
  • [Cites] J Am Coll Cardiol. 2011 Nov 15;58(21):2241-7 [22078432.001]
  • [Cites] Dev Biol. 2011 Dec 15;360(2):381-90 [21983003.001]
  • [Cites] Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E154-63 [22203979.001]
  • [Cites] Dev Biol. 2012 Mar 1;363(1):234-46 [22226977.001]
  • [Cites] Gene. 2012 May 25;500(1):28-31 [22465533.001]
  • [Cites] Dev Cell. 2012 Aug 14;23(2):280-91 [22898775.001]
  • [Cites] Mol Cell Biochem. 2012 Nov;370(1-2):53-8 [22801995.001]
  • [Cites] Nat Genet. 2013 Jul;45(7):818-21 [23708190.001]
  • (PMID = 27034249.001).
  • [ISSN] 2045-2322
  • [Journal-full-title] Scientific reports
  • [ISO-abbreviation] Sci Rep
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Nuclear Proteins; 0 / T-Box Domain Proteins; 0 / TBX20 protein, human; 9007-49-2 / DNA
  • [Other-IDs] NLM/ PMC4817057
  •  go-up   go-down


97. Fu L, Zhao Y, Lu J, Shi J, Li C, Liu H, Li Y: Functional single nucleotide polymorphism-1026C/A of inducible nitric oxide synthase gene with increased YY1-binding affinity is associated with hypertension in a Chinese Han population. J Hypertens; 2009 May;27(5):991-1000
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Functional single nucleotide polymorphism-1026C/A of inducible nitric oxide synthase gene with increased YY1-binding affinity is associated with hypertension in a Chinese Han population.
  • Lipopolysaccharide, an inflammatory stimulating factor, could induce YY1 to augment DNA-binding affinity; it could also be involved in the inhibited transcriptional activity of the iNOS promoter with allele C.
  • CONCLUSION: We thus conclude that iNOS-1026C/A with a change in YY1-binding affinity is associated with hypertension under the affect of inflammatory-stimulating factors.
  • [MeSH-major] Asian Continental Ancestry Group / genetics. Genetics, Population. Hypertension / genetics. Nitric Oxide Synthase Type II / genetics. Polymorphism, Single Nucleotide

  • MedlinePlus Health Information. consumer health - High Blood Pressure.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19402223.001).
  • [ISSN] 1473-5598
  • [Journal-full-title] Journal of hypertension
  • [ISO-abbreviation] J. Hypertens.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / YY1 Transcription Factor; 0 / YY1 protein, human; EC 1.14.13.39 / Nitric Oxide Synthase Type II
  •  go-up   go-down


98. Misawa S: [Application of genetic polymorphisms in blood to forensic anthropology]. Nihon Hoigaku Zasshi; 1991 Aug;45(4):263-76
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 1. The Ainu subjects and, as controls, Wajin subjects obtained in the District of Hokkaido, were studied for blood groups, serum groups and red cell enzyme groups.
  • In considering the high frequencies of Fya and Agx genes, low incidence K gene and Rh negative type, and existence of Di (a+) type, it is conceivable that the distribution of these blood group in the Ainu are closer to those in Mongoloid than to those in Caucasoid.
  • The results of genetic distance analysis were in full agreement with the genetic affinity of the Ainu to the Mongoloid racial stock.
  • The most outstanding features of Negritos were as follows: Di (a+) type was found and all individuals were Lu (a-b +) and K-k+ types.
  • The existence of Dia gene and absence of both Lua and K genes are thought to suggest that the distribution of Negritos is quite close to that of Mongoloid populations.
  • Fy (a-b-) and Js (a+) types are not found in our study.
  • These results do not suggest similarity between Negritos and African.
  • [MeSH-major] Blood Group Antigens / genetics. Continental Population Groups / genetics. Forensic Medicine. Polymorphism, Genetic / genetics

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 1766142.001).
  • [ISSN] 0047-1887
  • [Journal-full-title] Nihon hōigaku zasshi = The Japanese journal of legal medicine
  • [ISO-abbreviation] Nihon Hoigaku Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] JAPAN
  • [Chemical-registry-number] 0 / Blood Group Antigens
  • [Number-of-references] 37
  •  go-up   go-down


99. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Inada T, Ozaki N, Iwata N: Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population. J Neural Transm (Vienna); 2008 Oct;115(10):1457-61
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population.
  • The majority of high affinity nicotine binding sites in the human brain have been implicated in heteropentameric alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptors; therefore, these two neuronal nicotinic acetylcholine receptors genes (CHRNA4 and CHRNB2) are considered to be attractive candidate genes for the pathophysiology of schizophrenia.
  • Using these tagging SNPs, we then conducted genetic association analysis of case-control samples (738 schizophrenia and 753 controls) in the Japanese population.
  • Our results suggest that CHRNA4 and CHRNB2 do not play a major role in Japanese schizophrenia.
  • [MeSH-minor] Adult. Asian Continental Ancestry Group / genetics. Case-Control Studies. Female. Genotype. Humans. Linkage Disequilibrium. Male. Middle Aged

  • Genetic Alliance. consumer health - Schizophrenia.
  • MedlinePlus Health Information. consumer health - Schizophrenia.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Hum Genet. 2004 Sep;75(3):353-62 [15272419.001]
  • [Cites] J Hum Genet. 2002;47(11):605-10 [12436197.001]
  • [Cites] Nucleic Acids Res. 2002 Jan 1;30(1):158-62 [11752280.001]
  • [Cites] Neurosci Biobehav Rev. 2005;29(6):1021-34 [15964073.001]
  • [Cites] Hum Hered. 2004;57(2):59-68 [15192278.001]
  • [Cites] Psychopharmacology (Berl). 1998 Aug;138(3-4):217-30 [9725745.001]
  • [Cites] Hum Mol Genet. 2007 Sep 15;16(18):2165-74 [17613539.001]
  • [Cites] Schizophr Res. 2008 Apr;101(1-3):1-8 [18282690.001]
  • [Cites] Mol Psychiatry. 2006 Mar;11(3):312-22, 223 [16314871.001]
  • [Cites] Ann Hum Genet. 2001 Mar;65(Pt 2):197-206 [11434330.001]
  • [Cites] Am J Psychiatry. 1996 Mar;153(3):321-30 [8610818.001]
  • [Cites] Psychol Med. 2004 Oct;34(7):1251-61 [15697051.001]
  • [Cites] Science. 2002 Jun 21;296(5576):2225-9 [12029063.001]
  • [Cites] J Subst Abuse. 1990;2(1):39-50 [2136102.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2786-91 [11226318.001]
  • [Cites] Bioinformatics. 2005 Jan 15;21(2):263-5 [15297300.001]
  • [Cites] J Neurosci. 2000 Sep 1;20(17 ):6431-41 [10964949.001]
  • [Cites] Addiction. 2003 Jan;98(1):23-31 [12492752.001]
  • [Cites] Nature. 2005 Jul 7;436(7047):103-7 [16001069.001]
  • [Cites] J Neurochem. 1997 Nov;69(5):2216-9 [9349569.001]
  • [Cites] Ann N Y Acad Sci. 2008 Oct;1139:70-82 [18991851.001]
  • [Cites] J Psychiatry Neurosci. 2007 Nov;32(6):412-6 [18043764.001]
  • [Cites] Cell Physiol Biochem. 2007;20(6):687-702 [17982252.001]
  • [Cites] Am J Hum Genet. 2004 Jul;75(1):112-21 [15154117.001]
  • [Cites] Schizophr Res. 2008 Apr;101(1-3):142-51 [18164594.001]
  • [Cites] Bioinformatics. 2003 Feb 12;19(3):376-82 [12584123.001]
  • [Cites] Biol Psychiatry. 1995 Jul 1;38(1):22-33 [7548469.001]
  • [Cites] Exp Brain Res. 2006 Sep;174(2):292-6 [16636791.001]
  • [Cites] Am J Psychiatry. 1986 Aug;143(8):993-7 [3487983.001]
  • [Cites] Arch Gen Psychiatry. 1998 Jan;55(1):67-74 [9435762.001]
  • [Cites] Hum Mol Genet. 2005 May 1;14(9):1211-9 [15790597.001]
  • (PMID = 18762859.001).
  • [ISSN] 0300-9564
  • [Journal-full-title] Journal of neural transmission (Vienna, Austria : 1996)
  • [ISO-abbreviation] J Neural Transm (Vienna)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Receptors, Nicotinic; 0 / nicotinic acetylcholine receptor alpha4 subunit; 0 / nicotinic receptor beta2
  •  go-up   go-down


100. Kulichová I, Fernandes V, Deme A, Nováčková J, Stenzl V, Novelletto A, Pereira L, Černý V: Internal diversification of non-Sub-Saharan haplogroups in Sahelian populations and the spread of pastoralism beyond the Sahara. Am J Phys Anthropol; 2017 Oct;164(2):424-434
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Internal diversification of non-Sub-Saharan haplogroups in Sahelian populations and the spread of pastoralism beyond the Sahara.
  • The most significant group among them are the Fulani who not only keep cattle breeds of possible West Eurasian ancestry, but form themselves a gene pool containing some paternally and maternally-transmitted West Eurasian haplogroups.
  • Similar age estimates were obtained for paternal lineage R1b-V88, which occurs today in the Fulani but also in other, mostly pastoral populations.
  • CONCLUSIONS: Despite the fact that animal domestication originated in the Near East ∼ 10 ka, and that it was from there that animals such as sheep, goats as well as cattle were introduced into Northeast Africa soon thereafter, contemporary cattle keepers in the Sahel/Savannah belt show uniparental genetic affinities that suggest the possibility of an ancient contact with an additional ancestral population of western Mediterranean ancestry.
  • [MeSH-major] African Continental Ancestry Group / genetics. Agriculture / history. DNA, Mitochondrial / genetics. Haplotypes / genetics. Human Migration / history
  • [MeSH-minor] Africa South of the Sahara. Anthropology, Physical. Chromosomes, Human, Y / genetics. Genetics, Population. History, Ancient. Humans. Male. Phylogeny

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2017 Wiley Periodicals, Inc.
  • (PMID = 28736914.001).
  • [ISSN] 1096-8644
  • [Journal-full-title] American journal of physical anthropology
  • [ISO-abbreviation] Am. J. Phys. Anthropol.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Mitochondrial
  • [Keywords] NOTNLM ; Fulani / Y chromosome / mtDNA / pastoralism / phylogeography
  •  go-up   go-down






Advertisement